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1. 发明申请

WO2012135679A3 NANOFIBER CONTAINING COMPOSITE STRUCTURES 审中-公开
标题翻译：含有纳米纤维的复合结构
公开(公告)号：WO2012135679A3
公开(公告)日：2013-03-14
申请号：PCT/US2012031549
申请日：2012-03-30
申请人： EMD MILLIPORE CORP , KAS ONUR Y , KOZLOV MIKHAL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY
发明人： KAS ONUR Y , KOZLOV MIKHAL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY
IPC分类号： B01D69/12 , B01D69/00 , B01D69/10 , B01D71/06 , D01D5/00
CPC分类号： B01D69/12 , B01D71/56 , B01D2323/39 , B01D2325/02 , D01D5/0084
摘要： A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
摘要翻译：一种复合液体过滤平台，其包括复合过滤介质，其特征在于在多孔膜上收集的电纺聚合物纳米纤维层。当使用时，多孔膜用作在聚合物纳米纤维层上游使用的预过滤器，以从流过复合过滤结构的液体流中除去颗粒。位于多孔膜下游的纳米纤维层用作临界过滤的保留层，以提供生物安全保证，并负责捕获细菌，支原体或病毒等微生物。本文提供的复合液体过滤平台相对于在粗糙无纺布上纺出的常规多孔膜或纳米纤维垫表现出渗透性优点。

2. 发明申请

WO2012135679A9 NANOFIBER CONTAINING COMPOSITE STRUCTURES 审中-公开
标题翻译：纳米纤维含复合结构
公开(公告)号：WO2012135679A9
公开(公告)日：2013-01-24
申请号：PCT/US2012031549
申请日：2012-03-30
申请人： EMD MILLIPORE CORP , KAS ONUR Y , KOZLOV MIKHAL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY
发明人： KAS ONUR Y , KOZLOV MIKHAL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY
IPC分类号： B01D69/12 , B01D69/00 , B01D69/10 , B01D71/06 , D01D5/00
CPC分类号： B01D69/12 , B01D71/56 , B01D2323/39 , B01D2325/02 , D01D5/0084
摘要： A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
摘要翻译：一种复合液体过滤平台，包括以多孔膜上收集的电纺聚合物纳米纤维层为特征的复合过滤介质。当使用时，多孔膜用作在聚合物纳米纤维层上游使用的预过滤器，以从流过复合过滤结构的液体流中去除颗粒。位于多孔膜下游的纳米纤维层被用作关键过滤的保留层，以提供生物安全保证，并负责捕获细菌，支原体或病毒等微生物。本文提供的复合液体过滤平台显示出优于常规的在粗糙非织造物上纺成的多孔膜或纳米纤维垫的渗透性优点。

3. 发明申请

WO2013013241A2 NANOFIBER CONTAINING COMPOSITE STRUCTURES 审中-公开
标题翻译：纳米纤维含复合结构
公开(公告)号：WO2013013241A2
公开(公告)日：2013-01-24
申请号：PCT/US2012047865
申请日：2012-07-23
申请人： EMD MILLIPORE CORP , KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , NHIEM DAVID , GODDARD PHILIP , LEON SHERRY ASHBY
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , NHIEM DAVID , GODDARD PHILIP , LEON SHERRY ASHBY
IPC分类号： B01D69/12 , B01D35/00 , B01D39/08 , B01D39/16 , B01D69/02
CPC分类号： B01D69/02 , B01D67/0004 , B01D2239/025 , B01D2239/0618 , B01D2239/0631 , B01D2239/0654 , B01D2323/39 , C02F1/444 , C02F2303/04
摘要： A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.
摘要翻译：一种纳米纤维液体过滤介质，其特征在于在光滑的无纺基材上生产的电纺聚合物纳米纤维层。

4. 发明申请

WO2012021308A3 METHOD FOR RETROVIRUS REMOVAL 审中-公开
标题翻译：去除血管病毒的方法
公开(公告)号：WO2012021308A3
公开(公告)日：2012-06-14
申请号：PCT/US2011045905
申请日：2011-07-29
申请人： EMD MILLIPORE CORP , KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , MOYA WILSON , GODDARD PHILIP , LEON SHERRY , HAO JIBIN
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , MOYA WILSON , GODDARD PHILIP , LEON SHERRY , HAO JIBIN
IPC分类号： C12Q1/70 , C12M1/12 , C12Q1/24 , C12R1/92
CPC分类号： B01D39/1623 , A61L2/022 , B01D39/00 , B01D39/04 , B01D39/14 , B01D39/16 , B01D39/1607 , B01D39/1615 , B01D39/18 , B01D61/14 , B01D67/0004 , B01D67/002 , B01D69/02 , B01D69/10 , B01D2239/0208 , B01D2239/0216 , B01D2239/025 , B01D2239/0442 , B01D2239/0631 , B01D2239/10 , B01D2239/1233 , B01D2323/39 , B01D2323/42 , B01D2325/20 , C12N7/00 , C12N2740/16051 , D01D1/02 , D01D5/0092 , D01F6/96 , D10B2505/04
摘要： A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism intention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.
摘要翻译：公开了一种从液体样品中除去逆转录病毒的方法和含有液体过滤介质的纳米纤维，同时具有高液体渗透性和高微生物意图。通过使液体通过含有大于约6的逆转录病毒LRV的过滤介质的多孔纳米纤维从液体中除去逆转录病毒，并且纳米纤维的直径为约10nm至约100nm。过滤介质可以是纤维电纺聚合物纳米纤维液体过滤介质垫的形式。

5. 发明专利

SG10201605328WA NANOFIBER CONTAINING COMPOSITE STRUCTURES 未知
公开(公告)号：SG10201605328WA
公开(公告)日：2016-08-30
申请号：SG10201605328W
申请日：2012-03-30
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY , GODDARD PHILIP
摘要： A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.

6. 发明专利

ES2886043T3 Estructuras compuestas que contienen nanofibras 未知
公开(公告)号：ES2886043T3
公开(公告)日：2021-12-16
申请号：ES12765651
申请日：2012-03-30
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , NHIEM DAVID , LEON SHERRY ASHBY , GODDARD PHILIP
IPC分类号： B01D69/12 , B01D69/00 , B01D69/10 , B01D71/06 , B01D71/56 , D01D5/00
摘要： Un medio compuesto poroso, caracterizado porque el medio compuesto poroso comprende: un prefiltro de membrana asimétrica porosa preparado por inversión de fase y que comprende un lado estrecho, un lado abierto y un tamaño de poro que aumenta de tamaño entre el lado estrecho y el lado abierto y una capa retentiva de nanofibras poliméricas electrohiladas porosas ubicada en el lado estrecho de la membrana, en donde las nanofibras electrohiladas tienen un diámetro promedio de fibra de 10 nm a 150 nm y la capa retentiva de nanofibras poliméricas electrohiladas porosas tiene un tamaño medio de poro que varía de 0,05 μm a 1 μm, una porosidad que varía de 80 % a 95 % y un grosor que varía de 1 μm a 100 μm, en donde el diámetro promedio de fibra de las nanofibras electrohiladas, la porosidad y el grosor de la capa retentiva de nanofibras poliméricas electrohiladas porosas se determinan como se define en la descripción, y el tamaño medio de poro se determina a partir de la medición del punto de burbuja de flujo medio de acuerdo con el procedimiento ASTM Designación E 1294-89, en donde el tamaño de poro de la capa de nanofibras porosas es menor que el tamaño de poro del lado estrecho de la membrana, en donde el tamaño de los poros se mide con la técnica del punto de burbuja de acuerdo con el procedimiento ASTM Designación E1294-89.

7. 发明专利

CA3116905A1 EFFICIENT PRODUCTION OF NANOFIBER STRUCTURES 未知
公开(公告)号：CA3116905A1
公开(公告)日：2020-05-07
申请号：CA3116905
申请日：2019-10-31
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , NGUYEN THANG , SATAV NITIN , CUDDY MARTIN
IPC分类号： D01D5/00 , D04H1/728
摘要： Provided herein are electrospinning apparatuses and methods for efficient production of nanofiber structures.

8. 发明专利

SG10201600617PA METHOD FOR RETROVIRUS REMOVAL 未知
公开(公告)号：SG10201600617PA
公开(公告)日：2016-11-29
申请号：SG10201600617P
申请日：2011-07-29
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , MOYA WILSON , GODDARD PHILIP , HAO JIBIN , SHERRY ASHBY LEON
摘要： A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.

9. 发明专利

SG185659A1 METHOD FOR RETROVIRUS REMOVAL 未知
公开(公告)号：SG185659A1
公开(公告)日：2012-12-28
申请号：SG2012085072
申请日：2011-07-29
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , MOYA WILSON , GODDARD PHILIP , LEON SHERRY , HAO JIBIN
摘要： A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism intention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.

10. 发明专利

SG10201707211WA NANOFIBER CONTAINING COMPOSITE STRUCTURES 未知
公开(公告)号：SG10201707211WA
公开(公告)日：2017-10-30
申请号：SG10201707211W
申请日：2012-07-23
申请人： EMD MILLIPORE CORP
发明人： KAS ONUR Y , KOZLOV MIKHAIL , TKACIK GABRIEL , NHIEM DAVID , GODDARD PHILIP , LEON SHERRY ASHBY
摘要： A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.

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