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1. 发明申请

WO2010099032A3 MITRAL VALVE REPLACEMENT WITH ATRIAL ANCHORING 审中-公开
标题翻译：麻醉阀更换与ATRIAL锚固
公开(公告)号：WO2010099032A3
公开(公告)日：2011-01-06
申请号：PCT/US2010024665
申请日：2010-02-19
申请人： EDWARDS LIFESCIENCES CORP , CHAU MARK , YI SEUNG , CORSO PHILLIP , POPP MICHAEL J , OLIN JANE , NGUYEN SON V , GOLEMO KEVIN
发明人： CHAU MARK , YI SEUNG , CORSO PHILLIP , POPP MICHAEL J , OLIN JANE , NGUYEN SON V , GOLEMO KEVIN
IPC分类号： A61F2/24 , A61F2/84 , A61F2/86 , A61L27/04 , A61L27/14 , A61M29/00
CPC分类号： A61F2/2457 , A61F2/2418 , A61F2/2436 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0039
摘要： A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly includes a stent and valve combination. The stent is designed so that the anchoring portion is positioned above the annulus of the mitral valve and in the left atrium. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place.
摘要翻译：公开了一种假体二尖瓣组件及其插入方法。在某些公开的实施例中，假体二尖瓣组件包括支架和瓣膜组合。支架被设计成使得锚固部分位于二尖瓣环和左心房的环上。支架是径向可扩张的，使得其能够相对于左心房的壁膨胀到适当的位置并适应宽范围的解剖结构。支架与左心房中的天然组织之间的接触减少了瓣膜渗漏，并防止了支架移动到位。

2. 发明申请

WO2011069048A2 PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 审中-公开
标题翻译：用于更换麻醉阀的前置阀
公开(公告)号：WO2011069048A2
公开(公告)日：2011-06-09
申请号：PCT/US2010058860
申请日：2010-12-03
申请人： EDWARD LIFESCIENCES CORP , CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61M25/01 , A61F2/24 , A61M25/02
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.
摘要翻译：提供了用于植入在天然二尖瓣内的人工瓣膜的实施例。假体阀的优选实施例包括可径向压缩的主体和单向阀部分。假体瓣膜还包括耦合到主体并设置在主体外部的至少一个心室锚。在主体的外表面和心室锚之间设置有用于接收原生二尖瓣小叶的空间。假体瓣膜优选地包括适于放置在二尖瓣环的上方的心房密封构件。还描述了用于输送和植入人工瓣膜的方法和装置。

3. 发明申请

WO2011069048A3 PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 审中-公开
标题翻译：用于更换二尖瓣的假体瓣膜
公开(公告)号：WO2011069048A3
公开(公告)日：2011-11-17
申请号：PCT/US2010058860
申请日：2010-12-03
申请人： EDWARD LIFESCIENCES CORP , CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61M25/01 , A61F2/24 , A61M25/02
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.
摘要翻译：提供了植入天然二尖瓣内的人工瓣膜的实施例。人造瓣膜的优选实施例包括可径向压缩的主体和单向阀部分。假体瓣膜进一步包括至少一个心室锚固件，所述至少一个心室锚定件联接到主体并设置在主体的外部。在主体的外表面和心室锚定器之间提供用于接收天然二尖瓣瓣叶的空间。假体瓣膜优选地包括适于放置在二尖瓣环的上方的心房密封构件。还描述了用于输送和植入假体瓣膜的方法和装置。

4. 发明专利

CA2966443A1 PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 未知
公开(公告)号：CA2966443A1
公开(公告)日：2011-06-09
申请号：CA2966443
申请日：2010-12-03
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61F2/24
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.

5. 发明专利

CA2966443C PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 未知
公开(公告)号：CA2966443C
公开(公告)日：2020-02-25
申请号：CA2966443
申请日：2010-12-03
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61F2/24
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.

6. 发明专利

ES2831253T3 Válvula protésica para reemplazar una válvula mitral 未知
公开(公告)号：ES2831253T3
公开(公告)日：2021-06-08
申请号：ES10835174
申请日：2010-12-03
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61M25/01 , A61F2/24 , A61M25/02
摘要： Válvula protésica (100) para su implantación en la región de válvula mitral nativa del corazón, presentando la válvula mitral nativa (2) un anillo (8) nativo y unas valvas de válvula nativa (10, 12), comprendiendo la válvula protésica: un cuerpo principal tubular (122) que comprende una luz y configurado para su colocación dentro del anillo (8) nativo, siendo el cuerpo principal radialmente compresible en un estado radialmente comprimido para su suministro dentro del corazón y autoexpansible desde el estado comprimido hasta un estado radialmente expandido; y una estructura de válvula (104) acoplada a la superficie interior del cuerpo principal, comprendiendo la estructura de válvula (104) una pluralidad de valvas de válvula (106) que forman una válvula unidireccional en la luz, estando la estructura de válvula suturada al cuerpo principal; caracterizada por al menos dos anclajes ventriculares (126) que se extienden desde un extremo ventricular (130) del cuerpo principal (122) y están dispuestos fuera del cuerpo principal para fijar la válvula protésica a las valvas de válvula mitral nativa (10, 12) anterior y posterior, estando los anclajes ventriculares (126) configurados para capturar las valvas de válvula mitral nativa (10, 12) entre los anclajes ventriculares (126) y una superficie exterior del cuerpo principal tubular (122); y un elemento de sellado auricular (124) que se extiende radialmente hacia el exterior desde un extremo auricular (132) del cuerpo principal (122), bloqueando el elemento de sellado auricular (124) la sangre que fluye más allá del extremo auricular (132) del cuerpo principal en el exterior del cuerpo principal cuando la válvula protésica (100) es implantada.

7. 发明专利

CA3064684A1 PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 未知
公开(公告)号：CA3064684A1
公开(公告)日：2011-06-09
申请号：CA3064684
申请日：2010-12-03
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61F2/24 , A61M25/01
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.

8. 发明公开

EP2485795A4 PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 有权
标题翻译： GRAFT DOOR TO更换二尖瓣
公开(公告)号：EP2485795A4
公开(公告)日：2014-07-09
申请号：EP10835174
申请日：2010-12-03
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , PATTERSON MARLOWE , YI SEUNG , GEIST STEVE , OBA TRAVIS
IPC分类号： A61M25/01 , A61F2/24 , A61M25/02
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor (126) coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.

9. 发明公开

EP2400926A4 MITRAL VALVE REPLACEMENT WITH ATRIAL ANCHORING 有权
标题翻译：锚二尖瓣房
公开(公告)号：EP2400926A4
公开(公告)日：2014-03-26
申请号：EP10746662
申请日：2010-02-19
申请人： EDWARDS LIFESCIENCES CORP
发明人： CHAU MARK , YI SEUNG , CORSO PHILLIP , POPP MICHAEL J , OLIN JANE , NGUYEN SON V , GOLEMO KEVIN
IPC分类号： A61F2/24 , A61F2/86 , A61F2/95 , A61L27/04 , A61L27/14 , A61M29/00
CPC分类号： A61F2/2457 , A61F2/2418 , A61F2/2436 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0039

10. 发明申请

WO2007123690A3 ARTICULABLE ANCHOR 审中-公开
标题翻译：物理锚
公开(公告)号：WO2007123690A3
公开(公告)日：2008-07-10
申请号：PCT/US2007007923
申请日：2007-03-30
申请人： SPIRATION INC , KUTSKO JAMES , YI SEUNG
发明人： KUTSKO JAMES , YI SEUNG
IPC分类号： A61F2/04 , A61F2/82
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12172 , A61F2/04 , A61F2/24 , A61F2002/043 , A61F2002/828 , A61F2220/0016 , A61F2220/0091 , A61F2230/0006 , A61F2310/00011
摘要： An implantable device (10) for providing one-way flow of air through a lumen in a human lung to reduce the volume of air trapped in a diseased portion of the lung by occluding the lumen to prevent inhalation while permitting expiration out of the diseased portion. The implantable device (10) is deployable in the lumen with a catheter. The device (10) comprises an umbrella-shaped, one-way valve (14). The valve (14) is collapsible for containment within a catheter and expandable in situ when deployed to occlude the lumen. The valve (14) defines a longitudinal axis and comprises a plurality of metal struts (30), a resilient membrane (32), and a central post (34). The device (10) further comprises an anchor (12) for securing the implantable device (10) within the lumen. The anchor (12) comprises a tapered distal end (24) for penetrating the wall of the lumen, and a planar member (26) positioned to limit advancement of the anchor (12) into the lumen. The implantable device (10) further comprises a mechanism (16) connecting the one-way valve (14) to the anchor (12). The mechanism (16) is disposed along the longitudinal axis when the device (10) is collapsed. The mechanism (16) is configured to permit the valve (14) to be oriented at an angle to said anchor (12) when deployed. Accordingly, the anchor (12) can be positioned in a section of the lumen that is at an angle to a section of said lumen in which said one-way valve (14) is positioned.
摘要翻译：一种用于提供空气通过人肺内腔的单向流动的可植入装置（10），以通过闭塞内腔来减少被困在肺部疾病部分中的空气的体积，以防止吸入，同时允许从疾病部分呼出。可植入装置（10）可用导管部署在内腔中。装置（10）包括伞形单向阀（14）。阀（14）可折叠以用于在导管内容纳并且在被部署以封闭内腔时可原位扩张。阀（14）限定纵向轴线并且包括多个金属支柱（30），弹性膜（32）和中心柱（34）。装置（10）还包括用于将可植入装置（10）固定在内腔内的锚固件（12）。锚固件（12）包括用于穿过内腔壁的锥形远端（24）和定位成限制锚固件（12）前进到内腔中的平面构件（26）。可植入装置（10）还包括将单向阀（14）连接到锚（12）的机构（16）。当装置（10）折叠时，机构（16）沿着纵向轴线设置。机构（16）构造成允许阀（14）在展开时以与所述锚固件（12）成一定角度定向。因此，锚定器（12）可以位于与所述单向阀（14）所在的所述内腔的一部分成一角度的内腔的一部分中。

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