专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100288022A1 NOVEL CHROMATOGRAPHY METHODS 审中-公开
标题翻译：新的色谱方法
公开(公告)号：US20100288022A1
公开(公告)日：2010-11-18
申请号：US12739754
申请日：2008-10-18
申请人： E.K.S. Vijaya Kumar , Amit Samel , Sachin Patil , Dilip Dhore
发明人： E.K.S. Vijaya Kumar , Amit Samel , Sachin Patil , Dilip Dhore
IPC分类号： G01N11/00 , G01N27/447
CPC分类号： G01N30/34 , G01N33/94
摘要： The present invention relates to novel HPLC methods for the analysis of the API formoterol and related substances. In a first method the mobile phase comprises two or more liquids, and the relative concentration of the liquids is varied to a predetermined gradient. In a second method the mobile phase comprises a first liquid A comprising an aqueous solution of ammonium acetate and a second liquid B comprising a dipolar aprotic solvent. In a third method the mobile phase comprises a first liquid A comprising an aqueous solution of ammonium acetate with a concentration of 0.001 to 0.025M, and a second liquid B. The present invention also relates to a method for analysing a substance, comprising the detection and optional quantification of one or more specific impurities.
摘要翻译：本发明涉及用于分析API福莫特罗和相关物质的新型HPLC方法。在第一种方法中，流动相包含两种或更多种液体，液体的相对浓度变化到预定的梯度。在第二种方法中，流动相包括包含乙酸铵水溶液的第一液体A和包含偶极非质子溶剂的第二液体B. 在第三种方法中，流动相包含第一液体A，其包含浓度为0.001至0.025M的乙酸铵水溶液和第二液体B.本发明还涉及用于分析物质的方法，包括检测并且可选地定量一种或多种特定杂质。

IPRDB

热门服务

关于我们

友情链接

联系方式