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1. 发明专利

JP2013047227A USE OF β-CRYPTOXANTHIN 审中-公开
标题翻译：使用＆bgr。-CRYPTOXANTHIN
公开(公告)号：JP2013047227A
公开(公告)日：2013-03-07
申请号：JP2012203513
申请日：2012-09-14
申请人： Dsm Ip Assets Bv , ディーエスエムアイピーアセッツビー.ブイ.
发明人： EICHINGER ANNE , GORALCZYK REGINA , WERTZ KARIN , WYSS ADRIAN
IPC分类号： A61K31/045 , A23K1/16 , A23K1/18 , A23L1/164 , A23L1/29 , A23L1/30 , A23L2/38 , A61K31/355 , A61K31/375 , A61P1/04 , A61P7/00 , A61P9/04 , A61P11/00 , A61P19/02 , A61P19/10 , A61P21/00 , A61P31/12 , A61P43/00
CPC分类号： A23L2/38 , A23L33/10 , A23L33/40 , A23V2002/00 , A23V2250/1612 , A23V2250/1642 , A23V2250/1592 , A23V2250/1588 , A23V2250/1584 , A23V2250/702 , A23V2250/704 , A23V2250/708 , A23V2250/71 , A23V2250/712 , A23V2250/1598 , A23V2250/161 , A23V2250/1626 , A23V2250/70 , A23V2250/641
摘要： PROBLEM TO BE SOLVED: To provide a composition for strengthening and increasing protein synthesis in tissue (in other words, liver, skin, kidney, muscle, and the like) of humans and animals in all conditions requiring or desiring an increase in protein formation within a living body, such as unsoundness conditions such as tumor cachexia and eating disorders (such as bulimia and anorexia), chronic diseases such as chronic cardiac failure, chronic obstructive pulmonary disease, chronic enteropathy (such as Crohn disease), and chronic degenerative disorders such as osteoporosis, rheumatoid arthritis, and osteoarthritis, and furthermore, in general, for promoting growth and development and promoting recovery in sports and training, as well as preventing and treating sarcopenia in aging.SOLUTION: A composition containing β-cryptoxanthin and esters thereof is used for promoting an increase in protein formation and/or preventing protein loss in humans and animals.
摘要翻译：待解决的问题：提供在需要或期望增加的所有条件下提供用于增强和增加人和动物组织（换句话说，肝，皮肤，肾，肌肉等）中的蛋白质合成的组合物生物体内的蛋白质形成，如肿瘤恶病质和进食障碍（如贪食症和厌食症）等不健康状况，慢性心脏衰竭，慢性阻塞性肺病，慢性肠病（如克罗恩病）等慢性疾病，慢性病退行性疾病如骨质疏松症，类风湿性关节炎和骨关节炎，此外，一般来说，用于促进生长发育和促进运动和训练的恢复，以及预防和治疗衰老的肌肉减少症。解决方案：含有β-隐黄质及其酯的组合物用于促进人和动物中蛋白质形成和/或预防蛋白质损失的增加。版权所有（C）2013，JPO＆INPIT

2. 发明专利

JP2013231056A Compound for improving body appearance and novel use of combination of the compound 审中-公开
标题翻译：用于改善身体外观和化合物组合的新型使用的化合物
公开(公告)号：JP2013231056A
公开(公告)日：2013-11-14
申请号：JP2013141672
申请日：2013-07-05
申请人： Dsm Ip Assets Bv , ディーエスエムアイピーアセッツビー.ブイ.
发明人： GORALCZYK REGINA , SCHWAGER JOSEPH , WERTZ KARIN
IPC分类号： A61K31/05 , A21D13/08 , A23C9/13 , A23F3/16 , A23L1/30 , A23L1/307 , A23L1/39 , A23L2/00 , A23L2/02 , A23L2/38 , A61K8/31 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/49 , A61K8/67 , A61K9/16 , A61K9/20 , A61K9/28 , A61K9/48 , A61K31/01 , A61K31/075 , A61K31/202 , A61K31/216 , A61K31/232 , A61K31/352 , A61K31/353 , A61P17/00 , A61P43/00 , A61Q19/06
CPC分类号： A61K8/31 , A21D2/36 , A23C9/13 , A23C9/1322 , A23L33/30 , A61K8/345 , A61K8/347 , A61K8/361 , A61K8/498 , A61K8/97 , A61K2800/92 , A61Q19/06
摘要： PROBLEM TO BE SOLVED: To provide a compound for treating cellulite, preventing generation of light cellulite, preventing progress of the light cellulite to heavy cellulite, smoothening fine rise and fall of skin, maintaining or increasing a firmness property of skin, and/or decreasing fat mass and surrounds in a gluteal and femoral region.SOLUTION: There is provided at least one kind of compound, selected from the group consisting of (-)-epigallocatechin gallate, resveratrol, eicosapentaenoic acid, docosahexaenoic acid, rosehip extract/condensate, hydroxytyrosol, lycopene, lutein, β-cryptoxanthin, zeaxanthin and a derivative thereof.
摘要翻译：要解决的问题：提供一种治疗脂肪团的化合物，防止轻质脂肪的产生，防止轻脂肪团进入重脂质团的进程，平滑皮肤的细小的上升和下降，保持或增加皮肤的坚实性，和/或降低提供了至少一种化合物，其选自（ - ） - 表没食子儿茶素没食子酸酯，白藜芦醇，二十碳五烯酸，二十二碳六烯酸，玫瑰果提取物/缩合物，羟基酪醇，番茄红素，叶黄素，黄曲霉素，玉米黄质及其衍生物。

3. 发明专利

JP2013236640A New use of organic compound 审中-公开
标题翻译：有机化合物的新用途
公开(公告)号：JP2013236640A
公开(公告)日：2013-11-28
申请号：JP2013143716
申请日：2013-07-09
申请人： Dsm Ip Assets Bv , ディーエスエムアイピーアセッツビー.ブイ.
发明人： GORALCZYK REGINA , WERTZ KARIN
IPC分类号： A23L1/30 , A23K1/16 , A23L2/52
CPC分类号： A61K8/34 , A23K20/111 , A23K20/174 , A23K20/179 , A23L2/58 , A23L7/126 , A23L33/105 , A23V2002/00 , A61K8/31 , A61K8/345 , A61K8/355 , A61K31/01 , A61K31/045 , A61K31/07 , A61K31/122 , A61Q19/08 , A23V2200/318 , A23V2250/211 , A23V2250/314 , A23V2250/712
摘要： PROBLEM TO BE SOLVED: To provide a composition which maintains the respiratory function of the skin, activates the skin, and prevents the variation of a UV-A irradiation-induced mtDNA from being caused so as to maintain energy metabolism, energy flow and/or energy production in the skin of animals including human beings.SOLUTION: A composition comprises a compound which is selected from the group consisting of β-carotene, lutein, lycopene, β-cryptoxanthin, a mixture thereof, and a combination of any of the compounds and CoQ-10, the composition concerned being orally applicable.
摘要翻译：要解决的问题：提供维持皮肤呼吸功能的组合物，激活皮肤，并且防止引起UV-A照射诱导的mtDNA的变化，从而保持能量代谢，能量流动和/或包括人在内的动物皮肤中的能量产生。解决方案：组合物包含选自以下的化合物：β-胡萝卜素，叶黄素，番茄红素，焦黄素，其混合物，以及任何化合物和CoQ-10，所述组合物是口服适用的。

4. 发明申请

WO2008006589A3 COMPOSITIONS COMPRISING ROSEHIP AND OTHER ACTIVE AGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS 审中-公开
标题翻译：包含用于治疗炎症性疾病的ROSEHIP和其他活性药剂的组合物
公开(公告)号：WO2008006589A3
公开(公告)日：2008-02-28
申请号：PCT/EP2007006201
申请日：2007-07-12
申请人： DSM IP ASSETS BV , RAEDERSTORFF DANIEL , SCHWAGER JOSEPH , WERTZ KARIN
发明人： RAEDERSTORFF DANIEL , SCHWAGER JOSEPH , WERTZ KARIN
IPC分类号： A61K36/738 , A61K31/365 , A61P19/02 , A61P29/00
CPC分类号： A61K36/484 , A23L33/105 , A23V2002/00 , A61K31/635 , A61K36/185 , A61K36/23 , A61K36/575 , A61K36/738 , A61K36/76 , A61K36/77 , A61K45/06 , A61K2300/00 , A23V2200/324 , A23V2250/21
摘要： The present invention relates to novel compositions comprising rosehip and at least one additional component e.g. selected from ligustilide, oleuropein (I), oleuropein aglycone (II), hydroxytyrosol, genistein, magnolol, honokiol, magnolia bark extract, cashew fruit extract and Glycyrrhiza foetida as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders.
摘要翻译：本发明涉及包含玫瑰果和至少一种另外的组分的新型组合物，例如选自ligustilide，oleuropein（I），oleuropein糖苷配基（II），羟基酪醇，染料木素，厚朴酚，厚朴酚，木兰树皮提取物，腰果提取物和甘草，以及这些组合物作为药物的用途，特别是作为用于治疗，共同治疗或预防炎症性疾病的药物。

5. 发明申请

WO2007131767A3 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA 审中-公开
标题翻译：对前瞻性癌症的新兴活动
公开(公告)号：WO2007131767A3
公开(公告)日：2008-04-03
申请号：PCT/EP2007004302
申请日：2007-05-15
申请人： DSM IP ASSETS BV , GORALCZYK REGINA , SILER ULRICH , WERTZ KARIN
发明人： GORALCZYK REGINA , SILER ULRICH , WERTZ KARIN
IPC分类号： A61K31/01 , A61K31/353 , A61K31/355 , A61P13/08 , A61P35/00
CPC分类号： A61K31/01 , A61K31/353 , A61K31/355 , A61K2300/00
摘要： The present invention relates to the use of a composition comprising lycopene and genistein in the prevention and coadjuvant treatment of prostate carcinoma. The present invention is also directed to the use of a composition comprising lycopene and epigallocatechin gallate in the prevention and coadjuvant treatment of prostate carcinoma. More specifically, the present invention relates to the use of one of these compositions in the primary prevention (i.e., the prophylactic supplementation of healthy subjects) of the onset of prostate carcinoma, in the coadjuvant treatment (i.e. the supplementation accompanying a running therapy of prostate carcinoma) and in the secondary prevention (i.e., the supplementation after a successful therapy for the prevention of relapse) of prostate carcinoma. Furthermore, the present invention is also directed to the reduction/decrease of the PSA plasma level in the blood of subjects to whom either a composition comprising lycopene and genistein or to whom either a composition comprising lycopene and epigallocatechin gallate are administered. Further compounds that may preferably also be present in the composition of the present invention are vitamin E, resveratrol and polyunsaturated fatty acid (derivative)s.
摘要翻译：本发明涉及包含番茄红素和染料木素的组合物在预防和辅助治疗前列腺癌中的用途。本发明还涉及包含番茄红素和表没食子儿茶素没食子酸酯的组合物在预防和辅助治疗前列腺癌中的用途。更具体地说，本发明涉及这些组合物中的一种在辅助治疗中的一级预防（即健康受试者的预防性补充）前列腺癌发作的用途（即伴随前列腺的运行治疗的补充）癌症）和前列腺癌的二次预防（即成功治疗预防复发后的补充）。此外，本发明还涉及给予包含番茄红素和染料木素的组合物或包含番茄红素和表没食子儿茶素没食子酸酯的组合物的受试者的血液中PSA血浆水平的降低/降低。还可以存在于本发明组合物中的其它化合物是维生素E，白藜芦醇和多不饱和脂肪酸（衍生物）。

6. 发明申请

WO2009144093A8 HYDROXYTYROSOL BENEFITS MITOCHONDRIA 审中-公开
标题翻译：羟喹诺酮益生菌
公开(公告)号：WO2009144093A8
公开(公告)日：2011-01-06
申请号：PCT/EP2009054585
申请日：2009-04-17
申请人： DSM IP ASSETS BV , LIU JIANKANG , RAEDERSTORFF DANIEL , WANG-SCHMIDT YING , WERTZ KARIN
发明人： LIU JIANKANG , RAEDERSTORFF DANIEL , WANG-SCHMIDT YING , WERTZ KARIN
IPC分类号： A61K31/05 , A23L1/00 , A61K36/63 , A61P1/16 , A61P7/00 , A61P9/00 , A61P21/00
CPC分类号： A61K31/05 , A61K36/63
摘要： Hydroxytyrosol or olive juice containing hydroxytyrosol can be used to maintain or increase mitochondrial biogenesis in cardiac muscle, skeletal muscles, and liver tissue.
摘要翻译：含有羟基酪醇的羟基酪醇或橄榄汁可用于维持或增加心肌，骨骼肌和肝组织中的线粒体生物发生。

7. 发明申请

WO2007112996A3 USE OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR IMPROVING THE PHYSICAL APPEARANCE 审中-公开
标题翻译：化合物的使用和化合物的组合用于改善物理外观
公开(公告)号：WO2007112996A3
公开(公告)日：2010-07-08
申请号：PCT/EP2007002950
申请日：2007-04-02
申请人： DSM IP ASSETS BV , GORALCZYK REGINA , SCHWAGER JOSEPH , WERTZ KARIN
发明人： GORALCZYK REGINA , SCHWAGER JOSEPH , WERTZ KARIN
IPC分类号： A61Q19/06 , A61K8/31 , A61K8/34 , A61K8/36 , A61K8/97 , A61Q19/08
CPC分类号： A61K8/31 , A21D2/36 , A23C9/13 , A23C9/1322 , A23L33/30 , A61K8/345 , A61K8/347 , A61K8/361 , A61K8/498 , A61K8/97 , A61K2800/92 , A61Q19/06
摘要： The present invention is directed inter alia to the use of at least one compound selected from the group consisting of (-)-epigallocatechin gallate, resveratrol, eicosapentaenoic acid, docosahexaenoic acid, rose hip extract/concentrate, hydroxytyrosol, lycopene, lutein, ß-cryptoxanthin, zeaxanthin and derivatives thereof, for the treatment of cellulite, for the prevention of the development of mild cellulite, for the prevention of the progression of mild cellulite to severe cellulite, for smoothening the micro relief of the skin, for maintaining or increasing the tensile properties of the skin, and/or for reducing the fat mass and the circumference at the hips and thighs, as well as to the corresponding cosmetic and medical methods.
摘要翻译：本发明尤其涉及使用至少一种选自（ - ） - 表没食子儿茶素没食子酸酯，白藜芦醇，二十碳五烯酸，二十二碳六烯酸，玫瑰果提取物/浓缩物，羟基酪醇，番茄红素，叶黄素，β- 隐黄质，玉米黄质及其衍生物，用于治疗脂肪团，用于防止轻度脂肪团的发育，用于防止轻度脂肪团进入严重脂肪团的进展，以平滑皮肤的微小浮雕，维持或增加皮肤的拉伸性能和/或用于降低臀部和大腿处的脂肪量和周长，以及相应的美容和医疗方法。

8. 发明申请

WO2007134867A2 NOVEL USE OF ORGANIC COMPOUNDS 审中-公开
标题翻译：有机化合物的新用途
公开(公告)号：WO2007134867A2
公开(公告)日：2007-11-29
申请号：PCT/EP2007004627
申请日：2007-05-24
申请人： DSM IP ASSETS BV , D ORAZIO DANIEL , RAEDERSTORFF DANIEL , SCHUELER GOEDE , WANG-SCHMIDT YING , WERTZ KARIN , WOLFRAM SWEN
发明人： D ORAZIO DANIEL , RAEDERSTORFF DANIEL , SCHUELER GOEDE , WANG-SCHMIDT YING , WERTZ KARIN , WOLFRAM SWEN
IPC分类号： A61P21/00 , A23L1/30 , A61K31/12 , A61K31/166 , A61K31/352 , A61P1/00 , A61P9/00 , A61P9/10 , A61P19/02
CPC分类号： A23K20/111 , A23L2/52 , A23L33/10 , A23V2002/00 , A61K31/12 , A61K31/166 , A61K31/352 , A23V2200/316 , A23V2200/328 , A23V2200/326 , A23V2200/318 , A23V2200/32
摘要： The present invention refers to compounds of the general formulae Ia to Ie as defined above for use as/in a composition (especially foods and dietary supplements, cosmetic, as well as pharmaceutical compositions) for the prevention and improvement of muscular disorders and for the improvement of muscle function. Other fields of use are disorders connected to impaired lipid metabolism, impaired glucose metabolism and impaired insulin action, obesity, overweight conditions, eating disorders such as bulimia and anorexia nervosa, cardiovascular diseases, atherosclerosis, vascular diseases, heart failure, inflammatory disorders such as arthritis, rheumatoid arthritis, osteoarthritis, gout, gastrointestinal disorders such as inflammatory bowel syndrome, Crohn's disease, gastritis, irritable bowel syndrome and ulcerative colitis, skin related conditions such as psoriasis, eczema, burns, dermatitis, and allergy,, respiratory disorders such as asthma, chronic obstructive pulmonary disease (COPD), allergic diseases, and/or bone disorders such as osteoporosis and osteopenia. The compounds may also be used for bodyshaping, for improving the muscle : fat ratio or for accelerating skin wound healing. The present invention is also directed to dietary compositions such as (fortified) food, beverages, (fortified) feed, food additives, beverage additives, feed additives, clinical nutrition, dietary supplements, functional food, functional feed and nutraceuticals and to pharmaceutical compositions containing such compounds, to methods of treating the above mentioned disorders/diseases in mammals including humans and to the compounds of the formula I themselves. Another object of the present invention is the use of such compounds for the manufacture of a composition for the treatment of such disorders/diseases as mentioned above.
摘要翻译：本发明涉及如上定义的用于预防和改善肌肉疾病和改善的组合物（特别是食品和膳食补充剂，化妆品以及药物组合物）中的上述通式Ia至Ie的化合物的肌肉功能。其他使用领域是与脂质代谢受损，葡萄糖代谢受损和胰岛素作用受损，肥胖症，超重症状，进食障碍如贪食症和神经性厌食症，心血管疾病，动脉粥样硬化，血管疾病，心力衰竭，炎症性疾病如关节炎相关的疾病，类风湿性关节炎，骨关节炎，痛风，胃肠道疾病如肠炎综合征，克罗恩病，胃炎，肠易激综合征和溃疡性结肠炎，皮肤相关病症如牛皮癣，湿疹，烧伤，皮炎和过敏，呼吸系统疾病如哮喘，慢性阻塞性肺疾病（COPD），过敏性疾病和/或骨骼疾病如骨质疏松症和骨质减少。这些化合物也可用于体脂整形，用于改善肌肉：脂肪比例或用于加速皮肤伤口愈合。本发明还涉及饮食组合物，例如（强化）食品，饮料，（强化）饲料，食品添加剂，饮料添加剂，饲料添加剂，临床营养，膳食补充剂，功能性食品，功能性饲料和营养食品，以及含有这些化合物，涉及治疗哺乳动物（包括人）和式I本身化合物的上述疾病/疾病的方法。本发明的另一个目的是使用这些化合物来制备用于治疗如上所述的这种疾病/疾病的组合物。

9. 发明公开

EP2501371A4 USE OF HYDROXYTYROSOL FOR IMPROVING MUSCLE DIFFERENTIATION 审中-公开
标题翻译：羟基酪醇用于改进肌肉分化USE
公开(公告)号：EP2501371A4
公开(公告)日：2013-07-31
申请号：EP10821546
申请日：2010-10-08
申请人： DSM IP ASSETS BV
发明人： LIU JIANKANG , WANG-SCHMIDT YING , WERTZ KARIN , FENG ZHIHUI
IPC分类号： A61K31/05 , A23L1/30 , A23L2/52 , A61K36/63 , A61P21/02
CPC分类号： A61K31/05 , A23L2/52 , A23L33/105 , A61K36/63

10. 发明专利

ES2351701T3 USO DE ß-CRIPTOXANTINA. 未知
公开(公告)号：ES2351701T3
公开(公告)日：2011-02-09
申请号：ES05738192
申请日：2005-05-10
申请人： DSM IP ASSETS BV
发明人： WERTZ KARIN , GORALCZYK REGINA , WYSS ADRIAN , EICHINGER ANNE
IPC分类号： A23L1/30 , A23K1/16 , A23L1/164 , A23L2/38 , A23L33/00 , A23L33/155
摘要： El uso no terapéutico de β-criptoxantina para promover una formación incrementada de proteína en un ser humano o un animal.

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