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1. 发明申请

US20110046042A1 Long Interspersed Nuclear Element Polypeptide Compositions and Methods of Use Thereof 审中-公开
标题翻译：长散布的核元素多肽组合物及其使用方法
公开(公告)号：US20110046042A1
公开(公告)日：2011-02-24
申请号：US12677278
申请日：2008-09-19
申请人： Douglas F. Nixon , Keith Garrison , Duncan Meiklejohn , Mario Ostrowski , R. Bradley Jones , Ashish Agrawal , Frederick M. Hecht
发明人： Douglas F. Nixon , Keith Garrison , Duncan Meiklejohn , Mario Ostrowski , R. Bradley Jones , Ashish Agrawal , Frederick M. Hecht
IPC分类号： A61K38/08 , C07K7/06 , C07H21/04 , C07K7/08 , A61P31/18 , C12N15/63 , A61K31/7088 , A61K38/10 , C12Q1/02 , A61P35/00 , A61P31/12
CPC分类号： C07K14/47 , A61K39/0005 , A61K39/0011 , A61K2039/53 , A61K2039/55 , A61K2039/57 , C12N2740/16011 , G01N33/5047 , G01N2333/15 , G01N2333/52
摘要： The present invention provides LINE polypeptides; and compositions, including immunogenic compositions, comprising a subject LINE polypeptide. The present invention provides a recombinant nucleic acid comprising a nucleotide sequence encoding a subject LINE polypeptide. A subject composition is useful for stimulating a T-cell immune response to a LINE peptide. The present invention further provides methods of stimulating an immune response in an individual to a retrovirus- or lentivirus-infected cell. The present invention further provides methods of treating cancers that are associated with tissues in which LINE polypeptides are aberrantly expressed. Also provided are methods of treating disorders, involving decreasing an immune response to a LINE polypeptide.
摘要翻译：本发明提供LINE多肽; 和包含免疫原性组合物的组合物，其包含受试者LINE多肽。本发明提供了包含编码受试者LINE多肽的核苷酸序列的重组核酸。主题组合物可用于刺激对LINE肽的T细胞免疫应答。本发明还提供刺激个体对逆转录病毒或慢病毒感染细胞的免疫应答的方法。本发明还提供了治疗与LINE多肽异常表达的组织相关的癌症的方法。还提供了治疗疾病的方法，涉及降低对LINE多肽的免疫应答。

2. 发明申请

US20080171061A1 Human endogenous retrovirus polypeptide compositions and methods of use thereof 审中-公开
标题翻译：人内源性逆转录病毒多肽组合物及其使用方法
公开(公告)号：US20080171061A1
公开(公告)日：2008-07-17
申请号：US11880126
申请日：2007-07-19
申请人： Douglas Nixon , Keith Garrison , Duncan Meiklejohn , Mario Ostrowski , R. Bradley Jones , Ashish Agrawal , Jack Lenz , Seth Rakoff-Nahoum , Frederick M. Hecht
发明人： Douglas Nixon , Keith Garrison , Duncan Meiklejohn , Mario Ostrowski , R. Bradley Jones , Ashish Agrawal , Jack Lenz , Seth Rakoff-Nahoum , Frederick M. Hecht
IPC分类号： A61K39/21 , A61K31/70 , C07K16/00 , C12N5/00
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/54 , A61K2039/55505 , A61K2039/55566 , A61K2039/55572 , A61K2039/55583 , C12N2740/16034
摘要： The present invention provides isolated HERV polypeptides; and compositions, including immunogenic compositions, comprising a HERV polypeptide. The present invention provides immunogenic compositions comprising a nucleic acid comprising a nucleotide sequence encoding a HERV polypeptide. The immunogenic compositions are useful for stimulating a T cell immune response to a lentiviral peptide. The present invention further provides methods of stimulating an immune response in an individual to a retrovirus- or lentivirus-infected cell. The present invention further provides methods of treating cancers in which HERV polypeptides are expressed. Also provided are methods of treating disorders, involving decreasing an immune response to a HERV polypeptide.
摘要翻译：本发明提供了分离的HERV多肽; 和包含HERV多肽的组合物，包括免疫原性组合物。本发明提供了包含含有编码HERV多肽的核苷酸序列的核酸的免疫原性组合物。免疫原性组合物可用于刺激对慢病毒肽的T细胞免疫应答。本发明还提供刺激个体对逆转录病毒或慢病毒感染细胞的免疫应答的方法。本发明还提供了治疗其中表达HERV多肽的癌症的方法。还提供了治疗疾病的方法，涉及降低对HERV多肽的免疫应答。

3. 发明申请

US20210202378A1 TOP GATE RECESSED CHANNEL CMOS THIN FILM TRANSISTOR IN THE BACK END OF LINE AND METHODS OF FABRICATION 有权
公开(公告)号：US20210202378A1
公开(公告)日：2021-07-01
申请号：US16728887
申请日：2019-12-27
申请人： Gilbert Dewey , Ryan Keech , Cory Bomberger , Cheng-Ying Huang , Ashish Agrawal , Willy Rachmady , Anand Murthy
发明人： Gilbert Dewey , Ryan Keech , Cory Bomberger , Cheng-Ying Huang , Ashish Agrawal , Willy Rachmady , Anand Murthy
IPC分类号： H01L23/522 , H01L27/12 , H01L21/762 , H01L21/768
摘要： A device includes a device level having a metallization structure coupled to a semiconductor device and a transistor above the device level. The transistor has a body including a single crystal group III-V or group IV semiconductor material, a source structure on a first portion of the body and a drain structure on a second portion of the body, where the source structure is separate from the drain structure. The transistor further includes a gate structure including a first gate structure portion in a recess in the body and a second gate structure portion between the source structure and the drain structure. A source contact is coupled with the source structure and a drain contact is coupled with the drain structure. The source contact is in contact with the metallization structure in the device level.

4. 发明授权

US09189811B1 Electronic marketplace recommendations 有权
标题翻译：电子市场推荐
公开(公告)号：US09189811B1
公开(公告)日：2015-11-17
申请号：US12683548
申请日：2010-01-07
申请人： Amit Bhosle , Ashish Agrawal
发明人： Amit Bhosle , Ashish Agrawal
IPC分类号： G06Q30/00 , G06F17/30 , G06Q30/06
CPC分类号： G06Q30/0631 , G06Q30/06 , G06Q30/0601 , G06Q30/0603 , G06Q30/0641
摘要： A shared “universal” virtual shopping cart (“the cart”) may be provided by a host to enable information sharing between multiple disparate electronic marketplaces provided by various merchants. The host may obtain user information via the cart to improve interactions with a user. The host may recommend an item to the user that is offered at a lower price and related to an item retained in the user's cart. The host may also recommend items based on a user's purchase history, such as complementary items (e.g., up-sell items) and items other users may recommend. In some aspects, the host may compile best selling lists based on data from multiple electronic marketplaces. The host may also perform user specific operations such as indicate an item in a cart is a duplicate of a previous purchase and monitor a price and/or available quantities of an item in the cart.
摘要翻译：可以由主机提供共享的“通用”虚拟购物车（“购物车”），以实现由各种商家提供的多个不同的电子市场之间的信息共享。主机可以通过购物车获得用户信息，以改善与用户的交互。主持人可以向用户推荐以较低价格提供并与用户购物车中保留的物品相关的用户的物品。主持人还可以基于用户的购买历史来推荐商品，例如补充商品（例如，上销商品）和其他用户可能推荐的商品。在某些方面，主机可以根据来自多个电子市场的数据编制最佳销售列表。主机还可以执行用户特定的操作，例如指示购物车中的商品与先前购买的重复，并监视购物车中的商品的价格和/或可用数量。

5. 发明授权

US09037963B1 Secure cross-domain web browser communications 有权
标题翻译：安全的跨域网页浏览器通信
公开(公告)号：US09037963B1
公开(公告)日：2015-05-19
申请号：US13092695
申请日：2011-04-22
申请人： Hendi Chandi , Ashish Agrawal , Dhanvi H. Kapila , Vineesh Sinha
发明人： Hendi Chandi , Ashish Agrawal , Dhanvi H. Kapila , Vineesh Sinha
IPC分类号： G06F17/00 , G06F17/30
CPC分类号： G06Q30/0641 , G06F17/00 , G06F17/30861 , G06F17/30864 , G06F21/00 , G06Q20/12 , G06Q30/0253 , H04L63/00 , H04L67/02 , H04L67/10 , H04L67/38
摘要： Methods, systems and computer program products are provided in which a first “sender” web browser window that is within a first domain can communicate with a second “target” web browser window that is within a second, different domain. Pursuant to these techniques, an iframe may be provided within the target web browser window that has a source address that is within the first domain. The content of the iframe may be a function that forwards a received message to the target web browser window. The target web browser window may receive a message in response to the sender web browser window invoking the function of the iframe.
摘要翻译：提供了方法，系统和计算机程序产品，其中在第一域内的第一“发送者”web浏览器窗口可以与位于第二不同域内的第二“目标”web浏览器窗口进行通信。根据这些技术，可以在具有在第一域内的源地址的目标web浏览器窗口内提供iframe。 iframe的内容可能是将接收到的消息转发到目标Web浏览器窗口的功能。目标Web浏览器窗口可以响应于发送者web浏览器窗口调用iframe的功能而接收消息。

6. 发明申请

US20120247933A1 SWITCHGEAR ASSEMBLY 有权
标题翻译：开关总成
公开(公告)号：US20120247933A1
公开(公告)日：2012-10-04
申请号：US13432981
申请日：2012-03-28
申请人： Deepak Raorane , Ashish Agrawal
发明人： Deepak Raorane , Ashish Agrawal
IPC分类号： H01H9/16
CPC分类号： H02B1/306 , H01H1/0015 , H01H2009/0292 , H02B13/045
摘要： A switchgear assembly includes a tank housing encapsulating switching contacts which are viewable through a transparent viewing port after illumination of the contacts. A reflective optical device for observing the position of the switching contacts is used to view the contacts at a safe distance outside of the tank housing through the transparent viewing port. An illuminating device is used to illuminate the switching contacts by directing the light from the illuminating device on the switch contacts.
摘要翻译：开关组件包括容纳开关触点的容器壳体，所述开关触点在触点的照射之后可透过透明观察口观察。用于观察开关触点的位置的反射光学装置用于通过透明观察端口在罐壳体外部的安全距离处观察触点。照明装置用于通过将来自照明装置的光引导到开关触点上来照亮开关触点。

7. 发明授权

US08019653B1 Providing composite services based on multiple other constituent services 有权
标题翻译：提供基于多个其他组成服务的复合服务
公开(公告)号：US08019653B1
公开(公告)日：2011-09-13
申请号：US12709340
申请日：2010-02-19
申请人： Robert Frederick , Gunavardhan Kakulapati , Ashish Agrawal , James R. McCann, III
发明人： Robert Frederick , Gunavardhan Kakulapati , Ashish Agrawal , James R. McCann, III
IPC分类号： G06Q30/00 , G06F15/00 , G06F15/16
CPC分类号： G06Q30/06 , G06Q30/0601
摘要： Techniques are described for assisting users in dynamically creating and using composite services that are based on other constituent services. In some situations, each constituent service is a Web service (“WS”), and each composite service is a new WS whose execution involves dynamically invoking multiple specified constituent WSes in a specified manner. Such techniques may be used, for example, in conjunction with an electronic WS marketplace via which third-party WS providers make their WSes available to third-party WS consumers who locate and purchase access to those WSes, such as to allow a user to dynamically create a new composite WS that is based on one or more WSes available from other WS providers and that reflects any constraints of the WS marketplace, with the composite WS available for use by other WS consumers. This abstract is not intended for use in interpreting or limiting the scope of the claims.
摘要翻译：描述了帮助用户动态创建和使用基于其他构成服务的复合服务的技术。在某些情况下，每个组件服务是一个Web服务（“WS”），每个组合服务是一个新的WS，其执行涉及以指定的方式动态地调用多个指定的组件WSes。这样的技术可以例如与电子WS市场结合使用，第三方WS提供商通过该电子WS市场将其WSes可用于定位和购买对这些WSes的访问的第三方WS消费者，例如允许用户动态创建一个基于一个或多个可从其他WS提供者获得的WSes并且反映WS市场的任何限制的新的复合WS，其中复合WS可供其他WS消费者使用。本摘要不旨在用于解释或限制权利要求的范围。

8. 发明授权

US07912764B1 Generating new composite network services based on user selection of other constituent network services 有权
标题翻译：基于用户选择其他组成网络服务生成新的复合网络服务
公开(公告)号：US07912764B1
公开(公告)日：2011-03-22
申请号：US12704438
申请日：2010-02-11
申请人： Robert Frederick , Gunavardhan Kakulapati , Ashish Agrawal , James R. McCann, III
发明人： Robert Frederick , Gunavardhan Kakulapati , Ashish Agrawal , James R. McCann, III
IPC分类号： G06F17/30 , G06F15/00
CPC分类号： G06F9/465 , G06F2209/462 , G06Q30/0601 , G06Q30/0621 , G06Q30/0641
摘要： Techniques are described for assisting users in dynamically creating and using composite services that are based on other constituent services. In some situations, each constituent service is a Web service (“WS”), and each composite service is a new WS whose execution involves dynamically invoking multiple specified constituent WSes in a specified manner. Such techniques may be used, for example, in conjunction with an electronic WS marketplace via which third-party WS providers make their WSes available to third-party WS consumers who locate and purchase access to those WSes, such as to allow a user to dynamically create a new composite WS that is based on one or more WSes available from other WS providers and that reflects any constraints of the WS marketplace, with the composite WS available for use by other WS consumers. This abstract is not intended for use in interpreting or limiting the scope of the claims.
摘要翻译：描述了帮助用户动态创建和使用基于其他构成服务的复合服务的技术。在某些情况下，每个组件服务是一个Web服务（“WS”），每个组合服务是一个新的WS，其执行涉及以指定的方式动态地调用多个指定的组件WSes。这样的技术可以例如与电子WS市场结合使用，第三方WS提供商通过该电子WS市场将其WSes可用于定位和购买对这些WSes的访问的第三方WS消费者，例如允许用户动态创建一个基于一个或多个可从其他WS提供者获得的WSes并且反映WS市场的任何限制的新的复合WS，其中复合WS可供其他WS消费者使用。本摘要不旨在用于解释或限制权利要求的范围。

9. 发明申请

US20090144172A1 PROVIDING A MARKETPLACE FOR WEB SERVICES 有权
标题翻译：提供WEB服务的市场
公开(公告)号：US20090144172A1
公开(公告)日：2009-06-04
申请号：US12366536
申请日：2009-02-05
申请人： Robert Frederick , Ashish Agrawal , Jeffrey Barr
发明人： Robert Frederick , Ashish Agrawal , Jeffrey Barr
IPC分类号： G06Q30/00
CPC分类号： G06Q30/06 , G06Q20/102 , G06Q30/0283 , G06Q30/0601 , G06Q30/0611 , G06Q30/0613
摘要： A method, system, and computer-readable medium is described for facilitating interactions between computing systems, such as by providing an electronic Web service (“WS”) marketplace via which third-party WS providers make their WSes available to third-party WS consumers who locate and purchase access to those WSes via the electronic marketplace. Some or all available WSes may have associated use prices and or non-price use conditions, and if so access to those WSes may be provided only if a consumer requesting access provides appropriate payment and otherwise satisfies the specified use conditions. In some situations, WS consumers may also purchase subscriptions to provide later access to registered WSes. This abstract is provided to comply with rules requiring it, and is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述了用于促进计算系统之间的交互的方法，系统和计算机可读介质，例如通过提供电子Web服务（“WS”）市场，第三方WS提供商通过该电子Web服务提供商使其WSes可用于第三方WS消费者谁通过电子市场找到并购买对这些WSes的访问。一些或所有可用的WSes可能具有相关联的使用价格和/或非价格使用条件，并且如果这样，只有当请求访问的消费者提供适当的支付并且满足指定的使用条件时，才可以提供对这些WSes的访问。在某些情况下，WS消费者也可能会购买订阅，以便稍后访问注册的WSes。提供本摘要以符合要求它的规则，并提交，意图是不会用于解释或限制权利要求的范围或含义。

10. 发明申请

US20050165656A1 Providing a marketplace for web services 有权
标题翻译：提供Web服务的市场
公开(公告)号：US20050165656A1
公开(公告)日：2005-07-28
申请号：US10766697
申请日：2004-01-27
申请人： Robert Frederick , Ashish Agrawal , Jeffrey Barr
发明人： Robert Frederick , Ashish Agrawal , Jeffrey Barr
IPC分类号： G06Q30/00 , G06F17/60
CPC分类号： G06Q30/06 , G06Q20/102 , G06Q30/0283 , G06Q30/0601 , G06Q30/0611 , G06Q30/0613
摘要： A method, system, and computer-readable medium is described for facilitating interactions between computing systems, such as by providing an electronic Web service (“WS”) marketplace via which third-party WS providers make their WSes available to third-party WS consumers who locate and purchase access to those WSes via the electronic marketplace. Some or all available WSes may have associated use prices and or non-price use conditions, and if so access to those WSes may be provided only if a consumer requesting access provides appropriate payment and otherwise satisfies the specified use conditions. In some situations, WS consumers may also purchase subscriptions to provide later access to registered WSes. This abstract is provided to comply with rules requiring it, and is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：描述了一种方法，系统和计算机可读介质，用于促进计算系统之间的交互，例如通过提供电子Web服务（“WS”）市场，第三方WS提供商通过该电子Web服务提供商使其WSes可用于第三方WS消费者谁通过电子市场找到并购买对这些WSes的访问。一些或所有可用的WSes可能具有相关联的使用价格和/或非价格使用条件，并且如果这样，只有当请求访问的消费者提供适当的支付并且满足指定的使用条件时，才可以提供对这些WSes的访问。在某些情况下，WS消费者也可能会购买订阅，以便稍后访问注册的WSes。提供本摘要以符合要求它的规则，并提交，意图是不会用于解释或限制权利要求的范围或含义。

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