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1. 发明授权

US06265636B1 Pyruvate dehydrogenase kinase polynucleotides, polypeptides and uses thereof 有权
标题翻译：丙酮酸脱氢酶激酶多核苷酸，多肽及其用途
公开(公告)号：US06265636B1
公开(公告)日：2001-07-24
申请号：US09333423
申请日：1999-06-15
申请人： Douglas D. Randall , Jay J. Thelen , Jan A. Miernyk , Michael G. Muszynski , Vincent J. H. Sewalt
发明人： Douglas D. Randall , Jay J. Thelen , Jan A. Miernyk , Michael G. Muszynski , Vincent J. H. Sewalt
IPC分类号： C12N504
CPC分类号： C12N9/1205 , C12N15/8243 , C12N15/8247
摘要： The invention provides methods and compositions relating to altering carbohydrate metabolism and/or composition of plants. The invention provides isolated nucleic acids and their encoded proteins, expression cassettes, host cells, transgenic plants, and antibody compositions.
摘要翻译：本发明提供了与改变植物的碳水化合物代谢和/或组成有关的方法和组合物。本发明提供分离的核酸及其编码的蛋白质，表达盒，宿主细胞，转基因植物和抗体组合物。

2. 发明授权

US08835361B2 High-throughput quantitation of crop seed proteins 有权
标题翻译：作物种子蛋白的高通量定量
公开(公告)号：US08835361B2
公开(公告)日：2014-09-16
申请号：US13149716
申请日：2011-05-31
申请人： Jay J. Thelen , Severin E. Stevenson
发明人： Jay J. Thelen , Severin E. Stevenson
IPC分类号： C40B30/10 , A61K38/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K14/00 , C07K16/00 , C07K17/00 , G01N33/68
CPC分类号： G01N33/6848
摘要： The invention provides a high-throughput method for quantitating plant seed proteins, e.g. seed allergens. Such method involves obtaining a protein sample from the seed; analyzing the sample using mass spectrometry with a set of pre-designed internal standard peptides that are specific to the plant allergens; and monitoring frequencies and intensities of resulting spectra to obtain relative and absolute allergen contents in the seed. The invention also provides a system for high-throughput profiling of plant seed allergens. Such system comprises a set of pre-designed internal standard peptides that are specific to the plant seed allergens and one or more mass spectrometers.
摘要翻译：本发明提供了用于定量植物种子蛋白质的高通量方法，例如，种子过敏原。这种方法包括从种子获得蛋白质样品; 使用一组预先设计的对植物变应原特异的内标肽进行质谱分析样品; 并监测所得光谱的频率和强度，以获得种子中相对和绝对的变应原含量。本发明还提供了用于植物种子过敏原的高通量分析的系统。这种系统包括一组预先设计的对植物种子过敏原和一种或多种质谱仪特异的内标肽。

3. 发明申请

US20110294700A1 HIGH-THROUGHPUT QUANTITATION OF CROP SEED PROTEINS 有权
标题翻译：作物种子蛋白的高通量定量
公开(公告)号：US20110294700A1
公开(公告)日：2011-12-01
申请号：US13149716
申请日：2011-05-31
申请人： Jay J. Thelen , Severin E. Stevenson
发明人： Jay J. Thelen , Severin E. Stevenson
IPC分类号： C40B30/10 , C40B60/12
CPC分类号： G01N33/6848
摘要： The invention provides a high-throughput method for quantitating plant seed proteins, e.g. seed allergens. Such method involves obtaining a protein sample from the seed; analyzing the sample using mass spectrometry with a set of pre-designed internal standard peptides that are specific to the plant allergens; and monitoring frequencies and intensities of resulting spectra to obtain relative and absolute allergen contents in the seed. The invention also provides a system for high-throughput profiling of plant seed allergens. Such system comprises a set of pre-designed internal standard peptides that are specific to the plant seed allergens and one or more mass spectrometers.
摘要翻译：本发明提供了用于定量植物种子蛋白质的高通量方法，例如，种子过敏原。这种方法包括从种子获得蛋白质样品; 使用一组预先设计的对植物变应原特异的内标肽进行质谱分析样品; 并监测所得光谱的频率和强度，以获得种子中相对和绝对的变应原含量。本发明还提供了用于植物种子过敏原的高通量分析的系统。这种系统包括一组预先设计的对植物种子过敏原和一种或多种质谱仪特异的内标肽。

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