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1. 发明申请

US20090053818A1 Quantitative proteomics with isotopic substituted raman active labeling 审中-公开
标题翻译：定量蛋白质组学与同位素取代拉曼活性标记
公开(公告)号：US20090053818A1
公开(公告)日：2009-02-26
申请号：US11663862
申请日：2005-09-26
申请人： Dongmao Zhang , Jo V. Davisson , Dor Ben-Amotz , Yong Xie , Kumar Shirshendu Deb
发明人： Dongmao Zhang , Jo V. Davisson , Dor Ben-Amotz , Yong Xie , Kumar Shirshendu Deb
IPC分类号： G01N33/68 , C07D311/82 , G01N33/50
CPC分类号： G01N33/54373 , Y10T436/143333
摘要： A labeling reagent having a distinct Raman, or surface enhanced Raman, spectral signature is used for the control and analysis samples. The labeling reagents can be fluorescent dyes with different isotopic substituents, such as the substitution of some hydrogen atoms for deuterium atoms. Such labeling does not have any detectable effect on separation retention. Raman spectroscopy is used for detection purposes. By combining SERS and SERRS, a concentration ratio prediction error of less than 3% can be obtained over four orders of magnitude of total concentration with up to a factor of 3 concentration ratio range. The method is reliable, reproducible and more sensitive than methods based on absolute SERS/SERRS intensity correlations, with no internal standard, or using a different molecule (rather than an IEIS) as a SERS/SERRS internal standard.
摘要翻译：具有不同拉曼或表面增强拉曼光谱特征的标记试剂用于对照和分析样品。标记试剂可以是具有不同同位素取代基的荧光染料，例如用一些氢原子取代氘原子。这种标记对分离保留没有任何可检测的影响。拉曼光谱用于检测目的。通过组合SERS和SERRS，可以获得总浓度四个数量级以上的浓度比预测误差小于3％，达到3倍浓度比范围。该方法比基于绝对SERS / SERRS强度相关性无内标或使用不同分子（而不是IEIS）作为SERS / SERRS内标的方法可靠，可重现和更灵敏。

2. 发明授权

US07283228B2 Process and apparatus for segregation and testing by spectral analysis of solid deposits derived from liquid mixtures 有权
标题翻译：通过对来自液体混合物的固体沉积物的光谱分析进行分离和测试的方法和装置
公开(公告)号：US07283228B2
公开(公告)日：2007-10-16
申请号：US10821231
申请日：2004-04-08
申请人： Dongmao Zhang , Dor Ben-Amotz , Yong Xie , Vincent J. Davisson , Melissa Mrozek , Corasi Ortiz
发明人： Dongmao Zhang , Dor Ben-Amotz , Yong Xie , Vincent J. Davisson , Melissa Mrozek , Corasi Ortiz
IPC分类号： G01J3/44 , G01N21/65 , G01N1/00
CPC分类号： G01N21/3563 , B82Y30/00 , G01N21/658 , G01N2001/4027 , G01N2021/3595
摘要： Micro-droplets of liquid confining organic molecules of interest are dried on selected planar solvo-phobic substrates under conditions facilitating segregated precipitation of the larger, less soluable analytes toward edge portions of the deposit. Micro-spectrometer imaging using white light and FTIR false color can identify points of interest, and the same optics generally directed perpendicularly to the substrates selectively captures normal Raman spectra from selected points in the deposit. The spectra are manipulated using various data techniques to extract reliable information concerning analytes present at pico-Molar levels. The selected spots can also be subjected to FTIR spectroscopy followed by MALDI mass spectroscopy to obtain a variety of information from the identical specimen.
摘要翻译：限制有目标有机分子的液滴微粒在有选择的平面溶剂基底上干燥，条件是使较大的较少溶解性分析物朝向沉积物的边缘部分分离析出。使用白光和FTIR假色的微光谱仪成像可以识别感兴趣的点，并且通常垂直于衬底定向的相同光学器件选择性地从沉积物中的选定点捕获正常的拉曼光谱。使用各种数据技术来操作光谱，以提取关于以微微摩尔浓度存在的分析物的可靠信息。所选择的点也可以进行FTIR光谱，然后进行MALDI质谱，从相同的样品获得各种信息。

3. 发明申请

US20050275837A1 Process and apparatus for segregation and testing by spectral analysis of solid deposits derived from liquid mixtures 有权
标题翻译：通过对来自液体混合物的固体沉积物的光谱分析进行分离和测试的方法和装置
公开(公告)号：US20050275837A1
公开(公告)日：2005-12-15
申请号：US10821231
申请日：2004-04-08
申请人： Dongmao Zhang , Dor Ben-Amotz , Yong Xie , Vincent Davisson , Melissa Mrozek , Corasi Ortiz
发明人： Dongmao Zhang , Dor Ben-Amotz , Yong Xie , Vincent Davisson , Melissa Mrozek , Corasi Ortiz
IPC分类号： G01N21/65 , G01J3/44
CPC分类号： G01N21/3563 , B82Y30/00 , G01N21/658 , G01N2001/4027 , G01N2021/3595
摘要： Micro-droplets of liquid confining organic molecules of interest are dried on selected planar solvo-phobic substrates under conditions facilitating segregated precipitation of the larger, less soluable analytes toward edge portions of the deposit. Micro-spectrometer imaging using white light and FTIR false color can identify points of interest, and the same optics generally directed perpendicularly to the substrates selectively captures normal Raman spectra from selected points in the deposit. The spectra are manipulated using various data techniques to extract reliable information concerning analytes present at pico-Molar levels. The selected spots can also be subjected to FTIR spectroscopy followed by MALDI mass spectroscopy to obtain a variety of information from the identical specimen.
摘要翻译：限制有目标有机分子的液滴微粒在有选择的平面溶剂基底上干燥，条件是使较大的较少溶解性分析物朝向沉积物的边缘部分分离析出。使用白光和FTIR假色的微光谱仪成像可以识别感兴趣的点，并且通常垂直于衬底定向的相同光学器件选择性地从沉积物中的选定点捕获正常的拉曼光谱。使用各种数据技术来操作光谱，以提取关于以微微摩尔浓度存在的分析物的可靠信息。所选择的点也可以进行FTIR光谱，然后进行MALDI质谱，从相同的样品获得各种信息。

4. 外观设计

USD973438S1 Pasta press attachment 有权
公开(公告)号：USD973438S1
公开(公告)日：2022-12-27
申请号：US29847789
申请日：2022-07-27
申请人： Yong Xie
设计人： Yong Xie

5. 外观设计

USD921999S1 Pet feeder 有权
公开(公告)号：USD921999S1
公开(公告)日：2021-06-08
申请号：US29768380
申请日：2021-01-29
申请人： Yong Xie
设计人： Yong Xie

6. 发明授权

US10588068B2 Fast cell reselection 有权
公开(公告)号：US10588068B2
公开(公告)日：2020-03-10
申请号：US15762439
申请日：2015-12-29
申请人： QUALCOMM INCORPORATED , Ling Xie , Shiau-He Tsai , Jie Mao , Yan Zhang , Huichun Chen , Shanshan Wang , Song Tian , Yong Xie
发明人： Ling Xie , Shiau-He Tsai , Jie Mao , Yan Zhang , Huichun Chen , Shanshan Wang , Song Tian , Yong Xie
IPC分类号： H04W36/00 , H04W36/30 , H04W48/20 , H04W48/16
摘要： A user equipment (UE) expedites cell reselection. In one instance, the UE starts a reselection timer for reselecting to a neighbor cell when a signal quality of a serving cell is determined to fall below a first threshold. The UE then expedites reselecting to the neighbor cell based on a difference between the signal quality of the serving cell and the signal quality of the neighbor cell when the signal quality of the serving cell falls below a second threshold.

7. 发明授权

US08914005B2 Method and system for network logout of a mobile station in idle mode 有权
标题翻译：空闲模式下移动台网络注销的方法和系统
公开(公告)号：US08914005B2
公开(公告)日：2014-12-16
申请号：US13441914
申请日：2012-04-09
申请人： Jianjun Wu , Yong Xie
发明人： Jianjun Wu , Yong Xie
IPC分类号： H04W52/02 , H04W60/06 , H04L29/12 , H04W64/00 , H04W76/06
CPC分类号： H04W60/06 , H04L29/12273 , H04L61/2053 , H04W64/00 , H04W76/30
摘要： A method for a network side to logout a mobile station (MS) in an idle mode is provided. The method includes receiving, by a paging agent of network side entities, a location update request message carrying a power-off indication sent from the MS; sending, by the paging agent, a location update confirm message, to an anchor paging controller/location register of the network side entities. According to the location update confirm message, the anchor paging controller/location register triggers at least one network side entity of the network side entities to release resources associated with the MS and delete a context of the MS stored in the at least one network side entity. Accordingly, the system resources are saved.
摘要翻译：提供了一种用于网络侧以空闲模式注销移动台（MS）的方法。该方法包括由网络侧实体的寻呼代理接收携带从MS发送的断电指示的位置更新请求消息; 由寻呼代理发送位置更新确认消息给网络侧实体的锚寻呼控制器/位置寄存器。根据所述位置更新确认消息，所述锚定寻呼控制器/位置寄存器触发所述网络侧实体的至少一个网络侧实体以释放与所述MS相关联的资源，并且删除存储在所述至少一个网络侧实体中的所述MS的上下文。因此，系统资源被保存。

8. 发明申请

US20130281730A1 PREPARATION OF 5-AMINOSALICYLIC ACID BY GAS PHASE CATALYTIC CARBOXYLATION 有权
标题翻译：通过气相催化羰氧化制备5-氨基苯甲酸
公开(公告)号：US20130281730A1
公开(公告)日：2013-10-24
申请号：US13997303
申请日：2011-10-20
申请人： Guangxing Li , Jinjin Li , Dajian Zhu , Qiang Jiang , Lingli Cai , Yong Xie , Lixin Gan
发明人： Guangxing Li , Jinjin Li , Dajian Zhu , Qiang Jiang , Lingli Cai , Yong Xie , Lixin Gan
IPC分类号： C07C229/64
CPC分类号： C07C229/64 , C07C227/20 , C07C231/12 , C07C233/54
摘要： Disclosed is a process for preparing 5-aminosalicylic acid by gas phase catalytic carboxylation, characterized in that carbon dioxide is introduced into a system of p-acetaminophenol and a basic compound at a temperature of 150° C.˜220° C. and a pressure of 0.5˜5.0 MPa in the presence of a catalyst, so as to carry out a gas phase catalytic carboxylation reaction to form a 5-aminosalicylate, and the crude product 5-aminosalicylate is separated, and then acidified to prepare 5-aminosalicylic acid (5-ASA). Since the gas phase catalytic reaction replaces a solid phase thermo-chemical reaction, the reaction is significantly improved in terms of the process flow, reaction conditions, product quality and energy consumption. In addition, the reaction has a short reaction time, good selectivity, high yield and no formation of wastes during the reaction, and is suitable for industrial production.
摘要翻译：公开了通过气相催化羧化制备5-氨基水杨酸的方法，其特征在于在150℃〜220℃的温度下将二氧化碳引入对乙酰氨基苯酚和碱性化合物的体系中，在催化剂存在下为0.5〜5.0MPa，进行气相催化羧化反应以形成5-氨基水杨酸盐，并将5-氨基水杨酸粗产物分离，然后酸化以制备5-氨基水杨酸（ 5-ASA）。由于气相催化反应代替了固相热化学反应，反应在工艺流程，反应条件，产品质量和能耗方面都得到了显着改善。此外，反应时间短，选择性好，产率高，反应时不产生废物，适用于工业生产。

9. 发明授权

US08212997B1 Chromatic confocal point sensor optical pen with extended measuring range 有权
标题翻译：色共焦点传感器光笔，扩展测量范围
公开(公告)号：US08212997B1
公开(公告)日：2012-07-03
申请号：US13033565
申请日：2011-02-23
申请人： Yong Xie
发明人： Yong Xie
IPC分类号： G01C3/08
CPC分类号： G01B11/026 , G01B2210/50
摘要： A chromatic confocal point sensor optical pen comprises a multi-stage optical configuration providing an enhanced range-to-resolution ratio. The optical configuration comprises at least first and last axially dispersive focusing elements that combine to contribute to the overall axial chromatic dispersion of the optical pen. The first focusing element receives source radiation and focuses that radiation at a first focal region internal to the multi-stage optical configuration and the last focusing element receives radiation from a last focal region internal to the multi-stage optical configuration and outputs the measurement beam. Intermediate focusing elements may provide additional focal regions internal to the multi-stage optical configuration. This configuration provides an unprecedented combination of extended sensing range, compact lens diameter, and high numerical aperture. The focusing elements may comprise refractive lenses or diffractive optical elements.
摘要翻译：彩色共焦点传感器光笔包括提供增强的分辨率范围的多级光学配置。光学构造包括至少第一和最后的轴向色散聚焦元件，其组合以有助于光笔的整体轴向色散。第一聚焦元件接收源辐射并将该辐射聚焦在多级光学配置内部的第一焦点区域，并且最后的聚焦元件接收来自多级光学配置内部的最后聚焦区域的辐射并输出测量光束。中间聚焦元件可以在多级光学配置内部提供附加的焦点区域。该配置提供了前所未有的扩展感测范围，紧凑的镜头直径和高数值孔径的组合。聚焦元件可以包括折射透镜或衍射光学元件。

10. 发明授权

US08129962B2 Low dropout voltage regulator with clamping 有权
标题翻译：低压差稳压器带钳位
公开(公告)号：US08129962B2
公开(公告)日：2012-03-06
申请号：US12192482
申请日：2008-08-15
申请人： Yong Xie , Gregory G. Romas, Jr.
发明人： Yong Xie , Gregory G. Romas, Jr.
IPC分类号： G05F1/00
CPC分类号： G05F1/565
摘要： Apparatus and methods for reducing output load transients of a low dropout voltage regulator (“LDO”) are disclosed herein. A voltage regulator includes an output driver coupled to a regulator output pin, the output driver provides current to a load external to the regulator. A clamping device is coupled between the output pin and an internal node of the regulator. The clamping device forces a voltage at a control input of the output driver to follow the voltage at the output pin when the output driver is disabled.
摘要翻译：本文公开了用于降低低压差稳压器（“LDO”）的输出负载瞬变的装置和方法。电压调节器包括耦合到调节器输出引脚的输出驱动器，输出驱动器向调节器外部的负载提供电流。钳位装置耦合在输出引脚和调节器的内部节点之间。当输出驱动器被禁用时，钳位装置强制输出驱动器的控制输入端的电压跟随输出引脚上的电压。

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