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1. 发明申请

US20080159959A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases 审中-公开
标题翻译：用于非侵入性成像，评估和治疗关节炎和其他炎症疾病的大分子递送系统
公开(公告)号：US20080159959A1
公开(公告)日：2008-07-03
申请号：US10591258
申请日：2005-03-30
申请人： Dong Wang , Jindrich Kopecek , Scott C. Miller , Pavla Kopeckova
发明人： Dong Wang , Jindrich Kopecek , Scott C. Miller , Pavla Kopeckova
IPC分类号： A61K47/48 , A61K47/30 , A61K38/02 , A61K31/44 , A61K38/13 , A61K33/34 , A61K49/12 , A61P29/00 , A61K49/00 , A61K33/24 , A61K31/197 , A61K31/519 , A61K47/38
CPC分类号： A61K49/0054 , A61K47/58 , A61K49/0041 , A61K49/128
摘要： This invention relates to biotechnology, more particularly, to water-soluble polymeric delivery systems for the imaging, evaluation and/or treatment of rheumatoid arthritis and other inflammatory diseases. Using modern MR imaging techniques, the specific accumulation of macromolecules in arthritic joints in adjuvant-induced arthritis in rats is demonstrated. The strong correlation between the uptake and retention of the MR contrast agent labeled polymer with histopathological features of inflammation and local tissue damage demonstrates the practical applications of the macromolecular delivery system of the invention.
摘要翻译：本发明涉及生物技术，更具体地涉及用于成像，评估和/或治疗类风湿性关节炎和其它炎性疾病的水溶性聚合物递送系统。使用现代MR成像技术，证明了大鼠在佐剂诱导的关节炎中关节炎关节中大分子的特异性积累。 MR造影剂标记的聚合物的吸收和保留与炎症和局部组织损伤的组织病理特征之间的强相关性证明了本发明的大分子递送系统的实际应用。

2. 发明授权

US10092662B2 Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases 有权
公开(公告)号：US10092662B2
公开(公告)日：2018-10-09
申请号：US10591258
申请日：2005-03-30
申请人： Dong Wang , Jindrich Kopecek , Scott C. Miller , Pavla Kopeckova
发明人： Dong Wang , Jindrich Kopecek , Scott C. Miller , Pavla Kopeckova
IPC分类号： A61K47/58 , A61K49/00 , A61K49/12
摘要： This invention relates to biotechnology, more particularly, to water-soluble polymeric delivery systems for the imaging, evaluation and/or treatment of rheumatoid arthritis and other inflammatory diseases. Using modern MR imaging techniques, the specific accumulation of macromolecules in arthritic joints in adjuvant-induced arthritis in rats is demonstrated. The strong correlation between the uptake and retention of the MR contrast agent labeled polymer with histopathological features of inflammation and local tissue damage demonstrates the practical applications of the macromolecular delivery system of the invention.

3. 发明授权

US08332914B2 Mobility access gateway 有权
标题翻译：移动接入网关
公开(公告)号：US08332914B2
公开(公告)日：2012-12-11
申请号：US12489204
申请日：2009-06-22
申请人： Milind M. Buddhikot , Girish P. Chandranmenon , Seung-Jae Han , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli
发明人： Milind M. Buddhikot , Girish P. Chandranmenon , Seung-Jae Han , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli
IPC分类号： H04W36/00 , G06F15/16
CPC分类号： H04L63/02 , H04L63/0869 , H04L67/306 , H04L69/16 , H04L69/161 , H04L69/329 , H04W12/06 , H04W80/04 , H04W88/16
摘要： A gateway for mobile access includes a foreign agent that receives user profile data and session state data from a home authentication, authorization and accounting (AAA) system of a mobile node, and a dynamic packet filter that performs multi-layer filtering based on the user profile data. The foreign agent transfers a session from a first network to a second network without session interruption, using the session state data, when the mobile node moves from the first network to the second network. The packet filter permits Internet access by the mobile node without passing Internet data requested by the mobile node through the first network.
摘要翻译：用于移动接入的网关包括从移动节点的归属认证，授权和计费（AAA）系统接收用户简档数据和会话状态数据的外地代理，以及基于用户执行多层过滤的动态分组过滤器资料数据。当移动节点从第一网络移动到第二网络时，外部代理使用会话状态数据将会话从第一网络传送到第二网络而没有会话中断。分组过滤器允许移动节点进行因特网接入，而不通过移动节点通过第一网络请求的因特网数据。

4. 发明授权

US08174982B2 Integrated web cache 有权
标题翻译：集成Web缓存
公开(公告)号：US08174982B2
公开(公告)日：2012-05-08
申请号：US12359714
申请日：2009-01-26
申请人： Milind M. Buddhikot , Girish P. Chandranmenon , Seung-Jae Han , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli
发明人： Milind M. Buddhikot , Girish P. Chandranmenon , Seung-Jae Han , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli
IPC分类号： H04J1/16
CPC分类号： H04L12/2856 , H04L61/2015 , H04L63/02 , H04L63/08 , H04L63/0869 , H04L63/10 , H04L67/2842 , H04L67/2871 , H04L67/306 , H04L69/329 , H04W36/0011 , H04W80/04 , H04W88/16
摘要： A gateway for mobile communications comprises a cache for storing network data recently downloaded from a network, a foreign agent, and a packet filter that directs requests for the network data from a mobile node to the cache. The packet filter directs the requested network data from the cache to the mobile node by way of the foreign agent, without forwarding the requested network data to a home agent of the mobile node.
摘要翻译：用于移动通信的网关包括用于存储从网络最近下载的网络数据的高速缓存，外部代理以及将网络数据的请求从移动节点引导到高速缓存的分组过滤器。分组过滤器通过外部代理将请求的网络数据从高速缓存引导到移动节点，而不将请求的网络数据转发到移动节点的归属代理。

5. 发明授权

US08081567B2 Method and apparatus for detecting wireless data subscribers using natted devices 有权
标题翻译：用于使用发送的设备检测无线数据订户的方法和装置
公开(公告)号：US08081567B2
公开(公告)日：2011-12-20
申请号：US12011908
申请日：2008-01-30
申请人： Li (Erran) Li , Tian Bu , Scott C. Miller , Aiyou Chen
发明人： Li (Erran) Li , Tian Bu , Scott C. Miller , Aiyou Chen
IPC分类号： G08C15/00
CPC分类号： H04L29/12339 , H04L61/2503 , H04W8/005
摘要： A system and method for network based detection of wireless data subscribers using network address translation devices is provided. The method includes identifying a minimum number of devices showing the same internet protocol address. Packet identification sequences may include port numbers or internet protocol identification numbers. The method continues with grouping these applications by their packet identification sequences and applying detection logic where detection logic yields a conclusion that there are multiple host computers when a set of applications appears in a plurality of packet identification sequences. This method is particularly useful when internet protocol addresses are dynamic, as opposed to static. This method overcomes previous embodiments known in the art by being able to account for and work with live traffic, which enables real time detection.
摘要翻译：提供了一种使用网络地址转换设备进行网络检测的无线数据用户的系统和方法。该方法包括识别显示相同互联网协议地址的设备的最小数量。分组识别序列可以包括端口号或因特网协议标识号。该方法继续通过其分组标识序列对这些应用进行分组，并应用检测逻辑，其中检测逻辑产生一组结论在多个分组识别序列中出现时存在多个主计算机的结论。当互联网协议地址是动态的，而不是静态时，这种方法特别有用。该方法克服了本领域已知的以前的实施例，其能够考虑和使用实时流量，从而实现实时检测。

6. 发明申请

US20100023763A1 MULTI-INTERFACE MOBILITY CLIENT 有权
标题翻译：多界面移动客户端
公开(公告)号：US20100023763A1
公开(公告)日：2010-01-28
申请号：US12568315
申请日：2009-09-28
申请人： Girish P. Chandranmenon , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli , Salim Virani
发明人： Girish P. Chandranmenon , Yui-Wah Lee , Scott C. Miller , Luca Salgarelli , Salim Virani
IPC分类号： H04L9/32 , H04W4/00
CPC分类号： H04W36/14 , H04L63/04 , H04L63/08 , H04L69/16 , H04L69/162 , H04L69/165 , H04L69/168 , H04M7/123 , H04M7/128 , H04W48/18 , H04W80/04 , H04W88/06 , H04W88/16
摘要： A mobile node comprises: a plurality of network interfaces, each with a respective device driver; a network layer; a multi-interface driver capable of communication with each network interface by way of the respective device driver for that network interface, the multi-interface driver handling communications from the network layer to any of the network interfaces; the multi-interface driver switching from a first one of the network interfaces to a second one of the network interfaces by changing the one of the plurality of network interfaces with which the multi-interface driver communicates, while hiding the switching from the network layer.
摘要翻译：移动节点包括：多个网络接口，每个具有相应的设备驱动器; 网络层; 多接口驱动器，其能够通过相应的用于该网络接口的设备驱动器与每个网络接口通信，所述多接口驱动器处理从网络层到任何网络接口的通信; 所述多接口驱动器通过改变所述多接口驱动器与之通信的多个网络接口中的一个，同时隐藏来自所述网络层的切换，从所述网络接口中的第一网络接口切换到所述网络接口中的第一网络接口。

7. 发明申请

US20090088147A1 Method and system for correlating IP layer traffic and wirless layer elements in a UMTS/GSM network 有权
标题翻译：在UMTS / GSM网络中将IP层流量与无线层元素相关联的方法和系统
公开(公告)号：US20090088147A1
公开(公告)日：2009-04-02
申请号：US11905242
申请日：2007-09-28
申请人： Tian BU , Ruth Schaefer Gayde , Scott C. Miller , Kathleen Ellen Moczulewski , Alex Ibrahim Moukalled , Samphel Norden
发明人： Tian BU , Ruth Schaefer Gayde , Scott C. Miller , Kathleen Ellen Moczulewski , Alex Ibrahim Moukalled , Samphel Norden
IPC分类号： H04Q7/20
CPC分类号： H04W12/12 , H04L63/1416 , H04L63/1458 , H04W24/08 , H04W80/04
摘要： The present invention relates to a correlation module for correlating IP layer traffic and wireless layer network elements in a network. According to an example embodiment, the correlation module includes an RNC analyzer, a Gn snoop unit, and/or a mapping unit. The RNC analyzer is configured to collect wireless layer network element information from at least one RNC. The Gn snoop unit is configured to collect wireless layer network element information and IP layer traffic information from at least one Gn interface between a serving GPRS support node and a gateway GPRS support node. The mapping unit is configured to map the IP layer traffic and the wireless layer network elements in the network based on the collected IP layer traffic information and the collected wireless layer network element information. A method of correlating IP layer traffic and wireless layer network elements in a network is also disclosed.
摘要翻译：本发明涉及一种用于使IP层业务与网络中的无线层网元相关的相关模块。根据示例实施例，相关模块包括RNC分析器，Gn窥探单元和/或映射单元。 RNC分析器被配置为从至少一个RNC收集无线层网元信息。 Gn监听单元被配置为从服务GPRS支持节点和网关GPRS支持节点之间的至少一个Gn接口收集无线层网元信息和IP层业务信息。映射单元基于收集的IP层业务信息和收集的无线层网元信息，配置IP层流量和网络中的无线层网元。还公开了一种将IP层业务与无线层网元相关联在网络中的方法。

8. 发明申请

US20080108365A1 METHOD AND APPARATUS FOR SPECTRUM ALLOCATION IN WIRELESS NETWORKS 有权
标题翻译：无线网络中频谱分配的方法与装置
公开(公告)号：US20080108365A1
公开(公告)日：2008-05-08
申请号：US11557176
申请日：2006-11-07
申请人： Milind M. Buddhikot , Scott C. Miller , Kevin Ryan
发明人： Milind M. Buddhikot , Scott C. Miller , Kevin Ryan
IPC分类号： H04Q7/20
CPC分类号： H04W16/10 , H04W16/14 , H04W24/02 , H04W72/048
摘要： The invention includes a method and apparatus for dynamically allocating spectrum available within a region including a plurality of base stations. The method includes obtaining a plurality of spectrum demands associated with at least a portion of the base stations, each spectrum demand requesting a portion of the available spectrum, and determining a plurality of spectrum allocations satisfying at least a portion of the spectrum demands. The spectrum allocations are determined by processing the spectrum demands using network information such as base station information associated with the base stations and region information such as terrain information associated with the region. The region information may include signal propagation information.
摘要翻译：本发明包括一种用于在包括多个基站的区域内动态分配可用频谱的方法和装置。该方法包括获得与至少一部分基站相关联的多个频谱需求，每个频谱需求请求可用频谱的一部分，以及确定满足频谱需求的至少一部分的多个频谱分配。通过使用诸如与基站相关联的基站信息的网络信息和诸如与该区域相关联的地形信息的区域信息来处理频谱需求来确定频谱分配。区域信息可以包括信号传播信息。

9. 发明授权

US06235757B1 Substituted heterocycles 失效
标题翻译：取代的杂环
公开(公告)号：US06235757B1
公开(公告)日：2001-05-22
申请号：US09519307
申请日：2000-03-06
申请人： Scott C. Miller , Robert T. Jacobs , Ashokkumar B. Shenvi
发明人： Scott C. Miller , Robert T. Jacobs , Ashokkumar B. Shenvi
IPC分类号： A61K31445
CPC分类号： C07D401/06 , C07D401/14
摘要： Compounds of formula I wherein Q1, Q2, Q3, Q4 and Q5 have any of the meanings given in the specification, their N-oxides, and their pharmacuetically acceptable salts are nonpeptide antagonists NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
摘要翻译：在Q1，Q2，Q3，Q4和Q5中的式I化合物具有说明书中给出的任何含义，它们的N-氧化物及其药理学上可接受的盐是可用于治疗哮喘的非肽拮抗剂NKA等。还公开了药物组合物，制备式I化合物的方法和中间体。

10. 发明授权

US6120560A Process and apparatus for pattern dyeing of textile substrates 有权
标题翻译：纺织品基材图案染色的工艺和装置
公开(公告)号：US6120560A
公开(公告)日：2000-09-19
申请号：US264457
申请日：1999-03-08
申请人： Scott C. Miller , Frank W. Teaster , Matthew R. Walker
发明人： Scott C. Miller , Frank W. Teaster , Matthew R. Walker
IPC分类号： D06B11/00 , D06P5/00
CPC分类号： D06B11/0059 , Y10S8/917 , Y10S8/929 , Y10S8/932
摘要： A method and apparatus for pattern dyeing of textile substrates in which the dyeing is done in two stages. In the first stage, a dye is uniformly applied in a manner that allows the dye to fix on contact. The uniformly dyed substrate is then moved under a series of spaced arrays, each array being associated with a separate color and being comprised of a plurality of individually controlled liquid dye applicators. Liquid dye of a given color is selectively applied through one or more dye applicators as the substrate passes under the array associated with that color. The applied dye remains unfixed until the substrate passes under all the arrays and the patterning is complete, whereupon all dye applied by the dye applicators is fixed by steaming or other appropriate application of energy to the substrate.
摘要翻译：纺织基材图案染色的方法和装置，其中染色分两步进行。在第一阶段中，染料以允许染料固定接触的方式均匀地施加。然后均匀染色的基底在一系列间隔的阵列下移动，每个阵列与单独的颜色相关联，并且由多个单独控制的液体染料施用器组成。当衬底通过与该颜色相关联的阵列下时，给定颜色的液体染料通过一种或多种染料涂布器选择性地施加。所施加的染料保持未固定，直到基底在所有阵列下通过并且图案化完成，由染料施加器施加的所有染料通过蒸汽或其它适当的能量施加到基底而固定。

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