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    • 3. 发明授权
    • Certain 4-oxo-3-benzoylvalerothiolactones
    • 某些4-氧代-3-苯甲酰基戊内硫醇内酯
    • US4780124A
    • 1988-10-25
    • US135892
    • 1987-12-21
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • A01N43/16A01N43/18C07D309/32C07D335/02A01N43/02
    • C07D335/02A01N43/16A01N43/18C07D309/32
    • Compounds having the formula ##STR1## wherein X is sulfur;R is halogen; C.sub.1 -C.sub.2 alkyl; C.sub.1 -C.sub.2 alkoxy; nitro; cyano; C.sub.1 -C.sub.2 haloalkyl; or R.sup.a SO.sub.n -- wherein n is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl;R.sup.1 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.3 and R.sup.4 together form a single bond; orR.sup.1 and R.sup.3 together are alkylene having 2-5 carbon atoms; orR.sup.2 and R.sup.4 together are alkylene having 2-5 carbon atoms; andR.sup.5 and R.sup.6 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 -C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -- wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10)--NR.sup.c R.sup.d wherein R.sup.c and R.sup.d independently are hydrogen or C.sub.1 -C.sub.4 alkyl; (11) R.sup.e C(O)-- wherein R.sup.e is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy; or (12) --SO.sub.2 NR.sup.c R.sup.d wherein R.sup.c and R.sup.d are as defined; and (13) --N(R.sup.c)C(O)R.sup.d wherein R.sup.c and R.sup.d are as defined and their salts are useful as herbicides.
    • 具有式“IMAGE”的化合物,其中X是硫; R是卤素; C1-C2烷基; C1-C2烷氧基; 硝基 氰基; C1-C2卤代烷基; 或RaSOn-,其中n为0或2,Ra为C1-C2烷基; R1是氢或C1-C4烷基; R2是氢或C1-C4烷基; R3是氢或C1-C4烷基; R4是氢或C1-C4烷基; 或R3和R4一起形成单键; 或者R 1和R 3一起是具有2-5个碳原子的亚烷基; 或者R 2和R 4一起是具有2-5个碳原子的亚烷基; 和R 5和R 6独立地为(1)氢; (2)卤素; (3)C 1 -C 4烷基; (4)C1-C4烷氧基; (5)三氟甲氧基; (6)氰基; (7)硝基; (8)C 1 -C 4卤代烷基; (9)RbSO n-,其中n是整数0,1或2; 并且R b是(a)C 1 -C 4烷基; (b)被卤素或氰基取代的C 1 -C 4烷基; (c)苯基; 或(d)苄基; (10)-NRcRd其中Rc和Rd独立地是氢或C1-C4烷基; (11)Re C(O) - 其中Re是C 1 -C 4烷基或C 1 -C 4烷氧基; 或(12)-SO 2 NR c R d其中R c和R d如所定义; 和(13)-N(Rc)C(O)R d,其中R c和R d如所定义,并且它们的盐可用作除草剂。
    • 4. 发明授权
    • Certain 4-oxo-3-benzoylvalerolactones and thiolactones
    • 某些4-氧代-3-苯甲酰基戊内酯和硫内酯
    • US4808733A
    • 1989-02-28
    • US135216
    • 1987-12-21
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • A01N43/16A01N43/18C07D309/32C07D335/02C07D309/30
    • A01N43/18A01N43/16C07D309/32C07D335/02
    • An intermediate compound having the structural formula ##STR1## wherein X is oxygen or sulfur;R is halogen; C.sub.1 -C.sub.2 alkyl; C.sub.1 -C.sub.2 alkoxy; nitro; cyano; C.sub.1 -C.sub.2 haloalkyl; or R.sup.a SO.sub.n --wherein n is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl;R.sup.1 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.1 and R.sup.3 together are alkylene having 2-5 cation atoms; orR.sup.2 and R.sup.4 together are alkylene having 2-5 carbon atoms; andR.sup.5 and R.sup.6 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 -C.sub.4 alkoxy; (5) trifuoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n --wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10) --NR.sup.C R.sup.d wherein R.sup.c and R.sup.d independently are hydrogen or C.sub.1 -C.sub.4 alkyl; (11) R.sup.e C(O)--wherein R.sup.e is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy; or (12) --SO.sub.2 NR.sup.c R.sup.d are as defined; and (13) N(R.sup.c)C((O)R.sup.d wherein R.sup.c and R.sup.d are as defined.The title of the invention is not descriptive. A new title is required that is clearly indicative of the invention to which the claims are directed.The following title is provided: Intermediates for preparing 4-oxo-3-benzoylvalerolactones and thiolactones.
    • 具有结构式为“IMAGE”的中间体化合物,其中X为氧或硫; R是卤素; C1-C2烷基; C1-C2烷氧基; 硝基 氰基; C1-C2卤代烷基; 或RaSO n - ,其中n为0或2,Ra为C 1 -C 2烷基; R1是氢或C1-C4烷基; R2是氢或C1-C4烷基; R3是氢或C1-C4烷基; R4是氢或C1-C4烷基; R1和R3一起是具有2-5个阳离子原子的亚烷基; 或者R 2和R 4一起是具有2-5个碳原子的亚烷基; 和R 5和R 6独立地为(1)氢; (2)卤素; (3)C 1 -C 4烷基; (4)C1-C4烷氧基; (5)三氟甲氧基; (6)氰基; (7)硝基; (8)C 1 -C 4卤代烷基; (9)RbSOn-其中n是整数0,1或2; 并且R b是(a)C 1 -C 4烷基; (b)被卤素或氰基取代的C 1 -C 4烷基; (c)苯基; 或(d)苄基; (10)-NRCRd其中Rc和Rd独立地是氢或C1-C4烷基; (11)ReC(O) - 其中Re为C 1 -C 4烷基或C 1 -C 4烷氧基; 或(12)-SO 2 NR c R d如所定义; 和(13)N(R c)C((O)Rd,其中R c和R d如所定义)。本发明的标题不是描述性的。需要新的标题,其清楚地指示了权利要求所针对的发明。 提供以下标题:制备4-氧代-3-苯甲酰基戊内酯和硫内酯的中间体。
    • 5. 发明授权
    • Certain 4-oxo-3-benzoylvalerolactones and thiolactones
    • 某些4-氧代-3-苯甲酰基戊内酯和硫内酯
    • US4780123A
    • 1988-10-25
    • US135208
    • 1987-12-21
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • Christopher G. KnudsenWilliam J. MichaelyDonald R. JamesHsiao-Ling M. Chin
    • A01N43/16A01N43/18C07D309/32C07D335/02A01N43/00
    • C07D309/32A01N43/16A01N43/18C07D335/02
    • Compounds having the formula ##STR1## wherein X is oxygen or sulfur;R is halogen; C.sub.1 -C.sub.2 alkyl; C.sub.1 -C.sub.2 alkoxy; nitro; cyano; C.sub.1 -C.sub.2 haloalkyl; or R.sup.a SO.sub.n -- wherein n is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl;R.sup.1 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.3 and R.sup.4 together form a single bond; orR.sup.1 and R.sup.3 together are alkylene having 2-5 carbon atoms; orR.sup.2 and R.sup.4 together are alkylene having 2-5 carbon atoms; andR.sup.5 and R.sup.6 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 -C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -- wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10) --NR.sup.c R.sup.d wherein R.sup.c and R.sup.d independently are hydrogen or C.sub.1 -C.sub.4 alkyl; (11) R.sup.e C(O)-- wherein R.sup.e is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy; or (12) --SO.sub.2 NR.sup.c R.sup.d wherein R.sup.c and R.sup.d are as defined; and (13) --N(R.sup.c)C(O)R.sup.d wherein R.sup.c and R.sup.d are as defined and their salts are useful as herbicides.
    • 具有式“IMAGE”的化合物,其中X是氧或硫; R是卤素; C1-C2烷基; C1-C2烷氧基; 硝基 氰基; C1-C2卤代烷基; 或RaSOn-,其中n为0或2,Ra为C1-C2烷基; R1是氢或C1-C4烷基; R2是氢或C1-C4烷基; R3是氢或C1-C4烷基; R4是氢或C1-C4烷基; 或R3和R4一起形成单键; 或者R 1和R 3一起是具有2-5个碳原子的亚烷基; 或者R 2和R 4一起是具有2-5个碳原子的亚烷基; 和R 5和R 6独立地为(1)氢; (2)卤素; (3)C 1 -C 4烷基; (4)C1-C4烷氧基; (5)三氟甲氧基; (6)氰基; (7)硝基; (8)C 1 -C 4卤代烷基; (9)RbSO n-,其中n是整数0,1或2; 并且R b是(a)C 1 -C 4烷基; (b)被卤素或氰基取代的C 1 -C 4烷基; (c)苯基; 或(d)苄基; (10)-NRcRd其中Rc和Rd独立地是氢或C1-C4烷基; (11)ReC(O) - 其中Re为C1-C4烷基或C1-C4烷氧基; 或(12)-SO 2 NR c R d其中R c和R d如所定义; 和(13)-N(R c)C(O)R d,其中R c和R d如所定义,并且它们的盐可用作除草剂。
    • 9. 发明授权
    • Certain substituted 3-(substituted oxy)-2-benzoyl-cyclohex-2-enones
    • 某些取代的3-(取代的氧基)-2-苯甲酰基 - 环己-2-烯酮
    • US4918236A
    • 1990-04-17
    • US871989
    • 1986-06-09
    • Christopher G. KnudsenWilliam J. Michaely
    • Christopher G. KnudsenWilliam J. Michaely
    • A01N35/06A01N37/02A01N37/10A01N37/34A01N37/42A01N37/44A01N37/46A01N37/48A01N41/04A01N47/02C07C45/00C07C45/68C07C49/225C07C49/753C07C49/84C07C67/00C07C69/03C07C69/76C07C201/00C07C205/45C07C231/00C07C233/33C07C233/43C07C253/00C07C255/56C07C301/00C07C309/63C07C311/15C07C311/16C07C313/00C07C317/14C07C317/24C07C317/36C07C317/40C07C317/44C07C317/46C07C317/48C07C317/50C07C323/22C07C323/62C07C323/65C07C323/67
    • C07C205/45A01N35/06A01N37/02A01N37/10A01N41/04C07C309/00C07C45/68C07C49/84
    • A compound of the formula ##STR1## wherein R is halogen, C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, nitro; cyano; C.sub.1 -C.sub.2 haloalkyl, or R.sup.a SO.sub.m -wherein m is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl; R.sup.1 is hydrogen or C.sub.1 -C.sub.2 alkyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; or R.sup.1 and R.sup.2 together are alkylene having 2 to 5 carbon atoms; R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl; or R.sup.3 and R.sup.4 together are oxo; R.sup.5 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.6 is hydrogen or C.sub.1 -C.sub.4 alkyl; or R.sup.5 and R.sup.6 together are alkylene having 2 to 5 carbon atoms; R.sup.7 and R.sup.8 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 - C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10) -NR.sup.c R.sup.d wherein R.sup.c and R.sup.d independently are hydrogen or C.sub.1 -C.sub.4 alkyl; (11) R.sup.e C(O)- wherein R.sup.e is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy; (12) SO.sub.2 NR.sup.c R.sup.d wherein R.sup.c and R.sup.d are as defined; or (13) -N(R.sup.c)C(O)R.sup.d wherein R.sup.c and R.sup.d are as defined; and R.sup.9 is (a) C.sub.1 -C.sub.6 alkyl; (b) C.sub.4 -C.sub.6 cycloalkyl; (c) substituted C.sub.1 -C.sub.6 alkyl; (d) phenyl-SO.sub.2 -; (e) substituted phenyl-SO.sub.2 -; (f) C.sub.1 -C.sub.6 -alkyl-SO.sub.2 -, optionally substituted; (g) C.sub.1 -C.sub.6 alkyl-C(O)-, optionally substituted; (h) phenyl-C(O)-, optionally substituted; (i) benzyl; or (h) C.sub.3 -C.sub.6 alkenyl.
    • 其中R是卤素,C 1 -C 2烷基,C 1 -C 2烷氧基,硝基; 氰基; C1-C2卤代烷基或RaSOm-,其中m为0或2,Ra为C1-C2烷基; R1是氢或C1-C2烷基; R2是氢或C1-C4烷基; 或R 1和R 2一起是具有2至5个碳原子的亚烷基; R3是氢或C1-C4烷基; R4是氢或C1-C4烷基; 或R3和R4一起是氧代; R5是氢或C1-C4烷基; R6是氢或C1-C4烷基; 或R 5和R 6一起是具有2至5个碳原子的亚烷基; R7和R8独立地是(1)氢; (2)卤素; (3)C 1 -C 4烷基; (4)C 1 -C 4烷氧基; (5)三氟甲氧基; (6)氰基; (7)硝基; (8)C 1 -C 4卤代烷基; (9)RbSOn-其中n是整数0,1或2; 并且R b是(a)C 1 -C 4烷基; (b)被卤素或氰基取代的C 1 -C 4烷基; (c)苯基; 或(d)苄基; (10)-NRcRd其中Rc和Rd独立地是氢或C1-C4烷基; (11)ReC(O) - 其中Re为C1-C4烷基或C1-C4烷氧基; (12)SO2NRcRd其中Rc和Rd如所定义; 或(13)-N(R c)C(O)R d,其中R c和R d如所定义; 并且R 9为(a)C 1 -C 6烷基; (b)C 4 -C 6环烷基; (c)取代的C 1 -C 6烷基; (d)苯基-SO 2 - ; (e)取代的苯基-SO 2 - ; (f)任选取代的C 1 -C 6烷基-SO 2 - ; (g)任选取代的C 1 -C 6烷基-C(O) - (h)苯基-C(O) - ,任选取代的; (i)苄基; 或(h)C 3 -C 6烯基。
    • 10. 发明授权
    • Certain substituted 3-(substituted oxy)-2-benzoyl-cyclohex-2-enones
    • 某些取代的3-(取代的氧基)-2-苯甲酰基 - 环己-2-烯酮
    • US4957540A
    • 1990-09-18
    • US453432
    • 1989-12-19
    • Christopher G. KnudsenWilliam J. Michaely
    • Christopher G. KnudsenWilliam J. Michaely
    • A01N35/06A01N37/02A01N37/10A01N41/04C07C45/68C07C49/84
    • C07C205/45A01N35/06A01N37/02A01N37/10A01N41/04C07C309/00C07C45/68C07C49/84
    • A compound of the formula ##STR1## wherein R is halogen, C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, nitro; cyano; C.sub.1 14 C.sub.2 haloalkyl, or R.sup.a SO.sub.m -- wherein m is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl; R.sup.1 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; or R.sup.1 and R.sup.2 together are alkylene having 2 to 5 carbon atoms; R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.4 is hydrogen or C.sub.1 14 C.sub.4 alkyl; or R.sup.3 and R.sup.4 together are oxo; R.sup.5 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.6 is hydrogen or C.sub.1 -C.sub.4 alkyl; or R.sup.5 and R.sup.6 together are alkylene having 2 to 5 carbon atoms; R.sup.7 and R.sup.8 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub. 1 -C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -- wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10) --NR.sup.c R.sup.d wherein R.sup.c and R.sup.d independently are hydrogen or C.sub.1 -C.sub.4 alkyl; (11) R.sup.e C(O)-- wherein R.sup.e is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy; (12) SO.sub.2 NR.sup.c R.sup.d wherein R.sup.c and R.sup.d are as defined; or (13) --N(R.sup.c)C(O)R.sup.d wherein R.sup.c and R.sup.d are as defined; and R.sup.9 is (a) C.sub.1 14 C.sub.6 alkyl; (b) C.sub.4 -C.sub.6 cycloalkyl; (c) substituted C.sub.1 -C.sub.6 alkyl; (d) phenyl--SO.sub.2 --; (e) substituted phenyl--SO.sub.2 --; (f) C.sub.1 -C.sub.6 --alkyl--SO.sub.2 --, optionally substituted; (g) C.sub.1 -C.sub.6 alkyl--C(O)--, optionally substituted; (h) phenyl--C(O)--, optionally substituted; (i) benzyl; or (h) C.sub.3 -C.sub.6 alkenyl.
    • 其中R是卤素,C 1 -C 2烷基,C 1 -C 2烷氧基,硝基; 氰基; C114 C2卤代烷基或RaSOm-,其中m为0或2,Ra为C1-C2烷基; R1是氢或C1-C4烷基; R2是氢或C1-C4烷基; 或R 1和R 2一起是具有2至5个碳原子的亚烷基; R3是氢或C1-C4烷基; R4是氢或C114 C4烷基; 或R3和R4一起是氧代; R5是氢或C1-C4烷基; R6是氢或C1-C4烷基; 或R 5和R 6一起是具有2至5个碳原子的亚烷基; R7和R8独立地是(1)氢; (2)卤素; (3)C 1 -C 4烷基; (4)C 1 -C 4烷氧基; (5)三氟甲氧基; (6)氰基; (7)硝基; (8)C 1 -C 4卤代烷基; (9)RbSO n-,其中n是整数0,1或2; 并且R b是(a)C 1 -C 4烷基; (b)被卤素或氰基取代的C 1 -C 4烷基; (c)苯基; 或(d)苄基; (10)-NRcRd其中Rc和Rd独立地是氢或C1-C4烷基; (11)ReC(O) - 其中Re为C1-C4烷基或C1-C4烷氧基; (12)SO2NRcRd其中Rc和Rd如所定义; 或(13)-N(R c)C(O)R d,其中R c和R d如所定义; 和R9是(a)C114 C6烷基; (b)C 4 -C 6环烷基; (c)取代的C 1 -C 6烷基; (d)苯基-SO 2 - ; (e)取代的苯基-SO 2 - ; (f)任选取代的C 1 -C 6烷基-SO 2 - ; (g)任选取代的C 1 -C 6烷基-C(O) - (h)苯基-C(O) - ,任选取代的; (i)苄基; 或(h)C 3 -C 6烯基。