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    • 2. 发明授权
    • Method of manufacturing gelatin
    • 制造明胶的方法
    • US5908921A
    • 1999-06-01
    • US185443
    • 1998-11-03
    • Scott W. LaRocheDavid J. RoyJohn S. Brand
    • Scott W. LaRocheDavid J. RoyJohn S. Brand
    • A23L29/20C08L99/00C09H3/00G03C1/047A61K38/17C08H1/00
    • C09H3/00
    • The present invention is a process for the manufacture of gelatin which includes providing a collagen containing material and demineralizing the collagen containing material to produce ossein. The ossein is added to a water solution containing at least 3% sodium hydroxide or potassium hydroxide and at least 3% sodium sulfate for a time sufficient to form a reacted slurry. The reacted slurry is heated to a temperature of at least 45.degree. C. for a time sufficient to solubilize the ossein thereby producing a solution containing gelatin. The pH of the solution containing gelatin is raised to greater than 9.8. The pH of the solution containing gelatin is reduced with a sulfate salt of a divalent or trivalent metal to a neutral pH (between 7.0 and 8.0). The pH of the gelatin solution is then lowered to between 5.0 and 6.0 and a polymeric flocculant is added to the gelatin solution in an amount of less than 0.1% based on the dry weight of the gelatin to form a floc and the floc is removed. The resulting gelatin is filtered and desalted.
    • 本发明是一种制造明胶的方法,其包括提供含胶原的材料并使含胶原蛋白质软化以产生骨胶原。 将骨胶蛋白加入含有至少3%氢氧化钠或氢氧化钾和至少3%硫酸钠的水溶液中足以形成反应浆液的时间。 将反应的浆液加热到至少45℃的温度足以溶解骨胶原的时间,从而产生含有明胶的溶液。 含有明胶溶液的pH升高至9.8以上。 用二价或三价金属的硫酸盐还原含有明胶的溶液的pH至中性pH(7.0至8.0)。 然后将明胶溶液的pH降低至5.0至6.0,并且基于明胶的干重将小于0.1%的量将聚合物絮凝剂加入到明胶溶液中,以形成絮凝物并除去絮凝物。 将所得明胶过滤并脱盐。