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    • 2. 发明申请
    • ENHANCED EFFICACY SELF-STERILIZING ORTHOPEDIC IMPLANTS
    • 增强自杀自杀性手术植入物
    • WO2014152649A1
    • 2014-09-25
    • PCT/US2014/027576
    • 2014-03-14
    • DIFUSION TECHNOLOGIES, INC.
    • CRUDDEN, Joseph J.
    • A61L2/00A61L2/04
    • A61L27/18A61L2/238A61L27/54A61L2300/102A61L2300/404A61L2300/602A61L2300/62C08L71/00
    • Methods for imparting antimicrobial properties to polymers using ceramics, preferably zeolites, as a cation cage, to deliver and dose one or more antimicrobial cations. Polymer containing antimicrobial metal ions is contacted with a strong acid or a suitable solvent, such as by immersion, dipping, spraying, etc. After contacting with the acid for a sufficient amount of time, the article can be washed and further processed in a conventional manner. Suitable polymers include thermoplastic resins, especially polyaryletherketones such as polyetheretherketone (PEEK) and polyetherketoneketone (PEKK). Suitable acids include sulfuric acid, nitric acid, mixtures thereof, glacial acetic acid, citric acid solution, and phosphoric acid, particularly in combination with nitric and sulfuric acid.
    • 使用陶瓷优选沸石作为阳离子笼的聚合物赋予抗微生物性能以递送和剂量一种或多种抗微生物阳离子的方法。 含有抗微生物金属离子的聚合物与强酸或合适的溶剂接触,例如通过浸渍,浸渍,喷涂等。在与酸接触足够的时间后,可以用常规方法洗涤并进一步加工制品 方式。 合适的聚合物包括热塑性树脂,特别是聚芳醚酮如聚醚醚酮(PEEK)和聚醚酮酮(PEKK)。 合适的酸包括硫酸,硝酸,其混合物,冰醋酸,柠檬酸溶液和磷酸,特别是与硝酸和硫酸组合。