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1. 发明申请

US20060211004A1 Methods and compositions for determining non-specific cytotoxicity of a transfection agent 审中-公开
公开(公告)号：US20060211004A1
公开(公告)日：2006-09-21
申请号：US11150409
申请日：2005-06-10
申请人： Diane Ilsley , Arindam Bhattacharjee , Emily Anderson , Anastasia Khvorova
发明人： Diane Ilsley , Arindam Bhattacharjee , Emily Anderson , Anastasia Khvorova
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： C12Q1/6883 , C12Q2600/142 , C12Q2600/158
摘要： Methods and compositions for determining cytotoxicity of a transfection agent are provided. In one aspect, a cell is contacted with a transfection agent. Following contact, a cytotoxic marker profile of the cell is evaluated to determine whether the transfection agent has mediated a cytotoxic response in the cell. Also provided are compositions and reagents, and kits for practicing the subject methods. The subject methods and compositions find use in a variety of different applications.

2. 发明申请

US20060183701A1 Methods and compositions for determining non-specific cytotoxicity of a transfection agent 审中-公开
标题翻译：用于测定转染试剂的非特异性细胞毒性的方法和组合物
公开(公告)号：US20060183701A1
公开(公告)日：2006-08-17
申请号：US11059209
申请日：2005-02-15
申请人： Diane Ilsley , Arindam Bhattacharjee
发明人： Diane Ilsley , Arindam Bhattacharjee
IPC分类号： A61K48/00 , C12Q1/68 , C12N15/63
CPC分类号： C12Q1/6809
摘要： Methods and compositions for determining cytotoxicity of a transfection agent are provided. In one aspect, a cell is contacted with a transfection agent. Following contact, a cytotoxic marker profile of the cell is evaluated to determine whether the transfection agent has mediated a cytotoxic response in the cell. Also provided are compositions and reagents, and kits for practicing the subject methods. The subject methods and compositions find use in a variety of different applications.
摘要翻译：提供了用于确定转染剂的细胞毒性的方法和组合物。在一个方面，使细胞与转染剂接触。接触后，评估细胞的细胞毒性标记物谱，以确定转染试剂是否在细胞中介导细胞毒性反应。还提供了组合物和试剂以及用于实施本发明方法的试剂盒。主题方法和组合物可用于各种不同的应用。

3. 发明申请

US20060078889A1 Array-based methods for producing ribonucleic acids 审中-公开
标题翻译：用于产生核糖核酸的基于阵列的方法
公开(公告)号：US20060078889A1
公开(公告)日：2006-04-13
申请号：US10961991
申请日：2004-10-08
申请人： Arindam Bhattacharjee , Stephanie Fulmer-Smentek , Diane Ilsley , Eric Leproust
发明人： Arindam Bhattacharjee , Stephanie Fulmer-Smentek , Diane Ilsley , Eric Leproust
IPC分类号： C12Q1/68 , G06F19/00 , C12P19/34
CPC分类号： C12Q1/6837 , C12Q1/6865 , C12Q2565/525 , C12Q2565/537 , C12Q2531/143
摘要： Methods and compositions for generating pluralities of ribonucleic acids are provided. In the subject methods, an array is employed as a template in an in vitro transcription reaction. Also provided are the arrays employed in the subject methods and kits for practicing the subject methods. The ribonucleic acid pluralities produced by the subject methods find use in a variety of different applications, including differential gene expression analysis and gene-silencing applications.
摘要翻译：提供了产生多种核糖核酸的方法和组合物。在本方法中，在体外转录反应中使用阵列作为模板。还提供了用于实践本发明方法的主题方法和试剂盒中使用的阵列。通过本发明方法产生的核糖核酸多样性可用于各种不同的应用，包括差异基因表达分析和基因沉默应用。

4. 发明授权

US09552403B2 Converting data models into in-database analysis models 有权
标题翻译：将数据模型转换为数据库内分析模型
公开(公告)号：US09552403B2
公开(公告)日：2017-01-24
申请号：US13762546
申请日：2013-02-08
申请人： Arindam Bhattacharjee , Srinivasa Raghu Garimella , Ajay Kumar Gupta , Unmesh Sreedharan , Girish Kalasa Ganesh Pai
发明人： Arindam Bhattacharjee , Srinivasa Raghu Garimella , Ajay Kumar Gupta , Unmesh Sreedharan , Girish Kalasa Ganesh Pai
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/30569
摘要： Data sets are analyzed to discover trends and determine predictive data models. A data model is determined based on analyzing the data set with a specific algorithm from a set of different analytical algorithms. The data model is stored in a structural file format. The data model is converted into an instantiated object model with the use of a predefined object model. The instantiated object model is converted into an in-database analysis model to score new data within a database system. The scoring is based on the logic in the data model. The in-database analysis model is stored on a database server part of a database system to provide analytical functionality defined in the data model. The new data can be scored with the in-database analysis model. The new data is not extracted from the database system and the scoring is accomplished in-memory.
摘要翻译：分析数据集以发现趋势并确定预测数据模型。基于通过一组不同分析算法利用特定算法分析数据集来确定数据模型。数据模型以结构文件格式存储。使用预定义的对象模型将数据模型转换为实例化对象模型。实例化的对象模型被转换成数据库内分析模型，以对数据库系统中的新数据进行评分。得分是基于数据模型中的逻辑。数据库内分析模型存储在数据库系统的数据库服务器部分，以提供数据模型中定义的分析功能。可以使用数据库内分析模型对新数据进行评分。新数据不是从数据库系统中提取出来的，而是在内存中完成评分。

5. 发明申请

US20140067457A1 WORKFLOW EXECUTION FRAMEWORK 审中-公开
标题翻译：工作流程执行框架
公开(公告)号：US20140067457A1
公开(公告)日：2014-03-06
申请号：US13596355
申请日：2012-08-28
申请人： ABHISHEK NAGENDRA , Arindam Bhattacharjee , Girish Kalasa Ganesh Pai
发明人： ABHISHEK NAGENDRA , Arindam Bhattacharjee , Girish Kalasa Ganesh Pai
IPC分类号： G06Q10/06
CPC分类号： G06Q10/0633 , G06Q10/06
摘要： A workflow execution framework is generated to execute a received workflow. The workflow is semantically analyzed to determine workflow chain and associated workflow components. To execute the workflow chain, a terminal component in the workflow chain and a corresponding sequential hierarchy of the workflow components are detected. A result descriptor of a data source component corresponding to the terminal component is computed and stored in an execution state table. Result descriptors are computed for the workflow components succeeding the data source component in the sequential hierarchy and are stored in the execution state table. Upon detecting a dataflow between the data source component and one of the succeeding workflow components, data along each row of the execution state table is extracted to process the one of the succeeding workflow components. The workflow is executed by processing the workflow components associated with the workflow chain, thereby executing the workflow chain.
摘要翻译：生成工作流执行框架来执行接收到的工作流。语义分析工作流以确定工作流链和相关的工作流组件。为了执行工作流链，检测工作流链中的终端组件和工作流组件的对应顺序层次。计算与终端组件对应的数据源组件的结果描述符，并将其存储在执行状态表中。针对顺序层次结构中数据源组件的后续工作流组件计算结果描述符，并存储在执行状态表中。在检测到数据源组件和后续工作流组件之一之间的数据流时，提取执行状态表的每行的数据以处理后续工作流组件中的一个。通过处理与工作流链相关联的工作流组件来执行工作流，从而执行工作流链。

6. 发明申请

US20130166573A1 Managing Business Objects Data Sources 有权
标题翻译：管理业务对象数据源
公开(公告)号：US20130166573A1
公开(公告)日：2013-06-27
申请号：US13337990
申请日：2011-12-27
申请人： Ganesh Vaitheeswaran , Manasa Ranjan Tripathy , Raghavendra Nagaraja , Arindam Bhattacharjee , Rahul Kumar Jha , Nithin Moolky Kamath
发明人： Ganesh Vaitheeswaran , Manasa Ranjan Tripathy , Raghavendra Nagaraja , Arindam Bhattacharjee , Rahul Kumar Jha , Nithin Moolky Kamath
IPC分类号： G06F17/30
CPC分类号： G06F17/30389
摘要： Methods, computer-readable media, and systems for managing business objects data sources. A search query that includes multiple query terms is received. Each query term at least partially represents metadata associated with one of multiple business objects data sources that each stores multiple data items. Multiple search index documents are searched to identify one or more business objects data sources that are each associated with metadata at least partially represented by each query term. Multiple metadata tables are searched to identify metadata associated with each identified business objects data source. The identified business objects data sources are searched for data items that satisfy the identified metadata. Representations of the data items and the metadata are provided in response to receiving the search query.
摘要翻译：方法，计算机可读介质和用于管理业务对象数据源的系统。收到包含多个查询条件的搜索查询。每个查询项至少部分地表示与每个存储多个数据项的多个业务对象数据源中的一个相关联的元数据。搜索多个搜索索引文档以识别每个与每个查询项至少部分表示的元数据相关联的一个或多个业务对象数据源。搜索多个元数据表以识别与每个已标识的业务对象数据源相关联的元数据。搜索所识别的业务对象数据源以获得满足所识别的元数据的数据项。响应于接收到搜索查询而提供数据项和元数据的表示。

7. 发明授权

US09092478B2 Managing business objects data sources 有权
标题翻译：管理业务对象数据源
公开(公告)号：US09092478B2
公开(公告)日：2015-07-28
申请号：US13337990
申请日：2011-12-27
申请人： Ganesh Vaitheeswaran , Manasa Ranjan Tripathy , Raghavendra Nagaraja , Arindam Bhattacharjee , Rahul Kumar Jha , Nithin Moolky Kamath
发明人： Ganesh Vaitheeswaran , Manasa Ranjan Tripathy , Raghavendra Nagaraja , Arindam Bhattacharjee , Rahul Kumar Jha , Nithin Moolky Kamath
IPC分类号： G06F17/30
CPC分类号： G06F17/30389
摘要： Methods, computer-readable media, and systems for managing business objects data sources. A search query that includes multiple query terms is received. Each query term at least partially represents metadata associated with one of multiple business objects data sources that each stores multiple data items. Multiple search index documents are searched to identify one or more business objects data sources that are each associated with metadata at least partially represented by each query term. Multiple metadata tables are searched to identify metadata associated with each identified business objects data source. The identified business objects data sources are searched for data items that satisfy the identified metadata. Representations of the data items and the metadata are provided in response to receiving the search query.
摘要翻译：方法，计算机可读介质和用于管理业务对象数据源的系统。收到包含多个查询条件的搜索查询。每个查询项至少部分地表示与每个存储多个数据项的多个业务对象数据源中的一个相关联的元数据。搜索多个搜索索引文档以识别每个与每个查询项至少部分表示的元数据相关联的一个或多个业务对象数据源。搜索多个元数据表以识别与每个已标识的业务对象数据源相关联的元数据。搜索所识别的业务对象数据源以获得满足所识别的元数据的数据项。响应于接收到搜索查询而提供数据项和元数据的表示。

8. 发明授权

US08938475B2 Managing business objects data sources 有权
标题翻译：管理业务对象数据源
公开(公告)号：US08938475B2
公开(公告)日：2015-01-20
申请号：US13338027
申请日：2011-12-27
申请人： Ganesh Vaitheeswaran , Arindam Bhattacharjee , Raghavendra Nagaraja , Manasa Ranjan Tripathy , Nithin Moolky Kamath , Rahul Kumar Jha
发明人： Ganesh Vaitheeswaran , Arindam Bhattacharjee , Raghavendra Nagaraja , Manasa Ranjan Tripathy , Nithin Moolky Kamath , Rahul Kumar Jha
IPC分类号： G06F17/30
CPC分类号： G06F17/30566
摘要： Methods, non-transitory computer-readable media, and systems for managing business objects data sources. Multiple business objects data sources, each storing multiple data items, are accessed. For each data source, multiple computer-searchable index documents and multiple metadata tables, including master tables and mapping tables, are generated. The multiple computer-searchable index documents and the multiple metadata tables are provided to perform a search for data items in the multiple business objects data sources.
摘要翻译：方法，非暂时性计算机可读介质和用于管理业务对象数据源的系统。访问多个业务对象数据源，每个存储多个数据项。对于每个数据源，生成多个计算机可搜索的索引文档和多个元数据表，包括主表和映射表。提供多个计算机可搜索索引文档和多个元数据表以执行对多个业务对象数据源中的数据项的搜索。

9. 发明申请

US20140304263A1 IN-DATABASE PROVISIONING OF DATA 审中-公开
标题翻译：数据库的数据库提供
公开(公告)号：US20140304263A1
公开(公告)日：2014-10-09
申请号：US13856441
申请日：2013-04-04
申请人： Ganesh Vaitheeswaran , Rahul Kumar Jha , Suraj Pai Airody , Anup Kumar Rai , Arindam Bhattacharjee
发明人： Ganesh Vaitheeswaran , Rahul Kumar Jha , Suraj Pai Airody , Anup Kumar Rai , Arindam Bhattacharjee
IPC分类号： G06F17/30
CPC分类号： G06F17/30598
摘要： A user uploads date sets through a client to a database. The data sets are provisioned in the database for in-database searching. The data sets are evaluated and classifications for the columns of the tables that include the data set are detected. Columns content may be classified into different analysis types, aggregation types, formats, categories, hierarchies, etc. Metadata is generated based on the evaluation of the data sets. A schema is used to store the metadata that describes the detected classification of the columns. The schema is stored in the database and is used when a search in the database is performed.
摘要翻译：用户通过客户端将数据集上传到数据库。数据集在数据库中配置用于数据库内搜索。评估数据集，并检测包含数据集的表的列的分类。列内容可以分为不同的分析类型，聚合类型，格式，类别，层次等。元数据是基于数据集的评估而生成的。模式用于存储描述检测到的列分类的元数据。模式存储在数据库中，并在执行数据库中的搜索时使用。

10. 发明申请

US20110153589A1 DOCUMENT INDEXING BASED ON CATEGORIZATION AND PRIORITIZATION 有权
标题翻译：基于分类和优先排序的文献索引
公开(公告)号：US20110153589A1
公开(公告)日：2011-06-23
申请号：US12642893
申请日：2009-12-21
申请人： GANESH VAITHEESWARAN , Arindam Bhattacharjee , Ravichandran Mahadevan , Suresh Pasumarthi
发明人： GANESH VAITHEESWARAN , Arindam Bhattacharjee , Ravichandran Mahadevan , Suresh Pasumarthi
IPC分类号： G06F17/30 , G06F9/46
CPC分类号： G06F17/30705 , G06F9/5083
摘要： Disclosed are methods and systems for improving indexing throughput. The methods and systems involve receiving one or more documents for indexing, categorizing the one or more documents based on a document type, a document size and a processing priority, assigning buckets to the categorized one or more documents according to the document type, the document size and the processing priority and scheduling the buckets for processing based on a document type priority, a bucket type and number of threads available to process the buckets.
摘要翻译：公开了用于提高分选产量的方法和系统。方法和系统包括接收一个或多个文件进行索引，根据文档类型，文档大小和处理优先级对一个或多个文档进行分类，根据文档类型将文档类型分配给分类的一个或多个文档，文档大小和处理优先级，并且基于文档类型优先级，桶类型和可用于处理桶的线程数来调度用于处理的桶。

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