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1. 发明申请

US20060252956A1 Process for reactive esterification distillation 有权
标题翻译：反应酯化蒸馏方法
公开(公告)号：US20060252956A1
公开(公告)日：2006-11-09
申请号：US11414672
申请日：2006-04-28
申请人： Dennis Miller , Navinchandra Asthana , Aspi Kolah , Dung Vu , Carl Lira
发明人： Dennis Miller , Navinchandra Asthana , Aspi Kolah , Dung Vu , Carl Lira
IPC分类号： C07C69/76 , C07C69/52 , C07C69/34
CPC分类号： C07C67/08 , B01D3/009 , C07C67/03 , Y02P20/127 , C07C69/40 , C07C69/704 , C07C69/68
摘要： A process for producing organic acid di- or tri-esters, particularly citric acid tri-esters, with the available acid groups esterified using countercurrent reactive distillation using acid catalysts in a structured packing is described. In the reactive distillation an organic acid di- or tri-ester is formed by chemical reaction and purified to its final state within the single column. Organic acid di- or tri-esters are produced at relatively low cost, with less waste production in by-products of the reaction, and in a less complicated manner than prior processes. Organic acid di- and tri-esters have uses as solvents, as plasticizers and in conversion products.
摘要翻译：描述了使用酸性催化剂在规整填料中使用逆流反应蒸馏酯化的可用酸基团来生产有机酸二酯或三酯，特别是柠檬酸三酯的方法。在反应蒸馏中，有机酸二酯或三酯通过化学反应形成，并在单塔内纯化至其最终状态。有机酸二酯或三酯以相对较低的成本生产，反应的副产物的废物产生较少，并且以比现有方法更不复杂的方式生产。有机酸二酯和三酯可用作溶剂，增塑剂和转化产物。

2. 发明申请

US20060014977A1 Process for production of organic acid esters 有权
标题翻译：生产有机酸酯的方法
公开(公告)号：US20060014977A1
公开(公告)日：2006-01-19
申请号：US10894307
申请日：2004-07-19
申请人： Dennis Miller , Navinchandra Asthana , Aspi Kolah , Carl Lira
发明人： Dennis Miller , Navinchandra Asthana , Aspi Kolah , Carl Lira
IPC分类号： C07C67/08
CPC分类号： B01D3/009 , C07C67/03 , C07C67/08 , Y02P20/127 , C07C69/68
摘要： A process for producing organic acid esters using continuous countercurrent reactive distillation using acid catalysts in a structured packing in a single column (10) is described. In the reactive distillation an organic acid ester is formed by chemical reaction and can be purified to its final state within the single column. Organic acid esters are produced at relatively low cost, with less waste production, and in a less complicated manner than prior processes. Organic acid ester have uses as solvents, as intermediate chemicals, and in consumer products.
摘要翻译：描述了使用在单柱（10）中的规整填料中使用酸催化剂的连续逆流反应蒸馏来生产有机酸酯的方法。在反应蒸馏中，有机酸酯通过化学反应形成，并可在单塔内纯化至其最终状态。有机酸酯以相对较低的成本生产，具有更少的废物产生，并且以比现有方法更不复杂的方式生产。有机酸酯可以用作溶剂，作为中间体化学品，也可用于消费品。

3. 发明申请

US20060199970A1 Process for production of a composition useful as a fuel 有权
标题翻译：生产可用作燃料的组合物的方法
公开(公告)号：US20060199970A1
公开(公告)日：2006-09-07
申请号：US11364241
申请日：2006-02-28
申请人： Dennis Miller , Lars Peereboom , Aspi Kolah , Navinchandra Asthana , Carl Lira
发明人： Dennis Miller , Lars Peereboom , Aspi Kolah , Navinchandra Asthana , Carl Lira
IPC分类号： C07C51/43
CPC分类号： C10L1/026 , C07C67/03 , C07D317/20 , C11C3/00 , C11C3/003 , Y02E50/13 , Y02P20/127 , Y02P20/582 , C07C69/52 , C07C69/24
摘要： A process for the preparation of a fuel oil (diesel fuel or heating oil) composition which is a mixture of an alkanol tranesterified fatty acid ester triglyceride and an acetal of glycerol is described. The process preferably provides a prestep of the formation of at least some of the alkanol transesterified triglyceride containing the glycerol for use in the formation of the acetal of glycerol. The composition can also be formed from a reaction of 1,1- dimethoxy- or 1,1-diethoxyethane and glycerol to form the acetal in the alkanol transesterified triglyceride.
摘要翻译：描述了制备作为烷醇酯化脂肪酸酯甘油三酯和甘油缩醛的混合物的燃料油（柴油燃料或加热油）组合物的方法。该方法优选提供至少一些含有甘油的链烷醇酯交换的甘油三酯的形成的预成型，用于形成甘油的缩醛。该组合物也可以由1,1-二甲氧基 - 或1,1-二乙氧基乙烷与甘油的反应形成，以在烷醇酯交换的甘油三酸酯中形成缩醛。

4. 发明申请

US20120014889A1 METHODS FOR MAKING 1,3-DIHYDROXYACETONE (DHA) FROM GLYCEROL 有权
标题翻译：从甘油制备1,3-二羟基乙酮（DHA）的方法
公开(公告)号：US20120014889A1
公开(公告)日：2012-01-19
申请号：US13183114
申请日：2011-07-14
申请人： Dennis Miller , Xi Hong , Carl Lira , Omar McGiveron
发明人： Dennis Miller , Xi Hong , Carl Lira , Omar McGiveron
IPC分类号： C07C45/42 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61K8/35 , A61K31/401
CPC分类号： C07C45/60 , C07D317/20 , C07D319/06 , Y02P20/127 , C07C49/17
摘要： A method comprising reacting glycerol with acetaldehyde or 1,1-diethoxyethane to produce 1,3-dihydroxyacetone (DHA), without using fermentation or direct oxidation of the glycerol is provided. DHA is useful in various products, including as a sunless tanning agent.
摘要翻译：提供了一种方法，其包括使甘油与乙醛或1,1-二乙氧基乙烷反应以产生1,3-二羟基丙酮（DHA），而不使用甘油的发酵或直接氧化。 DHA可用于各种产品，包括作为日晒鞣剂。

5. 发明授权

US08293935B2 Carboxylic acid recovery and methods related thereto 有权
标题翻译：羧酸回收及其相关方法
公开(公告)号：US08293935B2
公开(公告)日：2012-10-23
申请号：US13145731
申请日：2010-12-02
申请人： Alvaro Orjuela , Abraham Yanez-McKay , Carl Lira , Dennis Miller
发明人： Alvaro Orjuela , Abraham Yanez-McKay , Carl Lira , Dennis Miller
IPC分类号： C07C69/66 , C07C69/40 , C07C69/34
CPC分类号： C07C51/02 , C07C67/08 , Y02P20/127 , C07C55/10 , C07C69/40
摘要： A method of producing an alkyl ester of a carboxylic acid is provided, the method comprising: adding an alkanol and a mineral acid to a carboxylic acid salt to provide a carboxylic acid/alkanol solution and a precipitated mineral acid salt; separating the mineral acid salt from the carboxylic acid/alkanol solution; esterifying the carboxylic acid; and isolating an alkyl ester of the carboxylic acid.
摘要翻译：提供了一种制备羧酸烷基酯的方法，所述方法包括：向羧酸盐中加入链烷醇和无机酸以提供羧酸/烷醇溶液和沉淀的无机酸盐; 从羧酸/烷醇溶液中分离无机酸盐; 酯化羧酸; 并分离出羧酸的烷基酯。

6. 发明申请

US20110275851A1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO 有权
标题翻译：羧酸回收方法及其相关方法
公开(公告)号：US20110275851A1
公开(公告)日：2011-11-10
申请号：US13145731
申请日：2010-12-02
申请人： Alvaro Orjuela , Abraham Yanez-Mckav , Carl Lira , Dennis Miller
发明人： Alvaro Orjuela , Abraham Yanez-Mckav , Carl Lira , Dennis Miller
IPC分类号： C07C67/08
CPC分类号： C07C51/02 , C07C67/08 , Y02P20/127 , C07C55/10 , C07C69/40
摘要： A method of producing an alkyl ester of a carboxylic acid is provided, the method comprising: adding an alkanol and a mineral acid to a carboxylic acid salt to provide a carboxylic acid/alkanol solution and a precipitated mineral acid salt; separating the mineral acid salt from the carboxylic acid/alkanol solution; esterifying the carboxylic acid; and isolating an alkyl ester of the carboxylic acid.
摘要翻译：提供了一种制备羧酸烷基酯的方法，所述方法包括：向羧酸盐中加入链烷醇和无机酸以提供羧酸/烷醇溶液和沉淀的无机酸盐; 从羧酸/烷醇溶液中分离无机酸盐; 酯化羧酸; 并分离出羧酸的烷基酯。

7. 发明授权

US08735633B2 Methods for making 1,3-dihydroxyacetone (DHA) from glycerol 有权
标题翻译：从甘油制备1,3-二羟丙酮（DHA）的方法
公开(公告)号：US08735633B2
公开(公告)日：2014-05-27
申请号：US13183114
申请日：2011-07-14
申请人： Dennis Miller , Xi Hong , Carl Lira , Omar McGiveron
发明人： Dennis Miller , Xi Hong , Carl Lira , Omar McGiveron
IPC分类号： A61K31/401 , A61K8/35 , A61Q15/00 , A61Q17/04 , A61Q19/00 , C07C45/42
CPC分类号： C07C45/60 , C07D317/20 , C07D319/06 , Y02P20/127 , C07C49/17
摘要： A method comprising reacting glycerol with acetaldehyde or 1,1-diethoxyethane to produce 1,3-dihydroxyacetone (DHA), without using fermentation or direct oxidation of the glycerol is provided. DHA is useful in various products, including as a sunless tanning agent.
摘要翻译：提供了一种方法，其包括使甘油与乙醛或1,1-二乙氧基乙烷反应以产生1,3-二羟基丙酮（DHA），而不使用甘油的发酵或直接氧化。 DHA可用于各种产品，包括作为日晒鞣剂。

8. 发明授权

US09283063B2 Medical device and methods of delivering the medical device 有权
标题翻译：医疗器械及其输送方法
公开(公告)号：US09283063B2
公开(公告)日：2016-03-15
申请号：US13608919
申请日：2012-09-10
申请人： Ty Fairneny , Dennis Miller , Michael F. Weiser
发明人： Ty Fairneny , Dennis Miller , Michael F. Weiser
IPC分类号： A61F6/08 , A61F2/00
CPC分类号： A61F2/0045 , A61F2/0063 , A61F2230/006 , A61F2250/006 , A61F2250/0097
摘要： A medical device and methods of delivery of the medical device within a patient's body are disclosed by the present invention. The medical device includes a first elongate member, a second elongate member and a coupling member. The coupling member is configured to be coupled to and extend between the first elongate member and the second elongate member to couple the first elongate member to the second elongate member when the medical device is in a first configuration. The coupling member is configured to be decoupled from at least one of the first elongate member and the second elongate member when the medical device is in a second configuration.
摘要翻译：本发明公开了医疗装置和医疗装置在患者体内的输送方法。医疗装置包括第一细长构件，第二细长构件和联接构件。联接构件被构造成联接到第一细长构件和第二细长构件之间并在第一细长构件和第二细长构件之间延伸，以在医疗装置处于第一构造时将第一细长构件联接到第二细长构件。联接构件被构造成当医疗装置处于第二构造时与第一细长构件和第二细长构件中的至少一个分离。

9. 发明申请

US20130061855A1 MEDICAL DEVICE AND METHODS OF DELIVERING THE MEDICAL DEVICE 有权
标题翻译：医疗装置及其输送方法
公开(公告)号：US20130061855A1
公开(公告)日：2013-03-14
申请号：US13608919
申请日：2012-09-10
申请人： Ty Fairneny , Dennis Miller , Michael F. Weiser
发明人： Ty Fairneny , Dennis Miller , Michael F. Weiser
IPC分类号： A61F6/08
CPC分类号： A61F2/0045 , A61F2/0063 , A61F2230/006 , A61F2250/006 , A61F2250/0097
摘要： A medical device and methods of delivery of the medical device within a patient's body are disclosed by the present invention. The medical device includes a first elongate member, a second elongate member and a coupling member. The coupling member is configured to be coupled to and extend between the first elongate member and the second elongate member to couple the first elongate member to the second elongate member when the medical device is in a first configuration. The coupling member is configured to be decoupled from at least one of the first elongate member and the second elongate member when the medical device is in a second configuration.
摘要翻译：本发明公开了医疗装置和医疗装置在患者体内的输送方法。医疗装置包括第一细长构件，第二细长构件和联接构件。联接构件被构造成联接到第一细长构件和第二细长构件之间并在第一细长构件和第二细长构件之间延伸，以在医疗装置处于第一构造时将第一细长构件联接到第二细长构件。联接构件被构造成当医疗装置处于第二构造时与第一细长构件和第二细长构件中的至少一个分离。

10. 发明申请

US20110105836A1 System and Method for Treating Prolapse and Incontinence 有权
标题翻译：治疗萎缩和失禁的系统和方法
公开(公告)号：US20110105836A1
公开(公告)日：2011-05-05
申请号：US12939832
申请日：2010-11-04
申请人： Dennis Miller
发明人： Dennis Miller
IPC分类号： A61F2/04
CPC分类号： A61F2/0045 , A61F2/0063 , A61F2230/006
摘要： A system and method of treating vaginal prolapse and incontinence comprises a kit. The kit includes a mesh graft configured for attachment to the anterior and posterior vaginal walls to thereby treat the vaginal prolapse. A graft delivery device is also provided for introducing and placing the mesh graft to a location deep within the peritoneal cavity and for attaching the graft thereto. A leg assembly is provided and coupled to an end of the mesh graft and cooperates with the graft delivery device to anchor and affix the mesh graft to the desired anatomical structures. The method according to the present invention contemplates a laparoscopic graft placement utilizing the components of the kit.
摘要翻译：治疗阴道脱垂和失禁的系统和方法包括试剂盒。该套件包括网状移植物，其被配置为附接到前阴道壁和后阴道壁，从而治疗阴道脱垂。还提供移植物输送装置，用于将网状移植物引入和放置在腹膜腔内深处的位置，并将移植物附着到其上。提供腿部组件并且联接到网状移植物的端部并且与移植物递送装置协作以将网状移植物锚固并固定到期望的解剖结构上。根据本发明的方法考虑使用试剂盒的组分的腹腔镜移植物放置。

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