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1. 发明申请

US20060106281A1 Multi-functional endoscopic system for use in electrosurgical applications 有权
公开(公告)号：US20060106281A1
公开(公告)日：2006-05-18
申请号：US11238649
申请日：2005-09-29
申请人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor
发明人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor
IPC分类号： A61B1/00
CPC分类号： A61B1/05 , A61B1/00059 , A61B1/00087 , A61B1/00103 , A61B1/00105 , A61B1/0051 , A61B1/0052 , A61B1/018 , A61B1/12 , A61B18/1492 , A61B90/98 , G06F19/00
摘要： A multi-functional endoscopic system, for use in electrosurgical applications, that includes an imaging endoscope that may be used in combination with various electrosurgical devices, all of which are sufficiently inexpensive to manufacture, such that the endoscope and electrosurgical devices are considered single use, disposable items. The multi-functional endoscopic system of the present invention is suitable for use with a variety of common electrosurgical devices that require electrical/electronic support in order to function. The electrical/electronic support for these electrosurgical devices (e.g., an electrosurgical generator and associated controls) is integrated with the operator console of the imaging endoscope of the multi-functional endoscopic system of the present invention, rather than provided as a separate device. In another embodiment of the invention, an imaging endoscope is provided that integrates or combines the functions of both an imaging endoscope and an electrosurgical device, which can be controlled by a single handheld controller.

2. 发明申请

US20060173244A1 System and method of obstruction removal 有权
标题翻译：障碍物清除系统和方法
公开(公告)号：US20060173244A1
公开(公告)日：2006-08-03
申请号：US11241829
申请日：2005-09-30
申请人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor , Lucien Couvillon , Luis Maseda , Donald Hovey , Mark Adams , William Shaw , Laurence Brenner
发明人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor , Lucien Couvillon , Luis Maseda , Donald Hovey , Mark Adams , William Shaw , Laurence Brenner
IPC分类号： A61B1/12 , A61B1/00
CPC分类号： A61B1/12 , A61B1/00085 , A61B1/00087 , A61B1/00091 , A61B1/00094 , A61B1/015 , A61B1/018 , A61B1/05 , A61B1/0607 , A61B1/0676 , A61B1/0684 , A61B1/125 , A61B1/126 , A61B1/31 , A61B2017/22092 , A61B2017/320775 , A61M3/0279 , A61M3/0283
摘要： In one aspect, the present invention is a system for preparing a patient for an endoscopy procedure, such as a colonoscopy. The endoscopic preparation and examination system includes an endoscope, a source of irrigation and aspiration, and a control unit. The endoscope includes an elongated flexible shaft with a distal tip and a proximal end, at least one aspiration lumen and at least one irrigation lumen. A plurality of irrigation ports are functionally connected to the at least one irrigation lumen and a plurality of aspiration ports are functionally connected to the at least one aspiration lumen. In another aspect, the invention provides a method of clearing an obstructed view in a patient prior to, or during an endoscopic examination.
摘要翻译：一方面，本发明是用于制备用于内窥镜检查程序的患者的系统，例如结肠镜检查。内窥镜准备和检查系统包括内窥镜，灌注源和抽吸源，以及控制单元。内窥镜包括具有远侧末端和近端的细长柔性轴，至少一个抽吸腔和至少一个冲洗腔。多个冲洗口在功能上连接到所述至少一个冲洗腔，并且多个抽吸端口在功能上连接到所述至少一个抽吸腔。在另一方面，本发明提供一种在内窥镜检查之前或期间清除患者中的阻塞视图的方法。

3. 发明申请

US20060106285A1 Fluid delivery system for use with an endoscope 有权
标题翻译：用于内窥镜的流体输送系统
公开(公告)号：US20060106285A1
公开(公告)日：2006-05-18
申请号：US11239644
申请日：2005-09-29
申请人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor , Eric Litscher
发明人： Dennis Boulais , Michael Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John O'Connor , Eric Litscher
IPC分类号： A61B1/12
CPC分类号： A61B1/015 , A61B1/00068 , A61B1/00119 , A61B1/00128 , A61B1/12 , A61B1/128 , A61M39/225
摘要： A fluid delivery system for use with an endoscope. Certain embodiments of the invention include a single, large fluid source and pump installed upon an operator console, in combination with a small fluid reservoir and pump installed within a proximal connector of the imaging endoscope, multiple fluid sources that feed a common fluid channel that are pressurized by a common pump, multiple fluid sources that feed dedicated fluid channels that are pressurized by dedicated pumps, and a small fluid reservoir and pump installed within a handheld manual controller of the imaging endoscope. The fluid delivery endoscopic systems of the present invention provide the user with the flexibility of changing fluids either in advance of a procedure or on-the-fly as needed, instead of relying on fixed fluid sources only.
摘要翻译：一种用于内窥镜的流体输送系统。本发明的某些实施例包括安装在操作员控制台上的单个大型流体源和泵与安装在成像内窥镜的近侧连接器内的小型流体储存器和泵组合，供给公共流体通道的多个流体源通过公共泵加压，多个流体源，其供应由专用泵加压的专用流体通道，以及安装在成像内窥镜的手持式手动控制器内的小型流体储存器和泵。本发明的流体输送内窥镜系统为使用者提供了根据需要在程序之前或即时更换流体的灵活性，而不是仅依赖于固定的流体源。

4. 发明授权

US08357148B2 Multi-functional endoscopic system for use in electrosurgical applications 有权
标题翻译：用于电外科应用的多功能内窥镜系统
公开(公告)号：US08357148B2
公开(公告)日：2013-01-22
申请号：US11238649
申请日：2005-09-29
申请人： Dennis R. Boulais , Michael S. Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John P. O'Connor
发明人： Dennis R. Boulais , Michael S. Banik , Vincent Turturro , Christopher Rowland , David Hoffman , John P. O'Connor
IPC分类号： A61B18/04
CPC分类号： A61B1/05 , A61B1/00059 , A61B1/00087 , A61B1/00103 , A61B1/00105 , A61B1/0051 , A61B1/0052 , A61B1/018 , A61B1/12 , A61B18/1492 , A61B90/98 , G06F19/00
摘要： A multi-functional endoscopic system, for use in electrosurgical applications, that includes an imaging endoscope that may be used in combination with various electrosurgical devices, all of which are sufficiently inexpensive to manufacture, such that the endoscope and electrosurgical devices are considered single use, disposable items. The multi-functional endoscopic system of the present invention is suitable for use with a variety of common electrosurgical devices that require electrical/electronic support in order to function. The electrical/electronic support for these electrosurgical devices (e.g., an electrosurgical generator and associated controls) is integrated with the operator console of the imaging endoscope of the multi-functional endoscopic system of the present invention, rather than provided as a separate device. In another embodiment of the invention, an imaging endoscope is provided that integrates or combines the functions of both an imaging endoscope and an electrosurgical device, which can be controlled by a single handheld controller.
摘要翻译：一种用于电外科应用的多功能内窥镜系统，其包括可与各种电外科装置组合使用的成像内窥镜，所述成像内窥镜都足够廉价制造，使得内窥镜和电外科设备被认为是单次使用的，一次性物品本发明的多功能内窥镜系统适用于需要电气/电子支撑以便起作用的各种常见的电外科装置。这些电外科装置（例如，电外科发生器和相关联的控制器）的电气/电子支撑件与本发明的多功能内窥镜系统的成像内窥镜的操作者控制台集成，而不是作为单独的装置提供。在本发明的另一个实施例中，提供一种成像内窥镜，其集成或组合了可由单个手持式控制器控制的成像内窥镜和电外科装置的功能。

5. 发明申请

US20060259041A1 Endoscopic apparatus with integrated variceal ligation device 有权
公开(公告)号：US20060259041A1
公开(公告)日：2006-11-16
申请号：US11129225
申请日：2005-05-13
申请人： David Hoffman , Christopher Rowland
发明人： David Hoffman , Christopher Rowland
IPC分类号： A61B17/10
CPC分类号： A61B1/012 , A61B1/00087 , A61B1/00103 , A61B1/018 , A61B17/12013 , A61B2017/12018 , A61B2090/0803
摘要： A variceal banding endoscope includes an elongated shaft having a distal end and a proximal end that is removably connected to a control unit. The endoscope includes a variceal banding apparatus fixedly attached to the distal end of the endoscope and capable of receiving a plurality of ligation bands. A trigger cable extends from the proximal end to the distal end of the shaft and is digitally actuated by an actuator in the control unit or handle of the scope in response to a user input device.

6. 发明申请

US20060258955A1 Endoscopic apparatus with integrated multiple biopsy device 有权
标题翻译：内窥镜装置，集成多个活检装置
公开(公告)号：US20060258955A1
公开(公告)日：2006-11-16
申请号：US11129561
申请日：2005-05-13
申请人： David Hoffman , Christopher Rowland
发明人： David Hoffman , Christopher Rowland
IPC分类号： A61B10/00 , A61B1/00
CPC分类号： A61B10/06 , A61B1/018 , A61B10/0096 , A61B2010/0225 , A61B2017/00362
摘要： An imaging endoscope comprising a shaft having a proximal end adapted to be secured to a handle, and a distal end having a biopsy forceps disposed therein. The biopsy forceps includes one or more end-effector elements that are actuated with a control cable that may be connected to the handle. The endoscope shaft includes a biopsy sample lumen that is configured to receive a biopsy sample obtained from the forceps assembly. A sample collection apparatus is attached to the handle to capture multiple biopsy samples. In some embodiments, the endoscope is a single-use endoscope.
摘要翻译：一种成像内窥镜，包括具有适于固定到手柄的近端的轴，以及设置在其中的活检钳的远端。活检钳包括一个或多个末端执行器元件，其通过可连接到手柄的控制电缆致动。内窥镜轴包括活组织检查样本腔，其构造成接收从镊子组件获得的活检样本。将样品收集装置连接到手柄以捕获多个活检样品。在一些实施例中，内窥镜是一次性内窥镜。

7. 发明授权

US09531156B2 Endoscopic light source 有权
标题翻译：内窥镜光源
公开(公告)号：US09531156B2
公开(公告)日：2016-12-27
申请号：US12487591
申请日：2009-06-18
申请人： David Hoffman , Alexandr Ikriannikov
发明人： David Hoffman , Alexandr Ikriannikov
IPC分类号： H01S5/042 , H01S5/062 , A61B1/06 , A61B1/07 , H01S5/068 , H01S5/00 , H01S5/40
CPC分类号： H01S5/06213 , A61B1/063 , A61B1/0661 , A61B1/07 , H01S5/0014 , H01S5/0427 , H01S5/0428 , H01S5/06216 , H01S5/06808 , H01S5/4025 , H01S5/4087
摘要： A light source assembly includes multiple light emitters having output that are focused and mixed onto a optical fiber leading to an endoscope or other device. The emitters can be LEDs or solid state lasers that emit different colors. A driver circuit controls the relative output intensities of the light emitters so as to produce a desired light spectrum. A driver circuit includes a buck topology connected to a controller that provides current mode control. Pulse width modulation of the buck current is provided by a semiconductor switch across a solid state laser. A second order filter, formed by the an external inductor and the output capacitance of the buck topology, minimizes AC current ripple to the laser.
摘要翻译：光源组件包括具有聚焦和混合到通向内窥镜或其它装置的光纤上的输出的多个发光体。发射器可以是发射不同颜色的LED或固态激光器。驱动器电路控制发光体的相对输出强度，以产生所需的光谱。驱动器电路包括连接到提供电流模式控制的控制器的降压拓扑。降压电流的脉冲宽度调制由跨越固态激光器的半导体开关提供。由外部电感器形成的二阶滤波器和降压拓扑的输出电容可最大限度地减少激光器的交流电流纹波。

8. 发明申请

US20140304860A1 Molecular Markers Associated with Soybean Tolerance to Low Iron Growth Conditions 审中-公开
公开(公告)号：US20140304860A1
公开(公告)日：2014-10-09
申请号：US14240895
申请日：2012-08-29
申请人： Vergel C. Concibido , Susannah G. Cooper , David Hoffman , Hongwu Jia , Thomas Jury , Bradley LaVallee , Roger L. Lussenden , Xianghai Ye
发明人： Vergel C. Concibido , Susannah G. Cooper , David Hoffman , Hongwu Jia , Thomas Jury , Bradley LaVallee , Roger L. Lussenden , Xianghai Ye
IPC分类号： C12Q1/68 , A01H5/10
CPC分类号： C12Q1/6895 , A01H1/04 , A01H5/10 , A01H6/542 , C07K14/415 , C12Q2600/156
摘要： The present invention provides methods and compositions for identifying soybean plants that are tolerant or have improved tolerance, or those that are susceptible to, iron deficient growth conditions. The methods use molecular markers to identify, select, and/or introgress genetic loci modulating phenotypic expression of an iron deficiency tolerance trait in soybean plant breeding. Methods are provided for screening germplasm entries for the performance and expression of this trait.

9. 发明申请

US20140220202A1 FOOD-GRADE FLOUR FROM DRY FRACTIONATED CORN GERM AND COLLET COMPOSITION AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：食品级干粉碎机及其组合物及其生产方法
公开(公告)号：US20140220202A1
公开(公告)日：2014-08-07
申请号：US14246288
申请日：2014-04-07
申请人： David Hoffman
发明人： David Hoffman , Kimberly Jean Sitzmann , Joseph John Furgal , Scott Paul Hoffman
IPC分类号： A23L1/10 , A23L1/00 , A23D9/02 , A23L1/015
CPC分类号： A23D9/02 , A21D2/265 , A21D6/00 , A23L5/23 , A23L7/152 , A23L7/197 , A23P30/20 , C11B1/10 , C11B3/12
摘要： A nutrient rich food-grade defatted corn germ flour derived from a dry-milled corn germ fraction is provided. The flour produced contains high levels of protein, dietary fiber, and amino acids and is low in fat. Furthermore, a method for preparing the flour by forming collets and removing oil from the dry-milled corn germ fraction is provided. The method includes: providing a dry-milled corn germ fraction; conditioning the fraction; flaking the fraction to increase surface area; adding water and steam to the flaked fraction; forming the flaked fraction into collets; removing oil from the collets by solvent-extraction; drying the collets; and processing the collets in a food-grade flourmill to obtain food-grade defatted corn germ flour with a desired consistency. The solvent-extraction process produces a miscella, a mixture of corn oil, hydrocarbon solvent, and water. The miscella may be processed through a distillation system to recover crude food-grade corn oil.
摘要翻译：提供了一种来源于干磨玉米胚芽部分的营养丰富的食品级脱脂玉米胚芽粉。生产的面粉含有高水平的蛋白质，膳食纤维和氨基酸，脂肪含量低。此外，提供了通过从干磨的玉米胚芽馏分中形成夹头和除去油来制备面粉的方法。该方法包括：提供干磨的玉米胚芽部分; 调节分数; 剥离部分以增加表面积; 将水和蒸汽加入到片状部分中; 将片状部分形成夹头; 通过溶剂萃取从油枪中除去油; 干燥夹头; 并在食品级面粉机中加工夹头，以获得具有所需一致性的食品级脱脂玉米胚芽粉。溶剂萃取过程产生米曲霉，玉米油，烃溶剂和水的混合物。可以通过蒸馏系统处理杂种以回收粗粮食级玉米油。

10. 发明授权

US08115366B2 System and method of driving ultrasonic transducers 有权
标题翻译：驱动超声波换能器的系统和方法
公开(公告)号：US08115366B2
公开(公告)日：2012-02-14
申请号：US12605311
申请日：2009-10-23
申请人： David Hoffman , David Brubaker , Alexandr Ikriannikov
发明人： David Hoffman , David Brubaker , Alexandr Ikriannikov
IPC分类号： H01L41/08
CPC分类号： B06B1/0253 , B06B2201/76
摘要： A transducer is optimally driven at or near its resonant frequency by a driver system that adapts to variations and/or changes to the resonant frequency of the transducer due to variations in piezo materials, manufacturing, assembly, component tolerances, and/or operational conditions. The system may include an output controller, a phase track controller, a frequency generator, a drive, circuitry to determine a phase angle between the transducer voltage and transducer current, and circuitry to obtain transducer admittance from the transducer voltage and transducer current.
摘要翻译：由于压电材料，制造，组件，部件公差和/或操作条件的变化，传感器被适配于变换器的谐振频率的变化和/或变化的驱动器系统在其谐振频率处或其附近被最佳地驱动。该系统可以包括输出控制器，相位轨道控制器，频率发生器，驱动器，确定换能器电压和换能器电流之间的相位角的电路，以及从换能器电压和换能器电流获得换能器导纳的电路。

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