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1. 发明授权

US09264134B2 Automatic laser shutdown and recovery in response to a link break 有权
标题翻译：自动激光关机和恢复响应链路断开
公开(公告)号：US09264134B2
公开(公告)日：2016-02-16
申请号：US12239857
申请日：2008-09-29
申请人： David Kerr , Mark LaLiberte , Avery Van Gieson , John Lai , Kim Jepsen , Wei Lu , Yan Han , Marc Placidet , Ulrik Gliese , David Copeland , Guangning Yang
发明人： David Kerr , Mark LaLiberte , Avery Van Gieson , John Lai , Kim Jepsen , Wei Lu , Yan Han , Marc Placidet , Ulrik Gliese , David Copeland , Guangning Yang
IPC分类号： H04B17/00 , H04B10/077 , H04B10/071
CPC分类号： H04B10/0773 , H04B10/071
摘要： A communication system may include a first control circuit to detect a break on a first optical link; a first optical source to supply a first optical signal on a second optical link in response to detecting the break on the first optical link, the first optical signal propagating in a first direction on the second optical link; a second control circuit to detect a presence of the first optical signal on the second optical link, and output a control signal in response to detecting the presence of the first optical signal; and a second optical source to supply a second optical signal on the second optical link, the second optical signal propagating in a second direction opposite the first direction, where the Raman pump is disabled in response to the control signal.
摘要翻译：通信系统可以包括用于检测第一光链路上的断点的第一控制电路; 第一光源，用于响应于检测到第一光链路上的断裂而在第二光链路上提供第一光信号，第一光信号在第二光链路上沿第一方向传播; 第二控制电路，用于检测所述第二光链路上的所述第一光信号的存在，并且响应于检测到所述第一光信号的存在而输出控制信号; 以及第二光源，用于在所述第二光链路上提供第二光信号，所述第二光信号在与所述第一方向相反的第二方向上传播，其中所述拉曼泵响应于所述控制信号被禁用。

2. 发明申请

US20100080553A1 AUTOMATIC LASER SHUTDOWN AND RECOVERY IN RESPONSE TO A LINK BREAK 有权
标题翻译：自动激光切断和恢复响应链接断开
公开(公告)号：US20100080553A1
公开(公告)日：2010-04-01
申请号：US12239857
申请日：2008-09-29
申请人： David Kerr , Mark Laliberte , Avery Van Gieson , John Lai , Kim Jepsen , Wei Lu , Yan Han , Marc Placidet , Ulrik Gliese , David Copeland , Guangning Yang
发明人： David Kerr , Mark Laliberte , Avery Van Gieson , John Lai , Kim Jepsen , Wei Lu , Yan Han , Marc Placidet , Ulrik Gliese , David Copeland , Guangning Yang
IPC分类号： H04B10/00
CPC分类号： H04B10/0773 , H04B10/071
摘要： A communication system may include a first control circuit to detect a break on a first optical link; a first optical source to supply a first optical signal on a second optical link in response to detecting the break on the first optical link, the first optical signal propagating in a first direction on the second optical link; a second control circuit to detect a presence of the first optical signal on the second optical link, and output a control signal in response to detecting the presence of the first optical signal; and a second optical source to supply a second optical signal on the second optical link, the second optical signal propagating in a second direction opposite the first direction, where the Raman pump is disabled in response to the control signal.
摘要翻译：通信系统可以包括用于检测第一光链路上的断点的第一控制电路; 第一光源，用于响应于检测到第一光链路上的断裂而在第二光链路上提供第一光信号，第一光信号在第二光链路上沿第一方向传播; 第二控制电路，用于检测所述第二光链路上的所述第一光信号的存在，并且响应于检测到所述第一光信号的存在而输出控制信号; 以及第二光源，用于在所述第二光链路上提供第二光信号，所述第二光信号在与所述第一方向相反的第二方向上传播，其中所述拉曼泵响应于所述控制信号被禁用。

3. 发明申请

US20060073102A1 Abuse-resistant opioid solid dosage form 审中-公开
标题翻译：滥用阿片类固体剂型
公开(公告)号：US20060073102A1
公开(公告)日：2006-04-06
申请号：US10514387
申请日：2003-05-13
申请人： Kao Huaihung , Bradley Galer , David Kerr
发明人： Kao Huaihung , Bradley Galer , David Kerr
IPC分类号： A61K9/44
CPC分类号： A61K45/06 , A61K9/2081 , A61K31/485 , A61K2300/00
摘要： The present invention pertains to a solid dosage form comprising an analgesically effective amount of opioid analgesic and an opioid abuse-deterring amount of a nontoxic N-methyl-D-aspartate receptor antagonist contained in a carrier which isolates, or separates, the antagonist from the opioid analgesic. The nontoxic N-methyl-D-aspartate receptor antagonist is released and made available only when the dosage form is misused, as would be the case when the dosage form is crushed or dissolved and thereafter administered in a manner other than that indicated, e.g., by injection or intranasally.
摘要翻译：本发明涉及一种固体剂型，其包含镇痛有效量的阿片类止痛剂和阿片样物质滥用 - 限制剂量的载体中含有的无毒N-甲基-D-天冬氨酸受体拮抗剂，其将拮抗剂与阿片类止痛药。无毒的N-甲基-D-天冬氨酸受体拮抗剂被释放，并且仅当剂型被滥用时才能使用，如在剂型被粉碎或溶解的情况下，然后以不同于所指示的方式给药，通过注射或鼻内。

4. 发明申请

US20140309183A1 Low-Dose Combination Chemotherapy 审中-公开
标题翻译：低剂量联合化疗
公开(公告)号：US20140309183A1
公开(公告)日：2014-10-16
申请号：US14240660
申请日：2011-08-24
申请人： David Kerr
发明人： David Kerr
IPC分类号： A61K31/7068 , A61K45/06 , A61K31/675 , A61K31/704 , A61K31/506 , A61K31/282
CPC分类号： A61K31/7068 , A61K31/00 , A61K31/166 , A61K31/282 , A61K31/506 , A61K31/555 , A61K31/675 , A61K31/704 , A61K45/06 , A61K2300/00
摘要： Disclosed herein are compositions comprising at least two compounds in a therapeutically effective composition for treating cancer. Compositions include a single oral dosage form comprising at least two anti-cancer compounds. Also disclosed herein are methods of making and using such compositions.
摘要翻译：本文公开了包含用于治疗癌症的治疗有效组合物中的至少两种化合物的组合物。组合物包括包含至少两种抗癌化合物的单一口服剂型。本文还公开了制备和使用这些组合物的方法。

5. 发明申请

US20060000700A1 Switch contacts 审中-公开
标题翻译：切换联系人
公开(公告)号：US20060000700A1
公开(公告)日：2006-01-05
申请号：US11104358
申请日：2005-04-12
申请人： David Kerr
发明人： David Kerr
IPC分类号： H01H5/00
CPC分类号： H01H1/2025 , H01H9/40
摘要： A switch contact block assembly has a plurality of stationary contact pairs, a contact carriage carrying movably therewith a plurality of bridge contacts, positioned to make or break contact with the stationary contact pairs, according to a position of the contact carriage, and wherein the contact carriage is guided for rectilinear sliding movement, and wherein the plurality of bridge contacts have a substantially fixed positional relationship with one another whereby a making and a breaking of the contacts occurs substantially simultaneously.
摘要翻译：开关接触块组件具有多个固定触点对，一个接触托架，其可移动地承载多个桥接触头，该多个桥接触头根据接触托架的位置被定位成与固定触点对形成或断开接触，并且其中触点托架被引导用于直线滑动运动，并且其中多个桥接器彼此具有基本上固定的位置关系，从而基本上同时发生接触的产生和断裂。

6. 发明授权

US06625280B1 Balanced heat coil protector 有权
标题翻译：平衡热线圈保护器
公开(公告)号：US06625280B1
公开(公告)日：2003-09-23
申请号：US09431727
申请日：1999-11-01
申请人： David Kerr , Walter Pelosi , Mikhail Sumetskiy
发明人： David Kerr , Walter Pelosi , Mikhail Sumetskiy
IPC分类号： H04M100
CPC分类号： H01H79/00 , H01H71/122 , H04M3/18
摘要： A balanced heat coil protector protects telecommunications equipment from excessive sneak currents through a telecommunications circuit having a ring conductor and a tip conductor. An electrically conductive grounding pin is supported within and extends through the base for providing a path to ground potential. A first electrically conductive line pin and a first electrically conductive central office pin are supported in the base and extend therethrough, the first line pin and first central office pin being electrically connected to each other by a first conductive wire to provide a normal circuit current path from the first line pin to the first central office pin. A second electrically conductive line pin and a second electrically conductive central office pin are also supported in the base and extend therethrough, the second line pin and second central office pin being electrically connected to each other by a second conductive wire to provide a normal circuit current path from the second line pin to the second central office pin. A sleeve having electrically conductive flanged end portions is supported in an initial position within the housing on the grounding pin by a fusible material and is disposed above at least one of the first line and central office pins and at least one of the second line and central office pins, and the first and second conductive wires are wound about an outer surface of the sleeve. The fusible material melts in response to an excessive sneak current in either the ring or tip conductors causing the sleeve to move from the initial position to a grounding position in contact with at least one of the first line and central office pins and at least one of the second line and central office pins to simultaneously ground the ring and tip conductors.
摘要翻译：平衡热线圈保护器通过具有环形导体和尖端导体的电信电路来保护电信设备免受过度的潜行电流的影响。导电接地销被支撑在基座内并延伸穿过基座，以提供接地电位的路径。第一导电线销和第一导电中心办公室销被支撑在基座中并延伸穿过其中，第一线销和第一中心局销通过第一导线彼此电连接以提供正常的电路电流路径从第一行针到第一个中央办公室针。第二导电线销和第二导电中心局销也支撑在基座中并延伸穿过其中，第二线路引脚和第二中心局引脚通过第二导线彼此电连接以提供正常的电路电流从第二行引脚到第二个中心局引脚的路径。具有导电的法兰端部的套筒通过可熔材料被支撑在壳体内的接地销的壳体内的初始位置，并且设置在第一线路和中央办公室引脚中的至少一个上方，并且第二线路和中心线路中的至少一个办公室销，并且第一和第二导线围绕套筒的外表面缠绕。可熔材料响应于环形或尖端导体中的过度潜行电流而熔化，导致套筒从初始位置移动到与第一线路和中心办公插销中的至少一个接触的接地位置，并且至少一个第二线和中央办公室针脚同时接地环和尖端导体。

7. 发明授权

US5269879A Method of etching vias without sputtering of underlying electrically conductive layer 失效
标题翻译：蚀刻通孔而不溅射底层导电层的方法
公开(公告)号：US5269879A
公开(公告)日：1993-12-14
申请号：US777611
申请日：1991-10-16
申请人： Paul Rhoades , Mark Halman , David Kerr
发明人： Paul Rhoades , Mark Halman , David Kerr
IPC分类号： H01L21/311 , H01L21/768 , H01L21/00
CPC分类号： H01L21/76802 , H01L21/31116
摘要： A process for etching of silicon oxide/nitride such as silicon dioxide, silicon nitride or oxynitride. The process includes etching a silicon oxide/nitride layer to expose an underlying electrically conductive layer and provide a via extending through the silicon oxide/nitride layer to the electrically conductive layer. The etching is performed by exposing the silicon oxide/nitride layer to an etching gas in an ionized state in a reaction chamber of a plasma generating device. The etching gas includes a fluoride-containing gas and a passivating gas which is present in an amount effective to suppress sputtering of the electrically conductive layer when it is exposed to the etching gas during the etching step. The passivating gas can be nitrogen gas and the fluoride-containing gas can be CF.sub.4, CHF.sub.3, C.sub.2 F.sub.6, CH.sub.2 F.sub.2, SF.sub.6, other Freons and mixtures thereof. The etching gas can also include a carrier gas such as Ar, He, Ne, Kr or mixtures thereof. The etching can be reactive ion etching or plasma etching and the etching gas can be exposed to a microwave electric field and/or a magnetic field during the etching step. The etching gas can achieve 350% overetching while preventing sputtering of the electrically conductive layer which can be Al, Al alloys, Ti, TiN, TiW and Mo.
摘要翻译：氧化硅/氮化物如二氧化硅，氮化硅或氧氮化物的蚀刻方法。该方法包括蚀刻氧化硅/氮化物层以暴露下面的导电层，并提供穿过氧化硅/氮化物层延伸到导电层的通孔。通过在等离子体产生装置的反应室中将氧化硅/氮化物层以离子化状态的蚀刻气体曝光来进行蚀刻。蚀刻气体包括含氟化物气体和钝化气体，其在蚀刻步骤中暴露于蚀刻气体时有效地抑制导电层的溅射。钝化气体可以是氮气，含氟化物气体可以是CF4，CHF3，C2F6，CH2F2，SF6，其他氟利昂及其混合物。蚀刻气体还可以包括载气如Ar，He，Ne，Kr或其混合物。蚀刻可以是反应离子蚀刻或等离子体蚀刻，并且蚀刻气体可以在蚀刻步骤期间暴露于微波电场和/或磁场。蚀刻气体可以防止可以为Al，Al合金，Ti，TiN，TiW和Mo的导电层的溅射，达到350％的过蚀刻。

8. 发明授权

US5048964A Phase-stepping interferometry 失效
标题翻译：相位干涉测量
公开(公告)号：US5048964A
公开(公告)日：1991-09-17
申请号：US469480
申请日：1990-04-11
申请人： John R. Tyrer , Fernando Mendoza-Santoyo , David Kerr
发明人： John R. Tyrer , Fernando Mendoza-Santoyo , David Kerr
IPC分类号： G01B9/02 , G01B9/021 , G01J9/02
CPC分类号： G01B9/0201 , G01B9/02094
摘要： An interferometric procedure, such as electronic speckle pattern interferometry, involves generating two signals representing the point-by-point variations in intensity of respective patterns of electromagnetic radiation resulting from the interference of first and second beams of such radiation derived from a coherent source, with at least the first beam from each pattern being scattered, before interference with its respective second beam, from a common object surface, and with a corresponding pair of the beams, one for each pattern, having a predetermined relative phase difference of other than a multiple of .pi.; and determining from the two signals values for a datum phase of the radiation at the object surface. Preferably, as a preliminary to this last determination. DC components are removed from the two signals. Conveniently, to simplify the determination, the phase difference is an odd multiple of .pi./4 or .pi./2.
摘要翻译： PCT No.PCT / GB89 / 01030 Sec。 371日期1990年04月11日 102（e）1990年4月11日PCT PCT 1989年9月4日PCT公布。出版物WO90 / 02930 日期1990年3月22日。干涉测量程序，例如电子散斑图案干涉测量，涉及产生两个信号，表示由这种辐射的第一和第二波束的干涉导致的各种电磁辐射模式的逐点变化的信号衍生自相干光源，至少来自每个图案的第一光束在与其相应的第二光束干涉之前，从公共物体表面散射，并且与对应的一对光束一一对应于每个图案，具有预定的相对相位差不同于pi的倍数; 并根据两个信号确定物体表面上的辐射的基准相位值。优选地，作为该最后确定的初步。从两个信号中去除直流分量。方便地，为了简化确定，相位差是pi / 4或pi / 2的奇数倍。

9. 发明申请

US20100018941A1 METHOD AND APPARATUS FOR VERIFYING SEAL INTEGRITY 审中-公开
标题翻译：验证密封完整性的方法和装置
公开(公告)号：US20100018941A1
公开(公告)日：2010-01-28
申请号：US11721663
申请日：2005-12-14
申请人： David Kerr , Robert Parkin , Michael Jackson , Neil Brown , Fangmin Shi
发明人： David Kerr , Robert Parkin , Michael Jackson , Neil Brown , Fangmin Shi
IPC分类号： B65D41/00 , H04N7/18
CPC分类号： G01M3/38
摘要： A method of verifying the integrity of a seal in a sealing region between a container and a sealing film applied to the container comprises viewing at least the sealing region to detect the presence of a detectable predetermined feature in the sealing region. The presence of the detectable predetermined feature in the sealing region is indicative of an improper seal between the container and the sealing film whilst the absence of the detectable predetermined feature in the sealing region is indicative of an integral seal between the container and the sealing film.
摘要翻译：验证在容器和施加到容器上的密封膜之间的密封区域中密封件的完整性的方法包括至少观察密封区域以检测密封区域中可检测到的预定特征的存在。密封区域中可检测的预定特征的存在表示容器和密封膜之间的不正确的密封，而在密封区域中不存在可检测的预定特征指示容器和密封膜之间的整体密封。

10. 发明授权

US07091332B1 Treatment of staphylococcus infections 有权
标题翻译：葡萄球菌感染的治疗
公开(公告)号：US07091332B1
公开(公告)日：2006-08-15
申请号：US09698579
申请日：2000-10-27
申请人： A. John Bramley , Karen I. Plaut , David Kerr
发明人： A. John Bramley , Karen I. Plaut , David Kerr
IPC分类号： C07H21/04
CPC分类号： C12N9/52 , A61K48/00 , C12N15/86 , C12N2710/10343
摘要： The present invention relates to an improved approach for the treatment of microbial infections in mammals. Specifically, the invention provides methods and reagents for expressing in mammalian cells proteins that have anti-microbial activity. The invention provides both genes which have been modified to allow expression and preferably secretion of active protein in desired mammalian cells or tissues, and methods of introducing such modified genes into desired mammalian cells and/or tissues. Most specifically, genes encode anti-staphylococcal proteins are delivered to mammalian cells and/or tissues by methods of gene delivery, including gene therapy and the production of transgenic animals, for the treatment of mastitis in ruminant animals.
摘要翻译：本发明涉及用于治疗哺乳动物微生物感染的改进方法。具体地，本发明提供用于在哺乳动物细胞中表达具有抗微生物活性的蛋白质的方法和试剂。本发明提供了已被修饰以允许在期望的哺乳动物细胞或组织中表达和优选分泌活性蛋白质的两个基因，以及将这些修饰的基因导入所需的哺乳动物细胞和/或组织的方法。最具体地，编码抗葡萄球菌蛋白的基因通过基因递送方法（包括基因治疗和转基因动物的产生）被递送到哺乳动物细胞和/或组织，用于治疗反刍动物的乳腺炎。

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