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1. 发明授权

US5928264A Tissue grasping device 失效
标题翻译：组织抓握装置
公开(公告)号：US5928264A
公开(公告)日：1999-07-27
申请号：US904807
申请日：1997-08-01
申请人： David J. Sugarbaker , Andy H. Levine , Nicholas F. Warner , Eric E. May , Lawrence Crainich
发明人： David J. Sugarbaker , Andy H. Levine , Nicholas F. Warner , Eric E. May , Lawrence Crainich
IPC分类号： A61B17/00 , A61B17/28
CPC分类号： A61B17/00234 , A61B17/29 , A61B2017/2923 , A61B2017/2944
摘要： A tissue grasping device is disclosed having a distal end and a proximal end and a central axis extending from end to end. Three tissue engaging tines are located at the distal end, two of which are rotatable, and one of which is spaced from the other two and slidable lengthwise of the plicator. The tines are parallel to one another and to the main axis of the plicator. Actuating mechanism in the form of rack and pinion mechanisms rotate the rotatable tines relative to one another, to grip a portion of the tissue. The non-rotatable times space the portion of the tissue being operated on from the rotatable tine. A push-pull knob mechanism or a thumb-operated lever is employed at the proximal end of the plicator to slide the non-rotatable tine lengthwise of the device to position it in and out of its operating position.
摘要翻译：公开了具有远端和近端以及从端到端延伸的中心轴线的组织夹持装置。三个组织接合尖齿位于远端，其中两个是可旋转的，其中一个与另一个间隔开，并且可以在校准器的纵向方向上滑动。尖齿彼此平行并且与调节器的主轴平行。齿条和小齿轮机构形式的致动机构相对于彼此旋转可旋转齿，以夹持组织的一部分。不可旋转的时间使得从可旋转齿操作的组织的部分空间。在调节器的近端使用推拉旋钮机构或拇指操纵的杆，以使装置的纵向方向滑动不可旋转的定位器，以将其定位在其操作位置之外。

2. 发明授权

US5722990A Tissue grasping device 失效
标题翻译：组织抓握装置
公开(公告)号：US5722990A
公开(公告)日：1998-03-03
申请号：US558951
申请日：1995-11-13
申请人： David J. Sugarbaker , Andy H. Levine , Nicholas F. Warner , Eric E. May , Lawrence Crainich
发明人： David J. Sugarbaker , Andy H. Levine , Nicholas F. Warner , Eric E. May , Lawrence Crainich
IPC分类号： A61B17/00 , A61B17/28 , A61B19/00
CPC分类号： A61B17/00234 , A61B17/29 , A61B2017/2923 , A61B2017/2944
摘要： A tissue grasping device is disclosed having a distal end and a proximal end and a central axis extending from end to end. Three tissue engaging tines are located at the distal end, two of which are rotatable, and one of which is spaced from the other two and slidable lengthwise of the plicator. The tines are parallel to one another and to the main axis of the plicator. An actuating mechanism in the form of a rack and pinion mechanism rotate the rotatable tines relative to one another, to grip a portion of the tissue. The non-rotatable tines space the portion of the tissue being operated on from the rotatable tine. A knob mechanism is employed at the proximal end of the plicator to slide the non-rotatable tine lengthwise of the device to position it in and out of its operating position.
摘要翻译：公开了具有远端和近端以及从端到端延伸的中心轴线的组织夹持装置。三个组织接合尖齿位于远端，其中两个是可旋转的，其中一个与另一个间隔开，并且可以在校准器的纵向方向上滑动。尖齿彼此平行并且与调节器的主轴平行。齿条和小齿轮机构形式的致动机构相对于彼此旋转可旋转齿，以夹紧组织的一部分。不可旋转的齿可以从可旋转的齿处使得正在操作的组织的部分空间。在校准器的近端使用旋钮机构，以使装置的纵向方向滑动不可旋转的齿，以将其定位在其操作位置之外。

3. 发明授权

US5891162A Expanding polygonal surgical compressor 失效
标题翻译：扩大多边形手术压缩机
公开(公告)号：US5891162A
公开(公告)日：1999-04-06
申请号：US864778
申请日：1997-05-29
申请人： David J. Sugarbaker , Andy H. Levine , Philip R. Lichtman , John C. Meade
发明人： David J. Sugarbaker , Andy H. Levine , Philip R. Lichtman , John C. Meade
IPC分类号： A61B17/02 , A61B17/28
CPC分类号： A61B17/29 , A61B2017/0243 , A61B2017/2926 , A61B2017/2937 , A61B2017/2939
摘要： An expanding polygonal surgical compressor has a first planar frame with at least three articulated frame members extendable from a compressed configuration to an extended configuration forming a polygon. A second planar frame has frame members corresponding to the frame members of the first frame. The first and second frames are pivoted relative to each other for movement from an open to a closed or tissue compressing position.
摘要翻译：扩展的多边形手术压缩机具有第一平面框架，其具有至少三个铰接框架构件，其从压缩构造延伸到形成多边形的延伸构造。第二平面框架具有对应于第一框架的框架构件的框架构件。第一和第二框架相对于彼此枢转以从开放到封闭或组织压缩位置的运动。

4. 发明授权

US07318814B2 Medical suction valve 有权
标题翻译：医用吸入阀
公开(公告)号：US07318814B2
公开(公告)日：2008-01-15
申请号：US10216974
申请日：2002-08-12
申请人： Andy H. Levine , Eric E. May , Anthony R. Tremaglio
发明人： Andy H. Levine , Eric E. May , Anthony R. Tremaglio
IPC分类号： A61M1/00
CPC分类号： A61B1/00195 , A61B1/00135 , A61B1/12 , A61B90/361 , A61B2017/2927 , A61B2017/3445 , A61M1/0035 , A61M1/0043 , A61M1/0064 , F16K3/262
摘要： A valve assembly includes a housing defining an aperture, a passageway, and a branch passage. The branch passage extends from the aperture and intersects and communicates with the passageway. The branch passage is disposed at an angle greater than 90 degrees with respect to the passageway. A piston is disposed at least partially within the branch passage and is movable from a first position to a second position. The piston allows communication between the passageway and the aperture when the piston is in the first position, and the piston blocks communication between the passageway and the aperture when the piston is in the second position. An angled seal may be positioned around the piston.
摘要翻译：阀组件包括限定孔的壳体，通道和分支通道。分支通道从孔径延伸并与通道相交并连通。分支通道相对于通道以大于90度的角度设置。活塞至少部分地设置在分支通道内，并且可从第一位置移动到第二位置。当活塞处于第一位置时，活塞允许通道和孔之间的连通，并且当活塞处于第二位置时活塞阻挡通道和孔之间的连通。角度密封件可以围绕活塞定位。

5. 发明申请

US20130012862A1 METHODS AND APPARATUS FOR ANCHORING WITHIN THE GASTROINTESTINAL TRACT 有权
公开(公告)号：US20130012862A1
公开(公告)日：2013-01-10
申请号：US13618036
申请日：2012-09-14
申请人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
发明人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.

6. 发明授权

US08303669B2 Methods and apparatus for anchoring within the gastrointestinal tract 有权
标题翻译：在胃肠道内锚定的方法和装置
公开(公告)号：US08303669B2
公开(公告)日：2012-11-06
申请号：US12880631
申请日：2010-09-13
申请人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
发明人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
IPC分类号： A61F2/04 , A61F11/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.
摘要翻译：本发明涉及一种被配置用于微创植入并被设计成保持牢固地定位在动物的胃肠道的至少一部分内的锚。锚固件包括由围绕中心轴成形为环形波浪图案的细长弹性构件形成的径向弹簧。锚固件限定了中心腔并且提供向外的径向力，同时允许围绕其周边的实质弯曲。锚固件通常是可移除的，但是可以包括紧固件，例如倒钩，以进一步将其固定到周围的解剖结构。在一些实施例中，锚固件包括将固定部分连接到可移除部分的连接器。此外，锚可用于将医疗装置固定在体内，例如肠内的柔性套管。

7. 发明授权

US08096966B2 Eversion resistant sleeves 有权
标题翻译：防翻转袖子
公开(公告)号：US08096966B2
公开(公告)日：2012-01-17
申请号：US12819605
申请日：2010-06-21
申请人： Andy H. Levine , David A. Melanson , Ian Parker
发明人： Andy H. Levine , David A. Melanson , Ian Parker
IPC分类号： A61M5/00
CPC分类号： A61F2/04 , A61F5/0076 , A61F2002/044 , A61F2250/0018 , A61F2250/0039
摘要： The invention relates to improved means for preventing eversion and subsequent obstruction of thin-walled, floppy gastrointestinal liners implanted in the digestive tract of an animal. The implantable devices include an anchor adapted for attachment within a natural body lumen and a thin-walled, floppy sleeve open at both ends and defining a lumen therebetween. A substantial length of the sleeve has material characteristics that result in the sleeve being prone to eversion in the presence of retrograde pressures. Exemplary eversion-resistant features provide an increased stiffness and/or an increased friction coefficient between the anchor and the proximal end of the sleeve to resist eversion. In some embodiments, the eversion-resistant feature includes an anti-buckling element, such as a wire coupled along the substantial length of the sleeve.
摘要翻译：本发明涉及用于防止植入动物消化道的薄壁软盘胃肠衬垫的外翻和随后阻塞的改进方法。可植入装置包括适于附接在天然体腔内的锚固体和在两端开口并在其间限定内腔的薄壁软盘。套筒的相当长度具有导致在存在逆向压力的情况下套筒易于外翻的材料特性。示例性的抗外翻特征提供了在套筒的锚固件和近端之间增加的刚度和/或增加的摩擦系数以抵抗外翻。在一些实施例中，抗外壳特征包括抗弯曲元件，例如沿着套筒的大部分长度连接的线。

8. 发明申请

US20110245752A1 METHODS OF TREATMENT USING A BARIATRIC SLEEVE 有权
标题翻译：使用BARIATRIC SLEEVE治疗方法
公开(公告)号：US20110245752A1
公开(公告)日：2011-10-06
申请号：US13098750
申请日：2011-05-02
申请人： Andy H. Levine , David A. Melanson
发明人： Andy H. Levine , David A. Melanson
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/0084 , A61B2017/00867 , A61B2017/0419 , A61B2017/06052 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2210/0076 , A61F2220/0016 , A61F2250/0039
摘要： Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.
摘要翻译：介绍了限制消化系统特定部位食品吸收的方法和装置。胃肠道植入装置锚定在胃中并延伸超过Treitz的韧带。所有离开胃的食物都通过设备进行漏斗。胃肠装置包括用于将装置固定到胃的锚固件和柔性套管，以限制十二指肠中的营养物质的吸收。锚固体可折叠用于内窥镜递送和移除。

9. 发明申请

US20110004230A1 Atraumatic Gastrointestinal Anchor 审中-公开
标题翻译：无创胃肠锚
公开(公告)号：US20110004230A1
公开(公告)日：2011-01-06
申请号：US12882606
申请日：2010-09-15
申请人： Andy H. Levine , John C. Meade , David A. Melanson
发明人： Andy H. Levine , John C. Meade , David A. Melanson
IPC分类号： A61B17/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/045 , A61F2002/072 , A61F2002/075 , A61F2002/828 , A61F2002/8483 , A61F2002/9534 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2250/0036 , A61F2250/0037
摘要： The present invention relates to methods and articles for anchoring within a natural bodily lumen. An anchor is adapted to provide differing radially-outward forces along its length, a securing force and a transitional force. Production of these forces can be controlled by varying a physical property of the anchor, such as its stiffness, thickness, or shape. For example, the stiffness of an elongated anchor can be varied from a relatively soft value at its proximal and distal ends to a relatively stiff value at its center by varying the diameter of wire forming the anchor, thereby tailoring it to an intended application. Such force tailoring can be combined with external barbs and used to reliably anchor other instruments, such as feeding tubes and intestinal sleeves.
摘要翻译：本发明涉及用于锚定在天然体腔内的方法和制品。锚固件适于沿其长度提供不同的径向向外的力，固定力和过渡力。可以通过改变锚的物理性质来控制这些力的产生，例如其刚度，厚度或形状。例如，细长锚固件的刚度可以从其近端和远端处的相对软的值变化到其中心处的相对刚性值，通过改变形成锚固件的线的直径，从而将其定制到预期应用。这种力量裁剪可以与外部倒钩相结合，用于可靠地锚定其他器械，如饲管和肠衣。

10. 发明授权

US07815589B2 Methods and apparatus for anchoring within the gastrointestinal tract 有权
标题翻译：在胃肠道内锚定的方法和装置
公开(公告)号：US07815589B2
公开(公告)日：2010-10-19
申请号：US10858852
申请日：2004-06-01
申请人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
发明人： John C. Meade , Andy H. Levine , David A. Melanson , John F. Cvinar
IPC分类号： A61M5/00 , A61F2/04
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.
摘要翻译：本发明涉及一种被配置用于微创植入并被设计成保持牢固地定位在动物的胃肠道的至少一部分内的锚。锚固件包括由围绕中心轴成形为环形波浪图案的细长弹性构件形成的径向弹簧。锚固件限定了中心腔并且提供向外的径向力，同时允许围绕其周边的实质弯曲。锚固件通常是可移除的，但是可以包括紧固件，例如倒钩，以进一步将其固定到周围的解剖结构。在一些实施例中，锚固件包括将固定部分连接到可移除部分的连接器。此外，锚可用于将医疗装置固定在体内，例如肠内的柔性套管。

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