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1. 发明授权

US06309343B1 Method for making an ePTFE graft-stent composite device 有权
标题翻译：制造ePTFE移植物支架复合器件的方法
公开(公告)号：US06309343B1
公开(公告)日：2001-10-30
申请号：US09324303
申请日：1999-06-02
申请人： David J. Lentz , Edward Dormier
发明人： David J. Lentz , Edward Dormier
IPC分类号： A61F204
CPC分类号： A61F2/07 , A61F2/92 , A61F2002/072 , A61F2002/075 , Y10S623/901 , Y10S623/909
摘要： An implantable intraluminal device includes a multilayer composite tubular device supporting one or more stents between the layer thereof and a method of making such a device is disclosed. A first porous elongate tube includes an exterior surface and an interior luminal surface. A radially expandable member is disposed about the exterior surface of the first tube. A second porous elongate tube is disposed concentrically over the first tube and is secured thereto so that the radially expandable member is longitudinally immobilized therebetween.
摘要翻译：一种可植入管腔内装置包括一层支撑一层或多层支架的多层复合管状装置，其中公开了制造这种装置的方法。第一多孔细长管包括外表面和内腔内表面。径向可扩张构件围绕第一管的外表面设置。第二多孔细长管同心地设置在第一管上方并且被固定到其上，使得可径向扩张的构件在其间纵向固定。

2. 发明授权

US08083790B2 ePTFE graft-stent composite device 失效
标题翻译： ePTFE移植支架复合装置
公开(公告)号：US08083790B2
公开(公告)日：2011-12-27
申请号：US11392461
申请日：2006-03-29
申请人： David J. Lentz , Edward Dormier
发明人： David J. Lentz , Edward Dormier
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/92 , A61F2002/072 , A61F2002/075 , Y10S623/901 , Y10S623/909
摘要： An implantable intraluminal device includes a multilayer composite tubular device supporting one or more stents between the layer thereof. A first porous elongate tube includes an exterior surface and an interior luminal surface. A radially expandable member is disposed about the exterior surface of the first tube. A second porous elongate tube is disposed concentrically over the first tube and is secured thereto so that the radially expandable member is longitudinally immobilized therebetween.
摘要翻译：可植入管腔内装置包括在其层之间支撑一个或多个支架的多层复合管状装置。第一多孔细长管包括外表面和内腔内表面。径向可扩张构件围绕第一管的外表面设置。第二多孔细长管同心地设置在第一管上方并且被固定到其上，使得可径向扩张的构件在其间纵向固定。

3. 发明授权

US5961545A EPTFE graft-stent composite device 失效
标题翻译： EPTFE移植支架复合装置
公开(公告)号：US5961545A
公开(公告)日：1999-10-05
申请号：US784842
申请日：1997-01-17
申请人： David J. Lentz , Edward Dormier
发明人： David J. Lentz , Edward Dormier
IPC分类号： A61F2/92 , A61F2/06
CPC分类号： A61F2/07 , A61F2/92 , A61F2002/072 , A61F2002/075 , Y10S623/901 , Y10S623/909
摘要： An implantable intraluminal device includes a multilayer composite tubular device supporting one or more stents between the layer thereof. A first porous elongate tube includes an exterior surface and an interior luminal surface. A radially expandable member is disposed about the exterior surface of the first tube. A second porous elongate tube is disposed concentrically over the first tube and is secured thereto so that the radially expandable member is longitudinally immobilized therebetween.
摘要翻译：可植入管腔内装置包括在其层之间支撑一个或多个支架的多层复合管状装置。第一多孔细长管包括外表面和内腔内表面。径向可扩张构件围绕第一管的外表面设置。第二多孔细长管同心地设置在第一管上方并且被固定到其上，使得可径向扩张的构件在其间纵向固定。

4. 发明授权

US5843166A Composite graft-stent having pockets for accomodating movement 失效
标题翻译：复合移植支架具有用于容纳运动的口袋
公开(公告)号：US5843166A
公开(公告)日：1998-12-01
申请号：US784843
申请日：1997-01-17
申请人： David J. Lentz , Edward Dormier
发明人： David J. Lentz , Edward Dormier
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/072
摘要： An implantable intraluminal device includes a first porous elongate tube with first and second opposed ends and an exterior surface and an interior luminal surface. A radially expandable member is disposed about the exterior surface of the first tube. A second porous elongate tube is disposed concentrically over the first tube and the radially expandable member and is secured to the first tube so that the radially expandable member is transversely mobile within a pocket formed by the securement of the first tube to the second tube.
摘要翻译：可植入管腔内装置包括具有第一和第二相对端的第一多孔细长管和外表面和内部腔表面。径向可扩张构件围绕第一管的外表面设置。第二多孔细长管同心地设置在第一管和径向可扩张构件上并且被固定到第一管，使得可径向扩张的构件在通过将第一管固定到第二管形成的口袋内横向移动。

5. 发明授权

US07044961B2 ePTFE graft-stent composite device 失效
公开(公告)号：US07044961B2
公开(公告)日：2006-05-16
申请号：US09957964
申请日：2001-09-21
申请人： David J. Lentz , Edward Dormier
发明人： David J. Lentz , Edward Dormier
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/92 , A61F2002/072 , A61F2002/075 , Y10S623/901 , Y10S623/909
摘要： An implantable intraluminal device includes a multilayer composite tubular device supporting one or more stents between the layer thereof. A first porous elongate tube includes an exterior surface and an interior luminal surface. A radially expandable member is disposed about the exterior surface of the first tube. A second porous elongate tube is disposed concentrically over the first tube and is secured thereto so that the radially expandable member is longitudinally immobilized therebetween.

6. 发明授权

US08377050B2 Cryo-applicator cross-section configuration 有权
标题翻译：冷冻设备横截面配置
公开(公告)号：US08377050B2
公开(公告)日：2013-02-19
申请号：US11760564
申请日：2007-06-08
申请人： David J. Lentz , Jillian K. Allen
发明人： David J. Lentz , Jillian K. Allen
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/003 , A61B2018/0212 , A61B2018/0262
摘要： A configuration for a cryo-catheter which optimizes both the catheter's outer diameter and the size of the catheter's internal refrigerant flow path is described. Specifically, the inner dimensions of the cryo-catheter are configured to accommodate a pre-selected flow of refrigerant into the catheter's distal tip, and a return flow of refrigerant from the distal tip. The return flow is established in the void spaces between a refrigerant supply line and the inner wall of the catheter body. The available void space varies along the catheter length and depends on the presence/absence of various catheter accessories (i.e. pull wires, pressure tubes, etc.) which typically only extend through a portion of the catheter length. The disclosed configuration ensures that the cryo-catheter does not operate in a refrigerant limited condition, maintains the refrigerant as a liquid in the supply tube, and maintains the return line pressure at about 1 atmosphere.
摘要翻译：描述了优化导管的外径和导管的内部制冷剂流动路径的尺寸的低温导管的配置。具体地，冷冻导管的内部尺寸被配置为容纳预先选择的制冷剂流入导管的远侧末端，以及来自远侧末端的制冷剂回流。在制冷剂供应管线和导管体的内壁之间的空隙空间中建立回流。可用的空隙空间沿着导管长度而变化，并且取决于通常仅延伸穿过导管长度的一部分的各种导管配件（即拉线，压力管等）的存在/不存在。所公开的配置确保冷冻导管不在制冷剂限制条件下操作，将制冷剂保持为供应管中的液体，并将返回管线压力保持在大约1个大气压。

7. 发明授权

US08092444B2 Catheter articulation segment with alternating cuts 失效
标题翻译：导管交叉节段交替切割
公开(公告)号：US08092444B2
公开(公告)日：2012-01-10
申请号：US12642362
申请日：2009-12-18
申请人： David J. Lentz , Richard J. Koerner
发明人： David J. Lentz , Richard J. Koerner
IPC分类号： A61M25/00
CPC分类号： A61M25/0013 , A61M25/0054 , A61M25/0138
摘要： An articulation segment for a catheter includes a tube formed with a first plurality of axially aligned slits that are respectively oriented in planes perpendicular to the axis, with each slit extending azimuthally in an arc partway around the axis. The tube is also formed with a second plurality of similarly formed slits that are axially offset and diametrically opposed relative to the slits of the first plurality to allow for a bending of the catheter in a plurality of different planes. In a particular embodiment, the slits are arranged to allow the articulation segment to be reconfigured from a straight, substantially cylindrically shaped tube to a configuration in which a portion of the articulation segment is formed in the shape of a ring.
摘要翻译：用于导管的关节节段包括形成有第一多个轴向对准的狭缝的管，其分别定向在垂直于轴线的平面中，每个狭缝围绕轴线在一半弧中方位延伸。管还形成有第二多个类似形成的狭缝，其相对于第一多个的狭缝轴向地偏置并沿直径相对，以允许导管在多个不同平面中弯曲。在特定实施例中，狭缝被布置成允许关节运动部分从直的基本上圆柱形的管重新配置到其中关节节段的一部分形成为环形的构造。

8. 发明申请

US20080306475A1 CRYO-APPLICATOR CROSS-SECTION CONFIGURATION 有权
公开(公告)号：US20080306475A1
公开(公告)日：2008-12-11
申请号：US11760564
申请日：2007-06-08
申请人： David J. Lentz , Jillian K. Allen
发明人： David J. Lentz , Jillian K. Allen
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/003 , A61B2018/0212 , A61B2018/0262
摘要： A configuration for a cryo-catheter which optimizes both the catheter's outer diameter and the size of the catheter's internal refrigerant flow path is described. Specifically, the inner dimensions of the cryo-catheter are configured to accommodate a pre-selected flow of refrigerant into the catheter's distal tip, and a return flow of refrigerant from the distal tip. The return flow is established in the void spaces between a refrigerant supply line and the inner wall of the catheter body. The available void space varies along the catheter length and depends on the presence/absence of various catheter accessories (i.e. pull wires, pressure tubes, etc.) which typically only extend through a portion of the catheter length. The disclosed configuration ensures that the cryo-catheter does not operate in a refrigerant limited condition, maintains the refrigerant as a liquid in the supply tube, and maintains the return line pressure at about 1 atmosphere.
摘要翻译：描述了优化导管的外径和导管的内部制冷剂流动路径的尺寸的低温导管的配置。具体地，冷冻导管的内部尺寸被配置为容纳预先选择的制冷剂流入导管的远侧末端，以及来自远侧末端的制冷剂回流。在制冷剂供应管线和导管体的内壁之间的空隙空间中建立回流。可用的空隙空间沿着导管长度而变化，并且取决于通常仅延伸穿过导管长度的一部分的各种导管配件（即拉线，压力管等）的存在/不存在。所公开的配置确保冷冻导管不在制冷剂限制条件下操作，将制冷剂保持为供应管中的液体，并将返回管线压力保持在大约1个大气压。

9. 发明授权

US06306165B1 ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin 失效
标题翻译： ePTFE小口径血管移植物通过包含共价键合的肝素的表面涂层具有显着的通畅性增强
公开(公告)号：US06306165B1
公开(公告)日：2001-10-23
申请号：US08713800
申请日：1996-09-13
申请人： Birendra K. Patnaik , Horng-Ban Lin , David J. Lentz , Richard J. Zdrahala
发明人： Birendra K. Patnaik , Horng-Ban Lin , David J. Lentz , Richard J. Zdrahala
IPC分类号： A61F206
CPC分类号： A61L27/34 , A61L27/507 , A61L33/0029 , A61L33/0047 , A61L33/0094
摘要： Disclosed are implantable medical devices with enhanced patency. Expanded polytetrafluoroethylene small caliber vascular grafts coated with polymer bound bio-active agents that exhibit enhanced patency are disclosed. The polymer bound bio-active agents can include anti-thrombogenic agents, antibiotics, antibacterial agents and antiviral agents. Methods of preparing same are also provided.
摘要翻译：公开了具有增强的通畅的可植入医疗装置。公开了扩张聚四氟乙烯小口径血管移植物，其涂覆有聚合物结合的生物活性剂，其显示增强的通畅。聚合物结合的生物活性剂可以包括抗血栓形成剂，抗生素，抗菌剂和抗病毒剂。还提供了制备方法。

10. 发明授权

US6080198A Method for forming a yarn wrapped PTFE tubular prosthesis 失效
标题翻译：用于形成缠绕PTFE管状假体的纱线的方法
公开(公告)号：US6080198A
公开(公告)日：2000-06-27
申请号：US964414
申请日：1997-11-04
申请人： David J. Lentz , Nick Popadiuk , Peter Schmitt , Edward J. Dormier , Richard J. Zdrahala
发明人： David J. Lentz , Nick Popadiuk , Peter Schmitt , Edward J. Dormier , Richard J. Zdrahala
IPC分类号： A61L27/00 , A61F2/06 , A61L27/16 , A61L27/50
CPC分类号： A61F2/07 , A61F2/06 , A61F2/88 , A61L27/16 , A61L27/507 , A61F2002/072 , Y10S623/901
摘要： An implantable microporous ePTFE tubular vascular graft exhibits long-term patency, superior radial tensile strength, reduction in tear propagation, and increases in suture retention strength and crush resistance. The graft includes an ePTFE tubular structure having a preselected microporous structure. The tubular structure is wrapped externally with a PTFE yarn in a helical fashion. The helical wrap of yarn is bonded to the exterior surface of the tubular structure by application of heat or heat in combination with force to form a composite structure which substantially maintains the porosity of the underlying tubular structure while increasing the suture retention strength, radial tensile strength, crush resistance, and tear propagation resistance.
摘要翻译：可植入的微孔ePTFE管状血管移植物显示出长期通畅，优异的径向拉伸强度，撕裂增加的减少，以及缝线保持强度和抗压性的提高。移植物包括具有预选微孔结构的ePTFE管状结构。管状结构以螺旋方式用PTFE纱线外部包裹。通过结合施加热量或热量将纱线的螺旋卷绕结合到管状结构的外表面，以形成复合结构，其基本上保持下面的管状结构的孔隙率，同时增加缝合线保持强度，径向拉伸强度抗碎裂性和抗撕裂性。

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