专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20080146571A1 O-LINKED PYRIMIDIN-4-AMINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE TO TREAT CANCER 有权
标题翻译： O型连接的吡啶基-4-胺基化合物，包含它们的组合物及其用于治疗癌症的方法
公开(公告)号：US20080146571A1
公开(公告)日：2008-06-19
申请号：US11954433
申请日：2007-12-12
申请人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
发明人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
IPC分类号： A61K31/506 , C07D239/47 , C07D403/12 , A61K31/519 , A61P35/00 , A61K31/5377 , C07D491/044 , C07D413/12
CPC分类号： C07D401/12 , C07D401/14 , C07D409/14
摘要： O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:
摘要翻译：描述了O-连接的嘧啶-4-胺类化合物，包含它们的药物组合物及其使用方法。本发明的具体化合物具有式I：

2. 发明授权

US08093246B2 O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer 有权
标题翻译： O-连接的嘧啶-4-胺类化合物，包含它们的组合物及其用于治疗癌症的方法
公开(公告)号：US08093246B2
公开(公告)日：2012-01-10
申请号：US11954433
申请日：2007-12-12
申请人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
发明人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
IPC分类号： C07D403/14 , A61K31/506
CPC分类号： C07D401/12 , C07D401/14 , C07D409/14
摘要： O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:
摘要翻译：描述了O-连接的嘧啶-4-胺类化合物，包含它们的药物组合物及其使用方法。本发明的具体化合物具有式I：

3. 发明授权

US08093245B2 4-amino-1H-pyrimidin-2-one based compounds, compositions comprising them and methods of their use 有权
标题翻译： 4-氨基-1H-嘧啶-2-酮基化合物，包含它们的组合物及其使用方法
公开(公告)号：US08093245B2
公开(公告)日：2012-01-10
申请号：US11954421
申请日：2007-12-12
申请人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Alexander Heim-Riether , Theodore C. Jessop , James E. Tarver , Jerry A. Taylor
发明人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Alexander Heim-Riether , Theodore C. Jessop , James E. Tarver , Jerry A. Taylor
IPC分类号： C07D239/47 , C07D403/04 , A61K31/506
CPC分类号： C07D239/47 , C07D239/54 , C07D403/04 , C07D403/08 , C07D403/12 , C07D405/12 , C07D409/14 , C07D417/12 , C07D471/04
摘要： 4-Amino-1H-pyrimidin-2-one-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of various diseases and disorders are disclosed. Particular compounds are of formula I:
摘要翻译：公开了4-氨基-1H-嘧啶-2-酮基化合物，包含它们的组合物及其用于治疗，预防和治疗各种疾病和病症的方法。特定的化合物具有式I：

4. 发明申请

US20080182847A1 4-AMINO-1H-PYRIMIDIN-2-ONE BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE 有权
标题翻译： 4-氨基-1H-吡嗪二酮化合物，包含它们的组合物及其使用方法
公开(公告)号：US20080182847A1
公开(公告)日：2008-07-31
申请号：US11954421
申请日：2007-12-12
申请人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Alexander Heim-Riether , Theodore C. Jessop , James E. Tarver , Jerry A. Taylor
发明人： David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Alexander Heim-Riether , Theodore C. Jessop , James E. Tarver , Jerry A. Taylor
IPC分类号： A61K31/517 , A61K31/513 , C07D403/02
CPC分类号： C07D239/47 , C07D239/54 , C07D403/04 , C07D403/08 , C07D403/12 , C07D405/12 , C07D409/14 , C07D417/12 , C07D471/04
摘要： 4-Amino-1H-pyrimidin-2-one-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of various diseases and disorders are disclosed. Particular compounds are of formula I:
摘要翻译：公开了4-氨基-1H-嘧啶-2-酮基化合物，包含它们的组合物及其用于治疗，预防和治疗各种疾病和病症的方法。特定的化合物具有式I：

5. 发明授权

US4314788A Crop handling apparatus 失效
标题翻译：作物处理设备
公开(公告)号：US4314788A
公开(公告)日：1982-02-09
申请号：US114886
申请日：1980-01-24
申请人： Rodney B. Williams , Jerry A. Taylor
发明人： Rodney B. Williams , Jerry A. Taylor
IPC分类号： B65D88/62 , B65G65/23
CPC分类号： B65D88/62
摘要： An open-topped container is constructed with a plurality of compartments, each having its own discharge opening and each having its own liner of the type that can be selectively rolled up or unrolled according to loading and unloading operations. Each liner is connected to its own biasing means which is effective to yield and lower the liner as the compartment is loaded and effective to recover to elevate the liner to facilitate unloading, all for the purpose of handling material, such as fruits and vegetables and the like, in such a way as to eliminate or at least minimize damage thereto.
摘要翻译：顶部开口的容器被构造成具有多个隔室，每个隔间具有其自己的排出口，并且每个隔室具有其自身的可以根据装载和卸载操作选择性卷起或展开的衬垫。每个衬套连接到其自身的偏置装置，该隔板装载有效地产生和降低衬套，并且有效地恢复以提升衬垫以便于卸载，所有这些都用于处理诸如水果和蔬菜的材料，以及以这样的方式，以消除或至少最小化对其的损害。

6. 发明授权

US4721427A Wafer transfer stand 失效
标题翻译：晶圆转台
公开(公告)号：US4721427A
公开(公告)日：1988-01-26
申请号：US48868
申请日：1987-05-12
申请人： John D. Sanders , Jerry A. Taylor
发明人： John D. Sanders , Jerry A. Taylor
IPC分类号： H01L21/673 , B65G65/30
CPC分类号： H01L21/67781 , Y10S414/138
摘要： Empty wafer cassettes are stored on a transfer stand having one or more storage locations on a post which extends below a wafer comb while the wafers are being processed. Each storage location generally has a cross bar with spaced upward projections for receiving the leg of a cassette.
摘要翻译：空的晶片盒被存储在具有一个或多个存储位置的转印支架上，该柱位于在正在处理晶片的同时在晶片梳上延伸的柱上。每个存储位置通常具有横杆，其具有用于接收盒的腿的间隔开的向上突起。

7. 发明授权

US4185713A Hydrostatic drive system 失效
标题翻译：静液压驱动系统
公开(公告)号：US4185713A
公开(公告)日：1980-01-29
申请号：US877441
申请日：1978-02-13
申请人： Rodney B. Williams , Jerry A. Taylor
发明人： Rodney B. Williams , Jerry A. Taylor
IPC分类号： B60K17/10 , B60K17/14 , B60K17/356 , B62D49/06 , B60K17/34
CPC分类号： F16H61/444 , B60K17/10 , B60K17/14 , B60K17/356 , B62D49/0607
摘要： A hydrostatic drive system for a four wheel drive vehicle such as a field harvesting machine which must accurately track the planting rows, includes an engine, a pump and individual hydraulic wheel motors connected to the pump and coupled to the wheels through a manually set free wheeling clutch. The motors are in series connection at each side of the vehicle, with the pairs of series connected motors on opposite sides of the vehicle in parallel connection with the pump. When the traction of a wheel on one side is reduced or lost, both wheels on that side continue to rotate at the same speed. Under these conditions, the driving wheel motor on the aforesaid side of the vehicle will provide increased torque output to compensate for the reduced driving power of the slipping wheel. For road travel between harvesting fields, the wheels on the right side of the vehicle are mechanically declutched from their respective motors, and valves are closed to close off the hydraulic lines to the right side motors which routes all of the hydraulic fluid from the pump to the motors on the left side of the vehicle, and hence the ground speed of the vehicle in two wheel drive is approximately double the harvesting speed in four wheel drive for a given output of the hydraulic pump which drives the motors.
摘要翻译：用于四轮驱动车辆的静液压驱动系统，例如必须准确地跟踪种植行的田间收割机，包括发动机，泵和连接到泵并且通过手动设置的自由轮连接到车轮的单独的液压轮马达离合器。电动机在车辆的每一侧串联连接，车辆两侧的成对的串联电动机与泵并联连接。当一侧的车轮的牵引力减小或损失时，该侧的两个车轮以相同的速度继续旋转。在这些条件下，车辆上述侧的驱动轮马达将提供增加的扭矩输出以补偿滑轮的降低的驱动力。对于收割区域之间的道路行驶，车辆右侧的轮子从其各自的马达机械地离开，并且关闭阀门以将液压管线关闭到右侧马达，其将所有液压流体从泵路由到车轮左侧的电机，因此车轮在两轮驱动中的地面速度大约是用于驱动电动机的液压泵的给定输出的四轮驱动的收获速度的两倍。

8. 发明申请

US20190352294A1 Factor XIIa Inhibitors 审中-公开
公开(公告)号：US20190352294A1
公开(公告)日：2019-11-21
申请号：US16461849
申请日：2017-11-13
申请人： Ashwin RAO , Brian Alexander MCKITTRICK , Matthew LOMBARDO , Jacqueline D. HICKS , Amy Bittner MCCRACKEN , Hong Dong CHU , Sung-Sau SO , Peter ORTH , Zhicai WU , Ping LAN , John S. DEBENHAM , Brent R. WHITEHEAD , Jerry A. TAYLOR , Zhongxiang SUN , Revathi Reddy KATIPALLY , Jonathan E. GABLE , Markus K. DAHLGREN , Sathesh P. BHAT , Merck Sharp & Dohme Corp.
发明人： Ashwin U. Rao , Brian Alexander McKittrick , Matthew Lombardo , Jacqueline D. Hicks , Amy Bittner McCracken , Hong Dong Chu , Sung-Sau So , Peter Orth , Zhicai Wu , Ping Lan , John S. Debenham , Brent R. Whitehead , Jerry A. Taylor , Zhongxiang Sun , Revathi Reddy Katipally , Jonathan E. Gable , Markus K. Dahlgren , Sathesh P. Bhat
IPC分类号： C07D413/14 , C07D495/04 , A61P7/02
摘要： The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.

9. 发明授权

US4185696A Row crop harvester with adjustable picking heads 失效
标题翻译：行式收割机与可调拣选头
公开(公告)号：US4185696A
公开(公告)日：1980-01-29
申请号：US790355
申请日：1977-04-25
申请人： Rodney B. Williams , Jerry A. Taylor
发明人： Rodney B. Williams , Jerry A. Taylor
IPC分类号： A01D23/04 , A01D25/04 , A01D33/14 , A01D27/04
CPC分类号： A01D33/14 , A01D23/04 , A01D25/04
摘要： A row crop harvester is provided with mechanism for mounting two picking heads for both vertical and horizontal adjustment of the ground engaging lower ends of the heads, to simultaneously harvest two rows of plants which may vary in spacing from each other throughout their lengths. One head is guided along its row by steering the harvester itself, while the lower end of the other head is guided along its row by selectively operating controls which transversely shift the lower end of the head relative to the first mentioned steerable head thereby accurately following and simultaneously harvesting two rows of crops such as root crops.In the preferred embodiment the upper end of each picking head is associated with a severing mechanism for removing the tops or foliage from the roots of the plants. The severing mechanisms are mounted at fixed locations on the vehicle and are associated with foliage separating devices for allowing the roots of the row crops received from each picking head to be collected by a transverse conveyor-elevator while the severed tops are deflected to the ground by vine guards and associated platforms.
摘要翻译：一排作物收割机设置有用于安装两个采摘头的机构，用于垂直和水平调节头部接地下端的地面，以同时收获两排植物，这两个植物在整个长度上可以彼此间隔地变化。通过转向收割机本身来引导一个头部，同时另一个头部的下端通过选择性地操作控制器而被引导，该控制器使头部的下端相对于首先提到的可转向头横向移动，从而精确地跟随和同时收获两排作物，如根茎作物。在优选实施例中，每个拾取头的上端与用于从植物的根部移除顶部或叶子的切断机构相关联。切断机构安装在车辆上的固定位置处，并与叶片分离装置相关联，用于允许从每个采摘头接收的排作物的根部通过横向输送机 - 电梯收集，同时切断的顶部通过藤守卫和相关平台。

10. 发明授权

US3986324A Melon pickup and loading machine 失效
标题翻译：甜瓜拾取和装载机
公开(公告)号：US3986324A
公开(公告)日：1976-10-19
申请号：US539915
申请日：1975-01-09
申请人： Billie Lee Harriott , Rodney B. Williams , Jerry A. Taylor
发明人： Billie Lee Harriott , Rodney B. Williams , Jerry A. Taylor
IPC分类号： A01D45/00 , A01D51/00
CPC分类号： A01D45/00 , A01D51/00
摘要： A machine for guiding melons from the ground onto lifting and distributing conveyors, having a fence for guiding melons along the ground toward a lift wheel which is rotating about a substantially horizontal axis, the wheel having flexible fingers extending radially therefrom to sweep the melons toward an upwardly inclined conveyor belt.
摘要翻译：一种用于将瓜子从地面引导到提升和分配输送机上的机器，其具有用于沿着地面引导瓜子的围栏朝着基本上水平的轴线旋转的提升轮，该轮具有从其径向延伸的柔性指状物以朝向向上倾斜的输送带。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式