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1. 发明申请

US20050266520A1 Process for the synthesis of peptides 失效
标题翻译：合成肽的方法
公开(公告)号：US20050266520A1
公开(公告)日：2005-12-01
申请号：US10513285
申请日：2003-05-02
申请人： David Evans , Dean Simpkin , Donald Wellings , Eric Atherton
发明人： David Evans , Dean Simpkin , Donald Wellings , Eric Atherton
IPC分类号： C07C271/20 , C07C279/14 , C07C323/60 , C07D209/20 , C07D233/54 , C07K1/00 , C07K7/06 , C07K14/75 , C12P21/06
CPC分类号： C07D233/64 , C07C271/20 , C07C279/14 , C07C323/60 , C07C2603/18 , C07D209/20 , C07K1/003 , C07K7/06 , C07K14/75 , Y02P20/55
摘要： A process is provided for the solid-phase synthesis of a peptide amide which comprises attaching a α-nitrogen protect Cα-carboxamide amino acid to a solid support by its side chain, removing the α-nitrogen protecting group, assembling a peptide chain on said α-nitrogen and then cleaving the assembled peptide amide from the solid support. Novel amino acid analogues, peptide amides and solid-phase supports are also provided.
摘要翻译：提供了一种用于肽酰胺的固相合成的方法，其包括通过其侧链将α-氮保护的卡波酰胺氨基酸连接到固体支持物上，除去α-氮保护基团，在所述然后从固体支持物切割组装的肽酰胺。还提供了新的氨基酸类似物，肽酰胺和固相载体。

2. 发明申请

US20170276824A1 IMAGE QUALITY TEST ARTICLE SET 审中-公开
公开(公告)号：US20170276824A1
公开(公告)日：2017-09-28
申请号：US15514247
申请日：2015-09-25
申请人： Eric ATHERTON , Matthew ADERHOLDT , Joseph REGENSBUGER , Lucinda FLAHERTY , Joseph COCHRAN , Battelle Memorial Institute
发明人： Eric Atherton , Matthew Aderholdt , Joseph Regensburger , Lucinda Flaherty , Joseph Cochran
IPC分类号： G01V5/00 , G01V13/00
CPC分类号： G01V5/005 , G01V5/0008 , G01V13/00
摘要： Systems, methods, and apparatuses are provided for evaluating an image quality of an image produced by an x-ray computed tomography (CT) system.

3. 发明申请

US20110094734A1 DOWNHOLE TOOL 失效
标题翻译：卧式工具
公开(公告)号：US20110094734A1
公开(公告)日：2011-04-28
申请号：US12990356
申请日：2009-05-01
申请人： Eric Atherton , Tim Jones
发明人： Eric Atherton , Tim Jones
IPC分类号： E21B47/09 , E21B43/00
CPC分类号： E21B43/11 , E21B43/119 , E21B47/08 , E21B47/09 , E21B49/00 , G01B5/18
摘要： A means of investigating the quality and/or nature of perforations in a downhole environment is disclosed. A ‘pecking’ finger and depth measuring probe that can be axially and radially displaced enables the perforation to be located and its depth determined, through sequentially pecking around the wall lining in patterns such as radial, axial, and spiral sequences. By swinging a pecking finger that supports a depth measuring probe or cable with a bullet or conically shaped tip and measuring the displacement of the finger, the edge and centre of the hole can be determined with the largest displacement being when the tip is fully in the hole. When this position has been determined, the depth measuring cable is deployed and the depth of the perforation can be established by both an increase in the force required to push the cable and by the displacement of the pecking finger as it is pushed back by the reaction forces on the cable. Thus, a downhole tool comprises a elongate housing for insertion into a downhole environment, from which a probe extends radially by a variable amount, means for driving the probe in a radial direction, and means for sensing resistance to outward radial movement of the probe. One or more radially extendable clamps can be provided for fixing the tool within a surrounding bore. These can be at the upper and/or lower ends of the tool. Ideally, they are moveable between an extended and a retracted position by interengagement with a member moveable relative to a remainder of the tool in a direction that is longitudinal relative to the tool. The member can be, for example, a sleeve extending longitudinally around the tool, the sleeve being moveable longitudinally along the tool. These clamps could be used to fix other types of tool in place in a downhole environment, or one similar to a downhole environment.
摘要翻译：公开了一种调查井下环境中穿孔质量和/或性质的方法。可以轴向和径向移位的“啄食”手指和深度测量探头能够穿孔，并通过依次以径向，轴向和螺旋序列的图案啄围墙壁衬垫来确定其深度。通过摆动支撑深度测量探头或电缆的啄食手指，其具有子弹或锥形尖端并测量手指的位移，可以确定孔的边缘和中心，其中最大的位移是当尖端完全在孔。当确定了该位置时，部署深度测量电缆，并且可以通过增加推动电缆所需的力和通过反作用力推动啄食指的位移来建立穿孔的深度力量在电缆上。因此，井下工具包括用于插入到井下环境中的细长壳体，探针从其径向径向延伸可变量，用于沿径向驱动探针的装置，以及用于感测抵抗探针向外径向运动的阻力的装置。可以提供一个或多个可径向延伸的夹具用于将工具固定在周围的孔内。这些可以在工具的上端和/或下端。理想地，它们可以通过与相对于工具的纵向方向相对于工具的其余部分可移动的构件相互接合而在伸展和缩回位置之间移动。构件可以是例如围绕工具纵向延伸的套筒，套筒可以沿着工具纵向移动。这些夹具可用于将其他类型的工具固定在井下环境中，或者类似于井下环境中。

4. 发明申请

US20100247335A1 System for Monitoring an Electrical Submersible Pump 有权
标题翻译：电潜泵监控系统
公开(公告)号：US20100247335A1
公开(公告)日：2010-09-30
申请号：US12664691
申请日：2008-06-09
申请人： Eric Atherton
发明人： Eric Atherton
IPC分类号： F04B49/06 , F04B35/04 , G01C19/56
CPC分类号： F04D15/00 , E21B43/128 , E21B47/0007 , F04D13/08 , F04D13/10 , F04D15/0088 , F04D15/0094 , H02K5/132 , H02K11/21
摘要： A system for monitoring an Electrical Submersible Pump is disclosed comprising a rotation rate sensor located in an ESP gauge (6). When the Electrical Submersible Pump is started the rotating elements rotate in a first direction whilst the static elements will experience an opposing torque in a second opposite direction. The small rotational movement of the ESP gauge housing is sensed by the sensor and is used to determine the initial direction of rotation of the motor (5) and pump (6).
摘要翻译：公开了一种用于监测电潜泵的系统，其包括位于ESP量规（6）中的旋转速率传感器。当电潜泵启动时，旋转元件沿第一方向旋转，而静态元件将在相反的第二方向上经历相反的扭矩。传感器检测到ESP表壳的小旋转运动，用于确定电机（5）和泵（6）的初始旋转方向。

5. 发明授权

US08752622B2 Downhole tool for investigating perforations 失效
标题翻译：用于调查穿孔的井下工具
公开(公告)号：US08752622B2
公开(公告)日：2014-06-17
申请号：US12990356
申请日：2009-05-01
申请人： Eric Atherton , Tim Jones
发明人： Eric Atherton , Tim Jones
IPC分类号： E21B47/09
CPC分类号： E21B43/11 , E21B43/119 , E21B47/08 , E21B47/09 , E21B49/00 , G01B5/18
摘要： To investigate the quality and nature of perforations in a downhole environment, a ‘pecking’ finger and depth measuring probe that can be axially and radially displaced enables the perforation to be located and its depth determined, through sequentially pecking around the wall lining. By swinging a pecking finger supporting a depth measuring probe tip and measuring the displacement of the finger, the edge and center of the hole can be determined with the largest displacement being when the tip is fully in the hole. The depth measuring probe is then deployed and the depth of the perforation established by an increase in the force required to push the probe and by the displacement of the pecking finger as it is pushed back by the reaction forces. Radially extendable clamps at the ends of the tool fix the tool with a surrounding bore.
摘要翻译：为了研究井下环境中穿孔的质量和性质，可以轴向和径向位移的“啄食”手指和深度测量探头可以通过依次啄围墙壁衬套来确定穿孔并确定其深度。通过摆动支撑深度测量探针尖端的啄食手指并测量手指的位移，可以确定孔的边缘和中心，其中最大的位移是当尖端完全在孔中时。然后深度测量探头被展开，并且通过增加推动探针所需的力以及在被反作用力推回时啄食指的移动而建立穿孔的深度。工具端部的可径向延伸的夹具用周围的孔固定工具。

6. 发明授权

US08111170B2 Remote area sensor system 有权
标题翻译：远程区域传感器系统
公开(公告)号：US08111170B2
公开(公告)日：2012-02-07
申请号：US12162450
申请日：2007-01-26
申请人： James Nicholas Wilson , Eric Atherton
发明人： James Nicholas Wilson , Eric Atherton
IPC分类号： G08B1/08
CPC分类号： H04Q9/00 , E21B47/12 , G08C17/02 , H04Q2209/25 , H04Q2209/40 , H04Q2209/886
摘要： A communications system comprises a primary wireless network and at least one secondary wireless networks, the primary and secondary wireless networks differing in at least one characteristic, at least one sensor unit comprising a means for sensing a parameter and a node of that secondary network adapted to transmit data relating to the parameter via that secondary network, at least one local data gathering point associated with the at least one secondary wireless network, incorporating a node of that secondary wireless network, a node of the primary network, and a control unit adapted to receive data signals from the at least one sensor unit via the secondary network, construct an outgoing data signal incorporating information from the received data signal, and transmit the outgoing data signal via the primary network, the primary wireless network being a multipoint radio network. The primary wireless network is optimized for relatively long distance communications, of the order of 10 kin, and the secondary network or networks are optimized for relatively short distance communications of the order of 100 m, the radio power of each network being different and appropriate for each transmission distance required. The nodes of the primary network may contain GPS receivers, to synchronize the sensors with which the nodes communicate, and aid routing performance of the primary wireless meshing network.
摘要翻译：通信系统包括主无线网络和至少一个辅助无线网络，主要和次要无线网络在至少一个特征中不同，至少一个传感器单元包括用于感测参数的装置和适于经由该次要网络发送与该参数相关的数据，与至少一个辅助无线网络相关联的至少一个本地数据收集点，其包含该次要无线网络的节点，该主要网络的节点以及适于通过次要网络接收来自至少一个传感器单元的数据信号，构建从接收到的数据信号中合并信息的输出数据信号，并通过主网络传输输出数据信号，主无线网络是多点无线电网络。主要无线网络针对相对长距离通信进行了优化，数量级为10个，并且辅助网络或网络针对100米级的相对较短的距离通信进行了优化，每个网络的无线电功率不同，适用于每个传输距离需要。主网络的节点可以包含GPS接收器，以使与节点通信的传感器同步，并且辅助主无线网状网络的路由性能。

7. 发明申请

US20090027227A1 Remote area Sensor System 有权
标题翻译：远程区域传感器系统
公开(公告)号：US20090027227A1
公开(公告)日：2009-01-29
申请号：US12162450
申请日：2007-01-26
申请人： James Nicholas Wilson , Eric Atherton
发明人： James Nicholas Wilson , Eric Atherton
IPC分类号： H04Q9/00
CPC分类号： H04Q9/00 , E21B47/12 , G08C17/02 , H04Q2209/25 , H04Q2209/40 , H04Q2209/886
摘要： A communications system comprises a primary wireless network and at least one secondary wireless networks, the primary and secondary wireless networks differing in at least one characteristic, at least one sensor unit comprising a means for sensing a parameter and a node of that secondary network adapted to transmit data relating to the parameter via that secondary network, at least one local data gathering point associated with the at least one secondary wireless network, incorporating a node of that secondary wireless network, a node of the primary network, and a control unit adapted to receive data signals from the at least one sensor unit via the secondary network, construct an outgoing data signal incorporating information from the received data signal, and transmit the outgoing data signal via the primary network, the primary wireless network being a multipoint radio network. The primary wireless network is optimised for relatively long distance communications, of the order of 10 km, and the secondary network or networks are optimised for relatively short distance communications of the order of 100 m, the radio power of each network being different and appropriate for each transmission distance required. This means that the secondary wireless network can have a restricted power output suitable for use proximate to wellheads, with the result that the range is unlikely to be greater than 1 km. The at least one sensor can be an oil or gas wellhead pressure sensor, preferably self powered. The nodes of the primary network may contain GPS receivers, to synchronise the sensors with which the nodes communicate, and aid routing performance of the primary wireless meshing network.
摘要翻译：通信系统包括主无线网络和至少一个辅助无线网络，主要和次要无线网络在至少一个特征中不同，至少一个传感器单元包括用于感测参数的装置和适于经由该次要网络发送与该参数相关的数据，与至少一个辅助无线网络相关联的至少一个本地数据收集点，其包含该次要无线网络的节点，该主要网络的节点以及适于通过次要网络接收来自至少一个传感器单元的数据信号，构成从接收到的数据信号中包含信息的输出数据信号，并通过主网络传输输出数据信号，主无线网络是多点无线电网络。主要无线网络针对距离较远的通信进行了优化，距离通信距离为10公里，对于距离较远的通信距离为100米的二级网络进行了优化，每个网络的无线电功率不同，适用于每个传输距离需要。这意味着辅助无线网络可以具有适合在井口附近使用的受限制的功率输出，结果是该范围不大于1km。所述至少一个传感器可以是油或气体井口压力传感器，优选为自供电的。主网络的节点可以包含GPS接收器，以使与节点通信的传感器同步，并且辅助主无线网状网络的路由性能。

8. 发明申请

US20170269256A1 IMAGE QUALITY TEST ARTICLE 审中-公开
公开(公告)号：US20170269256A1
公开(公告)日：2017-09-21
申请号：US15514232
申请日：2015-09-25
申请人： Eric ATHERTON , Matthew ADERHOLDT , Joseph REGENSBUGER , Lucinda FLAHERTY , Joseph COCHRAN , Battelle Memorial Institute
发明人： Eric Atherton , Matthew Aderholdt , Joseph Regensburger , Lucinda Flaherty , Joseph Cochran
IPC分类号： G01V5/00 , G01T1/02
摘要： Apparatuses are provided for evaluating an image quality of an image produced by an x-ray computed tomography (CT) system.

9. 发明申请

US20080272904A1 Signalling Method 审中-公开
标题翻译：信令方式
公开(公告)号：US20080272904A1
公开(公告)日：2008-11-06
申请号：US11570941
申请日：2005-06-24
申请人： Eric Atherton
发明人： Eric Atherton
IPC分类号： G08B1/08
CPC分类号： H04L1/246 , E21B47/12 , G01V11/00 , H03K7/08 , H03K9/08 , H04B3/54 , H04B2203/5475 , H04L25/4902
摘要： An electrical signalling system comprises a modulator arranged to accept information and encode that information in an alternating signal containing repeated rising and falling edges, the encoding being by way of the time between consecutive rising and falling edges a transmission path for the signal from the modulator to a demodulator, wherein the modulator is arranged to precede a data signal with a reference signal of a known time, and the demodulator is arranged to detect that reference signal and calculate a calibration error therefrom. The demodulator can record the calibration error and subtract this from subsequent data signals. The demodulator can alternatively (or in addition) adjust the threshold for future signals, on the basis of the calibration error. This is particularly suited to inductive transmission paths such as a three-phase electrical supply cable leading to downhole sensors in the oil and gas extraction industries.
摘要翻译：一种电信令系统，包括调制器，被配置为接收信息并将信息编码在包含重复的上升沿和下降沿的交替信号中，该编码通过连续上升沿和下降沿之间的时间，来自调制器的信号的传输路径解调器，其中所述调制器被布置为在数据信号之前具有已知时间的参考信号，并且所述解调器被布置为检测所述参考信号并从其计算校准误差。解调器可以记录校准误差，并将其从后续数据信号中减去。另外（或另外）解调器可以根据校准误差来调整未来信号的阈值。这特别适用于感应传输路径，例如通往油气开采行业的井下传感器的三相供电电缆。

10. 发明授权

US07299678B2 Sensor apparatus 有权
标题翻译：传感器装置
公开(公告)号：US07299678B2
公开(公告)日：2007-11-27
申请号：US10240134
申请日：2001-03-27
申请人： Eric Atherton
发明人： Eric Atherton
IPC分类号： G01N27/00
CPC分类号： E21B47/06 , E21B47/065 , E21B47/12 , G01L9/0022 , Y10S73/01
摘要： A measurement head particularly for borehole use can measure multiple parameters with no electronics in the head and only a single conductor cable. Double-ended tuning forks (26, 28 and 38, 40) in the head are arranged to respond to different parameters such as temperature and pressure by adjusting their resonant frequencies. A drive signal on the conductor (50) is applied to transducers (30, 32, 42, 44) on all the tuning forks and those whose instantaneous resonant frequency is close will resonate. The signal is removed and the transducers return a decaying signal at the resonant frequency along the conductor. Other drive frequencies are tried, to locate the other sensors whose frequency ranges are separate.
摘要翻译：特别用于钻孔使用的测量头可以测量多个参数，头部中没有电子元件，只能使用单根导体电缆。头部中的双端调谐叉（26,28和38,40）被布置成通过调节其谐振频率来响应诸如温度和压力的不同参数。导体（50）上的驱动信号被施加到所有调谐叉上的换能器（30,32,44,44），并且其瞬时谐振频率接近的谐振频率将共振。信号被去除，换能器沿着导体以谐振频率返回衰减信号。尝试其他驱动频率，以定位频率范围分开的其他传感器。

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