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1. 发明授权

US08934098B2 Fast-indexing filter wheel and method of use 有权
标题翻译：快速分度过滤轮及使用方法
公开(公告)号：US08934098B2
公开(公告)日：2015-01-13
申请号：US12873132
申请日：2010-08-31
申请人： David Cox , Marc Haberstroh , Patrick Kinney , Albert Carrillo , Jon Hoshizaki , Maryam Shariati , Howard King , Joe Lee , Matthew Chan
发明人： David Cox , Marc Haberstroh , Patrick Kinney , Albert Carrillo , Jon Hoshizaki , Maryam Shariati , Howard King , Joe Lee , Matthew Chan
IPC分类号： G01N21/25 , C12Q1/68 , B01F13/00 , B01F13/02 , B01J19/00 , B01L3/00 , G01N35/00 , G01N35/10 , G02B21/34
CPC分类号： C12Q1/6869 , B01F13/0059 , B01F13/0222 , B01J19/0046 , B01J2219/00317 , B01J2219/00466 , B01J2219/00527 , B01J2219/00576 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00722 , B01L3/502707 , B01L3/50273 , B01L2200/027 , B01L2200/0647 , B01L2200/0684 , B01L2200/16 , B01L2300/0819 , B01L2300/0822 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2300/1822 , B01L2400/0427 , C12Q1/6874 , G01N35/00069 , G01N35/1002 , G01N35/1097 , G01N2035/00148 , G01N2035/00237 , G01N2035/1034 , G02B21/34 , Y10T436/11 , Y10T436/143333
摘要： Various embodiments of a sequencing system capable of rapidly imaging samples at multiple wavelengths are provided herein. In one embodiment, the system includes a fast-indexing filter wheel having a plurality of excitation and emission filters capable of being rapidly rotated into and out of communication with an excitation source (e.g., an arc lamp, a laser. For example, the filter wheel can be configured to index in an amount of time falling within a range of about 40 ms to about 60 ms, preferably 50 ms. The system can also be configured to account for vibrations resulting from the quick starts and stops of the fast-indexing filter wheel as well as vibrations resulting from other sources. Various methods of rapidly imaging a sample at multiple wavelengths are also provided herein.
摘要翻译：本文提供了能够快速成像多个波长的样品的测序系统的各种实施例。在一个实施例中，该系统包括具有多个激发和发射滤波器的快速分度滤光轮，该激发和发射滤光片能够快速旋转进入激发源（例如，弧光灯，激光器）轮可以被配置成以大约40ms至大约60ms，优选为50ms的范围内的时间量进行索引。该系统还可以被配置为考虑快速启动和停止快速索引所产生的振动滤光轮以及由其他光源产生的振动。本文还提供了在多个波长下快速成像样品的各种方法。

2. 发明申请

US20110128545A1 Fast-Indexing Filter Wheel and Method of Use 有权
标题翻译：快速分度滤芯轮和使用方法
公开(公告)号：US20110128545A1
公开(公告)日：2011-06-02
申请号：US12873132
申请日：2010-08-31
申请人： David Cox , Marc Haberstroh , Patrick Kinney , Albert Carrillo , Jon Hoshizaki , Maryam Shariati , Howard King , Joe Lee , Matthew Chan
发明人： David Cox , Marc Haberstroh , Patrick Kinney , Albert Carrillo , Jon Hoshizaki , Maryam Shariati , Howard King , Joe Lee , Matthew Chan
IPC分类号： G01N21/25 , G02B5/22
CPC分类号： C12Q1/6869 , B01F13/0059 , B01F13/0222 , B01J19/0046 , B01J2219/00317 , B01J2219/00466 , B01J2219/00527 , B01J2219/00576 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00722 , B01L3/502707 , B01L3/50273 , B01L2200/027 , B01L2200/0647 , B01L2200/0684 , B01L2200/16 , B01L2300/0819 , B01L2300/0822 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2300/1822 , B01L2400/0427 , C12Q1/6874 , G01N35/00069 , G01N35/1002 , G01N35/1097 , G01N2035/00148 , G01N2035/00237 , G01N2035/1034 , G02B21/34 , Y10T436/11 , Y10T436/143333
摘要： Various embodiments of a sequencing system capable of rapidly imaging samples at multiple wavelengths are provided herein. In one embodiment, the system includes a fast-indexing filter wheel having a plurality of excitation and emission filters capable of being rapidly rotated into and out of communication with an excitation source (e.g., an arc lamp, a laser. For example, the filter wheel can be configured to index in an amount of time falling within a range of about 40 ms to about 60 ms, preferably 50 ms. The system can also be configured to account for vibrations resulting from the quick starts and stops of the fast-indexing filter wheel as well as vibrations resulting from other sources. Various methods of rapidly imaging a sample at multiple wavelengths are also provided herein.
摘要翻译：本文提供了能够快速成像多个波长的样品的测序系统的各种实施例。在一个实施例中，该系统包括具有多个激发和发射滤波器的快速分度滤光轮，该激发和发射滤光片能够快速旋转进入激发源（例如，弧光灯，激光器）轮可以被配置成以大约40ms至大约60ms，优选为50ms的范围内的时间量进行索引。该系统还可以被配置为考虑快速启动和停止快速索引所产生的振动滤光轮以及由其他光源产生的振动。本文还提供了在多个波长下快速成像样品的各种方法。

3. 发明授权

US11466795B2 Fastener 有权
公开(公告)号：US11466795B2
公开(公告)日：2022-10-11
申请号：US17248790
申请日：2021-02-08
申请人： David Cox
发明人： David Cox
IPC分类号： F16L3/04 , F16B15/00
摘要： A fastener for fastening pipes or electrical conduit can be installed with the optional use of nails or screws. The fastener includes sharp teeth or spikes which can be hammered into an external surface, such as wood or masonry. The teeth or spikes are positioned, oriented, and otherwise configured to best suit the intended application. Installation can be accomplished using only the fastener itself and force exceeding a minimal threshold.

4. 发明授权

US10650280B2 Systems and methods for machine learning enhanced by human measurements 有权
公开(公告)号：US10650280B2
公开(公告)日：2020-05-12
申请号：US16381291
申请日：2019-04-11
申请人： David Cox , Walter Scheirer , Samuel Anthony , Ken Nakayama
发明人： David Cox , Walter Scheirer , Samuel Anthony , Ken Nakayama
IPC分类号： G06K9/00 , G06K9/62
摘要： In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least its part on the human-weighted loss function.

5. 发明授权

US09194772B2 Apparatus, system, and method using immiscible-fluid-discrete-volumes 有权
标题翻译：使用不混溶流体离散体的装置，系统和方法
公开(公告)号：US09194772B2
公开(公告)日：2015-11-24
申请号：US12557488
申请日：2009-09-10
申请人： Linda Lee , Sam Woo , Congcong Ma , Richard Reel , Mark Oldham , David Cox , Benjamin Schroeder , Jon Sorenson , Willy Wiyatno
发明人： Linda Lee , Sam Woo , Congcong Ma , Richard Reel , Mark Oldham , David Cox , Benjamin Schroeder , Jon Sorenson , Willy Wiyatno
IPC分类号： C12Q1/68 , C12M1/34 , G01N1/14 , B01L3/00 , F15C5/00 , F16K99/00 , G01N35/08 , B01L3/02 , B01L7/00
CPC分类号： C12Q1/6869 , B01J2219/00353 , B01J2219/0036 , B01J2219/00364 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00626 , B01J2219/00637 , B01J2219/00653 , B01J2219/00657 , B01J2219/00659 , B01L3/0293 , B01L3/502715 , B01L3/502784 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2300/0864 , B01L2300/0867 , B01L2400/0421 , B01L2400/0487 , C12Q1/6806 , C12Q1/6874 , F15C5/00 , F16K99/0001 , F16K99/0011 , F16K99/0013 , F16K2099/0084 , G01N1/14 , G01N27/44743 , G01N27/44769 , G01N35/08 , Y10T137/0318 , Y10T137/4259 , Y10T137/85978 , Y10T137/85986 , Y10T137/86863 , Y10T436/2575 , C12Q2535/101
摘要： Various embodiments of the teachings relate to a system or method for sample preparation or analysis in biochemical or molecular biology procedures. The sample preparation can involve small volume processed in discrete portions or segments or slugs, herein referred to as discrete volumes. A molecular biology procedure can be nucleic acid analysis. Nucleic acid analysis can be an integrated DNA amplification/DNA sequencing procedure.
摘要翻译：本发明的各种实施方案涉及生物化学或分子生物学程序中用于样品制备或分析的系统或方法。样品制备可以涉及在离散部分或段或块中的小体积处理，在本文中称为离散体积。分子生物学程序可以是核酸分析。核酸分析可以是一个综合的DNA扩增/ DNA测序程序。

6. 发明授权

US08719906B2 Reactive authorization for publications 有权
标题翻译：出版物的无效授权
公开(公告)号：US08719906B2
公开(公告)日：2014-05-06
申请号：US13321593
申请日：2009-05-28
申请人： Christer Boberg , David Cox , Mikael Klein , Sofie Lassborn , Anders Lindgren
发明人： Christer Boberg , David Cox , Mikael Klein , Sofie Lassborn , Anders Lindgren
IPC分类号： H04L29/06 , G06F21/62
CPC分类号： G06F21/6245 , G06F21/6272 , H04L63/102 , H04L67/24
摘要： Systems and methods for reactively authorizing publication of information by a third party are coordinated through the use of a presence server. The presence server communicates with other communication nodes/devices to determine and relay publication information. Publication requests that are initially unauthorized, from the perspective of the presence server, are resolved.
摘要翻译：通过使用存在服务器来协调由第三方反复授权信息发布的系统和方法。存在服务器与其他通信节点/设备通信以确定和中继发布信息。从出现服务器的角度来看，最初未经授权的发布请求已被解决。

7. 发明申请

US20130207791A1 HAPTIC DIRECTIONAL FEEDBACK HANDLES FOR LOCATION DEVICES 有权
标题翻译：用于位置设备的HAPTIC DIRECTIONAL FEEDBACK HANDLES
公开(公告)号：US20130207791A1
公开(公告)日：2013-08-15
申请号：US13570084
申请日：2012-08-08
申请人： Mark S. Olsson , Garrett A. Newby , Alexander Logan Warren , David Cox
发明人： Mark S. Olsson , Garrett A. Newby , Alexander Logan Warren , David Cox
IPC分类号： G08B6/00
CPC分类号： G08B6/00 , G01V3/081 , G01V3/12 , G01V3/165
摘要： Locating devices and systems providing haptic tactile feedback are disclosed. In one embodiment, a locator includes a haptic handle configured to provide directional signals through an operator's sense of touch to aid in locating and tracing a buried conductor or other object such as a pipe or cable.
摘要翻译：公开了提供触觉触觉反馈的定位装置和系统。在一个实施例中，定位器包括触觉手柄，其被配置为通过操作者的触感来提供定向信号，以帮助定位和跟踪掩埋的导体或其它物体，例如管道或电缆。

8. 发明授权

US08499726B2 Internal combustion engines 有权
标题翻译：内燃机
公开(公告)号：US08499726B2
公开(公告)日：2013-08-06
申请号：US12663519
申请日：2008-05-28
申请人： David Cox
发明人： David Cox
IPC分类号： F01B7/12 , F02B25/08 , F02B75/28
CPC分类号： F01B9/023 , F01B1/08 , F01B7/04 , F01B7/10 , F02B25/08 , F02B75/24 , F02B75/28 , F02B2075/025 , F02B2075/1808 , F02B2275/40 , F02F1/22 , F02F3/0015 , Y02T10/125
摘要： The invention provides a 2-stroke internal combustion engine comprising two opposed cylinders, each cylinder housing two opposed pistons and having at least one exhaust port and at least one intake port, and a crankshaft having asymmetrically arranged journals and scotch-yoke mechanisms for driving the journals from the pistons. The pistons in each cylinder operate to open its exhaust port or ports before its intake port or ports and to close its exhaust port or ports before its intake port or ports.
摘要翻译：本发明提供一种二冲程内燃机，其包括两个相对的气缸，每个气缸容纳两个相对的活塞并且具有至少一个排气口和至少一个进气口，以及具有不对称排列的轴颈和用于驱动来自活塞的期刊。每个气缸中的活塞在其进气口或端口之前操作以打开其排气端口，并在其进气口或端口之前关闭其排气口或端口。

9. 发明申请

US20120304252A1 METHOD AND SYSTEM FOR AUTHORIZATION OF PRESENCE INFORMATION 有权
标题翻译：用于授权存在信息的方法和系统
公开(公告)号：US20120304252A1
公开(公告)日：2012-11-29
申请号：US13574696
申请日：2010-01-27
申请人： Christer Boberg , Mikael Klein , Anders Lindgren , Sofie Lassborn , David Cox
发明人： Christer Boberg , Mikael Klein , Anders Lindgren , Sofie Lassborn , David Cox
IPC分类号： G06F21/00
CPC分类号： H04L67/24 , H04L63/105
摘要： Embodiments of the present invention include a system and method for implementing a presence system. According to an embodiment of the present invention, responsive to receiving a request for presence information associated with a presentity from a watcher, the presence system receives instructions indicating that an authorization instance other than the presentity shall be given an opportunity to change or verify an authorization rule associated with the request for presence information. As a consequence, the presence system notifies the authorization instance of the request for presence information, thereby enabling the authorization instance to change or verify the authorization rule. The presence system also makes a final decision on the authorization rule on the basis of the instructions and a notification indicating a change or verification of the authorization rule.
摘要翻译：本发明的实施例包括用于实现存在系统的系统和方法。根据本发明的实施例，响应于从观察者接收到与呈现体相关联的存在信息的请求，存在系统接收指示，指示除了呈现体之外的授权实例有机会改变或验证授权与存在信息请求相关联的规则。因此，存在系统通知授权实例对存在信息的请求，从而使授权实例能够改变或验证授权规则。存在系统还根据指令和指示更改或验证授权规则的通知对授权规则作出最终决定。

10. 发明申请

US20100114110A1 INTERVERTEBRAL DISC ACCESS ASSEMBLY 审中-公开
公开(公告)号：US20100114110A1
公开(公告)日：2010-05-06
申请号：US12261142
申请日：2008-10-30
申请人： Richard J. Taft , Robert Nucci , George Morrison , David Cox
发明人： Richard J. Taft , Robert Nucci , George Morrison , David Cox
IPC分类号： A61F11/00 , A61B18/14 , A61M5/24
CPC分类号： A61B17/025 , A61B17/3421 , A61B17/3494 , A61B18/1482 , A61B90/11 , A61B90/39 , A61B2017/00261 , A61B2017/0256 , A61B2017/347 , A61B2090/034 , A61B2090/376
摘要： A surgical access system for managing the minimally invasive access of treatment electrodes to an intervertebral disc, when treating spine abnormalities such as disc herniations. The system includes an access port and a cannula assembly. The access port provides atraumatic access to the target area for the cannula system and a subsequent treatment electrode. The access port also manages the insertion travel and penetration depth of the cannula assembly, so as to minimize unintended damage to local tissue during use. The cannula system includes an adjustable and removable stop to mate with the access port that limits the extension of the cannula beyond the distal tip of the access port and into the target tissue.
摘要翻译：一种手术进入系统，用于在治疗椎间盘异常（如椎间盘突出）时，将治疗电极的微创入路管理到椎间盘。该系统包括进入口和插管组件。进入端口提供对插管系统的目标区域的无创访问和随后的治疗电极。进出口还管理插管组件的插入行程和穿透深度，以便在使用期间最小化对局部组织的意外伤害。插管系统包括可调节和可移除的止动件，以与入口端口配合，限制套管延伸超出进入端口的远端并进入目标组织。

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