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1. 发明授权

US10271941B2 Implant and method for producing the same 有权
公开(公告)号：US10271941B2
公开(公告)日：2019-04-30
申请号：US13090479
申请日：2011-04-20
申请人： Daniel Wintsch , Stefan Loher , Bodo Quint , Patrice Bachmann , Hans Lang , Dragica Pantic , Alwin Schwitzer
发明人： Daniel Wintsch , Stefan Loher , Bodo Quint , Patrice Bachmann , Hans Lang , Dragica Pantic , Alwin Schwitzer
IPC分类号： A61F2/08 , A61F2/07 , A61L31/06 , A61F2/90
摘要： An implant having a preferably hollow cylindrical basic structure. A nonwoven fabric is disposed in and/or on the basic structure, the nonwoven fabric preferably comprising biocompatible thermoplastic polyurethane and/or a polymer selected from the group consisting of polylactic acid; polycaprolactone, and a copolymer thereof, and/or a polymer including polyphosphazene. At least in at least one section of the implant, preferably at the proximal and/or distal ends of the implant, fastening means are provided or the nonwoven fabric is treated such that, at least in the expanded state of the implant, the protrusion of nonwoven fabric sections from the implant is significantly reduced. Furthermore, a method for producing such an implant is provided.

2. 发明申请

US20110262684A1 IMPLANT AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：植入物及其制造方法
公开(公告)号：US20110262684A1
公开(公告)日：2011-10-27
申请号：US13090479
申请日：2011-04-20
申请人： Daniel Wintsch , Stefan Loher , Bodo Quint , Patrice Bachmann , Hans Lang , Dragica Pantic , Alwin Schwitzer
发明人： Daniel Wintsch , Stefan Loher , Bodo Quint , Patrice Bachmann , Hans Lang , Dragica Pantic , Alwin Schwitzer
IPC分类号： B32B3/06 , B32B7/08
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/072 , A61F2250/0063 , A61L31/06 , Y10T428/24008 , C08L75/04
摘要： An implant having a preferably hollow cylindrical basic structure. A nonwoven fabric is disposed in and/or on the basic structure, the nonwoven fabric preferably comprising biocompatible thermoplastic polyurethane and/or a polymer selected from the group consisting of polylactic acid; polycaprolactone, and a copolymer thereof, and/or a polymer including polyphosphazene. At least in at least one section of the implant, preferably at the proximal and/or distal ends of the implant, fastening means are provided or the nonwoven fabric is treated such that, at least in the expanded state of the implant, the protrusion of nonwoven fabric sections from the implant is significantly reduced. Furthermore, a method for producing such an implant is provided.
摘要翻译：具有优选中空圆柱形基本结构的植入物。非织造布设置在基本结构中和/或基本结构上，无纺布优选包含生物相容性热塑性聚氨酯和/或选自聚乳酸的聚合物; 聚己内酯及其共聚物，和/或包含聚磷腈的聚合物。至少在植入物的至少一个部分中，优选地在植入物的近端和/或远端处，提供紧固装置，或者非织造织物被处理，使得至少在植入物的展开状态下，来自植入物的非织造织物部分显着减少。此外，提供了一种用于制造这种植入物的方法。

3. 发明申请

US20080233356A1 Method for the Application of a Structured Coating Upon a Smooth Surface 审中-公开
标题翻译：结构化涂层在光滑表面上的应用方法
公开(公告)号：US20080233356A1
公开(公告)日：2008-09-25
申请号：US12066589
申请日：2005-09-12
申请人： Stefan Loher , Wendelin J. Stark
发明人： Stefan Loher , Wendelin J. Stark
IPC分类号： B05D5/08 , B05D3/00 , B32B3/00 , C08L83/04
CPC分类号： B05D1/28 , C09D183/04 , Y10T428/24612
摘要： A roll coating method for preparing a coated substrate with structured surface of the coating is described. Said method comprises application of a polymer based coating fluid to a substrate surface by means of a coating fluid application roll and then curing the applied coating, wherein the polymer based coating fluid is a fluid showing Bingham or Herschel-Bulkley flow behavior with a yield stress τ0>10 dyn cm−2, in particular a fluid having low viscosity at high shear rate, fast viscosity enhancement in the absence of shear stress and a high yield stress. Applications of such produced surfaces are release films, e.g. for pressure sensitive adhesives, controlled release adhesives and self-cleaning surfaces and friction coefficient reducing surfaces.
摘要翻译：描述了一种用于制备具有涂层结构化表面的涂覆基材的辊涂方法。所述方法包括通过涂布液施加辊将基于聚合物的涂布流体施加到基底表面，然后固化涂覆的涂层，其中基于聚合物的涂布液是显示宾汉姆或赫歇尔 - 普利利流体行为的流体，具有屈服应力特别是在高剪切速率下具有低粘度的液体，在没有剪切应力的情况下快速粘度增强和高屈服应力。这种产生的表面的应用是剥离膜，例如用于压敏粘合剂，控释胶粘剂和自清洁表面和摩擦系数降低表面。

4. 发明申请

US20070196259A1 Flame synthesis of metal salt nanoparticles, in particular calcium and phosphate comprising nanoparticles 有权
标题翻译：金属盐纳米颗粒的火焰合成，特别是包含纳米颗粒的钙和磷酸盐
公开(公告)号：US20070196259A1
公开(公告)日：2007-08-23
申请号：US10592913
申请日：2004-03-15
申请人： Wendelin Stark , Sotiris-Emmanuel Pratsinis , Marek Maciejewski , Stefan Loher , Alfons Baiker
发明人： Wendelin Stark , Sotiris-Emmanuel Pratsinis , Marek Maciejewski , Stefan Loher , Alfons Baiker
IPC分类号： C01F17/00
CPC分类号： C01B25/455 , A61L27/12 , B82Y30/00 , C01B13/34 , C01B17/96 , C01B25/32 , C01F11/18 , C01F11/46 , C01G1/00 , C01G1/02 , C01P2002/54 , C01P2002/72 , C01P2002/82 , C01P2002/88 , C01P2004/03 , C01P2004/04 , C01P2004/64 , C01P2006/12 , C01P2006/13
摘要： Described is a method for the production of metal salts, wherein the cationic metal is preferably selected from Group I to IV metals and mixtures thereof and the anionic group is selected from phosphates, silicates, sulfates, carbonates, hydroxides, fluorides and mixtures thereof, and wherein said method comprises forming a mixture of at least one metal source that is a metal carboxylate with a mean carbon value per carboxylate group of at least 3 and at least one anion source into droplets and oxiding said droplets in a high temperature environment, preferably a flame. This method is especially suited for the production of calcium phosphate biomaterials such as hydroxyapatite (HAp,Cal0(P04)6(OH)2) and tricalcium phosphate (TCP,Ca3(P04)2) that exhibit excellent biocompatibility and osteoconductivity and therefore are widely used for reparation of bony or periodontal defects, coating of metallic implants and bone space fillers.
摘要翻译：描述了一种制备金属盐的方法，其中阳离子金属优选选自I至IV族金属及其混合物，阴离子基团选自磷酸盐，硅酸盐，硫酸盐，碳酸盐，氢氧化物，氟化物及其混合物，以及其中所述方法包括形成至少一种金属源的金属源的混合物，其中每个羧酸盐基团的平均碳值至少为3，至少一个阴离子源的平均碳值为液滴，并在高温环境中氧化所述液滴，优选为火焰。该方法特别适用于生物相容性和骨传导性优良的磷酸钙生物材料如羟基磷灰石（HAp，Cal0（P04）6（OH）2）和磷酸三钙（TCP，Ca3（P04）2）用于修复骨或牙周缺损，金属植入物和骨空间填料的涂层。

5. 发明授权

US08282911B2 Implant material 有权
标题翻译：植入材料
公开(公告)号：US08282911B2
公开(公告)日：2012-10-09
申请号：US12446558
申请日：2006-10-23
申请人： Jan W. Stark , Oliver Schneider , Stefan Loher , Tobias Brunner , Marc Simonet , Patrick Schmidlin , Robert N. Grass
发明人： Jan W. Stark , Oliver Schneider , Stefan Loher , Tobias Brunner , Marc Simonet , Patrick Schmidlin , Robert N. Grass
IPC分类号： A61K8/00
CPC分类号： A61L27/46 , A61K9/0024 , A61K9/70 , A61L2400/12
摘要： The present relates to the field of dental and bone surgery. In particular, the invention relates to fibrous pharmaceutical compositions; fibrous webs, yarns and woven fabrics of such pharmaceutical compositions; to implant material essentially consisting of fibrous pharmaceutical compositions; to the manufacturing and use of such fibers/webs/implant materials.
摘要翻译：本发明涉及牙科和骨科手术领域。特别地，本发明涉及纤维状药物组合物; 这种药物组合物的纤维网，纱线和织造织物; 植入基本上由纤维状药物组合物组成的材料; 涉及这种纤维/网/植入材料的制造和使用。

6. 发明申请

US20100196440A1 Implant Material 有权
标题翻译：植入材料
公开(公告)号：US20100196440A1
公开(公告)日：2010-08-05
申请号：US12446558
申请日：2006-10-23
申请人： Wendelin Jan Stark , Oliver Schneider , Stefan Loher , Tobias Brunner , Marc Simonet , Patrick Schmidlin , Robert N. Grass
发明人： Wendelin Jan Stark , Oliver Schneider , Stefan Loher , Tobias Brunner , Marc Simonet , Patrick Schmidlin , Robert N. Grass
IPC分类号： A61F2/28 , A61K38/16 , A61P43/00 , D01F1/10
CPC分类号： A61L27/46 , A61K9/0024 , A61K9/70 , A61L2400/12
摘要： The present relates to the field of dental and bone surgery. In particular, the invention relates to fibrous pharmaceutical compositions; fibrous webs, yarns and woven fabrics of such pharmaceutical compositions; to implant material essentially consisting of fibrous pharmaceutical compositions; to the manufacturing and use of such fibers/webs/implant materials.
摘要翻译：本发明涉及牙科和骨科手术领域。特别地，本发明涉及纤维状药物组合物; 这种药物组合物的纤维网，纱线和织造织物; 植入基本上由纤维状药物组合物组成的材料; 涉及这种纤维/网/植入材料的制造和使用。

7. 发明申请

US20120321686A1 Antifungal Material 审中-公开
标题翻译：防霉材料
公开(公告)号：US20120321686A1
公开(公告)日：2012-12-20
申请号：US13518569
申请日：2009-12-24
申请人： Stefan Bokorny , Tobias Maienfisch , Stefan Loher , Wendelin J. Stark
发明人： Stefan Bokorny , Tobias Maienfisch , Stefan Loher , Wendelin J. Stark
IPC分类号： A01N59/20 , A01N25/00 , A01N25/04 , A01N25/08 , A01P3/00 , A01N25/10 , B82Y40/00 , B82Y30/00
CPC分类号： A01N59/20 , A01N25/34 , A01N59/16 , C01B25/32 , C01B25/327 , C09D5/14 , C09D7/45 , C09D7/68 , A01N25/04 , A01N25/08 , A01N25/10 , A01N2300/00
摘要： The present invention relates to antifungal materials, particularly to nanoparticles comprising or consisting of a non-persistent inorganic support material such as Tricalciumphosphate (TCP) and copper as a dopant in the form of Cu+/−0, Cu+1 and or Cu+2; to composite materials or liquid formulations containing such nanoparticles. Further, the invention relates to the manufacture of such nanoparticles, composites, liquid formulations and to the use of such nanoparticles, composites, liquid formulations as an antifungal component.
摘要翻译：本发明涉及抗真菌材料，特别涉及纳米颗粒，其包含非永久性无机载体材料如磷酸三钙（TCP）和铜作为Cu +/- 0，Cu + 1和/或Cu + 2形式的掺杂剂 ; 包含这种纳米颗粒的复合材料或液体制剂。此外，本发明涉及这种纳米颗粒，复合材料，液体制剂的制造以及这种纳米颗粒，复合材料，液体制剂作为抗真菌组分的用途。

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