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1. 发明授权

US5407424A Angioplasty perfusion pump 失效
标题翻译：血管成形术灌注泵
公开(公告)号：US5407424A
公开(公告)日：1995-04-18
申请号：US22048
申请日：1993-02-24
申请人： Daniel M. LaFontaine , Thomas J. Holman , Daniel O. Adams
发明人： Daniel M. LaFontaine , Thomas J. Holman , Daniel O. Adams
IPC分类号： A61M1/00 , A61M1/36 , A61M37/00
CPC分类号： A61M1/0005 , A61M1/3613 , A61M1/0062
摘要： A double acting piston blood pump having distal and proximal manifolds that are connected by a cylinder having a piston reciprocating therein and dividing the cylinder into a proximal and distal chambers. The manifolds have chambers that are in fluid communication with the distal and proximal chambers of the cylinder and one way valves for controlling fluid flow from and to the cylinder chambers.
摘要翻译：具有远端和近端歧管的双作用活塞血泵，其通过具有往复运动的活塞的气缸连接并将气缸分成近端和远端腔室。歧管具有与气缸的远端和近端腔室流体连通的腔室，以及用于控制流体流向气缸室的单向阀。

2. 发明授权

US5647847A Balloon catheter with improved pressure source 失效
标题翻译：球囊导管具有改善的压力源
公开(公告)号：US5647847A
公开(公告)日：1997-07-15
申请号：US334831
申请日：1994-11-04
申请人： Daniel M. Lafontaine , Daniel O. Adams , John W. Humphrey
发明人： Daniel M. Lafontaine , Daniel O. Adams , John W. Humphrey
IPC分类号： A61M25/00 , A61F2/958 , A61M29/00
CPC分类号： A61M25/10185 , A61M25/1018 , A61M25/10188 , A61M2025/0063 , A61M2025/0098 , A61M2025/1077
摘要： A balloon catheter which has an elongate shaft with an inflatable balloon connected to its distal end and a manifold connected to its proximal end. The manifold may be fixedly or removably attached to the shaft and includes a barrel with a plunger movably disposed inside it. The manifold may be held with one hand and the plunger may be actuated with one finger or thumb on the same hand. The barrel may have an internal volume of less than 5 cc and an internal diameter of less than 0.25 inches. The catheter also has a prep port which may be connected at or near the proximal end of the catheter. The prep port facilitates prepping of the catheter system. A seal (e.g. a releasable cap or a valve) may be connected to the prep port for sealing off the prep port during use. A pressure transducer may be mounted to the catheter (e.g. on the shaft, the manifold, the prep port, or the seal) to permit measurement of the pressure within the inflation lumen and the balloon. The pressure transducer may be operably connected to a pressure display and the display may be connected to the proximal end of the catheter or may be remotely located from the catheter. Data may be transmitted to the remote display by wire or wireless transmission (e.g. infrared, radio frequency, or magnetic transmission). Alternate embodiments and methods of use are also disclosed.
摘要翻译：一种气囊导管，其具有连接到其远端的可膨胀气囊的细长轴和连接到其近端的歧管。歧管可以固定地或可移除地附接到轴上并且包括具有可移动地设置在其内的柱塞的筒。歧管可以用一只手握住，并且柱塞可以用一只手指或拇指在同一只手上致动。枪管可具有小于5cc的内部容积和小于0.25英寸的内径。该导管还具有可在导管的近端处或其附近连接的制备端口。准备端口有利于导管系统的准备。可以将密封件（例如可释放盖或阀）连接到准备端口，以在使用期间密封准备端口。压力换能器可以安装到导管（例如在轴，歧管，制备端口或密封件上），以允许测量充气腔和气囊内的压力。压力传感器可以可操作地连接到压力显示器，并且显示器可以连接到导管的近端，或者可以远离导管定位。数据可以通过有线或无线传输（例如红外线，射频或磁性传输）发送到远程显示器。还公开了替代实施例和使用方法。

3. 发明授权

US5501228A Vibration sensing guide wire 失效
标题翻译：振动传感导丝
公开(公告)号：US5501228A
公开(公告)日：1996-03-26
申请号：US278552
申请日：1994-07-21
申请人： Daniel M. Lafontaine , Roger Hastings , Daniel O. Adams
发明人： Daniel M. Lafontaine , Roger Hastings , Daniel O. Adams
IPC分类号： A61B5/026 , A61B5/11 , A61B17/00 , A61B17/22 , A61M29/02 , A61B5/00
CPC分类号： A61B5/11 , A61B17/22 , A61B5/026 , A61B5/7405 , A61B2017/00022 , A61B2017/00115 , A61B2017/22001 , A61B2017/22038 , A61B5/6851 , A61M25/104
摘要： A percutaneous transluminal device for sensing the mechanical vibrations imparted to it inside a patient's vascular system. The preferred embodiments include a transducer attached to the distal end of a flexible guide wire. The transducer senses mechanical vibrations imparted to the guide wire in vivo and generates a corresponding electronic signal. Devices are provided for generating an audio or visual representation of the electronic signal.
摘要翻译：一种用于感测在患者血管系统内部向其施加的机械振动的经皮腔内装置。优选实施例包括附接到柔性导丝的远端的换能器。换能器感测在体内施加到导丝的机械振动并产生相应的电子信号。提供了用于产生电子信号的音频或视觉表示的设备。

4. 发明授权

US06190354B1 Balloon catheter with improved pressure source 失效
标题翻译：球囊导管具有改善的压力源
公开(公告)号：US06190354B1
公开(公告)日：2001-02-20
申请号：US08812285
申请日：1997-03-06
申请人： Jonathan C. Sell , John E. Arnold , Daniel M. Lafontaine , John W. Humphrey , Daniel O. Adams , Steven P. Mertens
发明人： Jonathan C. Sell , John E. Arnold , Daniel M. Lafontaine , John W. Humphrey , Daniel O. Adams , Steven P. Mertens
IPC分类号： A61M2900
CPC分类号： A61M25/10184 , A61M25/10187 , A61M25/104 , A61M2025/0001 , A61M2025/0003 , A61M2205/3331
摘要： A balloon catheter which has an elongate shaft with an inflatable balloon connected to its distal end and a manifold connected to its proximal end. The manifold may be fixedly or removably attached to the shaft and includes a barrel with a plunger movably disposed inside it. The barrel has an internal volume of less than 5 cc and an internal diameter of less than 0.25 inches. A pressure transducer may be mounted to the manifold to permit measurement via a sensor tube. A pressure source for a balloon catheter including a barrel with a plunger inside it. The barrel is in fluid communication with the inflation lumen of the catheter and has an internal volume less than 5 cc and an internal diameter of less than 0.25 inches. A pressure sensor may be connected to the barrel with a sensor tube defining a fluid path from the interior of the barrel to the pressure sensor. A lock mechanism may be connected to the barrel to control longitudinal movement of the plunger. Pressure sources for balloon catheters with an adjusted P/&Dgr;V of 4000 atm/cu.in. or more and preferably 6000 atm/cu.in. or more over a pressure range of 5 to 15 atm. Connection tubes for connecting a pressure source to a balloon catheter with an adjusted P/&Dgr;V of 6000 atm/cu.in. or more (or an adjusted P/&Dgr;V by unit length of 90×103 atm/sq.in. or more) and preferably 8000 atm/cu.in. or more (or an adjusted P/&Dgr;V by unit length of 110×103 atm/sq.in. or more) over a pressure range of 5 to 15 atm.
摘要翻译：一种气囊导管，其具有连接到其远端的可膨胀气囊的细长轴和连接到其近端的歧管。歧管可以固定地或可移除地附接到轴上并且包括具有可移动地设置在其内的柱塞的筒。桶的内部容积小于5cc，内径小于0.25英寸。压力传感器可以安装到歧管以允许通过传感器管进行测量。一种用于球囊导管的压力源，包括其中具有柱塞的筒体。筒与导管的膨胀腔流体连通，并且具有小于5cc的内部容积和小于0.25英寸的内径。压力传感器可以与限定从筒体内部到压力传感器的流体路径的传感器管连接到筒体。锁定机构可以连接到枪管以控制柱塞的纵向运动。用于具有4000atm / cu.in的调节的P / DELTAV的球囊导管的压力源。以上，优选为6000atm / cu。或更大的压力范围在5至15个大气压的连接管。用于将压力源连接到具有6000atm / cu.in调节的P / DELTAV的球囊导管的连接管。或更高（或调整后的P / DELTAV，单位长度为90×10 3 atm / sq.in以上），优选为8000atm / cu.in。以上（或调整后的P / DELTAV，单位长度为110×10 3 atm / sq.in以上）在5〜15atm的压力范围内。

5. 发明授权

US5318533A Balloon catheter inflation device including apparatus for monitoring and wireless transmission of inflation data, and system 失效
标题翻译：球囊导管充气装置，包括用于监测和无线传输通气数据的装置，以及系统
公开(公告)号：US5318533A
公开(公告)日：1994-06-07
申请号：US839628
申请日：1992-02-21
申请人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
发明人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
IPC分类号： A61F2/958 , A61M29/00 , A61M5/00
CPC分类号： A61M25/10184 , A61M25/1018 , A61M25/10182 , A61M25/104 , A61M2205/50 , Y10S128/903
摘要： An inflation device includes a syringe forming a cylindrical chamber containing a plunger carrying a stopper or piston arrangement. The chamber is designed to contain an inflation fluid and is in fluid communication with the lumen of a balloon catheter. Movement of the plunger within the chamber will increase or decrease the pressure of the fluid within the chamber and lumen, thereby inflating or deflating the balloon at the distal end of the catheter. A pressure sensor is mounted to the housing in fluid communication with the lumen and is electrically connected to a battery-operated transmitter. The transmitter broadcasts signals representing pressure within the lumen and balloon to a remote receiver. The receiver includes a microprocessor containing a clock and operable to display time and pressure data. A flexible insulator strip is interposed between the battery and the transmitter circuit to prevent operation of the transmitter until desired by the cardiologist. The housing of the inflation device may be opened to remove the batteries for separate disposal and to render the circuit inoperative to prevent reuse. A look-up table associated with the microprocessor permits display of balloon diameter during the procedure.
摘要翻译：膨胀装置包括一个注射器，该注射器形成一个圆筒形腔室，该圆柱形腔室包含一个承载塞子或腔室被设计成容纳充气流体并且与球囊导管的内腔流体连通。柱塞在腔室内的运动将增加或减小腔室和腔内的流体的压力，从而在导管的远端处膨胀或放气气囊。压力传感器安装到外壳上，与腔体流体连通，并与电池供电的变送器电连接。发射机将表示内腔和气球内的压力的信号广播到远程接收器。接收机包括一个包含时钟并可操作以显示时间和压力数据的微处理器。在电池和发射器电路之间插入柔性绝缘体条，以防止发射器的操作，直到心脏病专家期望。可以打开充气装置的壳体以移除电池以进行单独处理，并使电路不起作用以防再次使用。与微处理器相关联的查找表允许在该过程期间显示气球直径。

6. 发明申请

US20120053615A1 RAPID EXCHANGE CATHETERS USABLE WITH EMBOLIC PROTECTION DEVICES 有权
标题翻译：快速交换电缆可用于嵌入式保护装置
公开(公告)号：US20120053615A1
公开(公告)日：2012-03-01
申请号：US13223774
申请日：2011-09-01
申请人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
发明人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
IPC分类号： A61B17/22
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/008
摘要： Catheters, assemblies, and methods for delivering and recovering embolic protection devices. Catheters are provided that can be advanced over single length guide wires and which can be retracted over single length wire shafts of distal embolic protection devices. One catheter is a two-port catheter having two sidewall ports, a distal end port, and a proximal end port. The two-port catheter can be advanced over a guide wire threaded between the distal end port and the distal sidewall port. An embolic protection device wire shaft can be back loaded into the distal end port and out the proximal sidewall port. A three-port catheter includes a distal end port, and distal, intermediate, and proximal sidewall ports.
摘要翻译：用于输送和恢复栓塞保护装置的导管，组件和方法。提供导管，其可以在单长导丝上前进，并且可以在远端栓塞保护装置的单长丝线轴上缩回。一个导管是具有两个侧壁端口，远端端口和近端端口的双端口导管。双端口导管可以在远端端口和远端侧壁端口之间的引导线上前进。栓塞保护装置线轴可以被背负载到远端端口中并且从近端侧壁端口出来。三端口导管包括远端端口以及远端，中间和近端侧壁端口。

7. 发明申请

US20110283871A1 BRANCHED STENT/GRAFT AND METHOD OF FABRICATION 有权
标题翻译：分支支架/格子和制造方法
公开(公告)号：US20110283871A1
公开(公告)日：2011-11-24
申请号：US13197526
申请日：2011-08-03
申请人： Daniel O. Adams
发明人： Daniel O. Adams
IPC分类号： D04C1/00
CPC分类号： A61F2/90 , A61F2/06 , A61F2002/065 , A61F2220/0075 , A61F2230/001 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： Branched braided stent or graft devices and processes for fabrication of the devices are disclosed in which a trunk portion and two hinge leg portions are fabricated in one piece braided from a single plurality of filaments, whereby the legs contain the full plurality of filaments and the trunk portion contains a subset of the same plurality of filaments. The fabrication process involves braiding the hinged legs on a mandrel while retaining loops of filament between the hinged leg portions for subsequent braiding of the trunk portion of the stent or graft.
摘要翻译：公开了分支编织支架或移植装置以及用于制造装置的方法，其中主体部分和两个铰链腿部由单个多根细丝编成一体制成，由此腿部包含完整的多根细丝，躯干部分包含相同多个细丝的子集。制造过程包括将铰链腿编织在心轴上，同时将细丝圈保持在铰链腿部之间，以便随后编织支架或移植物的躯干部分。

8. 发明申请

US20090082803A1 BRAIDED VASCULAR DEVICES HAVING NO END CLAMPS 审中-公开
标题翻译：具有无末端束的BRAIDED血管装置
公开(公告)号：US20090082803A1
公开(公告)日：2009-03-26
申请号：US11861954
申请日：2007-09-26
申请人： Daniel O. Adams , Paul Pignato
发明人： Daniel O. Adams , Paul Pignato
IPC分类号： A61B17/03
CPC分类号： A61B17/12113 , A61B17/0057 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00615 , A61B2017/00623 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095
摘要： In some embodiments, a medical device may include one or more of the following features: (a) a metal fabric formed of braided metal strands, (b) the medical device having a collapsed configuration for delivery through a channel in a patient's body and having a generally dumbbell-shaped expanded configuration with two expanded diameter portions separated by a reduced diameter portion formed between opposed ends of the device and unsecured metal strand ends at the opposed ends, and (d) a thrombogenic agent located on the metal fabric.
摘要翻译：在一些实施例中，医疗装置可以包括以下特征中的一个或多个：（a）由编织的金属线形成的金属织物，（b）医疗装置具有用于通过患者体内的通道递送的收缩构型，通常哑铃形的扩张构型具有两个扩展直径部分，该两个扩展直径部分由形成在装置的相对端部之间的直径减小的部分和在相对端处的不牢固的金属股末端分开，以及（d）位于金属织物上的血栓形成剂。

9. 发明申请

US20090005847A1 Branched stent/graft and method of fabrication 有权
标题翻译：分支支架/移植物和制造方法
公开(公告)号：US20090005847A1
公开(公告)日：2009-01-01
申请号：US11823430
申请日：2007-06-27
申请人： Daniel O. Adams
发明人： Daniel O. Adams
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/06 , A61F2002/065 , A61F2220/0075 , A61F2230/001 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： Branched braided stent or graft devices and processes for fabrication of the devices are disclosed in which a trunk portion and two hinge leg portions are fabricated in one piece braided from a single plurality of filaments, whereby the legs contain the full plurality of filaments and the trunk portion contains a subset of the same plurality of filaments. The fabrication process involves braiding the hinged legs on a mandrel while retaining loops of filament between the hinged leg portions for subsequent braiding of the trunk portion of the stent or graft.
摘要翻译：公开了分支编织支架或移植装置以及用于制造装置的方法，其中主体部分和两个铰链腿部由单个多根细丝编成一体制成，由此腿部包含完整的多根细丝，躯干部分包含相同多个细丝的子集。制造过程包括将铰链腿编织在心轴上，同时将细丝圈保持在铰链腿部之间，以便随后编织支架或移植物的躯干部分。

10. 发明授权

US07192434B2 Vascular protection devices and methods of use 有权
标题翻译：血管保护装置及使用方法
公开(公告)号：US07192434B2
公开(公告)日：2007-03-20
申请号：US10132562
申请日：2002-04-25
申请人： Kent D. Anderson , John Oslund , Richard S. Kusleika , Daniel O. Adams
发明人： Kent D. Anderson , John Oslund , Richard S. Kusleika , Daniel O. Adams
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12172 , A61B17/221 , A61B2017/00867 , A61B2017/22045 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/008 , A61F2230/0093 , A61M25/0074 , A61M25/0082 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： An embolic protection device or system for use in a lumen of a vessel in a patient's vascular system. The device filters debris and blood clots in a body lumen and/or prevents them from moving distally from a treatment site in a vessel and causing emboli. The device may include a filter placed distally of the treatment site. The device may include an occlusive element placed either distally or proximally of the treatment site.
摘要翻译：一种用于患者血管系统中血管内腔的栓塞保护装置或系统。该装置过滤器体内的碎屑和血块，和/或阻止它们远离血管内的治疗部位并引起栓塞。该装置可以包括放置在治疗部位的远侧的过滤器。该装置可以包括放置在治疗部位的远侧或近端的闭塞元件。

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