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1. 发明授权

US06443158B1 Percutaneous coronary artery bypass through a venous vessel 失效
标题翻译：经皮冠状动脉旁路穿过静脉血管
公开(公告)号：US06443158B1
公开(公告)日：2002-09-03
申请号：US09088496
申请日：1998-06-01
申请人： Daniel M. LaFontaine , Kent D. Harrison , Chad J. Kugler , John M. K. Daniel
发明人： Daniel M. LaFontaine , Kent D. Harrison , Chad J. Kugler , John M. K. Daniel
IPC分类号： A61B1900
CPC分类号： A61B17/11 , A61B18/1492 , A61B2017/00243 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/22067 , A61B2018/00023 , A61B2018/00261 , A61B2018/00386
摘要： A bypass system for bypassing a restriction in a parent vessel of a mammal to provide blood flow past the restriction. The bypass system couples a restricted artery to a venous vessel distal of a restriction to provide blood flow through the artery distal of the restriction. Blood flow is provided to a distal portion of the artery through an adjacent venous vessel so that blood can be provided to distal portions of the restricted artery.
摘要翻译：用于绕过哺乳动物的母体血管中的限制以提供血液流过限制的旁路系统。旁路系统将限制性动脉连接到限制器远端的静脉血管，以提供通过限制远端的动脉的血液流动。通过相邻的静脉血管将动脉血流提供到动脉的远端部分，以便可以将血液提供到受限动脉的远端部分。

2. 发明授权

US6092526A Percutaneous chamber-to-artery bypass 失效
标题翻译：经皮腔至动脉旁路
公开(公告)号：US6092526A
公开(公告)日：2000-07-25
申请号：US878804
申请日：1997-06-19
申请人： Daniel M. LaFontaine , Roger N. Hastings , Thomas R. Hektner , Chad J. Kugler
发明人： Daniel M. LaFontaine , Roger N. Hastings , Thomas R. Hektner , Chad J. Kugler
IPC分类号： A61B17/00 , A61B17/11 , A61F2/02 , A61B19/00
CPC分类号： A61B17/11 , A61F2/2493 , A61B2017/00243 , A61B2017/00247 , A61B2017/1107 , A61B2017/1135 , A61B2018/00392
摘要： A vessel lies adjacent heart tissue, and a restriction in the vessel is bypassed. A chamber in the heart is accessed and a lumen is formed through the heart tissue which communicates with the vessel and a region distal to the restriction. Blood flows from the heart chamber into the vessel distal the restriction, thus bypassing the restriction.
摘要翻译：血管位于心脏组织附近，并绕过血管中的限制。进入心脏中的腔室，通过与容器连通的心脏组织和远离限制区域的区域形成管腔。血液从心脏腔室流入远离限制的血管，从而绕过限制。

3. 发明授权

US5785685A Balloon catheter with improved pressure source 失效
标题翻译：球囊导管具有改善的压力源
公开(公告)号：US5785685A
公开(公告)日：1998-07-28
申请号：US812390
申请日：1997-03-05
申请人： Chad J. Kugler , Daniel M. LaFontaine
发明人： Chad J. Kugler , Daniel M. LaFontaine
IPC分类号： A61M25/00 , A61F2/958 , A61M29/00
CPC分类号： A61M25/10185 , A61M25/1018 , A61M25/10187 , A61M25/1025 , A61M2025/0063 , A61M2025/0098 , A61M2025/1056 , A61M2025/1077
摘要： A balloon catheter is disclosed which includes a contrast displacement rod at least partially and slidably disposed in an elongate tubular member with a balloon connected to the distal end of the tubular member. The rod may include a stop mechanism to inhibit removal of the rod from the tubular member. A seal connected to the proximal end of the tubular member creates a liquid tight seal between the inside of the tubular member and the displacement rod. Accordingly, longitudinal actuation of the displacement rod causes the balloon to expand and/or contract. The balloon catheter may be a fixed wire, an over-the-wire or a single-operator exchange type balloon catheter. In addition, a pressure gauge may be connected to the proximal end of the tubular member. A one-way valve is also disclosed which allows the balloon catheter to be prepped via the guide wire lumen. Accordingly, the present invention negates the need for both an inflation device and an inflation lumen which results in a significant improvement in catheter performance and cost savings.
摘要翻译：公开了一种气囊导管，其包括至少部分且可滑动地设置在细长管状构件中的造影位移杆，其中球囊连接到管状构件的远端。杆可以包括阻止杆从管状构件移除的止动机构。连接到管状构件的近端的密封件在管状构件的内部和位移杆之间形成液体密封。因此，位移杆的纵向致动导致气囊膨胀和/或收缩。球囊导管可以是固定线，线上或单操作者交换型球囊导管。此外，压力计可以连接到管状构件的近端。还公开了允许通过导丝管腔准备球囊导管的单向阀。因此，本发明不需要充气装置和充气腔，这导致导管性能和成本节省的显着改善。

4. 发明授权

US5695468A Balloon catheter with improved pressure source 失效
标题翻译：球囊导管具有改善的压力源
公开(公告)号：US5695468A
公开(公告)日：1997-12-09
申请号：US586514
申请日：1996-01-16
申请人： Daniel M. Lafontaine , Chad J. Kugler , Matthew M. Burns
发明人： Daniel M. Lafontaine , Chad J. Kugler , Matthew M. Burns
IPC分类号： A61M25/00 , A61F2/958 , A61M29/00
CPC分类号： A61M25/10186 , A61M25/1018 , A61M25/10187 , A61M25/1025 , A61M2025/0063 , A61M2025/0098 , A61M2025/1056 , A61M2025/1077
摘要： A balloon catheter is disclosed which includes a fluid displacement rod at least partially and slidably disposed in an elongate tubular member with a balloon connected to the distal end of the tubular member. A seal connected to the proximal end of the tubular member creates a liquid tight seal between the inside of the tubular member and the displacement rod. Accordingly, longitudinal actuation of the displacement rod causes the balloon to expand and/or contract. The balloon catheter may be a fixed wire, an over-the-wire or a single-operator exchange type balloon catheter. In addition, a pressure gauge may be connected to the proximal end of the tubular member. A one-way valve is also disclosed which allows the balloon catheter to be prepped via the guide wire lumen. Accordingly, the present invention negates the need for both an inflation device and an inflation lumen which results in a significant improvement in catheter performance and cost savings.
摘要翻译：公开了一种气囊导管，其包括至少部分且可滑动地设置在细长管状构件中的流体移动杆，其中球囊连接到管状构件的远端。连接到管状构件的近端的密封件在管状构件的内部和位移杆之间形成液体密封。因此，位移杆的纵向致动导致气囊膨胀和/或收缩。球囊导管可以是固定线，线上或单操作者交换型球囊导管。此外，压力计可以连接到管状构件的近端。还公开了允许通过导丝管腔准备球囊导管的单向阀。因此，本发明不需要充气装置和充气腔，这导致导管性能和成本节省的显着改善。

5. 发明申请

US20130103070A1 ENDOVASCULAR DEVICES AND METHODS FOR EXPLOITING INTRAMURAL SPACE 有权
标题翻译：内窥镜装置及其方法
公开(公告)号：US20130103070A1
公开(公告)日：2013-04-25
申请号：US13660919
申请日：2012-10-25
申请人： Chad J. Kugler , Robert E. Atkinson , Matthew J. Olson
发明人： Chad J. Kugler , Robert E. Atkinson , Matthew J. Olson
IPC分类号： A61B17/34
CPC分类号： A61B17/3403 , A61B17/00008 , A61B17/22031 , A61B17/221 , A61B17/32053 , A61B17/32075 , A61B17/320758 , A61B17/3415 , A61B17/3417 , A61B17/3476 , A61B2017/00252 , A61B2017/003 , A61B2017/00455 , A61B2017/00685 , A61B2017/22034 , A61B2017/22038 , A61B2017/22044 , A61B2017/22077 , A61B2017/22094 , A61B2017/22095 , A61B2017/2212 , A61B2017/320004 , A61B2017/320044 , A61B2017/320064 , A61B2017/320741 , A61B2017/3405 , A61B2017/3454 , A61F2/88 , A61M25/003 , A61M25/0032 , A61M25/0045 , A61M25/0069 , A61M25/007 , A61M25/0074 , A61M25/0082 , A61M25/0152 , A61M25/04 , A61M25/10 , A61M2025/006 , A61M2025/018 , A61M2025/09175 , A61M2025/09191 , A61M2025/105
摘要： Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a re-entry device, and re-entering the true vascular lumen.
摘要翻译：提供了用于治疗慢性完全闭塞的装置和方法。一个公开的实施例包括一种便于通过限定其中包含闭塞的血管腔的血管壁进行治疗的方法。所述方法包括将血管内腔插入壁内交叉装置，至少将交叉装置的远端定位在血管壁中，使取向装置在交叉装置上方推进，使定向装置的定向元件驻留在血管壁插入再输入装置，并重新进入真正的血管腔。

6. 发明授权

US08187164B2 Methods and apparatus for treating body tissue sphincters and the like 有权
标题翻译：用于治疗身体组织括约肌等的方法和装置
公开(公告)号：US08187164B2
公开(公告)日：2012-05-29
申请号：US12610633
申请日：2009-11-02
申请人： Chad J. Kugler , Jerome K. Grudem, Jr. , Todd A. Berg , William J. Swanson
发明人： Chad J. Kugler , Jerome K. Grudem, Jr. , Todd A. Berg , William J. Swanson
IPC分类号： A61F2/00 , A61F13/00
CPC分类号： A61B17/12009 , A61B17/12013 , A61B2017/00827 , A61B2017/00876 , A61B2017/12018 , A61F2/0036 , A61F5/005 , A61F5/0069
摘要： A plurality of structures that resiliently attract one another are provided for implanting in a patient around a body tissue structure of the patient. For example, the body tissue structure may be the esophagus, and the plurality of structures may be implanted in an annulus around the outside of the esophagus, the annulus being substantially coaxial with the esophagus. The attraction may be between annularly adjacent ones of the structures in the annulus, and it may be provided, for example, by magnets or springs. The array of structures is preferably self-limiting with respect to the smallest area that it can encompass, and this smallest area is preferably large enough to prevent the apparatus from applying excessive pressure to tissue passing through that area.
摘要翻译：提供弹性地彼此吸引的多个结构，用于将患者周围的身体组织结构植入患者体内。例如，身体组织结构可以是食道，并且可以将多个结构植入围绕食管外侧的环带中，环与食道基本上同轴。吸引物可以在环形结构中的环形相邻结构之间，并且其可以例如由磁体或弹簧提供。结构的阵列优选地相对于其可以包围的最小面积是自限制的，并且该最小面积优选地足够大以防止装置对通过该区域的组织施加过大的压力。

7. 发明申请

US20100076573A1 METHODS AND APPARATUS FOR TREATING BODY TISSUE SPHINCTERS AND THE LIKE 有权
标题翻译：用于治疗身体组织细胞的方法和装置
公开(公告)号：US20100076573A1
公开(公告)日：2010-03-25
申请号：US12610633
申请日：2009-11-02
申请人： Chad J. Kugler , Jerome K. Grudem, JR. , Todd A. Berg , William J. Swanson
发明人： Chad J. Kugler , Jerome K. Grudem, JR. , Todd A. Berg , William J. Swanson
IPC分类号： A61F2/04 , A61B17/08
CPC分类号： A61B17/12009 , A61B17/12013 , A61B2017/00827 , A61B2017/00876 , A61B2017/12018 , A61F2/0036 , A61F5/005 , A61F5/0069
摘要： A plurality of structures that resiliently attract one another are provided for implanting in a patient around a body tissue structure of the patient. For example, the body tissue structure may be the esophagus, and the plurality of structures may be implanted in an annulus around the outside of the esophagus, the annulus being substantially coaxial with the esophagus. The attraction may be between annularly adjacent ones of the structures in the annulus, and it may be provided, for example, by magnets or springs. The array of structures is preferably self-limiting with respect to the smallest area that it can encompass, and this smallest area is preferably large enough to prevent the apparatus from applying excessive pressure to tissue passing through that area.
摘要翻译：提供弹性地彼此吸引的多个结构，用于将患者周围的身体组织结构植入患者体内。例如，身体组织结构可以是食道，并且可以将多个结构植入围绕食管外侧的环带中，环与食道基本上同轴。吸引物可以在环形结构中的环形相邻结构之间，并且其可以例如由磁体或弹簧提供。结构的阵列优选地相对于其可以包围的最小面积是自限制的，并且该最小面积优选地足够大以防止装置对通过该区域的组织施加过大的压力。

8. 发明授权

US06790222B2 Endovascular graft system 有权
标题翻译：血管内移植系统
公开(公告)号：US06790222B2
公开(公告)日：2004-09-14
申请号：US10341814
申请日：2003-01-14
申请人： Chad J. Kugler , John R. Drontle , Matthew J. Olson , Thomas K. Heiland , Peter T. Keith
发明人： Chad J. Kugler , John R. Drontle , Matthew J. Olson , Thomas K. Heiland , Peter T. Keith
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2/954 , A61F2002/067 , A61F2002/075 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054 , A61F2230/008
摘要： The invention provides an endovascular graft system for repair of aneurysms. The graft system includes a trunk component and first and second leg components. The graft components include graft material supported by a plurality of stents which are spaced apart and affixed to the graft material in a manner that allows articulation of the graft system without excessive wear of the graft material. The stents are formed by intersecting struts which may be tapered to relieve stress. A stabilizing mechanism is provided to stabilize the position of the legs with respect to the trunk when the graft system is deployed.
摘要翻译：本发明提供了用于修复动脉瘤的血管内移植物系统。移植物系统包括躯干部件和第一和第二腿部部件。移植物组分包括由多个支架支撑的移植材料，所述支架间隔开并且以允许移植物系统的关节连接并且固定到移植物材料上而不会过度磨损移植材料的方式。支架由相交的支柱形成，支柱可以是锥形的以减轻压力。提供了一种稳定机构，用于在移植系统展开时使腿相对于躯干的位置稳定。

9. 发明授权

US06652572B2 Endovascular graft system 有权
公开(公告)号：US06652572B2
公开(公告)日：2003-11-25
申请号：US09928790
申请日：2001-08-13
申请人： Chad J. Kugler , John R. Drontle , Peter T. Keith
发明人： Chad J. Kugler , John R. Drontle , Peter T. Keith
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/065 , A61F2002/075 , A61F2002/8486 , A61F2230/0054 , A61F2250/0039
摘要： The invention provides an attachment member for anchoring a graft system at a desired location in a vessel of a patient's vascular system. The attachment member comprises a cranial zone having a first radial strength, a caudal zone having a second radial strength, and an intermediate zone having multiple joining longitudinal struts located between and connecting the cranial and caudal zones. The intermediate zone has a third radial strength which is less than the first and second radial strengths, and the cranial and caudal zones are formed from a self-expanding material capable of expanding from a first delivery configuration to a second deployed configuration. The invention also provides an endovascular graft system, a method for deploying an aortic attachment member, and a method for repairing an aneurysm in an aorta.

10. 发明授权

US10888354B2 Endovascular devices and methods for exploiting intramural space 有权
公开(公告)号：US10888354B2
公开(公告)日：2021-01-12
申请号：US11984668
申请日：2007-11-20
申请人： Chad J. Kugler , Matthew J. Olson , Ross A. Olson , Robert E. Atkinson
发明人： Chad J. Kugler , Matthew J. Olson , Ross A. Olson , Robert E. Atkinson
IPC分类号： A61B17/34 , A61B17/221 , A61B17/3207 , A61B17/00 , A61B17/22 , A61B17/3205 , A61B17/32
摘要： Devices and methods for exploiting intramural (e.g., subintimal) space of a vascular wall to facilitate the treatment of vascular disease, particularly total occlusions. For example, the devices and methods disclosed herein may be used to visually define the vessel wall boundary, protect the vessel wall boundary from perforation, bypass an occlusion, and/or remove an occlusion.

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