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1. 发明授权

US08361381B2 Medical implants having a porous coated surface 有权
标题翻译：具有多孔涂层表面的医用植入物
公开(公告)号：US08361381B2
公开(公告)日：2013-01-29
申请号：US12506737
申请日：2009-07-21
申请人： Daniel A. Heuer , Vivek Pawar , Marcus Lee Scott , Shilesh C. Jani
发明人： Daniel A. Heuer , Vivek Pawar , Marcus Lee Scott , Shilesh C. Jani
IPC分类号： B22F7/04
CPC分类号： B22F3/15 , B22F7/004 , B22F7/08 , B22F2999/00 , B22F2201/10 , B22F2201/03
摘要： A process for making a diffusion hardened medical implant having a porous surface is disclosed. The medical implant is made by a hot isostatic pressing process which simultaneously forms that porous surface and the diffusion hardened surface.
摘要翻译：公开了一种用于制造具有多孔表面的扩散硬化医疗植入物的方法。医用植入物通过热等静压法同时形成多孔表面和扩散硬化表面。

2. 发明申请

US20100074789A1 MEDICAL IMPLANTS HAVING A POROUS COATED SUFACE 有权
标题翻译：具有多孔涂层表面的医用植入物
公开(公告)号：US20100074789A1
公开(公告)日：2010-03-25
申请号：US12506737
申请日：2009-07-21
申请人： DANIEL A. HEUER , Vivek Pawar , Marcus L. Scott , Shilesh C. Jani
发明人： DANIEL A. HEUER , Vivek Pawar , Marcus L. Scott , Shilesh C. Jani
IPC分类号： B22F7/04
CPC分类号： B22F3/15 , B22F7/004 , B22F7/08 , B22F2999/00 , B22F2201/10 , B22F2201/03
摘要： A process for making a diffusion hardened medical implant having a porous surface is disclosed. The medical implant is made by a hot isostatic pressing process which simultaneously forms that porous surface and the diffusion hardened surface.
摘要翻译：公开了一种用于制造具有多孔表面的扩散硬化医疗植入物的方法。医用植入物通过热等静压法同时形成多孔表面和扩散硬化表面。

3. 发明授权

US07968209B2 Diffusion-hardened medical implant 有权
标题翻译：扩散硬化医疗植入物
公开(公告)号：US07968209B2
公开(公告)日：2011-06-28
申请号：US12244492
申请日：2008-10-02
申请人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
发明人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
IPC分类号： B32B15/04
CPC分类号： A61L27/10 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/38 , A61F2/44 , A61F2002/30016 , A61F2002/30922 , A61F2002/30929 , A61F2210/0076 , A61F2250/0019 , A61F2250/0041 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00089 , A61F2310/00101 , A61F2310/00485 , A61F2310/00592 , A61F2310/00598 , A61F2310/00856 , A61L27/045 , A61L27/047 , A61L27/06 , A61L27/30 , A61L27/50 , A61L2400/00 , Y10T428/12611
摘要： The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition.
摘要翻译：本发明涉及由其制成的新组合物和医用植入物，所述组合物包含厚扩散硬化区，并且优选还包含陶瓷层。本发明涉及包括新组合物的矫形植入物，制备新组合物的方法，以及制备包含该新组合物的整形外科植入物的方法。

4. 发明申请

US20110139312A1 METHOD OF PROVIDING A ZIRCONIUM SURFACE AND RESULTING PRODUCT 有权
标题翻译：提供ZIRCONIUM表面和结果产品的方法
公开(公告)号：US20110139312A1
公开(公告)日：2011-06-16
申请号：US12971933
申请日：2010-12-17
申请人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
发明人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
IPC分类号： B32B15/04 , C22C45/10
CPC分类号： A61L27/306 , A61F2/30 , A61F2002/30024 , A61F2002/30026 , C22C45/10 , C23C8/02 , C23C8/10 , C23C30/00
摘要： A coating of blue-black or black zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the treatment of an amorphous zirconium or zirconium alloy substrate, which may have an altered surface roughness. The treatment of amorphous zirconium or zirconium alloy substrates includes oxidation of the substrates. A zirconium coating of uniform and controlled thickness is especially useful in various applications because the uniformly thick zirconium surface of controlled depth provide a barrier against implant corrosion caused by ionization of the metal substrates.
摘要翻译：通过处理可能具有改变的表面粗糙度的无定形锆或锆合金基底来实现在锆或锆合金材料上具有均匀和受控厚度的蓝黑色或黑色锆的涂层。无定形锆或锆合金基底的处理包括基底的氧化。均匀和受控厚度的锆涂层在各种应用中特别有用，因为受控深度的均匀厚的锆表面提供了抵抗由金属基底的电离引起的植入物腐蚀的屏障。

5. 发明授权

US10675384B2 Surface alloyed medical implant 有权
公开(公告)号：US10675384B2
公开(公告)日：2020-06-09
申请号：US12811672
申请日：2009-01-02
申请人： Vivek Pawar , Donald E. Kramer , Carolyn L. Weaver , Shilesh C. Jani
发明人： Vivek Pawar , Donald E. Kramer , Carolyn L. Weaver , Shilesh C. Jani
IPC分类号： A61F2/28 , A61L27/50 , A61L27/04 , A61L27/30
摘要： A medical implant is disclosed. The medical implant includes: a first biocompatible metal forming a substrate (210, 310, 410), a second biocompatible metal diffused into the first biocompatible metal to form an biocompatible alloy surface (220, 314, 414), the alloy surface further including a diffusion hardening species, wherein the diffusion hardening species may be carbon, nitrogen, oxygen, boron, or any combination thereof. A method of forming a medical implant is also disclosed. The method includes the steps of: providing a first biocompatible metal or alloy that forms a substrate (210, 310, 410), providing a second biocompatible metal or alloy, diffusing the second biocompatible metal into the first biocompatible metal to form an alloy layer (220, 314, 414), removing excess second metal material from the substrate to expose the alloy layer, and diffusion hardening the alloy layer.

6. 发明授权

US07473278B2 Method of surface oxidizing zirconium and zirconium alloys and resulting product 有权
标题翻译：表面氧化锆和锆合金及所得产品的方法
公开(公告)号：US07473278B2
公开(公告)日：2009-01-06
申请号：US10942464
申请日：2004-09-16
申请人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
发明人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
IPC分类号： A61F2/30 , A61F2/28
CPC分类号： A61L27/306 , A61F2/30 , A61F2002/30024 , A61F2002/30026 , C22C45/10 , C23C8/02 , C23C8/10 , C23C30/00
摘要： A coating of blue-black or black oxidized zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the oxidative treatment of an amorphous zirconium or zirconium alloy substrate having an altered surface roughness. An oxidized zirconium coating of uniform and controlled thickness is especially useful on orthopedic implants of zirconium or zirconium-based alloys to provide low friction, highly wear resistant surfaces on artificial joints, such as, but not limited to, hip joints, knee joints, shoulders, elbows, and spinal implants. The uniformly thick oxidized zirconium surface of controlled depth on prostheses provide a barrier against implant corrosion caused by ionization of the metal prostheses. The invention is also useful in non-articulating implant devices such as bone plates, bone screws, etc.
摘要翻译：锆或锆合金材料上均匀且受控厚度的蓝黑色或黑色氧化锆涂层是通过氧化处理具有改变的表面粗糙度的无定形锆或锆合金基材来完成的。均匀和受控厚度的氧化锆涂层特别适用于锆或锆基合金的矫形植入物，以在人造关节上提供低摩擦，高耐磨性表面，例如但不限于髋关节，膝关节，肩部，肘部和脊柱植入物。在假体上的受控深度的均匀厚的氧化锆表面提供了抵抗由金属假体的电离引起的植入物腐蚀的屏障。本发明也可用于非关节式植入装置，例如骨板，骨螺钉等。

7. 发明申请

US20080289729A1 DIFFUSION-HARDENED MEDICAL IMPLANT 有权
标题翻译：扩散硬化医疗植物
公开(公告)号：US20080289729A1
公开(公告)日：2008-11-27
申请号：US12127413
申请日：2008-05-27
申请人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
发明人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
IPC分类号： C21D9/00 , A61F2/00
CPC分类号： A61L27/10 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/38 , A61F2/44 , A61F2002/30016 , A61F2002/30922 , A61F2002/30929 , A61F2210/0076 , A61F2250/0019 , A61F2250/0041 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00089 , A61F2310/00101 , A61F2310/00485 , A61F2310/00592 , A61F2310/00598 , A61F2310/00856 , A61L27/045 , A61L27/047 , A61L27/06 , A61L27/30 , A61L27/50 , A61L2400/00 , Y10T428/12611
摘要： The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition.
摘要翻译：本发明涉及由其制成的新组合物和医用植入物，所述组合物包含厚扩散硬化区，并且优选还包含陶瓷层。本发明涉及包括新组合物的矫形植入物，制备新组合物的方法，以及制备包含该新组合物的整形外科植入物的方法。

8. 发明授权

US07896926B2 Method of surface oxidizing zirconium and zirconium alloys and resulting product 有权
标题翻译：表面氧化锆和锆合金及所得产品的方法
公开(公告)号：US07896926B2
公开(公告)日：2011-03-01
申请号：US12277013
申请日：2008-11-24
申请人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
发明人： Gordon Hunter , Shilesh C. Jani , Vivek Pawar
IPC分类号： A61F2/28 , A61F2/32
CPC分类号： A61L27/306 , A61F2/30 , A61F2002/30024 , A61F2002/30026 , C22C45/10 , C23C8/02 , C23C8/10 , C23C30/00
摘要： A coating of blue-black or black oxidized zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the oxidative treatment of an amorphous zirconium or zirconium alloy substrate having an altered surface roughness. An oxidized zirconium coating of uniform and controlled thickness is especially useful on orthopedic implants of zirconium or zirconium-based alloys to provide low friction, highly wear resistant surfaces on artificial joints, such as, but not limited to, hip joints, knee joints, shoulders, elbows, and spinal implants. The uniformly thick oxidized zirconium surface of controlled depth on prostheses provide a barrier against implant corrosion caused by ionization of the metal prostheses. The invention is also useful in non-articulating implant devices such as bone plates, bone screws, etc.
摘要翻译：通过氧化处理具有改变的表面粗糙度的无定形锆或锆合金基材，可以在锆或锆合金材料上形成均匀和受控厚度的蓝黑色或黑色氧化锆涂层。均匀和受控厚度的氧化锆涂层特别适用于锆或锆基合金的矫形植入物，以在人造关节上提供低摩擦，高耐磨性表面，例如但不限于髋关节，膝关节，肩部，肘部和脊柱植入物。在假体上的受控深度的均匀厚的氧化锆表面提供了抵抗由金属假体的电离引起的植入物腐蚀的屏障。本发明也可用于非关节式植入装置，例如骨板，骨螺钉等。

9. 发明申请

US20110015756A1 SURFACE ALLOYED MEDICAL IMPLANT 审中-公开
标题翻译：表面合金医疗植物
公开(公告)号：US20110015756A1
公开(公告)日：2011-01-20
申请号：US12811672
申请日：2009-01-02
申请人： Vivek Pawar , Donald E. Kramer , Carolyn L. Weaver , Shilesh C. Jani
发明人： Vivek Pawar , Donald E. Kramer , Carolyn L. Weaver , Shilesh C. Jani
IPC分类号： A61F2/28 , B05D7/00
CPC分类号： A61L27/50 , A61L27/04 , A61L27/306 , A61L2400/18
摘要： A medical implant is disclosed. The medical implant includes: a first biocompatible metal forming a substrate (210, 310, 410), a second biocompatible metal diffused into the first biocompatible metal to form an biocompatible alloy surface (220, 314, 414), the alloy surface further including a diffusion hardening species, wherein the diffusion hardening species may be carbon, nitrogen, oxygen, boron, or any combination thereof. A method of forming a medical implant is also disclosed. The method includes the steps of: providing a first biocompatible metal or alloy that forms a substrate (210, 310, 410), providing a second biocompatible metal or alloy, diffusing the second biocompatible metal into the first biocompatible metal to form an alloy layer (220, 314, 414), removing excess second metal material from the substrate to expose the alloy layer, and diffusion hardening the alloy layer.
摘要翻译：公开了一种医疗植入物。医疗植入物包括：形成基底（210,310,410）的第一生物相容性金属，扩散到第一生物相容性金属中以形成生物相容性合金表面（220,314,414）的第二生物相容性金属，所述合金表面还包括扩散硬化物质，其中扩散硬化物质可以是碳，氮，氧，硼或其任何组合。还公开了一种形成医疗植入物的方法。该方法包括以下步骤：提供形成基材（210,310,410）的第一生物相容性金属或合金，提供第二生物相容性金属或合金，将第二生物相容性金属扩散到第一生物相容性金属中以形成合金层（从衬底去除多余的第二金属材料以暴露合金层，并扩散硬化合金层。

10. 发明申请

US20070137734A1 Diffusion-Hardened Medical Implant 有权
标题翻译：扩散硬化医学植入物
公开(公告)号：US20070137734A1
公开(公告)日：2007-06-21
申请号：US11558756
申请日：2006-11-10
申请人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
发明人： Vivek Pawar , Shilesh C. Jani , Carolyn Weaver
IPC分类号： A61F2/30 , A61F2/28 , C22F1/18
CPC分类号： A61L27/10 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/38 , A61F2/44 , A61F2002/30016 , A61F2002/30922 , A61F2002/30929 , A61F2210/0076 , A61F2250/0019 , A61F2250/0041 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00089 , A61F2310/00101 , A61F2310/00485 , A61F2310/00592 , A61F2310/00598 , A61F2310/00856 , A61L27/045 , A61L27/047 , A61L27/06 , A61L27/30 , A61L27/50 , A61L2400/00 , Y10T428/12611
摘要： The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition.
摘要翻译：本发明涉及由其制成的新组合物和医用植入物，所述组合物包含厚扩散硬化区，并且优选还包含陶瓷层。本发明涉及包括新组合物的矫形植入物，制备新组合物的方法，以及制备包含该新组合物的整形外科植入物的方法。

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