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1. 发明申请

WO2004012794A8 IMPLANTABLE FLOW REGULATOR WITH FAILSAFE MODE AND RESERVE DRUG SUPPLY 审中-公开
标题翻译：具有故障安全模式和储备药物供应的植入式流量调节器
公开(公告)号：WO2004012794A8
公开(公告)日：2004-06-10
申请号：PCT/US0228575
申请日：2002-09-06
申请人： DURECT CORP , POUTIATINE ANDREW I , GILLIS EDWARD M , MAEUSLI PIERRE-ALAIN , GASS VOLKER
发明人： POUTIATINE ANDREW I , GILLIS EDWARD M , MAEUSLI PIERRE-ALAIN , GASS VOLKER
IPC分类号： A61M5/168 , A61M39/28 , A61M5/00
CPC分类号： A61M5/16877 , A61M5/16881 , A61M39/28
摘要： An implantable flow regulator (22) for regulating flow of a drug along a drug delivery pathway (14) form a drug source to a treatment site within a subject includes a movable diversion member (24) and an actuator. The movable diversion member (24) is operably coupled to a delivery pathway (14). The actuator is actuatable to move the diversion member (24) between at least a first mode position where the diversion member (24) restricts flow through the delivery pathway (14) (i.e., delivery pathway is "closed"), and a second mode position where the diversion member (24) is positioned to allow flow through the delivery pathway (14) (i.e., delivery pathway is "open"). Supplying power to actuate the actuator moves the diversion member (24) from its normally biased first mode or "closed" position, which is also a failsafe position, toward its second mode or "open" position. In the "open" position, drug is supplied to target sites, typically from a drug supply reserve within the regulator.
摘要翻译：用于调节药物沿着药物输送通道（14）的药物流动的可植入流量调节器（22）形成到对象内治疗部位的药物源，包括可移动转向构件（24）和致动器。可移动转向构件（24）可操作地联接到输送通道（14）。致动器可致动以在至少第一模式位置和第二模式之间移动分流构件24，在第一模式位置中分流构件24限制通过输送通路14的流动（即输送通路“关闭”），（24）定位成允许流过输送通道（14）（即输送通道“打开”）的位置。提供致动致动器的动力将分流构件24从其正常偏置的第一模式或“关闭”位置（其也是故障安全位置）朝向其第二模式或“打开”位置移动。在“开放”的位置，药物通常来自监管机构内的药物供应储备，供应给目标地点。

2. 发明申请

WO2004022130A3 AUTONOMOUS PATCH FOR COMMUNICATION WITH AN IMPLANTABLE DEVICE, AND MEDICAL KIT FOR USING SAID PATCH 审中-公开
标题翻译：用于与植入式装置通信的自动补丁，以及用于使用所述补丁的医疗工具包
公开(公告)号：WO2004022130A3
公开(公告)日：2004-05-13
申请号：PCT/US0327862
申请日：2003-09-05
申请人： DURECT CORP
发明人： GASS VOLKER , GILLIS EDWARD M
IPC分类号： A61M20060101 , A61N1/08 , A61N1/372 , A61N1/378
CPC分类号： A61N1/37235 , A61N1/3787
摘要： The present invention is directed to a self contained control patch for an implanted medical device, comprising a housing capable of being removably associated with an external surface of a patient, a transmitter for transmitting at least one of a transcutaneous power signal and a transcutaneous control signal to an implanted device; and a pre-programmed storage device containing at least one control program, wherein the control program dictates the nature of the signal from the transmitting means. Additionally, the present invention is directed to a system of such patches comprising two or more patches, with each patch being pre-programmed with a discrete set of instructions. Methods for using the patches are additionally disclosed.
摘要翻译：本发明涉及一种用于植入的医疗装置的独立控制贴片，其包括能够可移除地与患者的外表面相关联的壳体，用于发送经皮功率信号和经皮控制信号中的至少一个的发射器到植入装置; 以及包含至少一个控制程序的预先编程的存储设备，其中控制程序指示来自发送装置的信号的性质。另外，本发明涉及这种贴片的系统，其包括两个或更多个贴片，每个贴片用一组离散的指令预先编程。另外公开了使用贴剂的方法。

3. 发明公开

EP1534361A4 IMPLANTABLE FLOW REGULATOR WITH FAILSAFE MODE AND RESERVE DRUG SUPPLY 审中-公开
标题翻译：失败保护模式IMPLANTIEBARER流量控制器和备用药品供应
公开(公告)号：EP1534361A4
公开(公告)日：2010-07-07
申请号：EP02807653
申请日：2002-09-06
申请人： DURECT CORP
发明人： POUTIATINE ANDREW I , GILLIS EDWARD M , MAEUSLI PIERRE-ALAIN , GASS VOLKER
IPC分类号： A61M5/168 , A61M39/28 , A61M5/00
CPC分类号： A61M5/16877 , A61M5/16881 , A61M39/28

4. 发明专利

AU2003265944A8 Autonomous patch for communication with an implantable device, and medical kit for using said patch 未知
公开(公告)号：AU2003265944A8
公开(公告)日：2004-03-29
申请号：AU2003265944
申请日：2003-09-05
申请人： DURECT CORP
发明人： GASS VOLKER , GILLIS EDWARD M
IPC分类号： A61M20060101 , A61N1/08 , A61N1/372 , A61N1/378
摘要： The present invention is directed to a self contained control patch for an implanted medical device, comprising a housing capable of being removably associated with an external surface of a patient, a transmitter for transmitting at least one of a transcutaneous power signal and a transcutaneous control signal to an implanted device; and a pre-programmed storage device containing at least one control program, wherein the control program dictates the nature of the signal from the transmitting means. Additionally, the present invention is directed to a system of such patches comprising two or more patches, with each patch being pre-programmed with a discrete set of instructions. Methods for using the patches are additionally disclosed.

5. 发明专利

AU2003265944A1 AUTONOMOUS PATCH FOR COMMUNICATION WITH AN IMPLANTABLE DEVICE, AND MEDICAL KIT FOR USING SAID PATCH 未知
公开(公告)号：AU2003265944A1
公开(公告)日：2004-03-29
申请号：AU2003265944
申请日：2003-09-05
申请人： DURECT CORP
发明人： GASS VOLKER , GILLIS EDWARD M
IPC分类号： A61M20060101 , A61N1/08 , A61N1/372 , A61N1/378
摘要： The present invention is directed to a self contained control patch for an implanted medical device, comprising a housing capable of being removably associated with an external surface of a patient, a transmitter for transmitting at least one of a transcutaneous power signal and a transcutaneous control signal to an implanted device; and a pre-programmed storage device containing at least one control program, wherein the control program dictates the nature of the signal from the transmitting means. Additionally, the present invention is directed to a system of such patches comprising two or more patches, with each patch being pre-programmed with a discrete set of instructions. Methods for using the patches are additionally disclosed.

6. 发明专利

AU2002332928A1 IMPLANTABLE FLOW REGULATOR WITH FAILSAFE MODE AND RESERVE DRUG SUPPLY 未知
公开(公告)号：AU2002332928A1
公开(公告)日：2004-02-23
申请号：AU2002332928
申请日：2002-08-06
申请人： DURECT CORP
发明人： MAUSLI PIERRE-ALAIN , GASS VOLKER , POUTIATINE ANDREW I , GILLIS EDWARD M
IPC分类号： A61M5/168 , A61M39/28 , A61M5/00

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