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    • 1. 发明申请
    • HIGH VISCOSITY ANTIBACTERIALS
    • 高粘度抗菌剂
    • WO2007016410A2
    • 2007-02-08
    • PCT/US2006029568
    • 2006-07-28
    • DSU MED CORPUTTERBERG DAVID SSWINDLER FRED G
    • UTTERBERG DAVID SSWINDLER FRED G
    • A61K9/14A61K31/045
    • A61K31/045A61K9/0014A61K9/0019A61K47/10A61K47/34
    • An antibacterial fluid may be applied to a tubular medical cannula for access to a patient. The fluid comprises a typically metabolizable antibacterial formulation having a viscosity preferably greater than 150,000 cp. The cannula may then be inserted into the patient with an increased lubricity for a reduction of pain, while at the same time, unlike silicones, preferred materials do not readily accumulate in the patient. The fluid may be placed on the skin. The tubular medical cannula may be a rigid, hollow needle, sharp or blunt, a spike, or a flexible catheter. Also, the viscous antibacterial fluid may be used to lock a catheter or other cannula while implanted in the patient, for storage purposes. The formulation is typically an alcohol plus a viscosity increasing agent and optionally a surfactant, a clotting agent, and/or EDTA.
    • 抗菌流体可以施加到管状医疗插管以接近患者。 该流体包含具有优选大于150,000cp的粘度的典型可代谢抗菌制剂。 然后插管可以以增加的润滑性插入患者以减轻疼痛,同时,与聚硅氧烷不同,优选的材料不容易积聚在患者体内。 流体可以放置在皮肤上。 管状医用插管可以是刚性的空心针,尖锐的或钝的,尖刺或柔性导管。 而且,为了储存目的,粘性抗菌流体可以用于在植入患者体内时锁定导管或其他套管。 该制剂通常是醇加增粘剂和任选的表面活性剂,凝结剂和/或EDTA。