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    • 3. 发明申请
    • TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE
    • 在头发护理中使用史蒂芬或衍生物
    • WO2012010624A3
    • 2012-09-27
    • PCT/EP2011062425
    • 2011-07-20
    • DSM IP ASSETS BVGORALCZYK REGINAGRAEUB REMOMAYNE-MECHAN ANNIS OLIVIAPIUSSI JENNYRIEGER HENRYMOHAJERI HASAN
    • GORALCZYK REGINAGRAEUB REMOMAYNE-MECHAN ANNIS OLIVIAPIUSSI JENNYRIEGER HENRYMOHAJERI HASAN
    • A61K8/365A61K8/60A61Q5/00A61Q7/00
    • A61K8/365A61Q5/00A61Q5/002A61Q5/006A61Q5/06A61Q5/065A61Q5/10A61Q5/12A61Q7/00A61Q17/00
    • The present invention relates to the use of steviol and/or isosteviol, or a salt, ester, a diester, or an ether thereof as depicted in formula (I), formula (I): R1 wherein R1 is hydrogen (H) or a saturated, straight or branched C1-C8 alkyl group non substituted or substituted with up to 3 hydroxyl-, alkoxy-, amino-, alkylamino- or dialkylamino- groups, R2 is independently a saturated, straight or branched C1-C8 alkyl group, -O-C1-C8 alkyl group, -OH group, a -O-C(O)-C1-C8 alkyl, or, -COO(C1-C8 alkyl) group, R3 is independently CH2, O, or CH-(C1-C7 alkyl), wherein the enhancement of the appearance of hair is selected from the group consisting of: restoring hair color and delaying the onset of greyness in hair, lessening hair loss, restoring hair growth after the onset of baldness has occurred, increasing the thickness of hair, counteracting age-associated hair thinning, preventing premature hair loss, or delaying the onset or severity of age-associated hair loss and thinning, maintaining of the natural hair colour, increasing hair shininess, glossiness or volume. In particular, the compound is applied topically.
    • 本发明涉及式(I),式(I)所示的甜菊醇和/或异硬脂醇或其盐,酯,二酯或其醚的用途:其中R1是氢(H)或 未被取代或被至多3个羟基,烷氧基,氨基,烷基氨基或二烷基氨基取代的饱和,直链或支链C 1 -C 8烷基,R 2独立地为饱和的,直链或支链的C 1 -C 8烷基, O-C 1 -C 8烷基,-OH基团,-OC(O)-C 1 -C 8烷基或-COO(C 1 -C 8烷基)基团,R 3独立地是CH 2,O或CH-(C 1 -C 7 烷基),其中提高毛发的外观选自:恢复头发颜色并延迟头发中的灰色发作,减少脱发,恢复发秃后恢复毛发生长,增加毛发的厚度 头发,抵抗年龄相关的头发变薄,防止过早的脱发,或延迟年龄相关脱发和变薄的发作或严重程度,维持 g的天然头发颜色,增加头发光泽,光泽度或体积。 特别地,化合物局部施用。