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1. 发明申请

WO2006114439A2 NOVEL NUTRACEUTICAL COMPOSITIONS 审中-公开
标题翻译：新型营养成分
公开(公告)号：WO2006114439A2
公开(公告)日：2006-11-02
申请号：PCT/EP2006061874
申请日：2006-04-27
申请人： DSM IP ASSETS BV , EDENS LUPPO , WOLFRAM SWEN , VAN PLATERINK CHRISTIANUS JACO , GERHARDT CINDERELLA CHRISTINA
发明人： EDENS LUPPO , WOLFRAM SWEN , VAN PLATERINK CHRISTIANUS JACO , GERHARDT CINDERELLA CHRISTINA
IPC分类号： A61K38/06 , A61P3/10 , A61P9/12
CPC分类号： A61Q19/00 , A23J3/344 , A23K20/147 , A23L33/18 , A23V2002/00 , A61K8/64 , A61K38/06 , C07K5/0808 , C07K5/081 , C12Y304/15001 , A23V2200/328 , A23V2250/0626 , A23V2250/0648 , A23V2250/064 , A23V2200/326 , A23V2250/0632 , A23V2250/0604
摘要： The present invention describes the use of MAP and/or ITP or a salt thereof as a nutraceutical, preferably a medicament.
摘要翻译：本发明描述了MAP和/或ITP或其盐作为营养食品，优选药物的用途。

2. 发明申请

WO2007088062A3 FOOD PRODUCT COMPRISING A PROLINE SPECIFIC PROTEASE 审中-公开
标题翻译：含有PROLINE SPECIFIC PROTEASE的食品
公开(公告)号：WO2007088062A3
公开(公告)日：2008-09-12
申请号：PCT/EP2007000896
申请日：2007-01-30
申请人： DSM IP ASSETS BV , EDENS LUPPO , DE DECKERE EMILE
发明人： EDENS LUPPO , DE DECKERE EMILE
IPC分类号： A23L1/305 , A23J3/00 , C12N9/00 , C12P31/00
CPC分类号： C12N9/62 , A23D7/001 , A23L2/52 , A23L21/10 , A23L27/60 , A23L29/06 , A23L33/18 , A23V2002/00 , C12Y304/14002 , C12Y304/14005 , C12Y304/21026 , A23V2200/18 , A23V2200/32
摘要： The present invention relates to a pasteurized food product having a water activity of at least 0.80, preferably at least 0.85 and containing a proline specific protease.
摘要翻译：本发明涉及一种具有至少0.80，优选至少0.85的水分活性并含有脯氨酸特异性蛋白酶的巴氏杀菌食品。

3. 发明申请

WO2009083411A2 USES FOR AQUEOUS STREAMS CONTAINING PROTEINS 审中-公开
标题翻译：用于含有蛋白质的水溶液
公开(公告)号：WO2009083411A2
公开(公告)日：2009-07-09
申请号：PCT/EP2008067168
申请日：2008-12-10
申请人： DSM IP ASSETS BV , BROECKE VAN DEN PIETER MARINUS , EDENS LUPPO , ROOS DE ANDRE LEONARDUS
发明人： BROECKE VAN DEN PIETER MARINUS , EDENS LUPPO , ROOS DE ANDRE LEONARDUS
IPC分类号： A23J1/16 , A23J1/12 , A23J3/34
CPC分类号： A23J3/346 , A23K20/147 , A23L33/175 , A23L33/18 , A23V2002/00 , A23V2200/316 , A23V2250/548 , A23V2200/328
摘要： The present invention relates to a protein hydrolysate comprising free amino acids and peptides whereby the weight ratio of free amino acids to peptides is about 1 :1 and wherein at least about 50 molar % of the peptides has a molecular weight of 400 Da or less. This composition may be rich in one or more branched- chain amino acid- (BCAA-) and/or glutamine-containing di- or tripeptides. Also, the invention relates to the use of a water soluble protein-containing aqueous fraction obtained from a wet-milling process or the protein hydrolysate in: the manufacture of a medicament for the treatment or prevention of a condition associated with inappropriate blood sugar metabolism; aiding recovery and/or endurance during or after exercise; stimulating the generation of lean body mass; infant nutrition; or the preparation of a food or feed composition or a food or feed supplement.
摘要翻译：本发明涉及包含游离氨基酸和肽的蛋白质水解物，其中游离氨基酸与肽的重量比为约1:1，其中至少约50摩尔％的肽具有400Da或更小的分子量。该组合物可以富含一个或多个支链氨基酸 - （BCAA-）和/或含谷氨酰胺的二肽或三肽。此外，本发明涉及在湿法研磨或蛋白质水解产物中得到的含水溶性蛋白质的水性组分的用途：制备用于治疗或预防与不适当的血糖代谢有关的病症的药物; 在运动期间或之后协助康复和/或耐力; 刺激瘦体重的产生; 婴幼儿营养; 或制备食物或饲料组合物或食品或饲料补充剂。

4. 发明申请

WO2006005757A3 BLOOD PRESSURE LOWERING OLIGOPEPTIDES 审中-公开
标题翻译：血压下降低血糖
公开(公告)号：WO2006005757A3
公开(公告)日：2007-03-15
申请号：PCT/EP2005053336
申请日：2005-07-12
申请人： DSM IP ASSETS BV , EDENS LUPPO , ROOS DE ANDRE LEONARDUS , HOEVEN VAN DER ROBERTUS ANTONI , DEEN PHILIPPUS ANTONIUS
发明人： EDENS LUPPO , ROOS DE ANDRE LEONARDUS , HOEVEN VAN DER ROBERTUS ANTONI , DEEN PHILIPPUS ANTONIUS
IPC分类号： C12P21/06 , A61K38/06
CPC分类号： C12P21/06 , A61K38/06
摘要： The present invention describes a process to produce IPP from a protein source whereby the ratio of IPP and VPP produced from the protein is at least 5, preferably at least 10 and more preferably at least 20, which comprises the use of a proline specific endoprotease.
摘要翻译：本发明描述了从蛋白质源产生IPP的方法，其中由蛋白质产生的IPP和VPP的比例为至少5，优选至少10，更优选至少为20，其包括使用脯氨酸特异性内切蛋白酶。

5. 发明申请

WO2009083411A3 USES FOR AQUEOUS STREAMS CONTAINING PROTEINS 审中-公开
标题翻译：用于含蛋白质的水流
公开(公告)号：WO2009083411A3
公开(公告)日：2009-10-01
申请号：PCT/EP2008067168
申请日：2008-12-10
申请人： DSM IP ASSETS BV , BROECKE VAN DEN PIETER MARINUS , EDENS LUPPO , ROOS DE ANDRE LEONARDUS
发明人： BROECKE VAN DEN PIETER MARINUS , EDENS LUPPO , ROOS DE ANDRE LEONARDUS
IPC分类号： A23J1/16 , A23J1/12 , A23J3/34
CPC分类号： A23J3/346 , A23K20/147 , A23L33/175 , A23L33/18 , A23V2002/00 , A23V2200/316 , A23V2250/548 , A23V2200/328
摘要： The present invention relates to a protein hydrolysate comprising free amino acids and peptides whereby the weight ratio of free amino acids to peptides is about 1:1 and wherein at least about 50 molar % of the peptides has a molecular weight of 400 Da or less. This composition may be rich in one or more branched- chain amino acid- (BCAA-) and/or glutamine-containing di- or tripeptides. Also, the invention relates to the use of a water soluble protein-containing aqueous fraction obtained from a wet-milling process or the protein hydrolysate in: the manufacture of a medicament for the treatment or prevention of a condition associated with inappropriate blood sugar metabolism; aiding recovery and/or endurance during or after exercise; stimulating the generation of lean body mass; infant nutrition; or the preparation of a food or feed composition or a food or feed supplement.
摘要翻译：本发明涉及包含游离氨基酸和肽的蛋白质水解产物，其中游离氨基酸与肽的重量比为约1：1，并且其中至少约50摩尔％的肽具有400Da或更小的分子量。该组合物可富含一种或多种支链氨基酸 - （BCAA-）和/或含谷氨酰胺的二肽或三肽。此外，本发明涉及由湿磨工艺获得的含水溶蛋白的水性部分或蛋白质水解产物在制备用于治疗或预防与不适当的血糖代谢相关的病症的药物中的用途; 帮助锻炼期间或之后的恢复和/或耐力; 刺激瘦体重的产生; 婴儿营养; 或制备食物或饲料组合物或食物或饲料补充剂。

6. 发明申请

WO2007107587A3 CHOLESTEROL LOWERING PROTEIN HYDROLYSATES 审中-公开
标题翻译：胆固醇降低蛋白水解酶
公开(公告)号：WO2007107587A3
公开(公告)日：2008-04-10
申请号：PCT/EP2007052694
申请日：2007-03-21
申请人： DSM IP ASSETS BV , EDENS LUPPO , RAEDERSTORFF DANIEL
发明人： EDENS LUPPO , RAEDERSTORFF DANIEL
IPC分类号： C07K7/06 , A61K38/04 , A61K38/07 , A61K38/08 , A61K38/10 , C07K5/10 , C07K7/08
CPC分类号： C07K5/1008 , C07K5/1019 , C07K5/1024
摘要： The present invention relates to the production of novel peptides which have a length of between 4 and 8 amino acids and comprises the amino acid sequence -Xaa-Xbb-Xcc-Xdd- or -Xbb-Xcc-Xdd-Xaa-, whereby Xaa and Xcc can be His (H), Arg (R) or Lys (K), and Xbb and Xdd can be Pro (P) or GIy (G).
摘要翻译：本发明涉及长度为4至8个氨基酸且包含氨基酸序列-Xaa-Xbb-Xcc-Xdd-或-Xbb-Xcc-Xdd-Xaa-的新型肽，其中Xaa和 Xcc可以是His（H），Arg（R）或Lys（K），Xbb和Xdd可以是Pro（P）或Gly（G）。

7. 发明申请

WO2007060247A2 ENZYME PREPARATIONS YIELDING A CLEAN TASTE 审中-公开
标题翻译： ENZYME准备工作一个清洁的东西
公开(公告)号：WO2007060247A2
公开(公告)日：2007-05-31
申请号：PCT/EP2006068979
申请日：2006-11-28
申请人： DSM IP ASSETS BV , SWAAF DE MAXIMILIAAN PETER MAR , DIJK VAN ALBERTUS ALARD , EDENS LUPPO , DEKKER PETRUS JACOBUS THEODORU
发明人： SWAAF DE MAXIMILIAAN PETER MAR , DIJK VAN ALBERTUS ALARD , EDENS LUPPO , DEKKER PETRUS JACOBUS THEODORU
IPC分类号： C12N9/38 , A23C9/12 , C12N1/21 , C12N15/56
CPC分类号： A23C9/127 , A23C9/1206 , A23C19/0328 , C12N9/16 , C12N9/2402 , C12N9/2468 , C12N9/2471 , C12N9/62 , C12Y301/06001 , C12Y302/01023 , C12Y302/01108
摘要： The present invention describes a intracellular produced lactase, which comprises less than 40 units arylsulfatase activity per NLU of lactase activity. The invention also provides a process comprising treating a substrate with an enzyme preparation, wherein the enzyme preparation is substantially free from arylsulfatase.
摘要翻译：本发明描述了细胞内产生的乳糖酶，其包含每NLU乳糖酶活性少于40个芳基硫酸酯酶活性。本发明还提供了一种方法，其包括用酶制剂处理底物，其中所述酶制剂基本上不含芳基硫酸酯酶。

8. 发明申请

WO2006067163A2 BLOOD PRESSURE LOWERING PEPTIDES IN A SINGLE ENZYMATIC STEP 审中-公开
标题翻译：血压降低在一个单一的步骤
公开(公告)号：WO2006067163A2
公开(公告)日：2006-06-29
申请号：PCT/EP2005057000
申请日：2005-12-21
申请人： DSM IP ASSETS BV , EDENS LUPPO , ROOS DE ANDRE LEONARDUS , SCHOUTEN OLAF LEONARDUS , DEEN PHILIPPUS ANTONIUS
发明人： EDENS LUPPO , ROOS DE ANDRE LEONARDUS , SCHOUTEN OLAF LEONARDUS , DEEN PHILIPPUS ANTONIUS
CPC分类号： C12P21/06 , A23J3/344 , A23L33/11 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K38/00 , A23V2200/3262 , A23V2200/332 , A23V2200/326 , A23V2250/54246 , A23V2250/2136 , A23V2250/7052 , A23V2250/706 , A23V2250/7056
摘要： A process to produce IPP and VPP from a protein source that comprises the -I- P-P- and -V-P-P- sequence in its protein sequence and whereby at least 40% of -I-P-P- sequence present in the protein source is converted into the peptide IPP and at least 40% of the -V-P-P- sequence present in the protein source is converted into the peptide VPP, which comprises the use of a proline specific endoprotease and an amino- peptidase preferably in a single enzymatic step.
摘要翻译：从其蛋白质序列中包含-I-PP-和-VPP-序列的蛋白质源产生IPP和VPP的过程，并且其中存在于蛋白质源中的-IPP-序列的至少40％被转化为肽IPP 并且存在于蛋白质源中的至少40％的-VPP-序列被转化为肽VPP，其包括优选在单个酶促步骤中使用脯氨酸特异性内切蛋白酶和氨基肽酶。

9. 发明申请

WO2007101888A3 IMPROVED BREWING PROCESS 审中-公开
标题翻译：改进的BREWING过程
公开(公告)号：WO2007101888A3
公开(公告)日：2007-11-08
申请号：PCT/EP2007056259
申请日：2007-06-22
申请人： DSM IP ASSETS BV , NGUYEN MINH-TAM , EDENS LUPPO , ROON VAN JEROEN LOUIS
发明人： NGUYEN MINH-TAM , EDENS LUPPO , ROON VAN JEROEN LOUIS
IPC分类号： C12C5/00 , C12C11/00 , C12H1/22 , C12N9/62
CPC分类号： C12C5/004 , C12C11/003 , C12H1/22
摘要： The present invention relates to the use of a proline-specific protease for accelerating the beer brewing process. In particular, it relates to the use of a proline-specific protease for accelerating the beer brewing process by shortening and simplifying the stabilisation phase of beer production. The stabilisation period as such can be omitted from the beer making process hereby saving significant costs and adding to the flexibility of beer producing plants.
摘要翻译：本发明涉及脯氨酸特异性蛋白酶用于加速啤酒酿造方法的用途。特别涉及脯氨酸特异性蛋白酶用于通过缩短和简化啤酒生产稳定期来加速啤酒酿造过程的用途。因此，啤酒制造过程中可以省略稳定期，从而节省了大量成本并增加了啤酒生产厂的灵活性。

10. 发明申请

WO2007079977A3 NUTRACEUTICAL COMPOSITIONS COMPRISING TRIPEPTIDES 审中-公开
标题翻译：包含TRIPEPTIDES的营养组合物
公开(公告)号：WO2007079977A3
公开(公告)日：2007-09-13
申请号：PCT/EP2006012595
申请日：2006-12-29
申请人： DSM IP ASSETS BV , EDENS LUPPO , GORALCZYK REGINA , WYSS ADRIAN
发明人： EDENS LUPPO , GORALCZYK REGINA , WYSS ADRIAN
IPC分类号： A61K38/06 , A23L1/305 , A61K45/06 , A61P25/24 , A61P25/26 , A61P25/28
CPC分类号： A61K45/06 , A23L33/18 , A61K38/06
摘要： The invention relates to a novel nutraceutical composition containing at least one tripeptide as active ingredient. The term "nutraceutical" as used herein denotes a usefulness in both the nutritional and pharmaceutical field of application. Thus, the novel nutraceutical compositions can find use as supplement to food and beverages, and as pharmaceutical formulations for enteral or parenteral application which may be solid formulations such as capsules or tablets, or liquid formulations, such as solutions or suspensions. As will be evident from the foregoing, the term nutraceutical composition also comprises food and beverages containing the above-specified active ingredients, for example protein hydrolysates which are rich in tripeptides according to the invention. The compositions are useful to improve cognitive functions such as learning, memory and alertness and for the treatment of a disorder connected to impaired neurotransmission and of conditions resulting from hypoxia and for alleviating neuropathic pain.
摘要翻译：本发明涉及含有至少一种三肽作为活性成分的新型营养组合物。本文所用的术语“营养药物”表示在营养和制药领域中的有用性。因此，新型营养食品组合物可以用作食品和饮料的补充剂，以及用作肠内或肠胃外应用的药物制剂，其可以是固体制剂如胶囊或片剂，或液体制剂，例如溶液或悬浮液。从前述可以看出，术语营养药物组合物还包括含有上述活性成分的食品和饮料，例如富含根据本发明的三肽的蛋白质水解产物。该组合物可用于改善认知功能，例如学习，记忆和警觉性，以及治疗与受损的神经传递相关的病症以及由缺氧引起的疾病和减轻神经性疼痛。

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