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1. 发明申请

WO2008119544A1 NOVEL USE OF GENISTEIN 审中-公开
标题翻译：新陈代谢的使用
公开(公告)号：WO2008119544A1
公开(公告)日：2008-10-09
申请号：PCT/EP2008/002563
申请日：2008-04-01
申请人： DSM IP ASSETS B.V. , PRUDENCE, Kevin , RIEGGER, Christoph , SCHALCH, Wolfgang
发明人： PRUDENCE, Kevin , RIEGGER, Christoph , SCHALCH, Wolfgang
IPC分类号： A61K31/352 , A61P27/02
CPC分类号： A61K31/352 , A23L33/105
摘要： Use of genistein for the treatment and prevention of dry eye syndrome or LKC and corresponding compositions containing it.
摘要翻译：使用染料木素治疗和预防干眼综合征或LKC及含有它的相应组合物。

2. 发明申请

WO2006081972A1 NOVEL COMPOSITION COMPRISING LIGUSTILIDE AND PROCESS FOR THEIR MANUFACTURE 审中-公开
标题翻译：包含LIGESTILIDE的新型组合物及其制造方法
公开(公告)号：WO2006081972A1
公开(公告)日：2006-08-10
申请号：PCT/EP2006/000648
申请日：2006-01-26
申请人： DSM IP ASSETS B.V. , PROPLESCH, Ralf , RIEGGER, Christoph , SIMON, Werner , WOLFRAM, Swen
发明人： PROPLESCH, Ralf , RIEGGER, Christoph , SIMON, Werner , WOLFRAM, Swen
IPC分类号： A61K36/236 , A61K125/00
CPC分类号： A61K36/236
摘要： Novel purified extracts from Ligusticum species are obtained by submitting crude extracts from Ligusticum species, particularly from Ligusticum wallichii (chuanxiong) containing less than 50 wt.-% of ligustilide to rectification under specific conditions.
摘要翻译：通过将含有少于50wt。％百日咳的Ligusticum wallichii（chuanxiong）的Ligusticum种的粗提取物提取到特定条件下进行精制，得到来自Ligusticum物种的新型纯化提取物。

3. 发明申请

WO2006131326A2 NOVEL USE OF (-)-EPIGALLOCATECHIN GALLATE 审中-公开
标题翻译：（ - ） - EPIGALLOCATECHIN GALLATE的新用途
公开(公告)号：WO2006131326A2
公开(公告)日：2006-12-14
申请号：PCT/EP2006/005410
申请日：2006-06-07
申请人： DSM IP ASSETS B.V. , RAEDERSTORFF, Daniel , RIEGGER, Christoph , THIELECKE, Frank
发明人： RAEDERSTORFF, Daniel , RIEGGER, Christoph , THIELECKE, Frank
IPC分类号： A61P3/04 , A61P3/06 , A61K45/06 , A61K31/352 , A61K31/522
CPC分类号： A61K45/06 , A61K31/352 , A61K31/522
摘要： The present invention refers to the use of (-)-epigallocatechin gallate, preferably in combination with a sympathomimeticum, for increasing/stimulating the fat oxidation in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans, especially during postprandial conditions; supporting the metabolization of fat in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; for reducing the weight of mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; for reducing the fat mass in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; for increasing the endurance in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; for reducing the carbohydrate oxidation in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; for reducing the respiratory quotient in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans; and for improving the flow mediated dilation, thereby contributing to the beneficial effects on coronary health, in mammals selected from the group consisting of humans, cats, dogs and horses, preferably in humans. The preferred sympathomimeticum is caffeine. The invention further refers to the corresponding methods. Preferably the (-)-epigallocatechin gallate has a purity of at least 80% or higher. More preferably it is obtained by any of the processes described in US 6,383,392, EP 1 103 550, US 10/246 112 and EP 1 077 211.
摘要翻译：本发明涉及（ - ） - 表没食子儿茶素没食子酸酯，优选与交感神经结合，用于增加/刺激选自人，猫，狗和马，优选在人中的哺乳动物中的脂肪氧化，特别是在人中餐后情况; 支持选自人，猫，狗和马的哺乳动物中的脂肪代谢，优选在人中; 用于减少选自人，猫，狗和马的哺乳动物的重量，优选在人中; 用于减少选自人，猫，狗和马的哺乳动物中的脂肪，优选在人中; 用于增加选自人，猫，狗和马的哺乳动物的耐力，优选在人中; 用于减少选自人，猫，狗和马的哺乳动物中的碳水化合物氧化，优选在人中; 用于减少选自人，猫，狗和马的哺乳动物的呼吸商，优选在人中; 并且用于改善流动介导的扩张，从而有助于对选自人，猫，狗和马，优选在人中的哺乳动物对冠状动脉健康有益的影响。首选的交感神经是咖啡因。本发明还涉及相应的方法。（ - ） - 表没食子儿茶素没食子酸酯优选具有至少80％以上的纯度。更优选地，其通过US 6,383,392，EP 1 103 550，US 10/246 112和EP 1077 211中描述的任何方法获得。

4. 发明申请

WO2007113008A2 OPAQUE CONTAINER COMPRISING FOOD OR PHARMACEUTICAL PRODUCTS OR HERBAL(S) 审中-公开
标题翻译：包含食品或药用产品或草药的OPAQUE容器（S）
公开(公告)号：WO2007113008A2
公开(公告)日：2007-10-11
申请号：PCT/EP2007/003060
申请日：2007-04-04
申请人： DSM IP ASSETS B.V. , BAIER, Wiltrud , BECKER, Martina , RIEGGER, Christoph
发明人： BAIER, Wiltrud , BECKER, Martina , RIEGGER, Christoph
IPC分类号： A23L1/30 , B65D85/804 , A47J31/40 , B65D81/00 , A23F3/30 , A23F3/32 , A23F5/38 , A23F5/40 , A61K9/48
CPC分类号： A23F3/14 , A23F5/40 , A23L33/105
摘要： The present invention relates to opaque containers comprising a food product which is enriched in a physiologically active ingredient, and/or a pharmaceutical product wherein the pharmaceutical product is any product being used for the prevention or treatment of a disease of a human or any product being used for the maintenance or promotion of the/a healthy state of a human. The present invention furthermore relates to the manufacture of such opaque containers and to their use for the preparation of ready-to-drink/eat food or pharmaceutical products.
摘要翻译：本发明涉及包含富含生理活性成分的食品的不透明容器和/或药物产品，其中药物产品是用于预防或治疗人类疾病或任何产品的任何产品用于维护或促进人的健康状态。本发明还涉及这种不透明容器的制造及其用于制备即饮饮料/食用食品或药品的用途。

5. 发明申请

WO2007113007A2 PACKAGE CONTAINING (A PLANT EXTRACT COMPRISING) A POLYPHENOL AND THEIR USES 审中-公开
标题翻译：包装（包括植物提取物）聚苯醚及其用途
公开(公告)号：WO2007113007A2
公开(公告)日：2007-10-11
申请号：PCT/EP2007/003054
申请日：2007-04-04
申请人： DSM IP ASSETS B.V. , BECKER, Martina , RIEGGER, Christoph
发明人： BECKER, Martina , RIEGGER, Christoph
IPC分类号： B65D51/28 , A23L1/30
CPC分类号： B65D51/2821 , A23L33/105
摘要： The invention relates to a package containing a food product and an additive composition, wherein the additive composition is separated from the food product, wherein the package comprises means (7) for releasing the additive composition into the food product, and wherein the additive composition contains a polyphenol and/or a plant extract containing a polyphenol. The invention further relates to the use of a polyphenol and/or a plant extract containing a polyphenol in a health improving and/or maintaining diet, wherein the polyphenol and/or the plant extract containing a polyphenol is provided in a package containing a food product and separated from the food product an additive composition comprising or consisting of said polyphenol and/or said plant extract containing a polyphenol and wherein the additive composition is released into the food product immediately prior to the consumption of the food product. Especially preferred polyphenols are (-)-epigallocatechin gallate, resveratrol and hydroxytyrosol.
摘要翻译：本发明涉及一种包含食品和添加剂组合物的包装，其中添加剂组合物与食品分离，其中包装包括用于将添加剂组合物释放到食品中的装置（7），并且其中添加剂组合物含有多酚和/或含有多酚的植物提取物。本发明还涉及在健康改善和/或维持饮食中含有多酚的多酚和/或植物提取物的用途，其中含有多酚的多酚和/或含有多酚的植物提取物在含有食品的包装中提供并从所述食品中分离出包含所述多酚和/或含有多酚的所述植物提取物或由所述植物提取物组成的添加剂组合物，并且其中所述添加剂组合物在食品消费之前立即释放到食品中。特别优选的多酚是（ - ） - 表没食子儿茶素没食子酸酯，白藜芦醇和羟基酪醇。

6. 发明申请

WO2008092572A1 SAUCE CONTAINING (-)-EPIQALLOCATECHIN GALLATE 审中-公开
标题翻译：包含（ - ） - EPIQALLOCATECHIN GALLATE
公开(公告)号：WO2008092572A1
公开(公告)日：2008-08-07
申请号：PCT/EP2008/000332
申请日：2008-01-17
申请人： DSM IP ASSETS B.V. , RIEGGER, Christoph , STIEFEL, Anna-Maria , WOLFRAM, Swen
发明人： RIEGGER, Christoph , STIEFEL, Anna-Maria , WOLFRAM, Swen
IPC分类号： A23L1/39 , A23L1/40 , A23L1/48
CPC分类号： A23L35/00 , A23L23/00 , A23L33/105 , A23V2002/00 , A23V2200/33 , A23V2250/214
摘要： Sauce containing (-)-epigallocatechin gallate and/or one or more of its derivatives.
摘要翻译：含有（ - ） - 表没食子儿茶素没食子酸酯和/或其一种或多种衍生物的酱汁。

7. 发明申请

WO2017097805A1 CURCUMIN AND RESVERATROL FOR CHRONIC INFLAMMATION 审中-公开
标题翻译：姜黄素和白藜芦醇对慢性炎症的治疗作用
公开(公告)号：WO2017097805A1
公开(公告)日：2017-06-15
申请号：PCT/EP2016/080014
申请日：2016-12-07
申请人： DSM IP ASSETS B.V.
发明人： BUTT, Christopher Michael , RIEGGER, Christoph , WYNALDA, Kelly
IPC分类号： A61K31/05 , A61K31/12 , A61P29/00
CPC分类号： A61K31/12 , A61K31/05 , A61K2300/00
摘要： The combination of curcumin and resveratrol can prevent the microglia from participating in the inflammation pathway in the brain. Thus this combination can reduce/prevent inflammation in the brain secondary to conditions such as obesity, diabetes, injury, and infection. The combination can also reduce chronic pain.
摘要翻译：姜黄素和白藜芦醇的组合可防止小胶质细胞参与脑中的炎症通路。因此，这种组合可以减少/预防继发于肥胖症，糖尿病，损伤和感染等病症的脑中的炎症。这种组合还可以减少慢性疼痛。

8. 发明授权

EP2129373B1 Use of genistein for treating dry eye syndrome 有权
标题翻译：使用染料木黄酮的干眼的治疗
公开(公告)号：EP2129373B1
公开(公告)日：2013-05-22
申请号：EP08716727.6
申请日：2008-04-01
申请人： DSM IP Assets B.V.
发明人： PRUDENCE, Kevin , RIEGGER, Christoph , SCHALCH, Wolfgang
IPC分类号： A61K31/352 , A61P27/02 , A23L1/29 , A23L1/30
CPC分类号： A61K31/352 , A23L33/105
摘要： Use of genistein for the treatment and prevention of dry eye syndrome or LKC and corresponding compositions containing it.

9. 发明公开

EP3386492A1 CURCUMIN AND RESVERATROL FOR CHRONIC INFLAMMATION 审中-公开
公开(公告)号：EP3386492A1
公开(公告)日：2018-10-17
申请号：EP16806143.0
申请日：2016-12-07
申请人： DSM IP Assets B.V.
发明人： BUTT, Christopher Michael , RIEGGER, Christoph , WYNALDA, Kelly
IPC分类号： A61K31/05 , A61K31/12 , A61P29/00
CPC分类号： A61K31/12 , A61K31/05 , A61P29/00 , A61K2300/00
摘要： The combination of curcumin and resveratrol can prevent the microglia from participating in the inflammation pathway in the brain. Thus this combination can reduce/prevent inflammation in the brain secondary to conditions such as obesity, diabetes, injury, and infection. The combination can also reduce chronic pain.

10. 发明授权

EP1370257B1 COMPOSITION FOR THE PREVENTION OF OSTEOPOROSIS consisting of A COMBINATION OF ISOFLAVONES AND POLYUNSATURATED FATTY ACIDS 有权
标题翻译：组成骨质疏松症的预防，包括异黄酮和多不饱和脂肪酸的组合
公开(公告)号：EP1370257B1
公开(公告)日：2007-07-25
申请号：EP02726156.9
申请日：2002-03-11
申请人： DSM IP Assets B.V.
发明人： KRAMMER, Stephanie c/o Fam. Artur Eckert , RIEGGER, Christoph , SCHLACHTER, Manfred , WEBER, Peter
IPC分类号： A61K31/353 , A61K31/19 , A61K31/593 , A61K31/122 , A61P19/10
CPC分类号： A61K31/19 , A23K20/121 , A23K20/158 , A23K20/174 , A23K50/40 , A23L33/105 , A23L33/12 , A23V2002/00 , A61K31/122 , A61K31/353 , A61K31/593 , A61K2300/00 , A23V2250/1882 , A23V2250/2116 , A23V2250/714 , A23V2250/71
摘要： A composition, useful in the prevention of osteoporosis, wherein said composition comprises (a) least one isoflavone and/or isoflavone glycoside, preferably genistein and/or genistin; (b) at least one polyunsaturated fatty acid; (c) optionally vitamin D, and /or one or more derivatives thereof and /or vitamin K and/or one or more derivatives thereof; and (d) optionally adjuvants and excipients in quantities as required, preferably within the range of 0.1 to 20 % by weight, based on the total weight of the composition. Dietary compositions and galenical forms made therefrom and the use of said compositions for preventing osteoporosis and stimulating osteogenesis in mammals.

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