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    • 2. 发明申请
    • SYSTEM AND METHOD FOR PRODUCING BEADS
    • 用于生产珠粒的系统和方法
    • US20160038898A1
    • 2016-02-11
    • US14886482
    • 2015-10-19
    • DPX Holdings B.V.
    • Allan Otto Fog LihmeMarie Bendix HansenRene Oehlenschlaeger HolteBrian A. Larsen
    • B01J2/08
    • B01J2/08B01J13/046
    • The present invention relates to a method for producing beads comprising a material capable of gelation, said method comprising the steps of: (i) combining (a) a liquid composition comprising a material capable of gelation; and (b) a first hydrophobic phase; (ii) subjecting the liquid composition and the first hydrophobic phase, to means for emulsification in a first reactor by addition of external mechanical energy creating an emulsion comprising individual droplets comprising the material capable of gelation in the first hydrophobic phase (wherein the material capable of gelation provides a discontinuous phase and the first hydrophobic phase provides a continuous phase); (iii) stabilising the droplets by transferring the emulsion from the first reactor to a stabilisation reactor wherein the emulsion obtained in step (ii) is subjected to means for gelation in order to obtain gelation within 5 minutes or less, and the beads are formed.
    • 本发明涉及包含能够凝胶化的材料的珠粒的制造方法,所述方法包括以下步骤:(i)将(a)包含能够凝胶化的材料的液体组合物组合; 和(b)第一疏水相; (ii)使液体组合物和第一疏水相经过添加外部机械能在第一反应器中进行乳化的装置,产生包含单个液滴的乳液,所述液滴包含能够在第一疏水相中凝胶化的材料(其中能够 凝胶化提供不连续相,第一疏水相提供连续相); (iii)通过将乳液从第一反应器转移到稳定反应器中来稳定液滴,其中在步骤(ii)中获得的乳液经历凝胶化手段,以在5分钟以内获得凝胶化,并形成珠粒。