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    • 3. 发明申请
    • ANALYTE EXTRACTION APPARATUS AND METHOD
    • 分析物萃取装置和方法
    • WO2012049491A2
    • 2012-04-19
    • PCT/GB2011/051958
    • 2011-10-11
    • SPHERE MEDICAL LIMITEDPETTIGREW, David MichaelLIU, BoLAITENBERGER, Peter GeorgBATES, Stephen
    • PETTIGREW, David MichaelLIU, BoLAITENBERGER, Peter GeorgBATES, Stephen
    • G01N30/06
    • G01N33/948G01N30/06G01N30/24G01N2030/067G01N2030/085Y10T436/11Y10T436/203332Y10T436/255
    • Disclosed is an apparatus for automatically extracting i2,6-diisopropylphenol (Propofol), from a complex sample matrix comprising cellular material, e.g. blood, the apparatus comprising a sample reception stage having on output for providing a defined quantity of the complex sample matrix; a mixing stage having a first input in fluidic connection with the output of the sample reception stage, a second input for receiving a lysing agent and an output for providing a mixture of the defined quantity of the complex sample matrix and the lysing agent; a delay stage having an input in fluidic connection with the output of the mixing stage and an output for providing the delayed mixture of the defined quantity of the complex sample matrix and the lysing agent; a filtering stage comprising a sorbent material for mechanically lysing the cellular material, said sorbent material having an affinity for binding Propofol, said filtering stage having an input in fluidic connection with the output of the delay stage; and a controller for controlling the flow rate of the mixture of the defined quantity of the complex sample matrix and the lysing agent through said delay stage. A method for such extraction is also disclosed.
    • 本发明公开了一种用于从包含细胞材料的复杂样品基质(例如细胞材料)自动提取1,2,6-二异丙基苯酚(丙泊酚)的装置。 所述设备包括:样本接收级,其具有用于提供限定量的所述复杂样本矩阵的输出; 混合阶段,其具有与样品接收阶段的输出物流体连接的第一输入端,用于接收裂解剂的第二输入端和用于提供限定量的复杂样品基质和裂解剂的混合物的输出端; 延迟级,其具有与混合级的输出端流体连接的输入端和用于提供限定量的复杂样品基质和裂解剂的延迟混合物的输出端; 包含用于机械裂解所述细胞材料的吸附剂材料的过滤阶段,所述吸附剂材料具有与丙泊酚结合的亲和力,所述过滤阶段具有与所述延迟阶段的输出端流体连接的输入端; 以及控制器,用于通过所述延迟阶段控制限定量的复杂样品基质和裂解剂的混合物的流速。 还公开了这种提取的方法。
    • 9. 发明申请
    • METHODS AND SYSTEMS FOR INFERRING TRAITS TO MANAGE NON-BEEF LIVESTOCK
    • 感染非营养食品的方法和系统
    • WO2005040400A2
    • 2005-05-06
    • PCT/US2004/035274
    • 2004-10-22
    • MMI GENOMICS, INC.DENISE, Sue, K.ROSENFELD, DavidKERR, RichardBATES, StephenHOLM, Tom
    • DENISE, Sue, K.ROSENFELD, DavidKERR, RichardBATES, StephenHOLM, Tom
    • C12Q
    • C12Q1/6827
    • Methods and systems are provided for managing non-beef livestock subjects in order to maximize their individual potential performance and the value of a product from the non-beef livestock subjects, and to maximize profits obtained in marketing the . non-beef livestock subjects. The methods and systems draw an inference of a trait of a non-beef livestock subject by determining the nucleotide occurrence of at least one non-beef livestock SNP that is determined to be associated with the trait. The inference is used in methods of the present invention to establish the economic value of a non-beef livestock subject, to improve profits related to selling beef from a non-beef livestock subject; to manage non-beef livestock subjects, to sort non-beef livestock subjects; to improve the genetics of a non-­beef livestock population by selecting and breeding of non-beef livestock subjects, to clone a non-beef livestock subject with a specific trait, to track meat or another commercial product of a non-beef livestock subject; and to diagnose a health condition of a non-beef livestock subject. Certain embodiments of the present invention provide methods, systems, and kits are directed to inferences of a trait related to milk or a dairy product in a livestock subject.
    • 提供方法和系统,用于管理非牛类牲畜科目,以最大限度地发挥其非牛肉牲畜品种的潜在性能和价值,并最大限度地利用营销中获得的利润。 非牛肉家畜。 方法和系统通过确定确定与性状相关联的至少一种非牛肉牲畜SNP的核苷酸发生来推断非牛肉家畜受试者的性状。 本发明的方法用于确定非牛肉主体的经济价值,提高从非牛肉牲畜中销售牛肉的利润; 管理非牛肉牲畜,对非牛肉牲畜进行分类; 通过选择和培育非牛类牲畜,通过选择具有特殊性状的非牛肉牲畜来追踪非牛肉牲畜的肉类或其他商品,改善非牛类牲畜群体的遗传学; 并诊断非牛肉牲畜的健康状况。 提供方法,系统和试剂盒的本发明的某些实施方案涉及与家畜受试者中的牛奶或乳制品相关的性状的推论。