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1. 发明专利

HK1205005A1 BONE TREATMENT SYSTEMS 未知
公开(公告)号：HK1205005A1
公开(公告)日：2015-12-11
申请号：HK15105540
申请日：2015-06-10
申请人： DFINE INC
发明人： TRUCKAI CSABA , KOHM ANDREW , SHADDUCK JOHN H , LUZZI ROBERT
IPC分类号： A61L20060101 , A61K6/884
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

2. 发明专利

AU2013240565A1 Methods and systems for use in controlling tissue ablation volume by temperature monitoring 未知
公开(公告)号：AU2013240565A1
公开(公告)日：2014-11-06
申请号：AU2013240565
申请日：2013-01-31
申请人： DFINE INC
发明人： KRAMER STEVE , KAMDAR KIRTI P , KOHM ANDREW , POSER ROBERT , GERMAIN AARON
IPC分类号： A61B18/14
摘要： This invention relates to medical methods, instruments and systems for creating a controlled lesion using temperature to control the growth of the lesion. The treatment can be used in any tissue area and is particularly useful in or around a vertebral body. The features relating to the methods and devices described herein can be applied in any region of soft or hard tissue including bone or hard tissue.

3. 发明专利

AU2013240565B2 Methods and systems for use in controlling tissue ablation volume by temperature monitoring 未知
公开(公告)号：AU2013240565B2
公开(公告)日：2017-07-20
申请号：AU2013240565
申请日：2013-01-31
申请人： DFINE INC
发明人： KRAMER STEVE , KAMDAR KIRTI P , KOHM ANDREW , POSER ROBERT , GERMAIN AARON
IPC分类号： A61B18/14
摘要： This invention relates to medical methods, instruments and systems for creating a controlled lesion using temperature to control the growth of the lesion. The treatment can be used in any tissue area and is particularly useful in or around a vertebral body. The features relating to the methods and devices described herein can be applied in any region of soft or hard tissue including bone or hard tissue.

4. 发明专利

HK1214110A1 用於將接入設備固定到椎體用於骨接合劑注入的設備、方法和系統未知
公开(公告)号：HK1214110A1
公开(公告)日：2016-07-22
申请号：HK16102005
申请日：2016-02-23
申请人： DFINE INC
发明人： PHAN CHRISTOPHER U , KOHM ANDREW , POSER ROBERT , KAMDAR KIRTI P
IPC分类号： A61B20060101

5. 发明专利

CA2868869C METHODS AND SYSTEMS FOR USE IN CONTROLLING TISSUE ABLATION VOLUME BY TEMPERATURE MONITORING 未知
公开(公告)号：CA2868869C
公开(公告)日：2021-01-12
申请号：CA2868869
申请日：2013-01-31
申请人： DFINE INC
发明人： KRAMER STEVE , KAMDAR KIRTI P , KOHM ANDREW , POSER ROBERT , GERMAIN AARON
IPC分类号： A61B18/14 , A61B8/08 , A61B8/12
摘要： This invention relates to medical methods, instruments and systems for creating a controlled lesion using temperature to control the growth of the lesion. The treatment can be used in any tissue area and is particularly useful in or around a vertebral body. The features relating to the methods and devices described herein can be applied in any region of soft or hard tissue including bone or hard tissue.

6. 发明专利

ES2483996T3 Sistemas y métodos de tratamiento de los huesos 未知
公开(公告)号：ES2483996T3
公开(公告)日：2014-08-08
申请号：ES09715413
申请日：2009-02-27
申请人： DFINE INC
发明人： TRUCKAI CSABA , KOHM ANDREW , SHADDUCK JOHN , LUZZI ROBERT
IPC分类号： A61L24/04 , A61K6/884
摘要： Una composición de cemento óseo, que comprende: Un componente monómero y una componente de polímero que, tras el mezclado, proporciona una composición de cemento óseo polimerizable, el componente de polímero comprende: un primer volumen de partículas de polímero con un diámetro en el intervalo de 100 - 120 μm, en donde el primer volumen de partículas de polímero comprende un polímero de polimetilmetacrilato (PMMA) en polvo y contiene 0.9 - 1.1% en peso de peróxido de benzoílo (BPO) en base al peso total de las primeras partículas de polímero; un segundo volumen de partículas de polímero con un diámetro en el intervalo de 70 - 90 μm, en donde el segundo volumen de partículas de polímero comprende un PMMA en polvo y contiene 1.1 - 1.3% en peso BPO en base al peso total de las segundas partículas de polímero; y un tercer volumen de partículas de polímero con un diámetro en el intervalo de 25 - 45 μm, en donde el tercer volumen de partículas de polímero comprende un PMMA en polvo y contiene 0.0 - 1.1% en peso BPO en base al peso total de las terceras partículas de polímero; en donde el componente de polímero se configura para proporcionar una exposición controlada del BPO al componente monómero para controlar la viscosidad de la composición de cemento óseo.

7. 发明专利

BR112014024028B1 Dispositivo médico para criação de regiões de tecido aquecido utilizando temperatura para monitorar um perfil desejado das regiões 未知
公开(公告)号：BR112014024028B1
公开(公告)日：2022-05-31
申请号：BR112014024028
申请日：2013-01-31
申请人： DFINE INC
发明人： GERMAIN AARON , KOHM ANDREW , KIRTI P KAMDAR , POSER ROBERT , KRAMER STEVE
IPC分类号： A61B18/14
摘要： métodos e sistemas para uso no controle de volume de ablação de tecido por monitoramento de temperatura. essa invenção se refere a métodos, instrumentos e sistemas médicos para criação de uma lesão controlada utilizando temperatura para controlar o crescimento da lesão. o tratamento pode ser utilizado em qualquer área de tecido e é particularmente útil no ou ao redor de um corpo vertebral. os aspectos referentes aos métodos e dispositivos descritos aqui podem ser aplicados em qualquer região de tecido mole ou duro incluindo osso ou tecido duro.

8. 发明专利

CA2868869A1 METHODS AND SYSTEMS FOR USE IN CONTROLLING TISSUE ABLATION VOLUME BY TEMPERATURE MONITORING 未知
公开(公告)号：CA2868869A1
公开(公告)日：2013-10-03
申请号：CA2868869
申请日：2013-01-31
申请人： DFINE INC
发明人： KRAMER STEVE , KAMDAR KIRTI P , KOHM ANDREW , POSER ROBERT , GERMAIN AARON
IPC分类号： A61B18/14
摘要： This invention relates to medical methods, instruments and systems for creating a controlled lesion using temperature to control the growth of the lesion. The treatment can be used in any tissue area and is particularly useful in or around a vertebral body. The features relating to the methods and devices described herein can be applied in any region of soft or hard tissue including bone or hard tissue.

9. 发明申请

WO2009108893A2 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2009108893A2
公开(公告)日：2009-09-03
申请号：PCT/US2009035549
申请日：2009-02-27
申请人： DFINE INC , TRUCKAI CSABA , KOHM ANDREW , SHADDUCK JOHN H , LUZZI ROBERT
发明人： TRUCKAI CSABA , KOHM ANDREW , SHADDUCK JOHN H , LUZZI ROBERT
IPC分类号： A61L24/04
CPC分类号： A61L24/0094 , A61B17/7095 , A61B17/8822 , A61B17/8833 , A61B17/8836 , A61B2017/00022 , A61K31/78 , A61L24/001 , A61L24/0084 , A61L24/0089 , A61L24/06 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
摘要翻译：本公开内容涉及具有用于椎体成形术程序和其它骨成形术程序的延长工作时间的骨水泥制剂以及水泥注射器，其包括用于按需控制水泥粘度和流动参数的能量输送系统。骨水泥制剂可以包括具有至少一种单体和包含聚合物颗粒和过氧化苯甲酰（BPO））的非液体组分的液体组分。非液体组分可以进一步构造成允许BPO受控地暴露于液体单体，以便能够控制骨水泥组合物的粘度。

10. 发明公开

EP2931144A4 DEVICES, METHODS AND SYSTEMS FOR AFFIXING AN ACCESS DEVICE TO A VERTEBRAL BODY FOR THE INSERTION OF BONE CEMENT 有权
标题翻译：设备，方法和系统，用于固定在椎体接入设备安装骨水泥
公开(公告)号：EP2931144A4
公开(公告)日：2016-10-26
申请号：EP13862396
申请日：2013-12-12
申请人： DFINE INC
发明人： PHAN CHRISTOPHER U , KOHM ANDREW , POSER ROBERT , KAMDAR KIRTI P
IPC分类号： A61B17/16 , A61B17/56 , A61B17/58 , A61B17/60 , A61B17/88
CPC分类号： A61B17/8811 , A61B17/8805 , A61B17/8808 , A61B17/8816
摘要： Devices and method discussed for device for delivering a pressurized substance to an opening in bone within a vertebral column, useful to provide access to structures in the vertebral so that a substance, such as bone cement can be delivered through a lumen or portal or for providing access to the opening in bone by a separate instrument.
摘要翻译：设备和方法，用于将加压物质在开口在骨中的脊柱内递送到，有用的是提供进入结构在椎体所以没有的物质，颜色讨论了设备：如骨水泥可通过内腔或门户或用于提供递送访问由单独的仪器在骨中的开口。

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