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    • 8. 发明申请
    • METHOD AND APPARATUS FOR REALISTIC SIMULATION OF WRINKLE AGING AND DE-AGING
    • 用于真实模拟老化和衰老的方法和装置
    • WO2009014832A2
    • 2009-01-29
    • PCT/US2008067516
    • 2008-06-19
    • PROCTER & GAMBLEHILLEBRAND GREGDEMIRLI RAMAZAN
    • HILLEBRAND GREGDEMIRLI RAMAZAN
    • G06T11/60G06T7/00
    • G06T7/33G06T11/60G06T2207/20021G06T2207/30088G06T2207/30201
    • Methods and systems are disclosed to realistically simulate facial wrinkle aging of a person using a neutral state (natural look) image and one or more expression images (e.g., smile, frown, pout, wink) that induce wrinkles. The neutral and expression images are processed to simulate wrinkle aging by registering the wrinkles that are visible in the expression image onto the neutral image, thereby generating a wrinkle-aged simulated image. Advantageously, a person's own wrinkle histological data is utilized, hence providing an accurate and realistic wrinkle aging simulation. Similarly, the neutral image is processed to eliminate all visible wrinkles thereby generating a wrinkle de-aged simulation image. Additionally, blending of a neutral image with an aged or de-aged simulation image is disclosed, where the degree of blending is based on statistical modeling of skin condition with age and/or expected outcome of a particular type of treatment. The methods and systems disclosed have wide applicability, including, for example, areas such as dermatology, cosmetics and computer animation, among others.
    • 披露方法和系统来实际模拟使用中性状态(自然外观)图像和诱发皱纹的一个或多个表情图像(例如,微笑,皱眉,ut ut,眨眼)的人的面部皱纹老化。 处理中性和表达图像以通过将表情图像中可见的皱纹记录到中性图像上来模拟皱纹老化,从而产生皱纹老化的模拟图像。 有利地,利用人自己的皱纹组织学数据,从而提供准确和逼真的皱纹老化模拟。 类似地,中性图像被处理以消除所有可见的皱纹,从而产生皱纹去老化的模拟图像。 此外,公开了中性图像与老化或老化模拟图像的混合,其中混合度基于皮肤状况与特定类型治疗的年龄和/或预期结果的统计学模型。 所公开的方法和系统具有广泛的适用性,包括例如皮肤病学,化妆品和计算机动画等领域。
    • 9. 发明申请
    • AUTOMATIC MASK DESIGN AND REGISTRATION AND FEATURE DETECTION FOR COMPUTER-AIDED SKIN ANALYSIS
    • 计算机辅助皮肤分析自动设计与注册及特征检测
    • WO2010082942A9
    • 2011-01-20
    • PCT/US2009032630
    • 2009-01-30
    • CANFIELD SCIENT INCDEMIRLI RAMAZANGADDIPATI DEEPAK
    • DEMIRLI RAMAZANGADDIPATI DEEPAK
    • G06K9/00
    • G06K9/00281A61B5/441G06K9/00234G06K9/6206
    • Methods and systems for automatically generating a mask delineating a region of interest (ROI) within an image containing skin are disclosed. The image may be of an anatomical area containing skin, such as the face, neck, chest, shoulders, arms or hands, among others, or may be of portions of such areas, such as the cheek, forehead, or nose, among others. The mask that is generated is based on the locations of anatomical features or landmarks in the image, such as the eyes, nose, eyebrows and lips, which can vary from subject to subject and image to image. As such, masks can be adapted to individual subjects and to different images of the same subjects, while delineating anatomically standardized ROIs, thereby facilitating standardized, reproducible skin analysis over multiple subjects and/or over multiple images of each subject. Moreover, the masks can be limited to skin regions that include uniformly illuminated portions of skin while excluding skin regions in shadow or hot-spot areas that would otherwise provide erroneous feature analysis results. Methods and systems are also disclosed for automatically registering a skin mask delineating a skin ROI in a first image captured in one imaging modality (e.g., standard white light, UV light, polarized light, multi-spectral absorption or fluorescence imaging, etc.) onto a second image of the ROI captured in the same or another imaging modality. Such registration can be done using linear as well as non-linear spatial transformation techniques.
    • 公开了用于自动生成描绘包含皮肤的图像内的感兴趣区域(ROI)的掩模的方法和系统。 该图像可以是包含皮肤的解剖区域,例如面部,颈部,胸部,肩部,手臂或手等,或者可以是诸如脸颊,额头或鼻子等部分的区域 。 生成的面具是基于图像中的解剖特征或地标的位置,例如眼睛,鼻子,眉毛和嘴唇,其可以从主体到主体和图像到图像而变化。 因此,在描绘解剖学标准化的ROI的同时,掩模可以适应于个体主体和相同主体的不同图像,从而促进在多个对象上和/或多个图像上的标准化,可再现的皮肤分析。 此外,面罩可以限于包括皮肤均匀照射部分的皮肤区域,同时排除阴影或热点区域中的皮肤区域,否则会提供错误的特征分析结果。 还公开了用于自动登记在一种成像模式(例如,标准白光,紫外光,偏振光,多光谱吸收或荧光成像等)捕获的第一图像中描绘皮肤ROI的皮肤掩模的方法和系统, 在相同或另一成像模式中捕获的ROI的第二图像。 这种注册可以使用线性和非线性空间变换技术来完成。