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1. 发明申请

WO2004039993A1 POLYNUCLEOTIDE ENCODING A PYRANOSONE DEHYDRATASE 审中-公开
标题翻译：多核苷酸编码吡咯烷酮脱氢酶
公开(公告)号：WO2004039993A1
公开(公告)日：2004-05-13
申请号：PCT/GB2003/004594
申请日：2003-10-24
申请人： DANISCO A/S , YU, Shukun , HANSEN, Egon, Bech , PEDERSEN, Hans, Christian , TURNER, Mark , WEIERGANG, Inge
发明人： YU, Shukun , HANSEN, Egon, Bech , PEDERSEN, Hans, Christian , TURNER, Mark , WEIERGANG, Inge
IPC分类号： C12P17/06
CPC分类号： C07H3/08 , A01N43/16 , C12N9/88 , C12P17/06 , A01N2300/00
摘要： The present invention relates to a polynucleotide sequence encoding a pyranosone dehydratase. The present invention further relates to a method for producing transgenic plants which are resistant to pathogens, particularly fungal pathogens, comprising transforming the plants or part thereof with at least a polynucleotide sequence encoding a pyranosone dehydratase. Further aspects relate to transgenic plants comprising at least a heterologous polynucleotide sequence encoding pyranosone dehydratase, which plants are resistant to pathogens, particularly fungal pathogens. The present invention further relates to the in situ production of one or more antimicrobial compounds, such as microthecin, cortalcerone and/or ascopyrone P (APP) in a host organism, such as a plant.
摘要翻译：本发明涉及编码吡喃龙素脱水酶的多核苷酸序列。本发明还涉及一种用于产生对病原体特别是真菌病原体具有抗性的转基因植物的方法，包括用至少一种编码吡喃松香脱水酶的多核苷酸序列转化植物或其部分。另外的方面涉及至少包含编码吡喃松香脱水酶的异源多核苷酸序列的转基因植物，该植物对病原体特别是真菌病原体具有抗性。本发明还涉及一种或多种抗微生物化合物如主要生物体如植物中的微阵列，皮质酮和/或异黄酮P（APP）的原位生产。

2. 发明申请

WO2004039820A1 MATERIAL 审中-公开
标题翻译：材料
公开(公告)号：WO2004039820A1
公开(公告)日：2004-05-13
申请号：PCT/GB2003/004603
申请日：2003-10-24
申请人： DANISCO A/S , YU, Shukun , BUCHTER-LARSEN, Aksel , MORGAN, Andrew , TURNER, Mark , PEDERSEN, Hans, Christian , WEIERGANG, Inge , BECH-HANSEN, Egon
发明人： YU, Shukun , BUCHTER-LARSEN, Aksel , MORGAN, Andrew , TURNER, Mark , PEDERSEN, Hans, Christian , WEIERGANG, Inge , BECH-HANSEN, Egon
IPC分类号： C07H3/08
CPC分类号： C07H3/08 , A01N43/16 , A01N25/22 , A01N2300/00
摘要： The present invention provides an antimicrobial material comprising (i) an antimicrobial compound in a stabilised form (a "stabilised compound"), or (ii) (a) a first conversion agent capable of converting a precursor of an antimicrobial compound (a "primary precursor") to the antimicrobial compound; and (b) (I) a primary precursor, or (II) a second conversion agent capable of converting a precursor of the primary antimicrobial precursor (a "secondary precursor") to the primary precursor; and a secondary precursor; wherein the antimicrobial compound is selected from microthecin and derivatives thereof, such as compounds having Formula (I), wherein R 1 and R 2 are independently selected from H and C(=O)R 3 wherein R 3 is a hydrocarbyl group, and R 4 is from H and OH.
摘要翻译：本发明提供一种抗微生物材料，其包含（i）稳定化形式的抗微生物化合物（“稳定化合物”），或（ii）（a）能够转化抗微生物化合物前体的第一转化剂前体“）; 和（b）（I）初级前体，或（II）能够将初级抗微生物前体（“次级前体”）的前体转化成初级前体的第二转化剂; 和二级前体; 其中所述抗微生物化合物选自微喜岩石及其衍生物，例如具有式（I）的化合物，其中R 1和R 2独立地选自H和C（= O）R 3，其中R 3是烃基，R 4是H，哦。

3. 发明申请

WO2003037918A2 SEQUENCES 审中-公开
标题翻译：序列
公开(公告)号：WO2003037918A2
公开(公告)日：2003-05-08
申请号：PCT/GB2002/004916
申请日：2002-10-30
申请人： DANISCO A/S , MORGAN, Andrew, John , YU, Shukun , WEIERGANG, Inge , PEDERSEN, Hans, Christian
发明人： MORGAN, Andrew, John , YU, Shukun , WEIERGANG, Inge , PEDERSEN, Hans, Christian
IPC分类号： C07K14/00
CPC分类号： C12P17/06 , C12N9/88
摘要： The present invention discloses sequence information relating to pyranosone dehydratase. The invention further relates to the use of pyranosone dehydratase in the conversion of AF to APP and microthecin and the conversion of glucosone to cortalcerone.
摘要翻译：本发明公开了与吡喃酮脱水酶有关的序列信息。本发明还涉及吡喃酮脱水酶在将AF转化为APP和微喜岩石以及将葡萄糖转化为皮质醇时的用途。

4. 发明申请

WO2004083226A1 ANTIMICROBIAL FORMULATION COMPRISING MICROTHECIN OR DERIVATIVES THEREOF AND THEIR USES IN PREVENTION AND THERAPY 审中-公开
标题翻译：包含微血管密度或其衍生物的抗微生物制剂及其在预防和治疗中的应用
公开(公告)号：WO2004083226A1
公开(公告)日：2004-09-30
申请号：PCT/GB2004/001148
申请日：2004-03-18
申请人： DANISCO A/S , MORGAN, Andrew, John , TURNER, Mark , YU, Shukun , WEIERGAN, Inge , PEDERSEN, Hans, Christian
发明人： MORGAN, Andrew, John , TURNER, Mark , YU, Shukun , WEIERGAN, Inge , PEDERSEN, Hans, Christian
IPC分类号： C07H3/08
CPC分类号： A01N43/16 , A01N63/00 , C07H3/08 , C12N9/88 , C12Q1/18
摘要： The present invention provides an anti-microbial composition comprising microthecin or a derivative thereof as an active anti-microbial component, and the microorganism is selected from Candida albicans, Aspergillus fumigentus, E. coli, Staphylococcus aureus, Eimeria spp., Cryptosporidium parvum, Cryptosporidium aruem and Plasmodium spp
摘要翻译：本发明提供了一种抗微生物组合物，其包含作为活性抗微生物成分的微喜岩石或其衍生物，微生物选自白色念珠菌，烟曲霉，大肠杆菌，金黄色葡萄球菌，艾美球虫，隐孢子虫，隐孢子虫 aruem和疟原虫

5. 发明申请

WO2011077342A1 METHOD 审中-公开
标题翻译：方法
公开(公告)号：WO2011077342A1
公开(公告)日：2011-06-30
申请号：PCT/IB2010/055912
申请日：2010-12-17
申请人： DANISCO A/S , YU, Shukun
发明人： YU, Shukun
IPC分类号： C12Q1/37 , C12Q1/44 , C12Q1/68 , G01N33/49 , G01N33/569 , G01N33/574
CPC分类号： C12Q1/37 , C12Q1/42 , C12Q1/68 , G01N33/491 , G01N33/56966 , G01N33/57484
摘要： A method of detecting a phytase activity or a protease activity is described. The method comprises the steps of: (a) providing a composition comprising a phytate/protein complex in a liquid or a gel; wherein the phytate/protein complex provides a detectable property to the composition; (b) providing a sample that comprises or is suspected of comprising phytase activity and/or protease activity, wherein the phytase and/or protease activity is capable of causing a change in the detectable property of the composition; (c) contacting the composition with the sample; and (d) determining if there is a detectable change in detectable property of the composition.
摘要翻译：描述了检测植酸酶活性或蛋白酶活性的方法。该方法包括以下步骤：（a）在液体或凝胶中提供包含植酸盐/蛋白质复合物的组合物; 其中植酸盐/蛋白质复合物为组合物提供可检测的性质; （b）提供包含或怀疑含有植酸酶活性和/或蛋白酶活性的样品，其中所述植酸酶和/或蛋白酶活性能够引起组合物的可检测性质的变化; （c）使组合物与样品接触; 和（d）确定组合物的可检测性质是否存在可检测的变化。

6. 发明申请

WO2012032472A2 ADDITIVE 审中-公开
标题翻译：添加剂
公开(公告)号：WO2012032472A2
公开(公告)日：2012-03-15
申请号：PCT/IB2011/053901
申请日：2011-09-06
申请人： DANISCO A/S , YU, Shukun , POULSEN, Charlotte Horsmans , DALSGAARD, Søren , WANG, Huaming , NIKOLAEV, Igor
发明人： YU, Shukun , POULSEN, Charlotte Horsmans , DALSGAARD, Søren , WANG, Huaming , NIKOLAEV, Igor
IPC分类号： A23L1/015
CPC分类号： A23L1/034 , A23K10/10 , A23K20/189 , A23L5/25 , A23L29/06 , C12N9/80 , C12Y305/01004
摘要： The present invention relates to amidase enzymes and a feed or food additive comprising the amidase enzyme capable of degrading ochratoxin.
摘要翻译：本发明涉及酰胺酶和包含能够降解赭曲霉毒素的酰胺酶的饲料或食品添加剂。

7. 发明申请

WO2003038107A3 PROCESS FOR THE PRODUCTION OF ASCOPYRONE P 审中-公开
公开(公告)号：WO2003038107A3
公开(公告)日：2003-05-08
申请号：PCT/GB2002/004895
申请日：2002-10-30
申请人： DANISCO A/S , MORGAN, Andrew, John , YU, Shukun
发明人： MORGAN, Andrew, John , YU, Shukun
IPC分类号： C12P17/06
摘要： The present invention relates to a process for preparing ascopyrone P, or a derivative thereof, said process comprising the steps of: (I) converting a starch-type substrate to 1.5-anhydro-D-fructose with α-1,4-glucan lyase at a pH of from about 3.8 to 7.0; (II) treating said 1,5-anhydro-D-fructose with 1,5-anhydro-D-fructose dehydratase and/or pyranosone dehydratase and optionally ascopyrone P synthase at a pH of from about 5.0 to about 7.5.

8. 发明申请

WO2003038107A2 PROCESS 审中-公开
标题翻译：处理
公开(公告)号：WO2003038107A2
公开(公告)日：2003-05-08
申请号：PCT/GB2002/004895
申请日：2002-10-30
申请人： DANISCO A/S , MORGAN, Andrew, John , YU, Shukun
发明人： MORGAN, Andrew, John , YU, Shukun
IPC分类号： C12P17/06
CPC分类号： C12P17/06 , C12N9/88
摘要： The present invention relates to a process for preparing ascopyrone P, or a derivative thereof, said process comprising the steps of: (I) converting a starch-type substrate to 1.5-anhydro-D-fructose with α-1,4-glucan lyase at a pH of from about 3.8 to 7.0; (II) treating said 1,5-anhydro-D-fructose with 1,5-anhydro-D-fructose dehydratase and/or pyranosone dehydratase and optionally ascopyrone P synthase at a pH of from about 5.0 to about 7.5.
摘要翻译：本发明涉及一种制备异黄酮酮P或其衍生物的方法，所述方法包括以下步骤：（I）用α-1,4-葡聚糖裂解酶将淀粉型底物转化为1.5-脱水-D-果糖在约3.8至7.0的pH下; （II）在约5.0至约7.5的pH下用1,5-脱水-D-果糖脱水酶和/或吡喃糖酮脱水酶和任选的代谢物P合酶处理所述1,5-脱水-D-果糖。

9. 发明申请

WO2003038084A1 ASCOPYRONE P SYNTHASE 审中-公开
公开(公告)号：WO2003038084A1
公开(公告)日：2003-05-08
申请号：PCT/GB2002/004885
申请日：2002-10-30
申请人： DANISCO A/S , MORGAN, Andrew, John , REFDAHL, Charlotte , YU, Shukun
发明人： MORGAN, Andrew, John , REFDAHL, Charlotte , YU, Shukun
IPC分类号： C12N9/88
CPC分类号： C12N9/90 , C12P7/26 , C12P17/06
摘要： The present invention relates to the purification and characterisation of ascopyrone P synthase.
摘要翻译：本发明涉及异黄酮酮合成酶的纯化和表征。

10. 发明申请

WO2009133464A3 OXIDATION PROCESS 审中-公开
公开(公告)号：WO2009133464A3
公开(公告)日：2009-11-05
申请号：PCT/IB2009/005738
申请日：2009-04-30
申请人： DANISCO A/S , MIKKELSEN, Jørn, Dalgaard , KRAGH, Karsten, Mathias , MIKKELSEN, Rene , DERKX, Patrick, Maria, Franciscus , YU, Shukun , MULDER, Harm , NIKOLAEV, Igor
发明人： MIKKELSEN, Jørn, Dalgaard , KRAGH, Karsten, Mathias , MIKKELSEN, Rene , DERKX, Patrick, Maria, Franciscus , YU, Shukun , MULDER, Harm , NIKOLAEV, Igor
IPC分类号： C12N9/04 , C12P19/04
摘要： A method of oxidising a saccharide, by contacting the saccharide with an alcohol dehydrogenase (ADH) enzyme selected from a quinone redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide (NAD+) redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide phosphate (NADP+) redox cofactor-dependent ADH, and any combination thereof is described. An oxidised saccharide obtainable by the method and products, in particular food products and paper products, containing the oxidised saccharide, are also described.

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