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1. 发明授权

US06913579B2 Electrosurgical working end and method for obtaining tissue samples for biopsy 有权
标题翻译：电外科手术和获取组织样本进行活检的方法
公开(公告)号：US06913579B2
公开(公告)日：2005-07-05
申请号：US10136874
申请日：2002-04-30
申请人： Csaba Truckai , Rodney Perkins , John H. Shadduck
发明人： Csaba Truckai , Rodney Perkins , John H. Shadduck
IPC分类号： A61B17/00 , A61B18/14 , A61B10/00 , A61B18/18
CPC分类号： A61B18/1442 , A61B18/1815 , A61B2017/00084 , A61B2017/2933 , A61B2017/2934 , A61B2017/2945 , A61B2018/00619 , A61B2018/00702 , A61B2018/00791 , A61B2018/1432
摘要： An electrosurgical working end and method for obtaining a tissue sample for biopsy purposes, for example, from a patient's lung or a liver. The working end provides curved jaw members that are positioned on opposing sides of the targeted anatomic structure. The working end carries a slidable extension member that is laterally flexible with inner surfaced that slide over the jaw members to clamp tissue therebetween. As the extension member advances, the jaws compress the tissue just ahead of the advancing extension member to allow the laterally-outward portion of the extension member to ramp over the tissue while a cutting element contemporaneously cuts the tissue. By this means, the transected tissue margin is captured under high compression. The working end carries a bi-polar electrode arrangement that engages the just-transected medial tissue layers as well as surface layers to provides Rf current flow for tissue welding purposes that is described as a medial-to-surface bi-polar approach.
摘要翻译：一种电外科手术工作端和用于获得例如来自患者的肺或肝的活组织检查目的的组织样本的方法。工作端提供弯曲的夹爪构件，其定位在目标解剖结构的相对侧上。工作端承载可滑动的延伸构件，其具有内表面的侧向柔性，其在钳口构件上滑动以在其间夹紧组织。当延伸构件前进时，钳口在前进的延伸构件正前方压缩组织，以允许延伸构件的横向向外部分在组织上斜坡，同时切割元件同时切割组织。通过这种方式，在高压缩下捕获横切的组织边缘。工作端携带双极电极装置，其接合刚刚横切的内侧组织层以及表面层，以提供用于组织焊接目的的Rf电流，其被描述为内向 - 双向极性方法。

2. 发明授权

US10058336B2 System for use in treatment of vertebral fractures 有权
$System for use in treatment of vertebral fractures$
公开(公告)号：US10058336B2
公开(公告)日：2018-08-28
申请号：US13083411
申请日：2011-04-08
申请人： Csaba Truckai , Aaron Germain , John H. Shadduck
发明人： Csaba Truckai , Aaron Germain , John H. Shadduck
IPC分类号： A61B17/16 , A61M29/00 , A61B17/34 , A61B17/88 , A61B90/00
CPC分类号： A61B17/1671 , A61B17/1604 , A61B17/1626 , A61B17/1631 , A61B17/1633 , A61B17/1642 , A61B17/1657 , A61B17/3421 , A61B17/3472 , A61B17/8805 , A61B17/8855 , A61B17/8858 , A61B2090/031
摘要： Methods and devices that displace bone or other hard tissue to create a cavity in the tissue. Where such methods and devices rely on a driving mechanism for providing moving of the device to form a profile that improves displacement of the tissue. These methods and devices also allow for creating a path or cavity in bone for insertion of bone cement or other filler to treat a fracture or other condition in the bone. The features relating to the methods and devices described herein can be applied in any region of bone or hard tissue where the tissue or bone is displaced to define a bore or cavity instead of being extracted from the body such as during a drilling or ablation procedure.

3. 发明授权

US08562607B2 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US08562607B2
公开(公告)日：2013-10-22
申请号：US11282316
申请日：2005-11-19
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/00
CPC分类号： A61B17/1631 , A61B17/1615 , A61B17/1617 , A61B17/1642 , A61B17/1671 , A61B2017/00557 , A61B2217/005 , A61B2217/007 , A61M1/0082
摘要： The invention provides instruments and methods for prophylactic treatment of an osteoporotic vertebral body or for treating a vertebral compression fracture (VCF). In one exemplary method, a probe system uses a high speed rotational cutter for abrading or cutting a plane within vertebral cancellous bone. Optional irrigation and aspiration sources are included in the probe system for removing abraded bone debris. In one embodiment, the high speed cutter uses a tissue-selective abrading surface that abrades or cuts bone but does not cut soft tissue. After the creation of a weakened cut plane in the bone, reduction of the fracture requires reduced forces.
摘要翻译：本发明提供了用于预防性治疗骨质疏松性椎体或用于治疗椎体压缩性骨折（VCF）的仪器和方法。在一个示例性方法中，探针系统使用高速旋转切割器来研磨或切割椎骨松质骨内的平面。用于清除磨损的骨碎片的探头系统中包括可选的灌注和抽吸源。在一个实施例中，高速切割机使用磨损或切割骨头但不切割软组织的组织选择性研磨表面。在骨骼中形成削弱的切割平面之后，骨折的减少需要减小的力量。

4. 发明申请

US20130172870A1 TISSUE CUTTING SYSTEMS AND METHODS 有权
标题翻译：组织切割系统和方法
公开(公告)号：US20130172870A1
公开(公告)日：2013-07-04
申请号：US13540396
申请日：2012-07-02
申请人： Aaron Germain , John H. Shadduck , Michael D. Walker , Kyle Klein , Csaba Truckai
发明人： Aaron Germain , John H. Shadduck , Michael D. Walker , Kyle Klein , Csaba Truckai
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B1/012 , A61B1/303 , A61B17/32002 , A61B18/08 , A61B18/1482 , A61B2017/320028 , A61B2017/4216 , A61B2018/00196 , A61B2018/00589 , A61B2018/00601 , A61B2018/1475 , A61B2218/002 , A61B2218/007
摘要： A probe for resecting and coagulating tissue comprises an outer sleeve having a tissue cutting window and an inner sleeve having a tissue cutting distal end. And RF cutting region is formed at the distal end of the inner member and an RF coagulation region is formed on an exterior surface of the inner member immediately proximal to the cutting surface. A single power supply providing a single RF energy mode can be connected to both RF applicator regions to simultaneously cut and coagulate tissue.
摘要翻译：用于切割和凝固组织的探针包括具有组织切割窗口的外套筒和具有组织切割远端的内套筒。并且RF切割区域形成在内部构件的远端处，并且RF紧固区域形成在紧邻切割表面的内部构件的外表面上。提供单个RF能量模式的单个电源可以连接到RF施加器区域以同时切割和凝固组织。

5. 发明申请

US20120330292A1 TISSUE EXTRACTION DEVICES AND METHODS 有权
标题翻译：组织提取装置和方法
公开(公告)号：US20120330292A1
公开(公告)日：2012-12-27
申请号：US13277913
申请日：2011-10-20
申请人： John H. Shadduck , Aaron Germain , Kyle Klein , Michael D. Walker , Csaba Truckai
发明人： John H. Shadduck , Aaron Germain , Kyle Klein , Michael D. Walker , Csaba Truckai
IPC分类号： A61B17/3205 , A61B18/14 , A61B18/08 , A61B18/18 , A61B18/20
CPC分类号： A61B18/1482 , A61B1/015 , A61B1/05 , A61B17/32002 , A61B17/3205 , A61B18/00 , A61B18/1206 , A61B18/18 , A61B2017/320028 , A61B2018/00196 , A61B2018/00202 , A61B2018/00559 , A61B2018/00589 , A61B2018/00601 , A61B2018/00625 , A61B2018/048 , A61B2018/126 , A61B2018/1437 , A61B2218/002 , A61B2218/007
摘要： Tissue may be cut and extracted from an interior location in a patient's body using a probe or tool which both effects cutting and causes vaporization of a liquid or other fluid to propel the cut tissue through an extraction lumen of the cutting device. The cutting may be achieved using an electrosurgical electrode assembly, including a first electrode on a cutting member and a second electrode within a cutting probe or tool. Thus, over a first cutting portion, radio frequency current may help cut the tissue and over a second or over transition region, the RF current may initiate vaporization of the fluid or other liquid to propel the tissue from the cutting device.
摘要翻译：可以使用探针或工具从患者体内的内部位置切割并提取组织，所述探针或工具都会影响切割并引起液体或其它流体的蒸发，以将切割的组织推动通过切割装置的提取腔。可以使用电外科电极组件来实现切割，所述电外科电极组件包括切割构件上的第一电极和切割探针或工具内的第二电极。因此，在第一切割部分上，射频电流可以帮助切割组织并且在第二或过渡过渡区域上，RF电流可以引发流体或其它液体的蒸发，以推动来自切割装置的组织。

6. 发明申请

US20120132214A1 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：US20120132214A1
公开(公告)日：2012-05-31
申请号：US13308449
申请日：2011-11-30
申请人： Edward M. Gillis , John H. Shadduck , Csaba Truckai
发明人： Edward M. Gillis , John H. Shadduck , Csaba Truckai
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： An implant for treating an obstructive airway disorder includes an elongate implant body configured for implanting in airway-interface tissue. The implant body has a medial portion extending between first and second anchoring end portions. The medial portion of the implant body is axially compliant and the end portions are axially non-compliant. Methods of treating an airway disorder comprising implanting an axially-extending implant in an airway-interface tissue are also provided.
摘要翻译：用于治疗阻塞性气道障碍的植入物包括构造成用于植入气道界面组织中的细长植入体。植入体具有在第一和第二锚固端部之间延伸的中间部分。植入物主体的中间部分是轴向柔性的，并且端部轴向不顺应。还提供了治疗气道障碍的方法，包括在气道 - 界面组织中植入轴向延伸的植入物。

7. 发明申请

US20120059381A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20120059381A1
公开(公告)日：2012-03-08
申请号：US13282653
申请日：2011-10-27
申请人： John H. Shadduck , Csaba Truckai
发明人： John H. Shadduck , Csaba Truckai
IPC分类号： A61B17/58
CPC分类号： A61B17/7098
摘要： Methods and instruments for treating an osteoporotic vertebral body or for treating a vertebral compression fracture. An exemplary method includes introducing an open knit structure together with a bone cement into a bone wherein the knit structure extends substantially throughout the interior of the cement volume. In one aspect of the invention, the bone cement volumes cures with the filament structure reinforcing the cement. In another aspect of the invention, the open knit structure is configured to direct flows of bone cement to apply forces for reducing a vertebral compression fracture. In another aspect of the invention, the system provides bone cement flows that extend through the knit structure thus allowing the cement to fully interdigitate with the cancellous bone.
摘要翻译：用于治疗骨质疏松性椎体或用于治疗椎体压缩性骨折的方法和手段。一种示例性的方法包括将开放的针织结构与骨水泥一起引入到骨中，其中针织结构基本上在水泥体积的整个内部延伸。在本发明的一个方面，骨水泥体积固化，细丝结构增强了水泥。在本发明的另一方面，开放针织结构被配置为引导骨粘固剂的流动以施加用于减少椎骨压缩性骨折的力。在本发明的另一方面，该系统提供延伸穿过针织结构的骨水泥流，从而允许水泥与松质骨完全交叉指向。

8. 发明授权

US08070753B2 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US08070753B2
公开(公告)日：2011-12-06
申请号：US11196045
申请日：2005-08-02
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/7095 , A61B17/7098 , A61B17/864 , A61B17/8811 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.
摘要翻译：本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。示例性系统利用Rf能量组合导电骨填充材料，用于聚合流入羽流的表面以控制填充材料的几何形状以及由填充材料的流入引起的力的施加。在另一个实施方案中，治疗骨的方法包括将一定体积的填充材料注入骨中，并选择性地改变骨填充物的选定部分的粘度以控制填充材料在骨内的流动方向。使用这种方法治疗骨骼的系统包括用于将填充材料输送到骨骼中的导引器，以及选择性地与填充材料耦合的能量源，以改变填充材料流出导引器时的粘度。

9. 发明申请

US20110276045A1 ELECTROSURGICAL INSTRUMENT AND METHOD OF USE 审中-公开
标题翻译：静电仪器及其使用方法
公开(公告)号：US20110276045A1
公开(公告)日：2011-11-10
申请号：US13101182
申请日：2011-05-05
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B18/08 , A61B17/28 , A61B18/18
CPC分类号： A61B18/1442
摘要： A particular embodiment of the invention provides an electrosurgical working end for performing high strength welding of tissue comprising a body having a tissue contacting energy delivery surface. The body includes pixel portions and non-pixel portions distributed within the tissue contacting surface. The pixel portions comprise a positive temperature coefficient of resistance (PTCR) material with at least one pixel portion configured to switch Rf current on and off in the at least one pixel portion responsive to tissue temperature adjacent the at least one pixel portion. The pixel portions can be configured to be coupled to an Rf current source such as an Rf generator. The pixelated energy delivery surfaces are capable of highly localized modulation of Rf energy application to the engaged tissue to create high strength tissue welds.
摘要翻译：本发明的一个具体实施方案提供了一种电外科工作端，用于对组织进行高强度焊接，包括具有组织接触能量输送表面的主体。主体包括分布在组织接触表面内的像素部分和非像素部分。像素部分包括正温度系数电阻（PTCR）材料，其中至少一个像素部分被配置成响应于与至少一个像素部分相邻的组织温度在至少一个像素部分中开启和关闭Rf电流。像素部分可以被配置为耦合到诸如Rf发生器的Rf电流源。像素化的能量传递表面能够对接合的组织进行Rf能量的高度局部调节，以产生高强度组织焊接。

10. 发明申请

US20100174286A1 BONE TREATMENT SYSTEMS AND METHODS FOR INTRODUCING AN ABRADING STRUCTURE TO ABRADE BONE 有权
标题翻译：用于引导骨质疏松结构的骨治疗系统和方法
公开(公告)号：US20100174286A1
公开(公告)日：2010-07-08
申请号：US12729004
申请日：2010-03-22
申请人： Csaba Truckai , John H. Shadduck
发明人： Csaba Truckai , John H. Shadduck
IPC分类号： A61B17/00
CPC分类号： A61B17/32002 , A61B17/1615 , A61B17/1617 , A61B17/1631 , A61B17/1642 , A61B17/1668 , A61B17/1671 , A61B17/320725 , A61B2017/00261 , A61B2017/00557 , A61B2017/320004 , A61B2217/005 , A61B2217/007 , A61M1/0082
摘要： The invention provides instruments and methods for prophylactic treatment of an osteoporotic vertebral body or for treating a vertebral compression fracture (VCF). In one exemplary method, a probe system uses a high speed rotational elastomeric cutter having an optional expandable abrasive surface for abrading or cutting at least one path or region within vertebral cancellous bone. Irrigation and aspiration sources are included in the probe system for removing abraded bone debris. In one embodiment, the high speed rotational abrader uses a tissue-selective abrading surface that abrades or cuts bone but does not cut soft tissue. In another embodiment, an expandable abrading surface allows the treatment of bone with low pressures to create paths or spaces without explosive expansion forces known in prior art balloon procedures that are designed to crush and compact cancellous bone in a vertebra. After the creation of a path or space, an in-situ hardenable bone cement volume is introduced into each path or space to support the vertebra.
摘要翻译：本发明提供了用于预防性治疗骨质疏松性椎体或用于治疗椎体压缩性骨折（VCF）的仪器和方法。在一个示例性方法中，探针系统使用具有可选的可扩展研磨表面的高速旋转弹性体切割器，用于研磨或切割椎骨松质骨内的至少一个路径或区域。用于清除磨损的骨碎片的探针系统中包含灌溉和吸入源。在一个实施例中，高速旋转磨擦机使用磨损或切割骨骼而不切割软组织的组织选择性研磨表面。在另一个实施方案中，可膨胀研磨表面允许用低压处理骨骼以产生路径或空间，而不会在现有技术的球囊过程中已知的爆炸膨胀力被设计成压缩和压紧椎骨中的松质骨。在创建路径或空间之后，将原位可硬化的骨水泥体积引入到每个路径或空间中以支撑椎骨。

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