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1. 发明授权

US09161798B2 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US09161798B2
公开(公告)日：2015-10-20
申请号：US12728127
申请日：2010-03-19
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00 , A61B17/88 , A61B17/00 , A61B19/00
CPC分类号： A61B17/8836 , A61B17/8822 , A61B90/98 , A61B2017/00084
摘要： Systems and methods for treating vertebral compression fractures are provided. A kit can include at least one body containing a bone cement precursor to be mixed with at least one other bone cement precursor to form a bone cement. The body or a package containing the body can include at least one sensor. In some embodiments the sensor can be a temperature sensor. In some methods, data from the sensor can be used to determine certain parameters related to a treatment interval involving the bone cement.
摘要翻译：提供了治疗椎体压缩性骨折的系统和方法。试剂盒可以包括至少一个含有待与至少一种其他骨水泥前体混合以形成骨粘固剂的骨水泥前体的主体。身体或包含身体的包装可以包括至少一个传感器。在一些实施例中，传感器可以是温度传感器。在一些方法中，可以使用来自传感器的数据来确定与涉及骨水泥的治疗间隔相关的某些参数。

2. 发明授权

US08487021B2 Bone treatment systems and methods 有权
公开(公告)号：US08487021B2
公开(公告)日：2013-07-16
申请号：US12395532
申请日：2009-02-27
申请人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
发明人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
IPC分类号： C08K9/12 , A61F2/28 , A61L24/06
CPC分类号： A61L24/0094 , A61B17/7095 , A61B17/8822 , A61B17/8833 , A61B17/8836 , A61B2017/00022 , A61K31/78 , A61L24/001 , A61L24/0084 , A61L24/0089 , A61L24/06 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

3. 发明申请

US20090292290A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20090292290A1
公开(公告)日：2009-11-26
申请号：US12427531
申请日：2009-04-21
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8805 , A61B17/7095 , A61B17/8822 , A61B17/8827
摘要： Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation.
摘要翻译：用于治疗脊椎压缩性骨折的系统，骨水泥和方法可以利用包含可混合液体单体组分和包括聚合物颗粒在内的非液体组分的骨粘固剂，其中非液体组分构造成用于通过液体单体控制暴露于液体单体骨水泥的设定间隔。在使用方法中，将液体和非液体组分混合，并将骨粘固剂注入到骨中，其中提供了延长的凝固间隔，其中混合物配置为防止不想要的外渗的流动性。

4. 发明申请

US20100249793A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20100249793A1
公开(公告)日：2010-09-30
申请号：US12728127
申请日：2010-03-19
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8836 , A61B17/8822 , A61B90/98 , A61B2017/00084
摘要： Systems and methods for treating vertebral compression fractures are provided. A kit can include at least one body containing a bone cement precursor to be mixed with at least one other bone cement precursor to form a bone cement. The body or a package containing the body can include at least one sensor. In some embodiments the sensor can be a temperature sensor. In some methods, data from the sensor can be used to determine certain parameters related to a treatment interval involving the bone cement.
摘要翻译：提供了治疗椎体压缩性骨折的系统和方法。试剂盒可以包括至少一个含有待与至少一种其他骨水泥前体混合以形成骨粘固剂的骨水泥前体的主体。身体或包含身体的包装可以包括至少一个传感器。在一些实施例中，传感器可以是温度传感器。在一些方法中，可以使用来自传感器的数据来确定与涉及骨水泥的治疗间隔相关的某些参数。

5. 发明申请

US20100016467A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20100016467A1
公开(公告)日：2010-01-21
申请号：US12395527
申请日：2009-02-27
申请人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
发明人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
IPC分类号： C08L33/12
CPC分类号： A61L24/06 , A61B17/8805 , A61B17/8822 , A61B17/8833 , A61B2017/00022 , A61L24/0084 , A61L24/02 , A61L24/043 , A61L27/16 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
摘要翻译：本公开内容涉及具有用于椎体成形术程序和其它骨成形术程序的延长工作时间的骨水泥制剂以及水泥注射器，其包括用于按需控制水泥粘度和流动参数的能量输送系统。骨水泥制剂可以包括具有至少一种单体和包含聚合物颗粒和过氧化苯甲酰（BPO））的非液体组分的液体组分。非液体组分可以进一步构造成允许BPO受控地暴露于液体单体，以便能够控制骨水泥组合物的粘度。

6. 发明授权

US08562620B2 Bone treatment systems 有权
标题翻译：骨治疗系统
公开(公告)号：US08562620B2
公开(公告)日：2013-10-22
申请号：US12427531
申请日：2009-04-21
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8805 , A61B17/7095 , A61B17/8822 , A61B17/8827
摘要： Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation.
摘要翻译：用于治疗脊椎压缩性骨折的系统，骨水泥和方法可以利用包含可混合液体单体组分和包括聚合物颗粒在内的非液体组分的骨粘固剂，其中非液体组分构造成用于通过液体单体控制暴露于液体单体骨水泥的设定间隔。在使用方法中，将液体和非液体组分混合，并将骨粘固剂注入到骨中，其中提供了延长的凝固间隔，其中混合物配置为防止不想要的外渗的流动性。

7. 发明申请

US20090247664A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20090247664A1
公开(公告)日：2009-10-01
申请号：US12395532
申请日：2009-02-27
申请人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
发明人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
IPC分类号： A61L24/04 , A61K6/08
CPC分类号： A61L24/0094 , A61B17/7095 , A61B17/8822 , A61B17/8833 , A61B17/8836 , A61B2017/00022 , A61K31/78 , A61L24/001 , A61L24/0084 , A61L24/0089 , A61L24/06 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
摘要翻译：本公开内容涉及具有用于椎体成形术程序和其它骨成形术程序的延长工作时间的骨水泥制剂以及水泥注射器，其包括用于按需控制水泥粘度和流动参数的能量输送系统。骨水泥制剂可以包括具有至少一种单体和包含聚合物颗粒和过氧化苯甲酰（BPO））的非液体组分的液体组分。非液体组分可以进一步构造成允许BPO受控地暴露于液体单体，以便能够控制骨水泥组合物的粘度。

8. 发明授权

US09445854B2 Bone treatment systems and methods 有权
公开(公告)号：US09445854B2
公开(公告)日：2016-09-20
申请号：US12395527
申请日：2009-02-27
申请人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
发明人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
IPC分类号： A61L24/06 , A61B17/88 , A61L24/00 , A61L24/02 , A61L27/16 , A61L27/46 , A61L27/50 , A61L24/04 , A61B17/00
CPC分类号： A61L24/06 , A61B17/8805 , A61B17/8822 , A61B17/8833 , A61B2017/00022 , A61L24/0084 , A61L24/02 , A61L24/043 , A61L27/16 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

9. 发明申请

US20110004208A1 ELECTROSURGICAL INSTRUMENT WITH REPLACEABLE CARTRIDGE 审中-公开
标题翻译：具有可更换墨盒的电磁仪
公开(公告)号：US20110004208A1
公开(公告)日：2011-01-06
申请号：US12605742
申请日：2009-10-26
申请人： Csaba Truckai , John Shadduck , James Baker
发明人： Csaba Truckai , John Shadduck , James Baker
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B17/32 , A61B2017/2945 , A61B2018/00619 , A61B2018/00755 , A61B2018/00791 , A61B2018/00875 , A61B2018/1432 , A61B2018/1495
摘要： Various embodiments provide an electrosurgical instrument with a disposable electrosurgical cartridge. In one embodiment, the cartridge has first and second energy-delivery surfaces that carry first and second opposing polarity conductors coupled to a voltage source, together with first and second temperature-responsive variable impedance bodies exposed partly in the respective-delivery surfaces. The cartridge further carries a slidable blade member. The temperature-responsive variable impedance bodies are coupled to the voltage source by series and parallel circuitry. In use, the variable impedance bodies are adapted to modulate current flow and ohmic heating in engaged tissue by providing controlled current paths in the tissue and through the variable impedance bodies as the temperature-responsive bodies sense the temperature of adjacent engaged tissue. The engagement surfaces are capable of highly localized modulation of Rf energy application to engaged tissue to provide high and low temperatures, voltage and current in the tissue to create high strength welds.
摘要翻译：各种实施例提供具有一次性电外科手术盒的电外科器械。在一个实施例中，盒具有第一和第二能量传递表面，其承载耦合到电压源的第一和第二相对极性导体以及部分地暴露在相应输送表面中的第一和第二温度响应可变阻抗体。该盒还带有可滑动的刀片部件。温度响应可变阻抗体通过串联和并联电路耦合到电压源。在使用中，可变阻抗体适于通过在温度响应体感测相邻接合组织的温度时通过在组织中和通过可变阻抗体中提供受控的电流路径来调制接合组织中的电流和欧姆加热。接合表面能够对接合组织进行Rf能量的高度局部调节，以在组织中提供高和低温度，电压和电流以产生高强度焊缝。

10. 发明申请

US20080086196A1 POLYMER MATRIX DEVICES FOR TREATMENT OF VASCULAR MALFORMATIONS 审中-公开
标题翻译：用于治疗血管畸形的聚合物基质装置
公开(公告)号：US20080086196A1
公开(公告)日：2008-04-10
申请号：US11953809
申请日：2007-12-10
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61B17/12181 , A61B2017/12068 , A61F2/07 , A61F2/848 , A61F2220/0016
摘要： A system for treating a wide-neck aneurysm comprising a mesh-like sleeve fabricated from a class of polymer filaments that carry conductive particles therein to provide the filaments with a specified resistivity. The releasable mesh-like sleeve is introduced to the site of a targeted vascular malformation by the working end of a catheter that carries an electrode arrangement at its distal terminus. The system further provides an electrical source and controller (i) that modulates power delivery to the polymer matrix which can then fuse the sleeve to the wall of a blood vessel to span across the vascular malformation.
摘要翻译：一种用于治疗宽颈动脉瘤的系统，包括由一类聚合物长丝制成的网状套筒，所述聚合物细丝在其中携带导电颗粒以提供具有指定电阻率的细丝。可释放的网状套筒通过导管的工作端引导到目标血管畸形部位，该导管在其远端具有电极装置。该系统还提供一种电源和控制器（i），其调节向聚合物基质的功率传递，然后可将该套管熔合到血管的壁以横跨血管畸形。

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