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1. 发明申请

US20130149732A1 METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES 有权
标题翻译：标记含有硫酸的蛋白质和肽的方法
公开(公告)号：US20130149732A1
公开(公告)日：2013-06-13
申请号：US13594040
申请日：2012-08-24
申请人： Cristina M. Furdui , Allen W. Tsang , Jiang Qian
发明人： Cristina M. Furdui , Allen W. Tsang , Jiang Qian
IPC分类号： G01N1/30
CPC分类号： G01N33/58 , C07C69/738 , C07K1/1077 , C07K1/13 , G01N1/30 , G01N33/64 , Y10T436/18
摘要： A method of labeling a sulfenic acid (—SOH) group of a cysteine residue in a protein; or peptide, comprises contacting said protein or peptide with a beta-ketoester to covalently couple said beta-ketoester to said cysteine residue and form a beta-ketoester-labeled cysteine residue in said protein or peptide.
摘要翻译：标记蛋白质中半胱氨酸残基的亚磺酸（-SOH）基团的方法; 或肽包括使所述蛋白质或肽与β-酮酯接触以将所述β-酮酯共价连接到所述半胱氨酸残基并在所述蛋白质或肽中形成β-酮酯标记的半胱氨酸残基。

2. 发明授权

US09023653B2 Method of labeling sulfenic acid-containing proteins and peptides 有权
标题翻译：标记含亚磺酸蛋白质和肽的方法
公开(公告)号：US09023653B2
公开(公告)日：2015-05-05
申请号：US13594040
申请日：2012-08-24
申请人： Cristina M. Furdui , Allen W. Tsang , Jiang Qian
发明人： Cristina M. Furdui , Allen W. Tsang , Jiang Qian
IPC分类号： G01N33/58 , G01N1/30 , G01N33/64 , C07K1/13 , C07K1/107
CPC分类号： G01N33/58 , C07C69/738 , C07K1/1077 , C07K1/13 , G01N1/30 , G01N33/64 , Y10T436/18
摘要： A method of labeling a sulfenic acid (—SOH) group of a cysteine residue in a protein; or peptide, comprises contacting said protein or peptide with a beta-ketoester to covalently couple said beta-ketoester to said cysteine residue and form a beta-ketoester-labeled cysteine residue in said protein or peptide.
摘要翻译：标记蛋白质中半胱氨酸残基的亚磺酸（-SOH）基团的方法; 或肽包括使所述蛋白质或肽与β-酮酯接触以将所述β-酮酯共价连接到所述半胱氨酸残基并在所述蛋白质或肽中形成β-酮酯标记的半胱氨酸残基。

3. 发明授权

US09194824B1 Anvils and ultra-high pressure apparatuses using the same 有权
标题翻译：砧座和使用其的超高压装置
公开(公告)号：US09194824B1
公开(公告)日：2015-11-24
申请号：US13425647
申请日：2012-03-21
申请人： Jiang Qian , Kenneth E. Bertagnolli
发明人： Jiang Qian , Kenneth E. Bertagnolli
IPC分类号： G01N23/20 , G01N21/03
CPC分类号： G01N21/0317 , G01N23/20041
摘要： Polycrystalline diamond (“PCD”) anvils and associated ultra-high pressure apparatuses employing such anvils. The PCD anvils include an anvil body defining an anvil face. The anvil body comprises a plurality of diamond grains defining a plurality of interstitial regions, with a metal-solvent catalyst occupying at least a portion of the plurality of interstitial regions. The plurality and diamond grains and the metal-solvent catalyst of the PCD collectively exhibit a coercivity of about 115 Oe or more and a specific magnetic saturation of about 15 G·cm3/g or less.
摘要翻译：多晶金刚石（“PCD”）砧座和使用这种砧座的相关超高压装置。 PCD砧包括定义砧面的砧体。砧体包括限定多个间隙区域的多个金刚石晶粒，其中金属溶剂催化剂占据多个间隙区域的至少一部分。 PCD的多个金刚石晶粒和金属 - 溶剂催化剂共同表现出约115Oe以上的矫顽力和约15G·cm 3 / g以下的比磁饱和。

4. 发明授权

US09094230B1 Network transfer protocol 有权
标题翻译：网络传输协议
公开(公告)号：US09094230B1
公开(公告)日：2015-07-28
申请号：US12901121
申请日：2010-10-08
申请人： Jiang Qian
发明人： Jiang Qian
IPC分类号： H04L12/28 , H04L12/40 , H04L29/06
CPC分类号： H04L45/74 , H04L1/1607 , H04L1/1874 , H04L1/188 , H04L12/40071 , H04L29/0604 , H04L29/06102 , H04L29/0653 , H04L29/1249 , H04L47/10 , H04L47/193 , H04L47/27 , H04L61/256 , H04L63/029 , H04L67/06 , H04L69/03 , H04L69/16 , H04L69/161 , H04L69/164 , H04L69/22
摘要： Systems, methods and computer program products facilitate communication on a network by transmitting a communication on the network from a first node to a second node, the communication including a first segment and a second segment. The first segment consists essentially of a destination port and a data length of the communication, and the second segment includes a payload and at least one of a connection ID, a sequence number, and an opcode. A responsive communication is then received from the second node, the responsive communication acknowledging receipt of the communication transmitted from the first node.
摘要翻译：系统，方法和计算机程序产品通过在网络上从第一节点传输到第二节点的通信来促进网络上的通信，该通信包括第一段和第二段。第一段基本上由通信的目的地端口和数据长度组成，第二段包括有效负载以及连接ID，序列号和操作码中的至少一个。然后从第二节点接收响应通信，响应通信确认从第一节点发送的通信的接收。

5. 发明申请

US20130169638A1 METHOD AND SYSTEM FOR GENERATING A MULTI-DIMENSIONAL SURFACE MODEL OF A GEOMETRIC STRUCTURE 有权
标题翻译：用于产生几何结构的多维表面模型的方法和系统
公开(公告)号：US20130169638A1
公开(公告)日：2013-07-04
申请号：US13338381
申请日：2011-12-28
申请人： Carlos Carbonera , Vasily Vylkov , Daniel R. Starks , Jiang Qian , Eric J. Voth
发明人： Carlos Carbonera , Vasily Vylkov , Daniel R. Starks , Jiang Qian , Eric J. Voth
IPC分类号： G06T15/00
CPC分类号： G06T17/10 , G06T11/60 , G06T15/08 , G06T17/00 , G06T2210/12
摘要： A method of constructing a bounding box comprises: acquiring a set of sensed data points; adding, for each sensed data point, at least one calculated data point; and defining a bounding box containing the sensed and calculated data points. A method of identifying voxels in a voxel grid corresponding to a plurality of data points comprises: calculating, for each data point, a distance between it and each voxel; creating a subset of voxels comprising voxels having a distance from one data point that is less than a predetermined distance; creating another subset comprising those voxels that neighbor a voxel in the first subset; computing, for each voxel in the second subset, a distance between it and each voxel in the first subset; and identifying each voxel in the first subset that is a distance away from each voxel in the second subset that exceeds a predetermined distance.
摘要翻译：一种构造边界框的方法包括：获取一组感测数据点; 对于每个感测数据点，添加至少一个计算的数据点; 并定义包含感测和计算的数据点的边界框。一种识别对应于多个数据点的体素网格中的体元的方法包括：针对每个数据点计算其与每个体素之间的距离; 创建体素的子集，其包括距离一个数据点的距离小于预定距离的体素; 创建另一子集，其包括邻近所述第一子集中的体素的所述体素; 对于第二子集中的每个体素计算其与第一子集中的每个体素之间的距离; 以及识别所述第一子集中距离所述第二子集中超过预定距离的每个体素的距离的每个体素。

6. 发明授权

US08473276B2 Universal language input 有权
标题翻译：通用语言输入
公开(公告)号：US08473276B2
公开(公告)日：2013-06-25
申请号：US12033697
申请日：2008-02-19
申请人： Jiang Qian , Lei Zhang
发明人： Jiang Qian , Lei Zhang
IPC分类号： G10L15/18
CPC分类号： G06F17/289 , G06F17/30669
摘要： Systems, methods, and apparatuses including computer program products for universal language input are provided. In one implementation, a method is provided. The method includes using a first application or operating system component to detect user input to an application interface of a second application. The method also includes, as input is detected in the application interface, automatically using the first application to provide one or more translations of the input including, sending the input to a translation model, receiving translated input from the translation model, and sending the translated input to the application interface of the second application.
摘要翻译：提供了包括用于通用语言输入的计算机程序产品的系统，方法和装置。在一个实现中，提供了一种方法。该方法包括使用第一应用或操作系统组件来检测对第二应用的应用接口的用户输入。该方法还包括当在应用程序界面中检测到输入时，自动使用第一应用程序提供输入的一个或多个翻译，包括将输入发送到翻译模型，从翻译模型接收翻译输入，并发送翻译的输入到第二个应用程序的应用程序界面。

7. 发明申请

US20080206576A1 Superabrasive compact including diamond-silicon carbide composite, methods of fabrication thereof, and applications therefor 有权
标题翻译：超级磨料包括金刚石 - 碳化硅复合材料，其制造方法及其应用
公开(公告)号：US20080206576A1
公开(公告)日：2008-08-28
申请号：US12001990
申请日：2007-12-12
申请人： Jiang Qian , Kenneth E. Bertagnolli , Michael A. Vail , Jason Wiggins , Jim I. Dewberry , David P. Miess
发明人： Jiang Qian , Kenneth E. Bertagnolli , Michael A. Vail , Jason Wiggins , Jim I. Dewberry , David P. Miess
IPC分类号： B32B5/00
CPC分类号： B24D3/10 , B24D18/00 , B82Y30/00 , C04B35/52 , C04B35/6261 , C04B35/62802 , C04B35/6316 , C04B35/645 , C04B2235/3826 , C04B2235/383 , C04B2235/3834 , C04B2235/427 , C04B2235/428 , C04B2235/5436 , C04B2235/5445 , C04B2235/5454 , C04B2235/5472 , C04B2235/781 , C04B2235/785 , C04B2235/786 , C04B2235/80 , C04B2235/96 , C04B2235/9607 , F16C17/02 , F16C17/04 , F16C33/043 , F16C33/26 , F16C2206/04 , F16C2220/20 , F16C2240/48 , F16C2352/00 , Y10T428/252 , Y10T428/30
摘要： Embodiments of the present invention relate to diamond-silicon carbide composites, superabrasive compacts including such diamond-silicon carbide composites, and methods of fabricating such diamond-silicon carbide composites and superabrasive compacts. In one embodiment, a superabrasive compact includes a substrate and a superabrasive table bonded to the substrate. The superabrasive table comprises diamond-silicon carbide composite including a matrix comprising nanometer-sized silicon carbide grains and micrometer-sized diamond grains dispersed through the matrix. In another embodiment, a method of fabricating a superabrasive compact is disclosed. An assembly comprising a mixture including diamond particles and silicon is formed. The silicon comprises amorphous silicon, crystalline silicon crystallized from amorphous silicon formed by a milling process, or combinations thereof. A substrate is positioned in proximity to the mixture. The assembly is subjected to heat and pressure to form a superabrasive compact comprising a superabrasive table bonded to the substrate. The superabrasive table comprises diamond-silicon carbide composite including diamond grains dispersed through a matrix of silicon carbide grains.
摘要翻译：本发明的实施方案涉及金刚石 - 碳化硅复合材料，包括这种金刚石 - 碳化硅复合材料的超级磨料压块，以及制造这种金刚石 - 碳化硅复合材料和超级磨料压块的方法。在一个实施例中，超级磨料致密体包括基底和结合到基底的超研磨台。超级磨料台包括金刚石 - 碳化硅复合材料，其包括通过基体分散的纳米级碳化硅晶粒和微米级金刚石颗粒的基体。在另一个实施例中，公开了一种制造超硬磨料的方法。形成包含金刚石颗粒和硅的混合物的组件。硅包括非晶硅，通过研磨方法形成的非晶硅结晶的结晶硅或其组合。衬底位于该混合物附近。将组件经受热和压力以形成包含结合到衬底的超级磨料工作台的超硬磨料。超级磨料台包括金刚石 - 碳化硅复合材料，其包括通过碳化硅颗粒的基体分散的金刚石颗粒。

8. 发明授权

US08429204B2 Short point-of-interest title generation 有权
标题翻译：短期利益标题产生
公开(公告)号：US08429204B2
公开(公告)日：2013-04-23
申请号：US13549340
申请日：2012-07-13
申请人： Jiang Qian , Vincent Zhou , Bo Zheng , Yu Zheng
发明人： Jiang Qian , Vincent Zhou , Bo Zheng , Yu Zheng
IPC分类号： G06F17/30 , G06F17/28
CPC分类号： G06F17/2745
摘要： Short POI titles are generated by removing unnecessary administrative area prefixes from existing POI titles and replacing necessary administrative area prefixes with shorter aliases. Administrative area prefixes are identified and analyzed to determine whether they are necessary. The analysis includes determining (1) whether the remainders with the prefixes excluded include a common suffix as a prefix, and (2) whether the remainders are unique in an applicable metropolis area. If a remainder does not include as a prefix a common suffix and is unique in the applicable metropolis area, the corresponding prefix is determined unnecessary and removed from the existing POI title to generate a short POI title. Otherwise, the corresponding prefix is determined necessary and replaced with a shorter alias to generate a short POI title.
摘要翻译：通过从现有POI标题中删除不必要的管理区域前缀，并用较短的别名替换必要的管理区域前缀来生成简短的POI标题。对行政区域前缀进行识别和分析，以确定它们是否必要。分析包括确定（1）排除前缀的余数是否包括作为前缀的公共后缀，以及（2）在适用的大都会区域中剩余部分是否是唯一的。如果余数不包括作为前缀的公共后缀，并且在适用的大都市区域中是唯一的，则相应的前缀被确定为不必要的并且从现有POI标题中移除以生成短的POI标题。否则，相应的前缀被确定为必需，并用较短的别名替换以生成短的POI标题。

9. 发明申请

US20130043078A1 POLYCRYSTALLINE DIAMOND COMPACT INCLUDING A CARBONATE-CATALYZED POLYCRYSTALLINE DIAMOND TABLE AND APPLICATIONS THEREFOR 有权
标题翻译：多晶金刚石，包括碳酸钙催化的多晶金刚石表及其应用
公开(公告)号：US20130043078A1
公开(公告)日：2013-02-21
申请号：US13552052
申请日：2012-07-18
申请人： Jiang Qian , C. Eugene McMurray , Debkumar Mukhopadhyay , Jason K. Wiggins , Michael A. Vail , Kenneth E. Bertagnolli
发明人： Jiang Qian , C. Eugene McMurray , Debkumar Mukhopadhyay , Jason K. Wiggins , Michael A. Vail , Kenneth E. Bertagnolli
IPC分类号： B24D3/06 , B23B51/00 , E21B10/46 , B24D18/00
CPC分类号： B24D3/10 , B22F7/062 , B22F2005/001 , B24D18/0009 , C22C26/00 , E21B10/54 , E21B10/56 , E21B10/567 , F16C33/043 , F16C33/108 , F16C2352/00 , Y10T408/89
摘要： In an embodiment, a polycrystalline diamond compact includes a substrate and a preformed polycrystalline diamond table bonded to the substrate. The table includes bonded diamond grains defining interstitial regions. The table includes an upper surface, a back surface bonded to the substrate, and at least one lateral surface extending therebetween. The table includes a first region extending inwardly from the upper surface and the lateral surface. The first region exhibits a first interstitial region concentration and includes at least one interstitial constituent disposed therein, which may be present in at least a residual amount and includes at least one metal carbonate and/or at least one metal oxide. The table includes a second bonding region adjacent to the substrate that extends inwardly from the back surface. The second bonding region exhibits a second interstitial region concentration that is greater than the first interstitial region concentration and includes a metallic infiltrant therein.
摘要翻译：在一个实施例中，多晶金刚石致密体包括基底和结合到基底的预成型多晶金刚石台。该表包括定义间隙区域的结合金刚石颗粒。桌子包括上表面，粘合到基底的后表面和在它们之间延伸的至少一个侧表面。桌子包括从上表面和侧表面向内延伸的第一区域。第一区域表现出第一间隙区域浓度并且包括至少一个置于其中的间隙成分，其可以以至少残留量存在并且包括至少一种金属碳酸盐和/或至少一种金属氧化物。桌子包括与衬底相邻的第二接合区域，其从后表面向内延伸。第二结合区域表现出比第一间隙区域浓度大的第二间隙区域浓度，并且其中包括金属渗透剂。

10. 发明授权

US08361429B2 Polycrystalline diamond materials and related products 失效
标题翻译：多晶金刚石材料及相关产品
公开(公告)号：US08361429B2
公开(公告)日：2013-01-29
申请号：US13245249
申请日：2011-09-26
申请人： Michael A. Vail , Kenneth E. Bertagnolli , Jason Wiggins , Jiang Qian , David P. Miess
发明人： Michael A. Vail , Kenneth E. Bertagnolli , Jason Wiggins , Jiang Qian , David P. Miess
IPC分类号： B01J3/06 , E21B10/36 , B24D3/02 , C09C1/68 , B29C67/00
CPC分类号： E21B10/46 , B01J3/062 , B01J2203/062 , B01J2203/0655 , B01J2203/0685
摘要： Embodiments relate to methods of fabricating PCD materials by subjecting a mixture that exhibits a broad diamond particle size distribution to an HPHT process, PCD materials so-formed, and PDCs including a polycrystalline diamond table comprising such PCD materials. In an embodiment, a PCD material includes a plurality of bonded diamond grains that exhibit a substantially unimodal diamond grain size distribution characterized, at least in part, by a parameter θ that is less than about 1.0. θ = x 6 · σ , where x is the average grain size of the substantially unimodal diamond grain size distribution, and σ is the standard deviation of the substantially unimodal diamond grain size distribution.
摘要翻译：实施方案涉及通过使表现出宽金刚石粒度分布的混合物经受HPHT方法，所形成的PCD材料和包括包含这种PCD材料的多晶金刚石台的PDC来制造PCD材料的方法。在一个实施方案中，PCD材料包括多个结合的金刚石晶粒，其表现出基本上单峰金刚石晶粒尺寸分布，其至少部分地由参数和特征表征; 小于约1.0。＆thetas; = x 6·＆sgr ，其中x是基本上单峰金刚石晶粒尺寸分布的平均晶粒尺寸，是基本上单峰金刚石晶粒尺寸分布的标准偏差。

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