专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06453531B1 Automotive window assembly tool 有权
标题翻译：汽车窗组装工具
公开(公告)号：US06453531B1
公开(公告)日：2002-09-24
申请号：US09657988
申请日：2000-09-08
申请人： Craig R. Krass , Roger A. Johnson , Lisa Fugate , Craig A. Johnson , James C. Shur
发明人： Craig R. Krass , Roger A. Johnson , Lisa Fugate , Craig A. Johnson , James C. Shur
IPC分类号： B23P1904
CPC分类号： B25B5/163 , B25B7/02 , B25B7/123 , B62D65/06 , Y10T29/5363 , Y10T29/539
摘要： An assembly tool for setting a lateral position of a rear window panel placed on a window glass support surface of a rear window opening of an automotive vehicle is provided. The tool includes an upper jaw for extending over a C pillar of the automotive vehicle, the upper jaw has a weather strip channel contact member and an adjustable length extending finger with an extreme edge window contacting surface for setting a lateral position of the rear window panel within the window glass support surfaces. A lower jaw pivotally is connected with the upper jaw for contacting and gripping an inboard surface of the vehicle C pillar. A quick connect vice mechanism for closing the upper jaw and the lower jaw toward one another to grip the C pillar is also included.
摘要翻译：提供了一种用于设置放置在机动车辆的后窗开口的窗玻璃支撑表面上的后窗玻璃板的横向位置的组装工具。该工具包括用于在机动车辆的C柱上延伸的上钳口，上钳口具有耐候条通道接触构件和可调节长度延伸的手指，其具有极端边缘窗接触表面，用于设置后窗板的横向位置在窗玻璃支撑面内。下颚枢转地与上颚连接，用于接触和夹紧车辆C柱的内侧表面。还包括用于将上钳口和下钳口彼此闭合以夹紧C柱的快速连接副机构。

2. 发明授权

US5795756A Method and compounds for the inhibition of adenylyl cyclase 失效
公开(公告)号：US5795756A
公开(公告)日：1998-08-18
申请号：US762833
申请日：1996-12-10
申请人： Roger A. Johnson , Laurent Desaubry , Ilana Shoshani
发明人： Roger A. Johnson , Laurent Desaubry , Ilana Shoshani
IPC分类号： C07H19/16 , C07H19/20 , C12Q1/527 , C12N9/00
CPC分类号： C07H19/16 , C07H19/20 , C12Q1/527
摘要： The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.

3. 发明授权

US07045309B2 9-substituted adenine derivatives as prodrug regulators of cell and tissue function 失效
标题翻译： 9-取代的腺嘌呤衍生物作为细胞和组织功能的前体调节剂
公开(公告)号：US07045309B2
公开(公告)日：2006-05-16
申请号：US10332314
申请日：2001-07-06
申请人： Roger A. Johnson , Praveen Pande , Wolfgang Laux , Gilles Gosselin
发明人： Roger A. Johnson , Praveen Pande , Wolfgang Laux , Gilles Gosselin
IPC分类号： G01N33/53 , C07H19/20
CPC分类号： C07H19/20
摘要： The present invention relates to 9-substituted adenine derivatives represented by formula (I) wherein W is selected from the group consisting of H, halogen, azido and amino group; X is selected from the group consisting of O, S, N(H), CH2, CH and C; Y is selected from the group consisting of H, hydroxy, C1-4 alkyl, C1-4 alkoxy and halogen; R is selected from the group consisting of H, hydroxymethyl, C1-4 alkyl, and C1-4 alkoxy; R1is selected from the group consisting of O, NH and CH2; R2represents a radical selected from the group consisting of —(CH2)n—S—C(O)—R4 and —(CH2)n—S—S—R4, where n=1-4 and R4is a C1-4-alkyl or aryl group and R4 is optionally substituted with a halogen, amino, N-alkylamino, N, N-dialkylamino or C1-4 alkoxy group and wherein each of the R2radicals may be the same or different; and R3is O or S. The derivatives are useful as prodrugs for inhibiting adenylyl cyclase and lowering 3′:5′-cAMP in cells, thereby inhibiting adenylyl cyclase dependent effects within cells.
摘要翻译：本发明涉及由式（I）表示的9-取代腺嘌呤衍生物，其中W选自H，卤素，叠氮基和氨基; X选自O，S，N（H），CH 2，CH和C; Y选自H，羟基，C 1-4烷基，C 1-4烷氧基和卤素; R选自H，羟甲基，C 1-4烷基和C 1-4烷氧基; R 1选自O，NH和CH 2; R 2表示选自以下的基团： - （CH 2）n --SC（O）-R 4 其中n = 1-4和R 4 和 - （CH 2）2 - >是C 1-4烷基或芳基，R 4任选被卤素，氨基，N-烷基氨基，N，N-二烷基氨基或C 其中每个R 2个基团可以相同或不同; R 3为O或S.该衍生物可用作抑制腺苷酸环化酶和降低细胞中3'：5-cAMP的前药，从而抑制细胞内腺苷酸环化酶依赖性作用。

4. 发明授权

US6012883A Hybrid lay-up tool 失效
公开(公告)号：US6012883A
公开(公告)日：2000-01-11
申请号：US72716
申请日：1998-05-05
申请人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
发明人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
IPC分类号： B23Q3/08 , B29C33/38 , B29C70/34 , B29C70/44 , B29C70/54 , B23C1/30
CPC分类号： B29C43/3642 , B23Q3/086 , B29C33/3842 , B29C43/12 , B29C70/342 , B29C70/44 , B29C70/545 , B29C2043/3644 , B29K2105/0854 , Y10T29/532 , Y10T409/303808 , Y10T409/30868 , Y10T409/309016
摘要： A hybrid tool serves as a form on which constituent materials are applied for bonding or curing into a part in a desired configuration. It also serves as a holder for the bonded or cured materials in the originally applied position during subsequent machining. The hybrid tool is made by fabricating a face sheet of composite material having a facing surface configured to the reverse of a desired shape of one surface of a part to be made on the tool. The actual part will be laid up on the facing surface, cured while on the tool, and even trimmed before release. Base structure of the tool holds the facing surface of the face sheet in the desired shape, and includes ground-engaging pads that define an "A" datum plane. The tool aligns a reference plane of the face sheet parallel to the datum plane. A substantially continuous groove in the face sheet, used for trimming the part, opens in the facing surface. Edge trimming of the part on the tool is performed using a CNC machine tool following a part program to move a cutter extending into the groove to engage the full thickness of the part. The groove corresponds in space to the position represented by the cutter path of travel in the part program because of the accurate spatial relationship of the face sheet reference plane and the datum plane. One embodiment of the invention includes filling the groove in the facing surface with a foaming, self-skinning sacrificial material and covering the facing surface of the tool with a caul sheet. The tool is heated to cure the foaming material, which fills the groove and forms a hard, smooth surface skin, flush with the facing surface of the tool to support the part during lay up. A series of skin plies are laid-up to form a tool-side skin, and other components of the part are laid-up on the tool-side skin. A vacuum bag is sealed to peripheral regions of the facing surface of the tool around the laid-up skin and components. An adhesive/resin matrix in the skin and components is bonded/cured in the conventional manner within the vacuum bag to produce a rigid integral assembly. The vacuum bag is removed, uncovering the rigid integral assembly for trimming. A cutter of a machine tool is guided on a predetermined path around the facing surface of the tool, running in the foam-filled groove below the facing surface of the tool and cutting a peripheral edge around the rigid integral assembly. After trimming, the rigid integral assembly is removed from the facing surface of the tool.

5. 发明授权

US4644594A Patient transport device 失效
标题翻译：患者运输装置
公开(公告)号：US4644594A
公开(公告)日：1987-02-24
申请号：US726430
申请日：1985-04-24
申请人： Roger A. Johnson
发明人： Roger A. Johnson
IPC分类号： A61G1/003 , A61G7/10 , A61G1/02
CPC分类号： A61G7/1019 , A61G1/003 , A61G7/103 , A61G7/1034 , A61G7/1046 , A61G2200/32 , A61G2200/34 , A61G2210/50
摘要： A patient transport device which is characterized in one embodiment by a flat rail bed having spaced, parallel, upturned rails on opposite sides, with a seat slidably disposed over the rails by means of rollers rotating in the rails on spaced axles carried by the seat. The device is designed to transport patients from one side of a bed to the other, as well as to and from wheelchairs and dollys. In another embodiment, the seat is enlarged to define a body support, the body support and rail bed combination is supported by hydraulic cylinders to facilitate height adjustment and the larger patient transport device is used to transport patients to and from x-ray tables, dollys, hospital beds and the like.
摘要翻译：一种患者运输装置，其特征在于一个实施例中，平板轨道床在相对侧上具有间隔开的平行的向上翻转的轨道，其中可滑动地设置在轨道上的座位通过在由座椅承载的间隔开的轴上的导轨中旋转的滚子。该设备旨在将患者从床的一侧运送到另一侧，以及往返于轮椅和小车。在另一个实施例中，座椅被扩大以限定身体支撑，身体支撑和轨道床组合由液压缸支撑以便于高度调节，并且较大的患者运输装置用于将患者运送到和从X射线台，小车，医院病床等。

6. 发明授权

US06759002B1 Method for making a composite 失效
标题翻译：制作复合材料的方法
公开(公告)号：US06759002B1
公开(公告)日：2004-07-06
申请号：US09407278
申请日：1999-09-29
申请人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
发明人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
IPC分类号： B29C7044
CPC分类号： B29C43/12 , B23Q3/086 , B29C33/3842 , B29C43/3642 , B29C70/342 , B29C70/44 , B29C70/545 , B29C2043/3644 , B29K2105/0854 , Y10T156/1057
摘要： A method of manufacturing a composite uses a hybrid tool which serves both as a form on which constituent materials are applied for bonding or curing into a part in a desired configuration, and as a fixture for holding the bonded or cured materials in the originally applied position during subsequent machining of a peripheral edge of the part. The method includes fabricating a face sheet of composite material having a facing surface configured to the reverse of a desired shape of one surface of a part to be made on the tool. The materials for the part are applied on the face sheet, debulked, bonded or cured, and edge trimmed thereon, all while on the face sheet in the originally applied position.
摘要翻译：复合材料的制造方法使用混合式工具，其既用作构成材料的结构，也可以将其固化成期望结构的部件，并且作为用于将结合或固化的材料保持在原始施加位置的固定装置在后续加工零件的外围边缘时。该方法包括制造具有面对表面的复合材料的面片，该面对构造成与要在工具上制成的部件的一个表面的期望形状相反。用于零件的材料应用在面板上，减粘，粘合或固化，并在其上修剪边缘，同时在原始施加位置的面板上。

7. 发明授权

US6132957A Method and compounds for the inhibition of adenylyl cyclase 失效
标题翻译：用于抑制腺苷酸环化酶的方法和化合物
公开(公告)号：US6132957A
公开(公告)日：2000-10-17
申请号：US71779
申请日：1998-05-04
申请人： Roger A. Johnson , Laurent Desaubry , Ilana Shoshani
发明人： Roger A. Johnson , Laurent Desaubry , Ilana Shoshani
IPC分类号： C07H19/16 , C07H19/20 , C12Q1/527 , C12N9/00 , C07D473/00
CPC分类号： C07H19/16 , C07H19/20 , C12Q1/527
摘要： The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.
摘要翻译：本发明揭示了一系列腺苷和腺苷的衍生物和类似物，即抑制腺苷酸环化酶活性的3'-腺苷衍生物。这些新合成的化合物包括已知的腺苷酸环化酶最有效的抑制剂。本发明还公开了一种测定腺苷酸环化酶活性抑制的方法。

8. 发明授权

US4804889A Electrode feedthrough assembly for arc discharge lamp 失效
标题翻译：电弧放电灯用电极馈通组件
公开(公告)号：US4804889A
公开(公告)日：1989-02-14
申请号：US135406
申请日：1987-12-18
申请人： David A. Reid , Roger A. Johnson , John Gutta
发明人： David A. Reid , Roger A. Johnson , John Gutta
IPC分类号： H01J9/32 , H01J61/36
CPC分类号： H01J61/366 , H01J9/323
摘要： A ceramic arc tube assembly for an arc discharge lamp includes an arc tube having openings for electrode feedthroughs at opposite ends. The feedthroughs each comprise a niobium tube having a tungsten electrode welded to it. A connection wire is welded to the feedthrough at or near the end of the niobium tube, and the feedthrough is subsequently sealed into the arc tube with the connection wire abutting the arc tube. Since the connection wire is prewelded to the feedthrough, the feedthrough can be made as short as practicable without risk of damaging the seal during welding. As a result, feedthrough material cost is substantially reduced. Preferably, the connection wire is used for locating the feedthrough in the arc tube during seal formation.
摘要翻译：一种用于电弧放电灯的陶瓷电弧管组件包括在相对端具有用于电极馈通的开口的电弧管。馈通每个包括具有焊接到其上的钨电极的铌管。连接线焊接到铌管端部或其附近的馈通端，随后连接线与电弧管邻接，随后将馈通密封到电弧管中。由于连接线预焊接到馈通，所以馈通可以尽可能短地实现，而不会在焊接期间损坏密封的风险。因此，馈通材料成本显着降低。优选地，连接线用于在密封形成期间将馈通定位在电弧管中。

9. 发明授权

US4197404A Preparation of .gamma.-quinacridone pigment 失效
标题翻译： γ-喹吖啶酮颜料的制备
公开(公告)号：US4197404A
公开(公告)日：1980-04-08
申请号：US903948
申请日：1978-05-08
申请人： Roger A. Johnson
发明人： Roger A. Johnson
IPC分类号： C09B48/00 , C09B67/52
CPC分类号： C09B48/00
摘要： In a process for preparing pigmentary .gamma.-quinacridone by oxidizing .beta.-dihydroquinacridone with a mild alkali-stable oxidizing agent in a liquid medium consisting of alkali metal hydroxide, water and a polar, alkali-stable, water-soluble organic liquid, this invention provides for an improvement wherein the oxidation is conducted in the presence of 0.1% to 1% by weight of an o-carboxybenzamidomethyl quinacridone compound whereby the resulting .gamma.-quinacridone exhibits sufficiently high strength so that milling or solvent treatments to increase pigment strength are unnecessary.
摘要翻译：在由碱金属氢氧化物，水和极性，碱稳定的水溶性有机液体组成的液体介质中，用温和的碱稳定氧化剂氧化β-二氢喹吖啶酮的方法中，本发明提供为了改善其中氧化在0.1％-1％（重量）的邻羧基苯甲酰胺甲基喹吖啶酮化合物的存在下进行，由此得到的γ-喹吖啶酮表现出足够高的强度，从而不需要研磨或溶剂处理来提高颜料强度。

10. 发明授权

US06168358A Hybrid lay-up tool 有权
公开(公告)号：US06168358A
公开(公告)日：2001-01-02
申请号：US09408295
申请日：1999-09-29
申请人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
发明人： Dwight L. Engwall , Chris J. Morrow , Kevin J. Steen , Roger A. Johnson
IPC分类号： B23C300
CPC分类号： B29C43/3642 , B23Q3/086 , B29C33/3842 , B29C43/12 , B29C70/342 , B29C70/44 , B29C70/545 , B29C2043/3644 , B29K2105/0854 , Y10T29/532 , Y10T409/303808 , Y10T409/30868 , Y10T409/309016
摘要： A hybrid tool serves as a form on which constituent materials are applied for bonding or curing into a part in a desired configuration. It also serves as a holder for the bonded or cured materials in the originally applied position during subsequent machining. The hybrid tool is made by fabricating a face sheet of composite material having a facing surface configured to the reverse of a desired shape of one surface of a part to be made on the tool. The actual part will be laid up on the facing surface, cured while on the tool, and even trimmed before release. Base structure of the tool holds the facing surface of the face sheet in the desired shape, and includes ground-engaging pads that define an “A” datum plane. The tool aligns a reference plane of the face sheet parallel to the datum plane. A substantially continuous groove in the face sheet, used for trimming the part, opens in the facing surface. Edge trimming of the part on the tool is performed using a CNC machine tool following a part program to move a cutter extending into the groove to engage the full thickness of the part. The groove corresponds in space to the position represented by the cutter path of travel in the part program because of the accurate spatial relationship of the face sheet reference plane and the datum plane. One embodiment of the invention includes filling the groove in the facing surface with a foaming, self-skinning sacrificial material and covering the facing surface of the tool with a caul sheet. The tool is heated to cure the foaming material, which fills the groove and forms a hard, smooth surface skin, flush with the facing surface of the tool to support the part during lay up. A series of skin plies are laid-up to form a tool-side skin, and other components of the part are laid-up on the tool-side skin. A vacuum bag is sealed to peripheral regions of the facing surface of the tool around the laid-up skin and components. An adhesive/resin matrix in the skin and components is bonded/cured in the conventional manner within the vacuum bag to produce a rigid integral assembly. The vacuum bag is removed, uncovering the rigid integral assembly for trimming. A cutter of a machine tool is guided on a predetermined path around the facing surface of the tool, running in the foam-filled groove below the facing surface of the tool and cutting a peripheral edge around the rigid integral assembly. After trimming, the rigid integral assembly is removed from the facing surface of the tool.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式