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    • 1. 发明申请
    • Ordered particle structures and methods of making same
    • 有序粒子结构及其制作方法
    • US20050228075A1
    • 2005-10-13
    • US10878656
    • 2004-06-28
    • Costas GogosMing-Wan YoungRajesh DaveRobert PfefferTheodore DavidsonDavid ToddBainian QianJun Yang
    • Costas GogosMing-Wan YoungRajesh DaveRobert PfefferTheodore DavidsonDavid ToddBainian QianJun Yang
    • C06B21/00C06B45/02C08J3/20C08K7/00C10L5/00D03D23/00
    • C08J3/20C06B21/0025C06B21/0083C06B45/02
    • Techniques and methods of formation of ordered mixtures of particles by “clustering”. Clustering comprises local “structuring” consisting of a large “host” and smaller “guest” particles by various techniques. Small amounts of polymer are coated onto solid particles by various means. In one embodiment, an ordered mixture is created wherein the material that is of lesser quantity is of small particle size (the “B” particles) and the “A” particles are of larger size. The “B” particles are then coated onto a single A particle. By creating this ordered structure, each composite particle has the proper or stoichiometric amount of all ingredients. This dry composite material produced is appropriately used in various applications such as pharmaceutical formulations in the form of tablets, capsules, oral suspensions, inhalant, parenteral formulations and the like; energetics manufacture such as but not limited to explosives, propellants and pyrotechnics; agricultural products including but not limited to fertilizers, herbicides and pesticides; nutritional supplements and the like.
    • 通过“聚类”形成有序粒子混合物的技术和方法。 聚类包括通过各种技术由大型“主机”和较小的“客体”粒子组成的本地“结构化”。 少量聚合物通过各种方式涂覆在固体颗粒上。 在一个实施方案中,产生有序混合物,其中少量的材料具有较小的粒度(“B”颗粒)和“A”颗粒的尺寸较大。 然后将“B”颗粒涂覆到单个A颗粒上。 通过创建这种有序结构,每个复合颗粒具有适当或化学计量的所有成分。 生产的这种干燥复合材料适用于各种应用,例如片剂,胶囊,口服悬浮液,吸入剂,肠胃外制剂等药物制剂; 能源制造,例如但不限于爆炸物,推进剂和烟火; 农产品包括但不限于化肥,除草剂和农药; 营养补品等。
    • 3. 发明申请
    • Dry coating and downstream processing of cohesive powders
    • 粘合粉末的干涂层和下游加工
    • US20070053846A1
    • 2007-03-08
    • US11512453
    • 2006-08-30
    • Rajesh DaveRobert PfefferJun YangYuhua Chen
    • Rajesh DaveRobert PfefferJun YangYuhua Chen
    • A61K9/28A61K9/14
    • C23C24/04A61J3/02B22F1/0062B22F2202/15B22F2304/15C09D5/033
    • The present disclosure is directed to systems and methods for dry particle coating of cohesive powders, and to the dry coated particles/powders produced thereby. The present disclosure is further directed to systems and methods for dry coating of cohesive particles, particularly nanosized particles, to provide enhanced flowability and other advantageous physical and/or functional properties. The disclosed systems and methods offer downstream processing advantages, e.g., for purposes of subsequent fluidization, coating, granulation and/or other particle processing operations, and have applicability in wide ranging industries, including specifically paint-related applications, pharmaceutical applications, food-related applications, cosmetic applications, defense-related applications, electronics-related applications, toner and ink-related applications, and the like.
    • 本公开涉及用于粘性粉末的干颗粒涂布的系统和方法以及由此产生的干涂层颗粒/粉末。 本公开进一步涉及用于干性涂布粘性颗粒,特别是纳米尺寸颗粒以提供增强的流动性和其它有利的物理和/或功能性质的系统和方法。 所公开的系统和方法提供下游处理优点,例如用于随后的流化,涂布,造粒和/或其它颗粒加工操作的目的,并且适用于广泛的行业,包括具体的油漆相关应用,药物应用,食品相关 应用,化妆品应用,国防相关应用,电子相关应用,调色剂和油墨相关应用等。