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1. 发明授权

US5690656A Method and apparatus for creating abdominal visceral anastomoses 失效
标题翻译：用于产生腹部内脏吻合的方法和装置
公开(公告)号：US5690656A
公开(公告)日：1997-11-25
申请号：US496125
申请日：1995-06-27
申请人： Constantin Cope , Hans A. Timmermans
发明人： Constantin Cope , Hans A. Timmermans
IPC分类号： A61B17/11 , A61B17/00
CPC分类号： A61B17/11 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1135 , A61B2017/1139
摘要： A method and apparatus for creating abdominal visceral anastomoses. A first magnet is placed within a first viscera and a second, larger magnet is placed within a second viscera. The magnets each have a raised rim around their perimeters. The two magnets couple to each other by virtue of their mutual attraction, thereby capturing a portion of the intervening visceral walls between them. The coupling of the magnets is automatically self-centering, as the smaller magnet is forced to rest within the raised rim of the larger magnet. Additionally, the raised rim of the smaller magnet acts as a fine cutting edge in order to accelerate the process of ischemic necrosis of the tissue captured between the two magnets, thereby forming the anastomosis. Use of the present invention avoids the need for general anasthesia and a laparotic incision, resulting in fewer surgical and post-surgical complications.
摘要翻译：一种用于产生腹部内脏吻合的方法和装置。将第一磁体放置在第一内脏内，并且将第二磁体放置在第二内脏内。磁铁每个都有围绕其周边的凸起边缘。这两个磁体由于它们的相互吸引力而相互耦合，从而在它们之间捕获一部分介入的内脏壁。磁体的耦合自动自动定心，因为较小的磁体被迫搁置在较大磁体的凸起边缘内。此外，较小磁体的凸起的边缘用作细切割边缘，以加速在两个磁体之间捕获的组织的缺血性坏死的过程，从而形成吻合。本发明的使用避免了一般的麻醉和腹腔切口的需要，导致较少的手术和手术后并发症。

2. 发明申请

US20050033238A1 Bloodless percutaneous insertion system 有权
标题翻译：无血经皮插入系统
公开(公告)号：US20050033238A1
公开(公告)日：2005-02-10
申请号：US10813806
申请日：2004-03-31
申请人： Constantin Cope , Mark Magnuson
发明人： Constantin Cope , Mark Magnuson
IPC分类号： A61M5/158 , A61M39/06 , A61M39/10 , A61M5/178
CPC分类号： A61M39/0606 , A61M5/158 , A61M39/10 , A61M2039/062
摘要： A system for permitting substantially bloodless percutaneous entry into an artery or vein of a patient. The system comprises a needle assembly, a needle hub attachment assembly having a hemostatic segment, and a wire guide inserter (curve straightener) or a wire guide holder also having a hemostatic segment. The components are assembled in a leak-free arrangement, and a fluid passageway for withdrawing blood is established through the system. Each of the hemostatic segments opens to permit passage of a wire guide therethrough, but re-seals to prevent flow of blood therethrough. The needle hub attachment assembly preferably includes a fluid-receiving chamber to permit the clinician to see the first squirt of blood as it enters the system.
摘要翻译：用于允许基本上无血的经皮进入患者的动脉或静脉的系统。该系统包括针组件，具有止血段的针座附接组件和还具有止血段的线引导插入器（曲线矫直机）或线引导器保持器。组件以无泄漏的方式组装，通过系统建立用于抽出血液的流体通道。每个止血片段打开以允许电线引导件通过其中，但是重新密封以防止血液通过其中。针毂连接组件优选地包括流体接收室，以允许临床医生在进入系统时看到第一次喷射的血液。

3. 发明授权

US06699263B2 Sliding suture anchor 有权
标题翻译：滑动缝合锚
公开(公告)号：US06699263B2
公开(公告)日：2004-03-02
申请号：US10116991
申请日：2002-04-05
申请人： Constantin Cope
发明人： Constantin Cope
IPC分类号： A61B1704
CPC分类号： A61D1/00 , A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0483 , A61B17/0487 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/061
摘要： A method and the apparatus for anastomosing two hollow viscera that can be performed percutaneously or through the patients mouth. The apparatus includes an anchor assembly including a stationary T-bar anchor secured to the distal end of a suture and a sliding anchor that is attached to the suture proximal to the stationary T-bar anchor. The sliding anchor is held in place on the suture but can be slid along the suture when pressure is applied to it. The anchor assembly is inserted through the abdominal wall, into the stomach, and then through the stomach into the jejunum. The stationary anchor is then released into the jejunum and the sliding anchor is released in the stomach. A pusher is then used to push or slide the sliding anchor distally until the tissue between the stationary and sliding anchors are in close contact. After the anchor has been placed, the suture can be severed at the sliding anchor.
摘要翻译：一种用于吻合两个中空内脏的方法和装置，其可以经皮或通过患者口进行。该装置包括锚固组件，该锚固组件包括固定到缝合线远端的固定T型杆锚固件和附接到靠近固定T型杆锚固件的缝合线的滑动锚固件。滑动锚固件保持在缝合线上的适当位置，但是当施加压力时可以沿缝合线滑动。锚固组件穿过腹壁插入胃中，然后穿过胃进入空肠。然后将固定锚释放到空肠中，并且滑动锚固体在胃中释放。然后使用推动器来推动或滑动滑动锚定器，直到固定和滑动锚定体之间的组织紧密接触。在放置锚定器之后，缝合线可以在滑动锚固件处切断。

4. 发明授权

US5123914A Visceral anchor for visceral wall mobilization 失效
标题翻译： VISCERAL锚杆用于粘性墙移动
公开(公告)号：US5123914A
公开(公告)日：1992-06-23
申请号：US864340
申请日：1986-05-19
申请人： Constantin Cope
发明人： Constantin Cope
IPC分类号： A61B17/00 , A61B17/02 , A61B17/04 , A61B17/32 , A61M27/00
CPC分类号： A61M27/00 , A61B17/0401 , A61B2017/0448 , A61B2017/0454 , A61B2017/0464
摘要： A visceral anchor and method for visceral wall mobilization is disclosed. The visceral anchor includes an elongated cross bar to which a suture is attached at a location substantially in the center of the cross bar. The cross bar further includes a helical spring sheath which jackets a rigid rod, the sheath extending beyond the ends of the rod to form flexible ends. An alternative embodiment includes a second suture attached to one of the ends of the cross bar. The sutures are used for orienting the anchor during insertion into and removal from a hollow viscus. The method of visceral wall mobilization includes providing a tract through the skin into a hollow intra-abdominal viscus and inserting the anchor into the viscus lumen. The sutures extend through the tract and the unattached ends remain on the outside of the body. The center suture is pulled to orient the anchor for mobilization of the visceral wall. The end suture is pulled to orient the anchor for removal.
摘要翻译：公开了一种用于内脏壁动员的内脏锚和方法。内脏锚固件包括细长的横杆，缝合线在基本上在横杆的中心的位置附接到该横杆上。横杆还包括螺旋弹簧护套，其夹持刚性杆，护套延伸超过杆的端部以形成柔性端部。替代实施例包括附接到横杆的一个端部的第二缝合线。缝合线用于在插入和从中空粘液中移除时定位锚固件。内脏壁动员的方法包括将穿过皮肤的管道提供到中空的腹内粘液中，并将锚固件插入到粘液腔中。缝合线延伸通过管道，未连接的端部保留在身体的外侧。中心缝合线被拉动以使锚固件定向以调动内脏壁。拉出端部缝合线以使锚固件定向以便移除。

5. 发明授权

US07544184B2 Bloodless percutaneous insertion system 有权
标题翻译：无血经皮插入系统
公开(公告)号：US07544184B2
公开(公告)日：2009-06-09
申请号：US10813806
申请日：2004-03-31
申请人： Constantin Cope , Mark A. Magnuson
发明人： Constantin Cope , Mark A. Magnuson
IPC分类号： A61M5/00
CPC分类号： A61M39/0606 , A61M5/158 , A61M39/10 , A61M2039/062
摘要： A system for permitting substantially bloodless percutaneous entry into an artery or vein of a patient. The system comprises a needle assembly, a needle hub attachment assembly having a hemostatic segment, and a wire guide inserter (curve straightener) or a wire guide holder also having a hemostatic segment. The components are assembled in a leak-free arrangement, and a fluid passageway for withdrawing blood is established through the system. Each of the hemostatic segments opens to permit passage of a wire guide therethrough, but re-seals to prevent flow of blood therethrough. The needle hub attachment assembly preferably includes a fluid-receiving chamber to permit the clinician to see the first squirt of blood as it enters the system.
摘要翻译：用于允许基本上无血的经皮进入患者的动脉或静脉的系统。该系统包括针组件，具有止血段的针座附接组件和还具有止血段的线引导插入器（曲线矫直机）或线引导器保持器。组件以无泄漏的方式组装，通过系统建立用于抽出血液的流体通道。每个止血片段打开以允许电线引导件通过其中，但是重新密封以防止血液通过其中。针毂连接组件优选地包括流体接收室，以允许临床医生在进入系统时看到第一次喷射的血液。

6. 发明授权

US6110183A Suture anchor device 有权
标题翻译：缝合锚装置
公开(公告)号：US6110183A
公开(公告)日：2000-08-29
申请号：US219330
申请日：1998-12-22
申请人： Constantin Cope
发明人： Constantin Cope
IPC分类号： A61B17/04 , A61B17/06 , A61B17/34 , A61B17/00
CPC分类号： A61B17/0401 , A61B17/0483 , A61B17/3417 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/06052 , A61B2017/061
摘要： A suture anchor device, a visceral anchor for anchoring a viscus to a body wall, a kit for anchoring a viscus to a body wall and a method for anchoring a viscus to a body wall are described. The method and device reduce the probability of injuring the interior of a viscus as a large gauge needle is not required to deliver the visceral anchor. In one embodiment, the distal end of the visceral anchor may function as a dilator.
摘要翻译：描述了缝合锚定装置，用于将粘液锚定到体壁的内脏锚固件，用于将粘液锚定到体壁的试剂盒和用于将粘液锚定到体壁的方法。该方法和装置降低了在不需要大规格针头输送内脏锚的情况下损伤粘液内部的可能性。在一个实施例中，内脏锚的远端可用作扩张器。

7. 发明授权

US5776079A Retrograde-antegrade catheterization guide wire 失效
标题翻译：逆行顺行导管插入导丝
公开(公告)号：US5776079A
公开(公告)日：1998-07-07
申请号：US692568
申请日：1996-08-06
申请人： Constantin Cope , Mark A. Griffin
发明人： Constantin Cope , Mark A. Griffin
IPC分类号： A61M25/01 , A61M25/09
CPC分类号： A61M25/0152 , A61M25/09 , A61M2025/09083
摘要： An catheterization apparatus 10 for reversing the retrograde or antegrade direction of catheterization includes a guide wire 12 foldable upon itself for partial introduction into a vessel 68 of a patient. The guide wire 12 first includes a resilient, elongated member 14 having a curved end 16 and a remainder 17 having a second, bent end 18. The guide wire 12 also includes a flexible tether 22 connected to the tip 20 of the curved end 16 of the elongated member 14. The elongated member 14 is preferably formed from a wire core or mandrel 24 covered by a continuous coiled wire 30. The catheterization apparatus 10 preferably further includes a catheter through which the guide wire 12 is introduced into the vessel 68. The catheter can be of conventional construction and operability. Preferably, however, the catheter is a highly flexible and relatively short intermediary catheter 56, employed only temporarily during use of the retrograde-antegrade guide wire 12. The catheterization apparatus 10 can also include an inserter sheath 60 engageable with the catheter 56 to facilitate passage of the guide wire 12 through the catheter 56. The apparatus 10 is particularly advantageous in that its use avoids the need to establish a second access site. Moreover, the apparatus 10 is relatively simple and reliable in construction and use, and is relatively low in cost, at least in comparison to the costs and risks of the establishment of a second access site. The apparatus 10 is atraumatic during use, that is, it does not significantly damage the blood vessel or other vessel during reversal of the direction of catheterization. The apparatus 10 is useful in vessels of both large and small diameter, and facilitates the selective engagement of a catheter with a bifurcation branch in a vessel.
摘要翻译：用于反转导尿术的逆行或顺行方向的导管插入装置10包括可自行折叠的引导线12，以部分地引入患者血管68。导丝12首先包括具有弯曲端部16的弹性细长构件14，其余部分17具有第二弯曲端18.引导线12还包括柔性系绳22，其连接到弯曲端16的尖端20 细长构件14优选地由被连续卷绕的线30覆盖的线芯或心轴24形成。导管插入装置10优选地还包括导管，引导线12通过该导管引入容器68中。导管可以是常规的结构和可操作性。然而，优选地，导管是高度柔性且相对短的中间导管56，其仅在使用逆行顺行导丝12期间临时使用。导管插入装置10还可以包括可与导管56接合以便于通过的插入器护套60 引导线12通过导管56.装置10是特别有利的，因为其用途避免了建立第二进入位置的需要。此外，装置10在建造和使用中相对简单和可靠，并且成本相对较低，至少与建立第二进入站点的成本和风险相比较。装置10在使用过程中是无创伤的，也就是说，在导尿术方向的反转过程中，它不会显着损伤血管或其他血管。装置10可用于大直径和小直径的容器中，并且有利于导管与容器中的分叉支路的选择性接合。

8. 发明授权

US5064428A Medical retrieval basket 失效
标题翻译：医疗检索篮
公开(公告)号：US5064428A
公开(公告)日：1991-11-12
申请号：US584474
申请日：1990-09-18
申请人： Constantin Cope , Scott E. Boatman , Joseph W. Roberts
发明人： Constantin Cope , Scott E. Boatman , Joseph W. Roberts
IPC分类号： A61B17/22 , A61F2/00
CPC分类号： A61B17/221 , A61B2017/2212 , A61F2002/30093 , A61F2210/0019
摘要： A stone retrieval basket having superelastic metallic alloy wires attached to the distal end of an inner elongaged member tube for retrieving calculi and crushing them against an outer introducer tube percutaneously inserted into a patient. The basket comprises kink-resistant superelastic metallic alloy wires such as nitinol forming a bulbous shape for capturing calculi therein. The ends of the superelastic wires of the basket are attached to the distal end of a inner elongated member tube with the aid of sleeves crimped thereon, which are soldered or spot welded in recesses about the distal end of the inner tube. The outer tube is percutaneously inserted into the biliary or urinary system in which the basket is then inserted to capture large-sized stones. A peel-away sheath is also included to introduce the basket and inner elongatged member tube into the outer introducer tube. A dilator member, which is extendable through the passageway of the inner tube, removes any residual debris from the tube that may be left during the stone removal procedure.
摘要翻译：一种具有超弹性金属合金线的石材回收篮，其连接到内部延伸构件管的远端，用于回收结石并将其压碎经皮插入患者体内的外导引管。篮子包括抗扭的超弹性金属合金线，例如镍钛诺，形成用于在其中捕获结石的球形形状。篮子的超弹性线的端部借助于压接在其上的套筒附接到内部细长构件管的远端，该套管被焊接或点焊在内管的远端周围的凹部中。外管经皮插入到胆汁或泌尿系统中，其中篮子被插入以捕获大尺寸的石头。还包括剥离护套以将筐和内部延伸的构件管引入外导引管中。通过内管的通道延伸的扩张器构件可以在除石过程期间从管中去除残留的碎屑。

9. 发明授权

US5011478A Recessed dilator-sheath assembly and method 失效
标题翻译：嵌入式扩张器鞘组件及方法
公开(公告)号：US5011478A
公开(公告)日：1991-04-30
申请号：US304667
申请日：1989-01-31
申请人： Constantin Cope
发明人： Constantin Cope
IPC分类号： A61M25/00 , A61M25/01 , A61M25/06 , A61M25/08
CPC分类号： A61M25/0668 , A61M25/0662 , A61M2025/0687
摘要： An introducer set including a sheath and dilator is formed within a heated mold to form a smooth external shape on the set. The distal end of the sheath is embedded in the dilator and also formed at an angle oblique to the longitudinal axis of the introducer set. This construction permits the sheath to be inserted into the body with a minimum of trauma to the patient and also permits easy removal of the sheath from the dilator.

10. 发明授权

US5499975A Smooth transitioned dilator-sheath assembly and method 失效
标题翻译：平滑过渡的扩张器 - 鞘组件和方法
公开(公告)号：US5499975A
公开(公告)日：1996-03-19
申请号：US169508
申请日：1993-12-17
申请人： Constantin Cope , Patty J. Arnett
发明人： Constantin Cope , Patty J. Arnett
IPC分类号： A61M25/06 , A61M39/00 , A61M5/00
CPC分类号： A61M25/0662 , A61M25/0668 , A61M2025/0687
摘要： An introducer set including a sheath and dilator is formed within a heated mold to form a smooth external shape on the set. In one embodiment, the distal end of the sheath is embedded in the dilator and also formed at an angle oblique to the longitudinal axis of the introducer set. In a second embodiment, the distal end of the sheath contacts the dilator at a ledge or lip formed in the dilator, but is not recessed into the dilator at the ledge portion. The outer diameter of the dilator at the transition is formed relatively the same as the distal tip of the sheath so as to provide a smooth transition between the sheath and the dilator. This construction permits the sheath to be inserted into the body with a minimum of trauma to the patient and also permits easy removal of the sheath from the dilator.
摘要翻译：在加热的模具内形成包括护套和扩张器的导引器组，以在组上形成平滑的外部形状。在一个实施例中，护套的远端嵌入扩张器中并且还以与导引器组的纵向轴线倾斜的角度形成。在第二实施例中，鞘的远端在扩张器中形成的凸缘或唇缘处与扩张器接触，但是在凸缘部分处不会凹入扩张器。在过渡处的扩张器的外径形成为与护套的远端相同地相同，以便在护套和扩张器之间提供平滑的过渡。这种结构允许护套以最小的对患者的创伤插入身体，并且还允许从扩张器容易地移除护套。

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