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    • 3. 发明申请
    • Microwave-assisted chromatography preparation
    • 微波辅助色谱法制备
    • US20060038118A1
    • 2006-02-23
    • US10923243
    • 2004-08-20
    • Michael CollinsWyatt HargettJames ThomasMichael CollinsE. Barnhardt
    • Michael CollinsWyatt HargettJames ThomasMichael CollinsE. Barnhardt
    • H05H3/02
    • H05B6/806F26B3/347F26B5/048F26B9/003F26B21/14G01N1/44G01N30/06G01N2030/567
    • An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
    • 公开了用于制备用于柱色谱法的样品的仪器和相关方法。 该方法包括以下步骤:向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物,然后将吸收介质与样品混合以吸收溶剂,该介质与液相色谱相容, 将期望的产品分离,对预期产品具有化学惰性,并且以足以提供介质和样品的基本上干燥的混合物的量加入,但小于在液相色谱法过度扩大样品分辨率的量, 然后将微波能量施加到介质和样品的干燥混合物中,从而促使溶剂在微波能量的影响下蒸发,然后将介质和剩余样品的干混合物加入液相色谱柱中, 剩余样品的组分用于鉴定和纯化目的。
    • 6. 发明申请
    • Microwave-Assisted Chromatography Preparation
    • 微波辅助色谱法制备
    • US20060261058A1
    • 2006-11-23
    • US11456997
    • 2006-07-12
    • Michael CollinsWyatt HargettJames ThomasMichael CollinsE. Barnhardt
    • Michael CollinsWyatt HargettJames ThomasMichael CollinsE. Barnhardt
    • B01L9/00
    • H05B6/806F26B3/347F26B5/048F26B9/003F26B21/14G01N1/44G01N30/06G01N2030/567
    • An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
    • 公开了用于制备用于柱色谱法的样品的仪器和相关方法。 该方法包括以下步骤:向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物,然后将吸收介质与样品混合以吸收溶剂,该介质与液相色谱相容, 将期望的产品分离,对预期产品具有化学惰性,并且以足以提供介质和样品的基本上干燥的混合物的量加入,但小于在液相色谱法过度扩大样品分辨率的量, 然后将微波能量施加到介质和样品的干燥混合物中,从而促使溶剂在微波能量的影响下蒸发,然后将介质和剩余样品的干混合物加入液相色谱柱中, 剩余样品的组分用于鉴定和纯化目的。
    • 9. 发明授权
    • Dental implant prosthetic device with improved osseointegration and esthetic features
    • 具有改善的骨整合和美观特征的牙种植体假体装置
    • US08814567B2
    • 2014-08-26
    • US11847476
    • 2007-08-30
    • Kai ZhangMichael WallickJeffrey A. BassettMichael Collins
    • Kai ZhangMichael WallickJeffrey A. BassettMichael Collins
    • A61C8/00
    • A61C8/0012A61C8/0006
    • Dental implants made at least in part of a porous tantalum material for enhancing the osseointegration of the dental implant into surrounding bone. For example, there is provided a dental implant which includes a porous tantalum portion and an outer portion having a color generally replicating the color of natural teeth. The dental implant further comprises a core portion and the porous tantalum portion at least partially surrounds the core portion. An esthetic portion is disposed at least the outer portion and the porous tantalum portion is disposed for at least partially reinforcing the esthetic portion. After implantation of the implant, bone tissue may osseointegrate into the porous tantalum portion to anchor the implant in position within the surrounding bone. Other embodiments of implants are provided, each implant including at least a portion thereof formed of porous tantalum for improved osseointegration.
    • 至少部分由多孔钽材料制成的牙种植体,用于增强牙科植入物到骨骼的骨整合。 例如,提供了一种牙科植入物,其包括多孔钽部分和具有通常复制天然颜色的颜色的外部部分。 牙科植入物还包括芯部分,并且多孔钽部分至少部分地围绕芯部分。 至少设置有外观部分的美观部分,多孔钽部分设置成至少部分地加强美观部分。 在植入植入物之后,骨组织可以骨整合到多孔钽部分中以将植入物锚定在周围骨骼内的适当位置。 提供植入物的其它实施方案,每个植入物包括由多孔钽形成的至少一部分,用于改善骨整合。