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1. 发明授权

US10184891B2 Biochip device 有权
公开(公告)号：US10184891B2
公开(公告)日：2019-01-22
申请号：US13976596
申请日：2011-12-28
申请人： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Christof Schafauer , Gabriel Sagarzazu , Thierry Gacoin , Mélanie Bedu
发明人： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Christof Schafauer , Gabriel Sagarzazu , Thierry Gacoin , Mélanie Bedu
IPC分类号： G01N21/77 , G01N21/64 , G01N21/47 , G01N21/55
摘要： A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.

2. 发明申请

US20140017128A1 BIOCHIP DEVICE 审中-公开
标题翻译：生物设备
公开(公告)号：US20140017128A1
公开(公告)日：2014-01-16
申请号：US13976596
申请日：2011-12-28
申请人： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Thierry Gacoin , Christof Schafauer , Gabriel Sagarzazu , Mélanie Bedu
发明人： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Thierry Gacoin , Christof Schafauer , Gabriel Sagarzazu , Mélanie Bedu
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/47 , G01N21/6456 , G01N21/648 , G01N21/7703
摘要： A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.
摘要翻译：一种生物芯片装置，包括由形成多模平面波导的至少一种材料板构成的基板，并且载体适于响应于具有ev逝部分的导波的激发而发射荧光的发色团元件，该装置的特征在于，其包括用于将激发光与导波形式的波导耦合，耦合装置基本上是无方向的。

3. 发明申请

US20130230906A1 MICROFLUID CARTRIDGE FOR MOLECULAR DIAGNOSTICS 审中-公开
标题翻译：用于分子诊断的MICROFLUID CARTRIDGE
公开(公告)号：US20130230906A1
公开(公告)日：2013-09-05
申请号：US13885507
申请日：2011-11-16
申请人： Lucio Martinelli , Marc Artigue , Yann Marcy , Christof Schafauer
发明人： Lucio Martinelli , Marc Artigue , Yann Marcy , Christof Schafauer
IPC分类号： G01N1/28
CPC分类号： G01N1/28 , B01L3/502738 , B01L2300/0636 , B01L2300/0816 , B01L2400/0655
摘要： A cartridge for carrying out a method of analyzing the nucleic acids contained in a sample, includes a main body (1) produced in a substrate, in which there are formed at least one reaction chamber (6) and one detection chamber (10) for at least one nucleic acid likely to be contained in the sample, a microfluid circuit including a sample-injection member (7), elements (4 and 13) for respectively injecting fluids into and removing fluids from the cartridge, cavities, fluidic passages (2) and valves capable of closing them. The cartridge further includes (a) a first face known as the actuation face (16), from which the valves of the cartridge are actuated, and (b) a second face, opposite to the actuating face, including the detection chamber (10) for at least one nucleic acid likely to be contained in the sample, this face being known as the detection face (15).
摘要翻译：用于进行分析样品中所含的核酸的方法的盒包括在基板中制造的主体（1），其中形成有至少一个反应室（6）和一个检测室（10），用于至少一种可能包含在样品中的核酸，包括样品注射构件（7）的微流体回路，用于分别将流体输入和移出流体的元件（4和13），空腔，流体通道（2））和能够关闭它们的阀。该盒还包括（a）被称为致动面（16）的第一面，盒的阀被致动，和（b）与致动面相对的第二面，包括检测室（10）对于可能包含在样品中的至少一种核酸，该面被称为检测面（15）。

4. 发明申请

US20110266460A1 Method and a Device for Detecting the Fluorescence of a Biochip 有权
标题翻译：用于检测生物芯片荧光的方法和装置
公开(公告)号：US20110266460A1
公开(公告)日：2011-11-03
申请号：US13000549
申请日：2009-06-23
申请人： Lucio Martinelli , Yann Marcy , Henri Benisty
发明人： Lucio Martinelli , Yann Marcy , Henri Benisty
IPC分类号： G01N21/64
CPC分类号： G01N21/6454
摘要： An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.
摘要翻译：一种成像方法和装置，用于通过照射与放置在具有光电探测器的传感器（10）上的基底（12）的探针（14）相关联的发色团来检测生物芯片的荧光。的CCD或CMOS类型的阻挡滤光器，其阻止在探针（14）和传感器之间提供的发色团的激发光，基板（12）在使用后可与传感器（10）分离，以使得能够传感器被重复使用。

5. 发明授权

US08440985B2 Method and a device for detecting the fluorescence of a biochip 有权
标题翻译：用于检测生物芯片的荧光的方法和装置
公开(公告)号：US08440985B2
公开(公告)日：2013-05-14
申请号：US13000549
申请日：2009-06-23
申请人： Lucio Martinelli , Yann Marcy , Henri Benisty
发明人： Lucio Martinelli , Yann Marcy , Henri Benisty
IPC分类号： G01N21/64
CPC分类号： G01N21/6454
摘要： An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.
摘要翻译：一种成像方法和装置，用于通过照射与放置在具有光电探测器的传感器（10）上的基底（12）的探针（14）相关联的发色团来检测生物芯片的荧光。的CCD或CMOS类型的阻挡滤光器，其阻止在探针（14）和传感器之间提供的发色团的激发光，基板（12）在使用后可与传感器（10）分离，以使得能够传感器被重复使用。

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