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    • 3. 发明申请
    • PROCESS FOR THE PREPARATION OF FUROPYRROLES
    • 制备呋喃甲醇的方法
    • WO2005005430A2
    • 2005-01-20
    • PCT/EP2004/051259
    • 2004-06-28
    • CIBA SPECIALTY CHEMICALS HOLDING INC.RIGGS, Richard LewisWESTWOOD, Nicholas JamesSMITH, David MacdonaldMORTON, Colin
    • RIGGS, Richard LewisWESTWOOD, Nicholas JamesSMITH, David MacdonaldMORTON, Colin
    • C07D491/00
    • C07D487/04C07D491/04
    • The present invention relates to a process for the preparation of furopyrroles of the general formula (I), comprising (a) heating a compound of the formula (II) under microwave irradiation optionally in the presence of an inert solvent, wherein A 1 and A 2 are C l -C 18 alkyl, C 2 -C l8 alkenyl, C 2 -C l8 alkynyl, C 5 -C 8 cycloalkyl, C 5- C 8 cycloalkenyl, aryl or heteroaryl, A 3 is hydrogen, C 1 -C 18 alkyl, cyanomethyl, Ar 3 ,-CR 30 R 31 -(CH 2 ) m -Ar 3 or Y- R 32 , wherein R 30 and R 31 independently of each other stand for hydrogen or C 1 -C 4 alkyl, or phenyl which can be substituted up to three times with C 1 -C 4 alkyl, Ar 3 stands for aryl, C 5 -C 8 cloalkyl, C 5 -C 8 cycloalkenyl or heteroaryl, which can be substituted one to three times with C 1 -C 8 alkyl, C 1 -C 8 alkoxy, halogen or phenyl, which can be substituted with C 1 -C 8 alkyI or C 1 -C 8 alkoxy one to three times, and m stands for 0, 1, 2, 3 or 4, R is C 1 -C 18 alkyl, in particular C 1 -C 4 alkyl, aryl, in particular phenyl, or aralkyl, in particular benzyl, which can be substituted one to three times with C 1 -C 8 alkyl, C 1 -C 8 alkoxy, or halogen, Y is -C(O)-, -C(O)O-, -C(O)NH-, -SO 2 NH- or -SO 2 - and R 32 is C 1 -C l8 alkyl, Ar 3 , or aralkyl. The furopyrroles of the general formula (I) can be obtained in high yield and high purity by the process of the present invention.
    • 本发明涉及制备通式(I)呋喃并呋喃的方法,其包括(a)在微波辐射下任选地在存在下式(II)的情况下加热式 惰性溶剂,其中A 1和A 2是C 1 -C 18烷基,C≡2 -C≡C8烯基,C≡C12炔基,C≡C-sub C8-C8环烯基,芳基或杂芳基,A 3是氢,C 1 -C 8环烷基,C 5 -C 8环烯基,芳基或杂芳基,A 3是氢,C≡1 C18烷基,氰甲基,Ar 3,-CR 30 R 31 - (CH 3) - , - CH 2),或者Y-R <32>,或者Y-R <32> 其中R 30和R 31彼此独立地代表氢或C 1 -C 4 - / - ,其中R 30和R 31彼此独立地代表氢或C 1 -C 4 - 烷基或可被C 1 -C 4烷基取代至多三次的苯基,Ar 3代表芳基,C 1 -C 4烷基, 低于5-C 8 cloa C 1 -C 8 - 环烯基或杂芳基,其可以被C 1 -C 8取代1-3次, C 1-8烷基,C 1 -C 8烷氧基,卤素或可被C 1 -C 8取代的苯基 烷基或C 1 -C 8烷氧基取代1-3次,m代表0,1,2,3或4,R是C
    • 4. 发明申请
    • PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES
    • 制备二氯丙烯的方法
    • WO2003022848A2
    • 2003-03-20
    • PCT/EP2002/009792
    • 2002-09-03
    • CIBA SPECIALTY CHEMICALS HOLDING INC.MORTON, ColinSMITH, David, MacdonaldRUFFIEUX, Vincent
    • MORTON, ColinSMITH, David, MacdonaldRUFFIEUX, Vincent
    • C07D487/04
    • C07D487/04C07D491/04C09B57/004C09B67/0039C09K11/06C09K2211/1011C09K2211/1033C09K2211/1044
    • The present invention relates to a process for the preparation of diketopyrrolopyrroles of the formula (I), wherein A 1, A2, A3 and A4 are as defined in the description of the present invention, to new diketopyrrolopyrroles of the general formula I obtainable by the process, and the use of the new diketopyrrolopyrroles of the general formula I for the preparation of inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, dye lasers and electroluminescent devices, or as fluorescent markers for immunoassays and fluorescent tracers for leak detection of fluids. Furthermore the present invention relates to diketopyrrolopyrrole analogues of the general formula (II), wherein A1, A2 and A3 are defined in the description of the present invention, which are intermediates in the process for the preparation of diketopyrrolopyrroles of the formula I and can be used as crystal growth regulators.
    • 本发明涉及一种制备式(I)的二酮吡咯并吡咯的方法,其中A 1,A 2,A 3和A 4如本发明的描述中所定义,可通过下式获得通式I的新的二酮吡咯并吡咯 方法和使用通式I的新型二酮吡咯并吡咯,用于制备油墨,着色剂,用于涂料的着色塑料,非冲击印刷材料,滤色器,化妆品,聚合物墨颗粒,调色剂,染料激光和电致发光装置 ,或作为荧光标记物用于免疫测定和荧光示踪剂,用于检测流体。 此外,本发明涉及通式(II)的二酮吡咯并吡咯类似物,其中A1,A2和A3在本发明的说明书中定义,其是制备式I的二酮吡咯并吡咯吡咯的方法中的中间体,并且可以是 用作晶体生长调节剂。
    • 8. 发明申请
    • FLUORESCENT DIKETOPYRROLOPYRROLE ANALOGUES
    • 荧光酮衍生物类似物
    • WO2003014255A1
    • 2003-02-20
    • PCT/EP2002/008590
    • 2002-08-01
    • CIBA SPECIALTY CHEMICALS HOLDING INC.MORTON, ColinSMITH, David, MacdonaldIQBAL, Abul
    • MORTON, ColinSMITH, David, MacdonaldIQBAL, Abul
    • C09K11/06
    • C09K11/06C07D239/96C09B57/004C09K2211/1011C09K2211/1029
    • The present invention relates to fluorescent diketopyrrolopyrrole analogues of the general formula (I), wherein A 1 and A 2 are C 1 -C 18 alkyl, C 2 -C 18 alkenyl, C 2 -C 18 alkynyl, C 5 -C 8 cycloalkyl, C 5 -C 8 cycloalkenyl, aryl or heteroaryl, A 3 and A 4 are independently of each other C 1 -C 18 alkyl, Ar 3 , -CR 30 R 31 -(CH 2 ) m -Ar 3 , or Y-R 32 , wherein R 30 and R 31 independently of each other stand for hydrogen or C 1 -C 4 alkyl, or phenyl which can be substituted up to three times with C 1 -C 3 alkyl, Ar 3 stands for aryl, in particular phenyl or 1- or 2-naphthyl, C 5 -C 8 cycloalkyl, in particular cyclohexyl, or heteroaryl, which can be sustituted one to three times with C 1 -C 8 alkyl, C 1 -C 8 alkoxy, halogen or phenyl, which can be substituted with C 1 -C 8 alkyl or C 1 -C 8 alkoxy one to three times, and m stands for 0, 1, 2, 3 or 4, Y is C(O)- or SO 2 - and R 32 is C 1 -C 18 alkyl, Ar 3 , or aralkyl and A 3 can additionally be hydrogen, C 1 -C 8 alkyloxycarbonyl, such as tertbutoxycarbonyl, or aralkyloxycarbonyl, such as benzyloxycarbonyl, a process for their preparation and their use for the preparation of inks, colourants, pigmented plastics for coatings, non-impact printing material, colour filters, cosmetics, polymeric ink particles, toners, dye lasers and electroluminescent devices, or as fluorescent markers for immunoassays and fluorescent tracers for leak detection of fluids. The diketopyrrolopyrrole analogues of the general formula I show a high solid state fluorescence.
    • 本发明涉及通式(I)的荧光二酮吡咯并吡咯类似物,其中A 1和A 2是C 1 -C 18烷基,C 2 -C 18烯基,C 2 -C 18炔基,C 5 -C 8环烷基,C 5 -C 8环烯基,芳基或杂芳基 ,A 3和A 4彼此独立地为C 1 -C 18烷基,Ar 3,-CR 30 R 31 - (CH 2)m -Ar 3或YR 32, 其中R 30和R 31彼此独立地代表氢或C 1 -C 4烷基,或可以被C 1 -C 3烷基取代至多三次的苯基,Ar 3代表芳基,特别是苯基或1 - 或2-萘基,C 5 -C 8环烷基,特别是环己基或杂芳基,其可以被可被C 1 -C 8烷基或C 1 -C 8烷氧基取代的C 1 -C 8烷基,C 1 -C 8烷氧基,卤素或苯基取代1至3倍 一至三次,m代表0,1,2,3或4,Y是C(O) - 或SO 2 - ,R 32是C 1 -C 18烷基,Ar 3或芳烷基和A 3 >另外可以是氢,C 1 -C 8烷氧基羰基,如叔丁氧基羰基或芳烷氧基羰基,如b 酶氧羰基,其制备方法及其用于制备油墨,着色剂,用于涂料的着色塑料,非冲击性印刷材料,滤色器,化妆品,聚合物墨颗粒,调色剂,染料激光和电致发光器件的用途,或作为荧光标记 用于免疫测定和荧光示踪剂,用于检测流体。 通式I的二酮吡咯并吡咯类似物显示高固态荧光。
    • 10. 发明公开
    • FLUORESCENT DIKETOPYRROLOPYRROLE ANALOGUES
    • 荧光化合物用于模拟DIKETOPYRROLLOPYRROLEN
    • EP1432777A1
    • 2004-06-30
    • EP02758423.4
    • 2002-08-01
    • Ciba Specialty Chemicals Holding Inc.
    • MORTON, ColinSMITH, David, MacdonaldIQBAL, Abul
    • C09K11/06C07D487/04C08K5/3415C09B57/00
    • C09K11/06C07D239/96C09B57/004C09K2211/1011C09K2211/1029
    • The present invention relates to fluorescent diketopyrrolopyrrole analogues of the general formula (I), wherein A?1 and A2¿ are C¿1?-C18alkyl, C2-C18alkenyl, C2-C18alkynyl, C5-C8cycloalkyl, C5-C8cycloalkenyl, aryl or heteroaryl, A?3 and A4¿ are independently of each other C¿1?-C18alkyl, Ar?3, -CR30R31-(CH¿2)m-Ar3, or Y-R32, wherein R?30 and R31¿ independently of each other stand for hydrogen or C¿1?-C4alkyl, or phenyl which can be substituted up to three times with C1-C3alkyl, Ar?3¿ stands for aryl, in particular phenyl or 1- or 2-naphthyl, C¿5?-C8cycloalkyl, in particular cyclohexyl, or heteroaryl, which can be sustituted one to three times with C1-C8alkyl, C1-C8alkoxy, halogen or phenyl, which can be substituted with C1-C8alkyl or C1-C8alkoxy one to three times, and m stands for 0, 1, 2, 3 or 4, Y is C(O)- or SO2- and R?32 is C¿1-C18alkyl, Ar3, or aralkyl and A3 can additionally be hydrogen, C¿1?-C8alkyloxycarbonyl, such as tertbutoxycarbonyl, or aralkyloxycarbonyl, such as benzyloxycarbonyl, a process for their preparation and their use for the preparation of inks, colourants, pigmented plastics for coatings, non-impact printing material, colour filters, cosmetics, polymeric ink particles, toners, dye lasers and electroluminescent devices, or as fluorescent markers for immunoassays and fluorescent tracers for leak detection of fluids. The diketopyrrolopyrrole analogues of the general formula I show a high solid state fluorescence.