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1. 发明授权

US08426577B2 Promoter and a production method for L-lysine using the same 有权
标题翻译：启动子和使用其的L-赖氨酸的制备方法
公开(公告)号：US08426577B2
公开(公告)日：2013-04-23
申请号：US12864731
申请日：2009-01-23
申请人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , Jun Ok Moon , Gey Hang Jeon , Jin Suk Sung
发明人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , Jun Ok Moon , Gey Hang Jeon , Jin Suk Sung
IPC分类号： C07H21/04 , C12P13/08 , C12N1/12
CPC分类号： C12P13/08 , C12N9/0008 , C12N9/1217
摘要： Disclosed are a nucleic acid molecule of Corynebacterium glutamicum origin, having an improved promoter activity, which is operably linked to operon encoding aspartate kinase and aspartate semialdehyde dehydrogense, a vector containing the same, a transformant transformed with the vector, and a method for the production of L-lysine using the transformant.
摘要翻译：公开了具有改良的启动子活性的谷氨酸棒杆菌起源的核酸分子，其可操作地连接到编码天冬氨酸激酶和天冬氨酸半醛脱氢酶的操纵子，含有它的载体，用载体转化的转化体，以及生产方法的L-赖氨酸。

2. 发明申请

US20100317067A1 PROMOTER AND A PRODUCTION METHOD FOR L-LYSINE USING THE SAME 有权
标题翻译：促进剂和使用它的L-赖氨酸的生产方法
公开(公告)号：US20100317067A1
公开(公告)日：2010-12-16
申请号：US12864731
申请日：2009-01-23
申请人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , Jun Ok Moon , Gey Hang Jeon , Jin Suk Sung
发明人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , Jun Ok Moon , Gey Hang Jeon , Jin Suk Sung
IPC分类号： C12P13/08 , C12N15/54 , C12N15/53 , C12N15/63 , C12N1/00 , C12N1/21
CPC分类号： C12P13/08 , C12N9/0008 , C12N9/1217
摘要： Disclosed are a nucleic acid molecule of Corynebacterium glutamicum origin, having an improved promoter activity, which is operably linked to operon encoding aspartate kinase and aspartate semialdehyde dehydrogense, a vector containing the same, a transformant transformed with the vector, and a method for the production of L-lysine using the transformant.
摘要翻译：公开了具有改良的启动子活性的谷氨酸棒杆菌起源的核酸分子，其可操作地连接到编码天冬氨酸激酶和天冬氨酸半醛脱氢酶的操纵子，含有它的载体，用载体转化的转化体，以及生产方法的L-赖氨酸。

3. 发明授权

US08535915B2 Promoter, and a production method for L-lysine using the same 有权
标题翻译：促进剂和使用其的L-赖氨酸的制备方法
公开(公告)号：US08535915B2
公开(公告)日：2013-09-17
申请号：US12864979
申请日：2009-01-23
申请人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , So Yeon Rah , Gey Hang Jeon
发明人： Chul Ha Kim , Jong Soo Choi , Sang Jo Lim , Hyung Joon Kim , So Yeon Rah , Gey Hang Jeon
IPC分类号： C12P13/08 , C12N15/11 , C12N1/21
CPC分类号： C12N15/77 , C12P13/08
摘要： Disclosed are a nucleic acid molecule of Corynebacterium glutamicum origin, having an improved promoter activity, which is operably linked to a gene encoding diaminopimelate dehydrogenase, a vector containing the same, a transformant transformed with the vector, and a method for the production of L-lysine using the transformant.
摘要翻译：公开了具有改善的启动子活性的谷氨酸棒杆菌起源的核酸分子，其与编码二氨基庚二酸脱氢酶的基因，含有其的载体，用该载体转化的转化体可操作地连接，赖氨酸使用转化体。

4. 发明授权

US08551736B2 Inosine producing microorganism belonging to the genus Corynebacterium and process of producing inosine using the same 有权
标题翻译：产于棒杆菌属的产生肌苷的微生物及使用其产生肌苷的方法
公开(公告)号：US08551736B2
公开(公告)日：2013-10-08
申请号：US12811778
申请日：2009-01-02
申请人： Chul Ha Kim , Jong Soo Choi , Jeong Hwan Kim , Hyoung Seok Kim , Jung Gun Kwon , Tae Min Ahn , Soo Youn Hwang , Jae Ick Sim , Min Ji Baek , Na Ra Kwon , Hye Jin Choi
发明人： Chul Ha Kim , Jong Soo Choi , Jeong Hwan Kim , Hyoung Seok Kim , Jung Gun Kwon , Tae Min Ahn , Soo Youn Hwang , Jae Ick Sim , Min Ji Baek , Na Ra Kwon , Hye Jin Choi
IPC分类号： C12P19/40 , C12P19/28 , C12P19/26 , C12P19/00 , C12P1/00
CPC分类号： C12P19/40 , C12N9/2497 , C12Y302/02001 , C12Y302/02008
摘要： A microorganism of the genus Corynebacterium having the ability to produce inosine in which the inosine catabolic pathway is blocked and that has a leaky adenine auxotrophic phenotype and further has a leaky guanine auxotrophic phenotype and a method of producing inosine, the method including culturing the microorganism of the genus Corynebacterium are disclosed.
摘要翻译：能够产生肌苷分解代谢途径被阻断并具有渗漏的腺嘌呤营养缺陷型的肌氨酸杆菌属的微生物，并且还具有泄漏的鸟嘌呤营养缺陷型表型和产生肌苷的方法，该方法包括培养微生物披露了棒状杆菌属。

5. 发明申请

US20110003342A1 INOSINE PRODUCING MICROORGANISM BELONGING TO THE GENUS CORYNEBACTERIUM AND PROCESS OF PRODUCING INOSINE USING THE SAME 有权
标题翻译：生产与根瘤菌相关的微生物的生产和使用其生产异辛烯的方法
公开(公告)号：US20110003342A1
公开(公告)日：2011-01-06
申请号：US12811778
申请日：2009-01-02
申请人： Chul Ha Kim , Jong Soo Choi , Jeong Hwan Kim , Hyoung Seok Kim , Jung Gun Kwon , Tae Min Ahn , Soo Youn Hwang , Jae Ick Sim , Min Ji Baek , Na Ra Kwon , Hye Jin Choi
发明人： Chul Ha Kim , Jong Soo Choi , Jeong Hwan Kim , Hyoung Seok Kim , Jung Gun Kwon , Tae Min Ahn , Soo Youn Hwang , Jae Ick Sim , Min Ji Baek , Na Ra Kwon , Hye Jin Choi
IPC分类号： C12P19/40 , C12N1/20
CPC分类号： C12P19/40 , C12N9/2497 , C12Y302/02001 , C12Y302/02008
摘要： A microorganism of the genus Corynebacterium having the ability to produce inosine in which the inosine catabolic pathway is blocked and that has a leaky adenine auxotrophic phenotype and further has a leaky guanine auxotrophic phenotype and a method of producing inosine, the method including culturing the microorganism of the genus Corynebacterium are disclosed.
摘要翻译：能够产生肌苷分解代谢途径被阻断并具有渗漏的腺嘌呤营养缺陷型的肌氨酸杆菌属的微生物，并且还具有泄漏的鸟嘌呤营养缺陷型表型和产生肌苷的方法，该方法包括培养微生物披露了棒状杆菌属。

6. 发明授权

US09005952B2 Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism 有权
标题翻译：生产L-甲硫氨酸前体的微生物和使用该微生物生产L-甲硫氨酸前体的方法
公开(公告)号：US09005952B2
公开(公告)日：2015-04-14
申请号：US12062835
申请日：2008-04-04
申请人： Chul Ha Kim , So Young Kim , Young Uk Shin , Hye Won Um , Jin Sook Chang , Young Wook Cho , Han Jin Lee , In Kyung Heo , Chang Il Seo , Kwang Ho Na
发明人： Chul Ha Kim , So Young Kim , Young Uk Shin , Hye Won Um , Jin Sook Chang , Young Wook Cho , Han Jin Lee , In Kyung Heo , Chang Il Seo , Kwang Ho Na
IPC分类号： C12P13/12 , C12N1/00 , C12N15/00 , C12N1/20 , C12N9/04 , C12N9/10 , C12Q1/68 , C07H21/04 , C12N9/12 , C12P13/06 , C12R1/19
CPC分类号： C12N1/20 , C12N9/0006 , C12N9/1029 , C12N9/1217 , C12P13/06 , C12P13/12 , C12R1/19
摘要： The present invention relates to a microorganism producing L-methionine precursor, O-acetylhomoserine, and a method of producing L-methionine precursor using the microorganism.
摘要翻译：本发明涉及生产L-甲硫氨酸前体的微生物O-乙酰高丝氨酸，以及使用该微生物生产L-甲硫氨酸前体的方法。

7. 发明申请

US20110189739A1 ESCHERICHIA COLI STRAIN WITH ENHANCED L-THREONINE PRODUCTIVITY AND METHOD OF PRODUCING L-THREONINE USING THE SAME 有权
标题翻译：具有增强的L-苏氨酸生产力的ESCHERICHIA COLI菌株和使用该柠檬酸生产L-赖氨酸的方法
公开(公告)号：US20110189739A1
公开(公告)日：2011-08-04
申请号：US12812203
申请日：2009-01-07
申请人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
发明人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
IPC分类号： C12P13/08 , C12N1/21
CPC分类号： C12P13/08 , C12N9/1085 , C12N9/88
摘要： An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
摘要翻译：公开了其中染色体上的磷酸烯醇式丙酮酸羧化酶（ppc）基因的启动子被半胱氨酸合成酶（cysK）基因的启动子取代的产生L-苏氨酸的大肠杆菌以及通过使用它们产生L-苏氨酸的方法。重组大肠杆菌可以以高产率生产L-苏氨酸，因此可广泛用于医药，制药和饲料工业，特别是用于动物饲料。

8. 发明授权

US06707524B2 Fringe field switching mode liquid crystal display, and fabrication method therefor 有权
标题翻译：边缘场开关模式液晶显示器及其制造方法
公开(公告)号：US06707524B2
公开(公告)日：2004-03-16
申请号：US09997794
申请日：2001-11-30
申请人： Chul Ha Kim , Hee Chul Jung , Pyung Soo Ha , Chi Wook An
发明人： Chul Ha Kim , Hee Chul Jung , Pyung Soo Ha , Chi Wook An
IPC分类号： G02F11368
CPC分类号： G02F1/134363
摘要： The present invention relates to a fringe field switching mode liquid crystal display, comprising: gate lines and data lines aligned on a transparent insulating substrate to vertically cross each other; common electrode lines aligned horizontally to the gate lines; a pixel region defined in a space formed by the gate lines and data lines; a first transparent electrode formed in the pixel region, and divided into at least two regions; and a second transparent electrode insulated from the first transparent electrode, and divided on the first transparent electrode as many as the first transparent electrode, a data voltage being applied to the second transparent electrode in a first region and to the first transparent electrode in a second region, a sum of the voltages applied to the pixel region having a zero voltage.
摘要翻译：边缘场开关模式液晶显示器技术领域本发明涉及一种边缘场开关模式液晶显示器，包括：在透明绝缘基板上对准的垂直交叉的栅极线和数据线; 公共电极线与栅极线水平对准; 限定在由栅极线和数据线形成的空间中的像素区域; 形成在所述像素区域中并分成至少两个区域的第一透明电极; 和与第一透明电极绝缘的第二透明电极，并分割成与第一透明电极一样多的第一透明电极，在第一区域中施加到第二透明电极的数据电压和第二透明电极的第二透明电极区域，施加到具有零电压的像素区域的电压的和。

9. 发明授权

US07851180B2 Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism 有权
标题翻译：生产L-甲硫氨酸前体的微生物和使用该微生物生产L-甲硫氨酸前体的方法
公开(公告)号：US07851180B2
公开(公告)日：2010-12-14
申请号：US12062927
申请日：2008-04-04
申请人： Young Uk Shin , So Young Kim , Jin Sook Chang , Young Wook Cho , Han Jin Lee , In Kyung Heo , Kwang Ho Na , Chang Il Seo , Chul Ha Kim , Hye Won Um
发明人： Young Uk Shin , So Young Kim , Jin Sook Chang , Young Wook Cho , Han Jin Lee , In Kyung Heo , Kwang Ho Na , Chang Il Seo , Chul Ha Kim , Hye Won Um
IPC分类号： C12N1/12 , C12N1/20 , C12P1/00
CPC分类号： C12P13/06 , C12N9/1029
摘要： The present invention relates to a microorganism producing L-methionine precursor, O-succinylhomoserine, and a method of producing L-methionine precursor using the microorganism,
摘要翻译：本发明涉及生产L-甲硫氨酸前体的微生物，O-琥珀酰高丝氨酸，以及使用该微生物生产L-甲硫氨酸前体的方法，

10. 发明授权

US08455237B2 Escherichia coli strain with phosphoenolpyruvate carboxylase promoter replaced with cysteine synthase promoter and method of enhanced production of L-threonine using the same 有权
标题翻译：具有用半胱氨酸合成酶启动子取代的具有磷酸烯醇丙酮酸羧化酶启动子的大肠杆菌菌株和使用其同时增强L-苏氨酸生产的方法
公开(公告)号：US08455237B2
公开(公告)日：2013-06-04
申请号：US12812203
申请日：2009-01-07
申请人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
发明人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
IPC分类号： C12N1/20
CPC分类号： C12P13/08 , C12N9/1085 , C12N9/88
摘要： An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
摘要翻译：公开了其中染色体上的磷酸烯醇式丙酮酸羧化酶（ppc）基因的启动子被半胱氨酸合成酶（cysK）基因的启动子取代的产生L-苏氨酸的大肠杆菌以及通过使用它们产生L-苏氨酸的方法。重组大肠杆菌可以以高产率生产L-苏氨酸，因此可广泛用于医药，制药和饲料工业，特别是用于动物饲料。

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