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1. 发明申请

US20050116159A1 Mass spectrometic quantification of chemical mixture components 有权
标题翻译：化学混合物组分的质谱定量
公开(公告)号：US20050116159A1
公开(公告)日：2005-06-02
申请号：US11023234
申请日：2004-12-27
申请人： Christopher Becker , Curtis Hastings , Scott Norton , Sushmita Roy , Weixun Wang , Haihong Zhou , Thomas Shaler , Praveen Kumar , Markus Anderle , Hua Lin
发明人： Christopher Becker , Curtis Hastings , Scott Norton , Sushmita Roy , Weixun Wang , Haihong Zhou , Thomas Shaler , Praveen Kumar , Markus Anderle , Hua Lin
IPC分类号： H01J49/04 , H01J49/00
CPC分类号： H01J49/0036
摘要： Relative quantitative information about components of chemical or biological samples can be obtained from mass spectra by normalizing the spectra to yield peak intensity values that accurately reflect concentrations of the responsible species. A normalization factor is computed from peak intensities of those inherent components whose concentration remains constant across a series of samples. Relative concentrations of a component occurring in different samples can be estimated from the normalized peak intensities. Unlike conventional methods, internal standards or additional reagents are not required. The methods are particularly useful for differential phenotyping in proteomics and metabolomics research, in which molecules varying in concentration across samples are identified. These identified species may serve as biological markers for disease or response to therapy.
摘要翻译：通过对光谱进行归一化，可以从质谱中获得关于化学或生物样品成分的相对定量信息，以产生准确反映负责物种浓度的峰值强度值。归一化因子是由浓度在一系列样品中保持不变的那些固有成分的峰值强度计算出来的。发生在不同样品中的组分的相对浓度可以从标准化峰强度估计。与传统方法不同，不需要内标或附加试剂。该方法对于蛋白质组学和代谢组学研究中的差异表型特别有用，其中鉴定了样品浓度变化的分子。这些鉴定的物种可以作为疾病或治疗反应的生物标志物。

2. 发明授权

US07087896B2 Mass spectrometric quantification of chemical mixture components 有权
标题翻译：化学混合物组分的质谱定量
公开(公告)号：US07087896B2
公开(公告)日：2006-08-08
申请号：US11023234
申请日：2004-12-27
申请人： Christopher H. Becker , Curtis A. Hastings , Scott M. Norton , Sushmita Mimi Roy , Weixun Wang , Haihong Zhou , Thomas Andrew Shaler , Praveen Kumar , Markus Anderle , Hua Lin
发明人： Christopher H. Becker , Curtis A. Hastings , Scott M. Norton , Sushmita Mimi Roy , Weixun Wang , Haihong Zhou , Thomas Andrew Shaler , Praveen Kumar , Markus Anderle , Hua Lin
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/0036
摘要： Relative quantitative information about components of chemical or biological samples can be obtained from mass spectra by normalizing the spectra to yield peak intensity values that accurately reflect concentrations of the responsible species. A normalization factor is computed from peak intensities of those inherent components whose concentration remains constant across a series of samples. Relative concentrations of a component occurring in different samples can be estimated from the normalized peak intensities. Unlike conventional methods, internal standards or additional reagents are not required. The methods are particularly useful for differential phenotyping in proteomics and metabolomics research, in which molecules varying in concentration across samples are identified. These identified species may serve as biological markers for disease or response to therapy.
摘要翻译：通过对光谱进行归一化，可以从质谱中获得关于化学或生物样品成分的相对定量信息，以产生准确反映负责物种浓度的峰值强度值。归一化因子是由浓度在一系列样品中保持不变的那些固有成分的峰值强度计算出来的。发生在不同样品中的组分的相对浓度可以从标准化峰强度估计。与传统方法不同，不需要内标或附加试剂。该方法对于蛋白质组学和代谢组学研究中的差异表型特别有用，其中鉴定了样品浓度变化的分子。这些鉴定的物种可以作为疾病或治疗反应的生物标志物。

3. 发明授权

US08205013B2 Method and system for aggregating the control of middleware control points 有权
标题翻译：集中控制中间件控制点的方法和系统
公开(公告)号：US08205013B2
公开(公告)日：2012-06-19
申请号：US11121820
申请日：2005-05-02
申请人： Hoyong Park , Praveen Kumar , Alan Messer , Victor Zhu
发明人： Hoyong Park , Praveen Kumar , Alan Messer , Victor Zhu
IPC分类号： G06F15/16
CPC分类号： H04L41/12 , H04L67/2838
摘要： A method of aggregating control in a first network and a second network, the first network having first devices and the second network having second devices. A communication channel is established between the first and second networks; from the first network the second devices in the second network are discovered through the communication channel; and from the first network one of the second devices in the second network is controlled through the communication channel. The first and second network can be connected but isolated. Further, the first and second networks can implement different network protocols, or the same network protocol.
摘要翻译：一种在第一网络和第二网络中聚合控制的方法，所述第一网络具有第一设备，所述第二网络具有第二设备。在第一和第二网络之间建立通信信道; 从第一网络通过通信信道发现第二网络中的第二设备; 并且从第一网络通过通信信道来控制第二网络中的第二设备之一。第一个和第二个网络可以连接但是隔离。此外，第一和第二网络可以实现不同的网络协议或相同的网络协议。

4. 发明申请

US20110299472A1 Adaptive Synchronization scheme for wireless communication systems 审中-公开
标题翻译：无线通信系统的自适应同步方案
公开(公告)号：US20110299472A1
公开(公告)日：2011-12-08
申请号：US13201911
申请日：2010-02-11
申请人： Praveen Kumar
发明人： Praveen Kumar
IPC分类号： H04W4/00
CPC分类号： H04W56/001 , H04B7/2656 , Y02D70/144 , Y02D70/164 , Y02D70/22 , Y02D70/449
摘要： A method and system for synchronization in a wireless communication network using a plurality of synchronization frames (SF) and ciao frames (CF) distributed across a configurable period, termed as synchronization activity period (SAP) is disclosed. The periodicity of the SAP could be configured, to align with the data exchange periodicity. The length of the SAP is configurable; it is directly proportional to its periodicity and inversely proportional to the number of attempts and duration the unsynchronized nodes will make to listen to the synchronization information. This method provides a mechanism in which the network can configure the synchronization periodicity based on the data exchange periodicity and also it distributes the synchronization load among all its associated nodes to optimize the power efficiency.
摘要翻译：公开了一种在无线通信网络内同步的方法和系统，该方法和系统使用分布在可配置周期内的多个同步帧（SF）和小帧（CF），被称为同步活动周期（SAP）。可以配置SAP的周期性，以便与数据交换周期一致。 SAP的长度可配置; 它与其周期性成正比，并且与不同步节点将监听同步信息的尝试次数和持续时间成反比。该方法提供了一种机制，其中网络可以基于数据交换周期来配置同步周期，并且在所有相关联的节点之间分配同步负载以优化功率效率。

5. 发明申请

US20100196453A1 BIPHASIC LIPID-VESICLE COMPOSITION AND METHOD FOR TREATING CERVICAL DYSPLASIA BY INTRAVAGINAL DELIVERY 有权
标题翻译：双向脂肪组合物和通过腹腔内输送治疗宫颈粘液的方法
公开(公告)号：US20100196453A1
公开(公告)日：2010-08-05
申请号：US12532752
申请日：2008-03-27
申请人： Marianna Foldvari , Praveen Kumar , John M. Docherty
发明人： Marianna Foldvari , Praveen Kumar , John M. Docherty
IPC分类号： A61K38/21 , A61K9/127 , A61P15/00
CPC分类号： A61K9/127 , A61K9/0034 , A61K9/10 , A61K9/1075 , A61K9/1277 , A61K31/198 , A61K38/21 , A61K38/212 , A61K47/183
摘要： A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks.
摘要翻译：用于通过阴道内递送治疗宫颈置换的双相脂质囊泡组合物。该组合物包括其中包含的脂质 - 双层囊泡的悬浮液，水包油乳剂，人类干扰素α-2b和L-甲硫氨酸，所述组合物具有约1-10MIU的干扰素α-2b特异活性（百万国际单位），和0.01-0.5重量百分比的L-甲硫氨酸。在治疗方法中，组合物以约1-20MIU干扰素α-2b的剂量施用，并且该剂量至少3天/周施用至少4周的时间。

6. 发明申请

US20090228432A1 Query Rewrite With A Nested Materialized View 有权
标题翻译：使用嵌套物化视图进行查询重写
公开(公告)号：US20090228432A1
公开(公告)日：2009-09-10
申请号：US12043908
申请日：2008-03-06
申请人： Murali Thiyagarajan , Praveen Kumar
发明人： Murali Thiyagarajan , Praveen Kumar
IPC分类号： G06F17/30
CPC分类号： G06F17/30457
摘要： A query, issued to a database server, is re-written with a nested materialized view. The selected materialized view is nested within a “parent” materialized view that has one or more nesting levels for one or more nested materialized views. The selected nested materialized view has a cardinality associated therewith, which is lower than the cardinality associated with any of the other nested materialized views, and is nested at a final nesting level of the one or more nesting levels.
摘要翻译：发布到数据库服务器的查询将重新写入嵌套实例化视图。所选物化视图嵌套在“父”物化视图中，该视图具有一个或多个嵌套实例化视图的一个或多个嵌套级别。所选择的嵌套实体化视图具有与其相关联的基数，其低于与任何其他嵌套实现视图相关联的基数，并且嵌套在所述一个或多个嵌套级别的最终嵌套级别。

7. 发明申请

US20070050630A1 Authentication method and system for asynchronous eventing over the internet 审中-公开
标题翻译：通过互联网异步事件的认证方法和系统
公开(公告)号：US20070050630A1
公开(公告)日：2007-03-01
申请号：US11354405
申请日：2006-02-14
申请人： Praveen Kumar , Yu Song , Alan Messer , Doreen Cheng
发明人： Praveen Kumar , Yu Song , Alan Messer , Doreen Cheng
IPC分类号： H04L9/00
CPC分类号： H04L63/08 , H04L63/18
摘要： An authentication method and system is provided for asynchronous eventing between a client and a server over the Internet. In a subscription phase, the client sends a subscription request to the server to express interest in receiving notifications associated with one or more particular events that may asynchronously occur on the server. The client authenticates the server by checking the identity of the server, and if the client determines that the server can be trusted, the client subscribes the notifications, otherwise, the client does not subscribe. After a successful subscription, in a notification phase, the server notifies each client that has subscribed for a particular type of event. Each client upon receiving a notification, authenticates the server by verifying that the received notification is sent by the server with which the client subscribed for the notification.
摘要翻译：提供了通过因特网在客户机和服务器之间异步事件的认证方法和系统。在订阅阶段，客户端向服务器发送订阅请求，以表示感兴趣地接收与可能在服务器上异步发生的一个或多个特定事件相关联的通知。客户端通过检查服务器的身份来验证服务器，并且如果客户端确定服务器可以被信任，则客户端订阅通知，否则客户端不进行订阅。订阅成功后，在通知阶段，服务器通知已订阅特定类型事件的每个客户端。每个客户端在收到通知后，通过验证接收到的通知是由客户端订阅通知的服务器发送来验证服务器。

8. 发明申请

US20050078745A1 System and method for auto baud rate detection in asynchronous serial communication 有权
标题翻译：异步串行通信中自动波特率检测的系统和方法
公开(公告)号：US20050078745A1
公开(公告)日：2005-04-14
申请号：US10683887
申请日：2003-10-09
申请人： Sangeeta Sinha , Praveen Kumar
发明人： Sangeeta Sinha , Praveen Kumar
IPC分类号： H04B3/46 , H04B17/00 , H04L25/02 , H04Q1/20
CPC分类号： H04L25/0262
摘要： A microcontroller with embedded software for automatically detecting a baud rate of an asynchronous serial bit stream during an initial set up phase of a microcontroller. The microcontroller is configured to receive a data set from a transmitter and includes a transition detector for identifying bit transitions in the data set. The microcontroller includes a timer triggered by the transition detector that is measures the time interval between two predefined bit transitions, a storage element for registering the measured time interval, and a look up table that provides defines baud rates relative to various time intervals that can be accessed to determine a nearest baud rate value corresponding to the registered time interval.
摘要翻译：具有嵌入式软件的微控制器，用于在微控制器的初始设置阶段期间自动检测异步串行位流的波特率。微控制器被配置为从发射机接收数据组，并且包括用于识别数据组中的位转换的转换检测器。微控制器包括由转换检测器触发的定时器，该定时器测量两个预定义位转换之间的时间间隔，用于记录所测量的时间间隔的存储元件，以及提供相对于各种时间间隔定义波特率的查找表被访问以确定对应于注册的时间间隔的最近的波特率值。

9. 发明授权

US08945529B2 Biphasic lipid-vesicle compositions 有权
标题翻译：双相脂质囊泡组合物
公开(公告)号：US08945529B2
公开(公告)日：2015-02-03
申请号：US12532752
申请日：2008-03-27
申请人： Marianna Foldvari , Praveen Kumar , John M. Docherty
发明人： Marianna Foldvari , Praveen Kumar , John M. Docherty
IPC分类号： A61K38/21 , A61K9/127 , A61K38/00 , A61K9/00 , A61K31/198 , A61K47/18 , A61K9/10 , A61K9/107
CPC分类号： A61K9/127 , A61K9/0034 , A61K9/10 , A61K9/1075 , A61K9/1277 , A61K31/198 , A61K38/21 , A61K38/212 , A61K47/183
摘要： A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks.
摘要翻译：用于通过阴道内递送治疗宫颈置换的双相脂质囊泡组合物。该组合物包括其中包含脂质 - 双层囊泡的悬浮液，水包油乳剂，人类干扰素α-2b和L-甲硫氨酸，所述组合物具有约1-10MIU的干扰素α-2b比活性（百万国际单位），和0.01-0.5重量百分比的L-甲硫氨酸。在治疗方法中，组合物以约1-20MIU干扰素α-2b的剂量施用，并且该剂量至少3天/周施用至少4周的时间。

10. 发明申请

US20110299426A1 Starting a Wireless Communications Network using wireless signal 审中-公开
标题翻译：启动使用无线信号的无线通信网络
公开(公告)号：US20110299426A1
公开(公告)日：2011-12-08
申请号：US13201923
申请日：2010-02-11
申请人： Praveen Kumar
发明人： Praveen Kumar
IPC分类号： H04W52/02 , H04W84/10
CPC分类号： H04W52/0235 , Y02D70/144
摘要： Embodiments herein provide a method and system for switching a wireless device from low power consumption dormant mode to active mode in a wireless communication network (WCN) using a switch command frame (SCF). The SCF is transmitted repeatedly for continuous configurable period of time, long enough to provide multiple opportunities to the dormant nodes to listen to the same and change its mode appropriately. This invention improves the power efficiency of the node when it is not associated with any network.
摘要翻译：这里的实施例提供了一种使用切换命令帧（SCF）在无线通信网络（WCN）中将无线设备从低功耗休眠模式切换到活动模式的方法和系统。 SCF在连续可配置的时间段内被重复传输，足够长的时间为休眠节点提供多个机会来收听并适当地改变其模式。本发明在不与任何网络相关联的情况下提高节点的功率效率。

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