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1. 发明申请

US20060148058A1 Organic compounds 审中-公开
标题翻译：有机化合物
公开(公告)号：US20060148058A1
公开(公告)日：2006-07-06
申请号：US11343891
申请日：2006-01-31
申请人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Muller , Oliver Ottmann , Markus Warmuth
发明人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Muller , Oliver Ottmann , Markus Warmuth
IPC分类号： C12N9/12
CPC分类号： C12Q1/6886 , C07K14/82 , C12N9/12 , C12Q1/485 , C12Q2600/106 , G01N33/57426 , G01N2333/82
摘要： The tides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit they tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.
摘要翻译：包含由突变的功能性Ab1激酶结构域组成的氨基酸序列的所述突变体，所述突变的功能性激酶结构域对N- [4-甲基-3-（4-吡啶-3-基 - 嘧啶-2-基氨基） - 苯基] -4-（4-甲基 - 哌嗪-1-基甲基） - 苯甲酰胺或其盐，用于筛选抑制这些多肽的酪氨酸激酶活性的化合物，涉及编码这种多肽的核酸分子，重组载体和包含此类核酸分子的宿主细胞，以及这些核酸分子在产生此类多肽中的用途，用于筛选抑制这些多肽的酪氨酸激酶活性的化合物。

2. 发明申请

US20090191606A1 ORGANIC COMPOUNDS 审中-公开
标题翻译：有机化合物
公开(公告)号：US20090191606A1
公开(公告)日：2009-07-30
申请号：US12337322
申请日：2008-12-17
申请人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Jay Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Muller , Oliver Gerhard Ottmann , Markus Warmuth
发明人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Jay Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Muller , Oliver Gerhard Ottmann , Markus Warmuth
IPC分类号： C12N9/12 , C07H21/00 , C12N15/63 , C12N5/10
CPC分类号： C12Q1/6886 , C07K14/82 , C12N9/12 , C12Q1/485 , C12Q2600/106 , G01N33/57426 , G01N2333/82
摘要： The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1 -ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.
摘要翻译：本发明涉及分离的多肽，其包含由突变的功能性Ab1激酶结构域组成的氨基酸序列，所述突变的功能性激酶结构域对N- [4-甲基-3-（4-吡啶基）吡啶-3-基 - 嘧啶-2-基氨基） - 苯基] -4-（4-甲基 - 哌嗪-1-基甲基） - 苯甲酰胺或其盐，用于筛选抑制酪氨酸激酶的化合物这种多肽的活性，编码这种多肽的核酸分子，重组载体和包含此类核酸分子的宿主细胞，以及这种核酸分子在制备这些多肽中的用途，用于筛选抑制酪氨酸激酶的化合物这些多肽的活性。

3. 发明申请

US20110129852A1 ORGANIC COMPOUNDS 审中-公开
标题翻译：有机化合物
公开(公告)号：US20110129852A1
公开(公告)日：2011-06-02
申请号：US12834628
申请日：2010-07-12
申请人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Jay Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Müller , Oliver Gerhard Ottmann , Markus Warmuth
发明人： Christophe Barthe , Pascale Cony-Makhoul , Amie Corbin , Sven De Vos , Brian Jay Druker , Harald Gschaidmeier , Michael Hallek , Andreas Hochhaus , Dieter Hoelzer , Wolf-Karsten Hofmann , Phillip Koeffler , Sebastian Kreil , Francois-Xavier Mahon , Martin Müller , Oliver Gerhard Ottmann , Markus Warmuth
IPC分类号： C12N9/12 , C07H21/04 , G01N33/53 , C12N15/63 , C12N5/10
CPC分类号： C12Q1/6886 , C07K14/82 , C12N9/12 , C12Q1/485 , C12Q2600/106 , G01N33/57426 , G01N2333/82
摘要： The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.
摘要翻译：本发明涉及分离的多肽，其包含由突变的功能性Ab1激酶结构域组成的氨基酸序列，所述突变的功能性激酶结构域对N- [4-甲基-3-（4-吡啶基）吡啶-3-基 - 嘧啶-2-基氨基） - 苯基] -4-（4-甲基 - 哌嗪-1-基甲基） - 苯甲酰胺或其盐，用于筛选抑制酪氨酸激酶的化合物这种多肽的活性，编码这种多肽的核酸分子，重组载体和包含此类核酸分子的宿主细胞，以及这种核酸分子在制备这些多肽中的用途，用于筛选抑制酪氨酸激酶的化合物这些多肽的活性。

4. 发明申请

US20070027167A1 Use of c-Src inhibitors alone or in combinaton with STI571 for the treatment of leukaemia 审中-公开
标题翻译：单独使用c-Src抑制剂或与STI571组合用于治疗白血病
公开(公告)号：US20070027167A1
公开(公告)日：2007-02-01
申请号：US11515981
申请日：2006-09-05
申请人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/519
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamdio]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine.
摘要翻译：本发明涉及一种组合，其包含（a）至少一种降低c-Src活性的化合物和（b）N- {5- [4-（4-甲基 - 哌嗪基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺或其单甲磺酸盐; 包含所述组合的药物组合物; 以及治疗具有白血病，特别是慢性骨髓性白血病的温血动物的方法，包括向所述动物施用至少一种抑制Src激酶家族成员，Tec激酶家族或Raf激酶抑制剂的活性的化合物，特别是抑制c-Src蛋白酪氨酸激酶活性或同时抑制c-Src蛋白酪氨酸激酶活性和Bcr-Abl酪氨酸激酶活性，单独或与Bcr-Abl抑制剂组合，特别是N- {5- [ 4-（4-甲基 - 哌嗪子基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺。

5. 发明申请

US20060074094A1 Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia 失效
标题翻译：单独或与STI571组合使用c-Src抑制剂治疗白血病
公开(公告)号：US20060074094A1
公开(公告)日：2006-04-06
申请号：US11285664
申请日：2005-11-22
申请人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/519
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Btk kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine.
摘要翻译：本发明涉及一种组合，其包含（a）至少一种降低c-Src活性的化合物和（b）N- {5- [4-（4-甲基 - 哌嗪基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺或其单甲磺酸盐; 包含所述组合的药物组合物; 以及治疗具有白血病，特别是慢性骨髓性白血病的温血动物的方法，包括向所述动物施用至少一种抑制Src激酶家族成员，Btk激酶家族，Tec激酶家族的活性的化合物或 Raf激酶抑制剂，特别是抑制c-Src蛋白酪氨酸激酶活性或同时抑制c-Src蛋白酪氨酸激酶活性和Bcr-Abl酪氨酸激酶活性，单独或与Bcr-Abl抑制剂组合，特别是N - {5- [4-（4-甲基 - 哌嗪子基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺。

6. 发明授权

US08119649B2 Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia 失效
公开(公告)号：US08119649B2
公开(公告)日：2012-02-21
申请号：US12466186
申请日：2009-05-14
申请人： Nicholas J Donato , Doriano Fabbro , Paul W Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas J Donato , Doriano Fabbro , Paul W Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/519
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Btk kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine.

7. 发明申请

US20090227608A1 USE OF C-SRC INHIBITORS ALONE OR IN COMBINATION WITH STI571 FOR THE TREATMENT OF LEUKAEMIA 失效
标题翻译：使用C-SRC抑制剂或与STI571组合用于治疗白血病
公开(公告)号：US20090227608A1
公开(公告)日：2009-09-10
申请号：US12466186
申请日：2009-05-14
申请人： Nicholas J. Donato , Doriano Fabbro , Paul William Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas J. Donato , Doriano Fabbro , Paul William Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/519 , A61P35/00
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Btk kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine.
摘要翻译：本发明涉及一种组合，其包含（a）至少一种降低c-Src活性的化合物和（b）N- {5- [4-（4-甲基 - 哌嗪基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺或其单甲磺酸盐; 包含所述组合的药物组合物; 以及治疗具有白血病，特别是慢性骨髓性白血病的温血动物的方法，包括向所述动物施用至少一种抑制Src激酶家族成员，Btk激酶家族，Tec激酶家族的活性的化合物或 Raf激酶抑制剂，特别是抑制c-Src蛋白酪氨酸激酶活性或同时抑制c-Src蛋白酪氨酸激酶活性和Bcr-Abl酪氨酸激酶活性，单独或与Bcr-Abl抑制剂组合，特别是N - {5- [4-（4-甲基 - 哌嗪子基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺。

8. 发明授权

US08268837B2 Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia 失效
标题翻译：单独或与STI571组合使用c-Src抑制剂治疗白血病
公开(公告)号：US08268837B2
公开(公告)日：2012-09-18
申请号：US11285664
申请日：2005-11-22
申请人： Nicholas J Donato , Doriano Fabbro , Paul W Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas J Donato , Doriano Fabbro , Paul W Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/519
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Btk kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine.
摘要翻译：本发明涉及一种组合，其包含（a）至少一种降低c-Src活性的化合物和（b）N- {5- [4-（4-甲基 - 哌嗪基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺或其单甲磺酸盐; 包含所述组合的药物组合物; 以及治疗具有白血病，特别是慢性骨髓性白血病的温血动物的方法，包括向所述动物施用至少一种抑制Src激酶家族成员，Btk激酶家族，Tec激酶家族的活性的化合物或 Raf激酶抑制剂，特别是抑制c-Src蛋白酪氨酸激酶活性或同时抑制c-Src蛋白酪氨酸激酶活性和Bcr-Abl酪氨酸激酶活性，单独或与Bcr-Abl抑制剂组合，特别是N - {5- [4-（4-甲基 - 哌嗪子基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺。

9. 发明申请

US20070149539A1 USE OF C-SRC INHIBITORS ALONE OR IN COMBINATION WITH STI571 FOR THE TREATMENT OF LEUKAEMIA 审中-公开
标题翻译：使用C-SRC抑制剂或与STI571组合用于治疗白血病
公开(公告)号：US20070149539A1
公开(公告)日：2007-06-28
申请号：US11679901
申请日：2007-02-28
申请人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
发明人： Nicholas Donato , Doriano Fabbro , Paul Manley , Jurgen Mestan , Markus Warmuth , Michael Hallek , Moshe Talpaz , Ji Wu
IPC分类号： A61K31/506 , A61K31/497 , A61K31/519
CPC分类号： A61K35/02 , A61K31/506 , A61K31/519
摘要： The invention relates to a combination which comprises (a) at least one compound decreasing the c-Src activity and (b) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamdio]-2-methylphenyl }-4-(3-pyridyl)-2-pyrimidine-amine or the monomethanesulfonate salt thereof; to pharmaceutical compositions comprising said combinations; and to a method of treating a warm-blooded animal having leukaemia, especially chronic myelogenous leukaemia, comprising administering to the animal at least one compound inhibiting the activity of a member of the Src kinase family, the Tec kinase family or a Raf kinase inhibitor, in particular inhibiting the c-Src protein tyrosine kinase activity or inhibiting simultaneously the c-Src protein tyrosine kinase activity and the Bcr-Abl tyrosine kinase activity, alone or in combination with a Bcr-Abl inhibitor, in particular N- {5- [4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl }-4-(3-pyridyl)-2-pyrimidine-amine.
摘要翻译：本发明涉及一种组合，其包含（a）至少一种降低c-Src活性的化合物和（b）N- {5- [4-（4-甲基 - 哌嗪基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺或其单甲磺酸盐; 包含所述组合的药物组合物; 以及治疗具有白血病，特别是慢性骨髓性白血病的温血动物的方法，包括向动物施用至少一种抑制Src激酶家族成员，Tec激酶家族或Raf激酶抑制剂的活性的化合物，特别是抑制c-Src蛋白酪氨酸激酶活性或同时抑制c-Src蛋白酪氨酸激酶活性和Bcr-Abl酪氨酸激酶活性，单独或与Bcr-Abl抑制剂组合，特别是N- {5- [ 4-（4-甲基 - 哌嗪子基 - 甲基） - 苯甲酰氨基] -2-甲基苯基} -4-（3-吡啶基）-2-嘧啶胺。

10. 发明授权

US09514645B2 Driver assistance device having a plurality of ultrasound sensors and vehicle having such a driver assistance device and method for operating a driver assistance device 有权
标题翻译：具有多个超声波传感器的驾驶员辅助装置和具有驾驶员辅助装置和驾驶辅助装置的操作方法的车辆
公开(公告)号：US09514645B2
公开(公告)日：2016-12-06
申请号：US14119572
申请日：2012-05-25
申请人： Michael Hallek
发明人： Michael Hallek
IPC分类号： B60Q1/48 , G08G1/16 , G01S7/524 , G01S15/93 , G01S15/87 , G01S7/537 , G01S15/10 , G01S15/32
CPC分类号： G08G1/16 , G01S7/524 , G01S7/537 , G01S15/102 , G01S15/325 , G01S15/878 , G01S15/931 , G01S2015/938 , G08G1/165 , G08G1/166 , G08G1/167 , G08G1/168
摘要： The invention relates to a driver assistance device (2) having a plurality of ultrasound sensors, wherein at least one first ultrasound sensor (8 to 11, 17, 18, 21 to 24) has a normal mode as an operating mode in which transmitted ultrasound signals are unencoded and/or in which the first ultrasound sensor (8 to 11, 17, 18, 21 to 24) is designed for receiving unencoded ultrasound signals, and at least one second ultrasound sensor (6, 7, 13 to 16, 19, 20) can be operated in two different operating modes and has the normal mode as a first operating mode and has a special mode as a second operating mode, in which transmitted ultrasound signals are encoded and/or in which the second ultrasound sensor (6, 7, 13 to 16, 19, 20) is designed for receiving encoded ultrasound signals. The invention also relates to a vehicle (1) having a driver assistance device (2) and a method for operating a driver assistance device (2).
摘要翻译：本发明涉及一种具有多个超声波传感器的驾驶员辅助装置（2），其中至少一个第一超声波传感器（8至11,17,18,21至24）具有正常模式作为运行模式，其中发射超声波信号未经编码和/或其中第一超声波传感器（8至11,17,18,21至24）被设计用于接收未编码的超声信号，以及至少一个第二超声波传感器（6,7，13至16,19），20）可以以两种不同的操作模式操作，并且具有正常模式作为第一操作模式，并且具有作为第二操作模式的特殊模式，其中传输的超声信号被编码和/或其中第二超声波传感器（6），7,13〜16,19,20）被设计用于接收编码的超声信号。本发明还涉及具有驾驶员辅助装置（2）的车辆（1）和用于操作驾驶员辅助装置（2）的方法。

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