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1. 发明授权

US09579396B2 Finite fully addressable nucleic acid nanostructures as nanocarriers for delivery of pharmaceuticals 有权
标题翻译：有限的完全可寻址的核酸纳米结构作为药物递送的纳米载体
公开(公告)号：US09579396B2
公开(公告)日：2017-02-28
申请号：US14115600
申请日：2012-05-04
申请人： Chris Dwyer , Hong Zhong , Michael Norton , Steven Armentrout
发明人： Chris Dwyer , Hong Zhong , Michael Norton , Steven Armentrout
IPC分类号： A61K48/00 , A61K47/48 , A61K38/16 , A61K31/7052 , A61K31/337 , A61K39/385 , A61K39/00 , A61K31/7088 , A61K38/00
CPC分类号： A61K47/48884 , A61K31/337 , A61K31/7052 , A61K31/7088 , A61K38/00 , A61K38/164 , A61K39/385 , A61K47/48092 , A61K47/549 , A61K47/6929 , A61K48/00 , A61K2039/6025 , Y10T428/2982
摘要： The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest in vivo, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.
摘要翻译：本发明提供了纳米结构，其特别适用于在体内向感兴趣的器官，组织和细胞递送生物活性剂，并用于诊断目的。在示例性实施方案中，纳米结构是具有完全限定的核苷酸序列的DNA链的复合物，其以彼此杂交以提供具有用于靶向分子和生物活性剂的结合位点的预先设计的三维结构。纳米结构具有预先设计的有限长度并且具有预定义的三维结构。

2. 发明申请

US20100125864A1 MOBILE REMOTE CONTROL OF A SHARED MEDIA RESOURCE 审中-公开
公开(公告)号：US20100125864A1
公开(公告)日：2010-05-20
申请号：US12272757
申请日：2008-11-17
申请人： Chris Dwyer , Peter Lange , Robert Clark , John Board , Alex Edelsburg , Zachary Drillings
发明人： Chris Dwyer , Peter Lange , Robert Clark , John Board , Alex Edelsburg , Zachary Drillings
IPC分类号： H04N7/173 , G06F21/00 , H04W4/00
CPC分类号： G06Q10/10 , H04N21/41407 , H04N21/4316 , H04N21/4756 , H04N21/8456 , H04W4/12
摘要： Systems and methods for controlling a shared media resource are disclosed. One embodiment includes an edge device adapted to control the media resource based on content selection votes received from users in the shared space who transmit their votes to the edge device over a wide area communication network. In a particular example, a user can submit a vote via a mobile communication method such as text messaging. In another example, votes can be submitted by interacting with a web page or an email program. In another aspect, the edge device tallies the votes and, based on a configuration setting that defines a voting policy, the edge device controls a content selection of the media resource. In another example, the edge device can also receive input from one more local remote control devices that communicate directly with the edge device such as, for example, a standard infrared remote control unit. Depending on a configuration setting, communications from such units may be treated as votes or may override votes received to control the device directly. In another aspect a server coupled to the wide area network is adapted to receive and authenticate vote messages from users in the shared space and provide corresponding vote commands to the edge device. In a particular aspect, authenticating the vote messages includes use of a code that is displayed on the edge device such that a user in the shared space must include the code with the vote message in order for the user's vote to be accounted for in determining a content selection of the shared resource. In a more particular aspect, the code is periodically changed via code updating commands sent from the server to the edge device. In another aspect, an administrative user can interact with the server over the wide area network to set up the edge device and to set or change configuration settings of the edge device. In some alternatives, votes can be tallied and content selection determined on the server rather than the edge device and then the server can send content selection commands for to the edge device for controlling the shared media resource.

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