会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 8. 发明申请
    • SUSTAINED RELEASE FILM FORMULATION FOR HEALING WOUND COMPRISING EPIDERMAL GROWTH FACTOR
    • 持续发布电影制作用于包围人造生长因子的治疗
    • US20090047331A1
    • 2009-02-19
    • US12093551
    • 2006-10-27
    • Sun Hee KimSang Kil LeeMin Suk LeeJoon Pio Hong
    • Sun Hee KimSang Kil LeeMin Suk LeeJoon Pio Hong
    • A61K9/70A61L15/00A61P17/02
    • A61L26/0066A61L15/28A61L26/0023A61L26/0095C08L5/08
    • The present invention relates to a sustained release film formulation for healing wound comprising epidermal growth factor, chitosan, viscosity modifiers, plasticizers, and stabilizers. Specifically, the present invention relates to a sustained release film formulation for healing wound comprising epidermal growth factor as an effective ingredient and chitosan as a main base, and additionally comprising one or more antioxidants selected from the group consisting of EDTA and vitamin C; one or more viscosity modifiers selected from the group consisting of hydroxypropylmethylcellulose, gellan gum and pullulan; and one or more plasticizers selected from the group consisting of glycerin, propylene glycol, polyethylene glycol, polyvinyl alcohol and polyvinylpyrrolidone thereto. When the present film is attached to wound site, it absorbs exudation from wound site, and so is changed to hydrogel to keep wound site humid, which is good for wound-healing. And, the present film has superior attachment property to human body, and antifungal activity. Thus, the present film has more merits than simple ointment/cream formulation.
    • 本发明涉及用于治疗伤口的持续释放膜制剂,其包括表皮生长因子,壳聚糖,粘度调节剂,增塑剂和稳定剂。 具体地,本发明涉及一种用于治疗伤口的持续释放膜制剂,其包含表皮生长因子作为有效成分和壳聚糖作为主要基质,并且还包含一种或多种选自EDTA和维生素C的抗氧化剂; 选自羟丙基甲基纤维素,结冷胶和支链淀粉的一种或多种粘度调节剂; 和一种或多种选自甘油,丙二醇,聚乙二醇,聚乙烯醇和聚乙烯吡咯烷酮的增塑剂。 当本膜附着于伤口部位时,吸收伤口部位的渗出物,因此变为水凝胶,保持伤口部位湿润,有利于伤口愈合。 而且,本发明的膜具有优异的人体附着性和抗真菌活性。 因此,本发明的薄膜比简单的软膏/霜剂具有更多的优点。