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1. 发明授权

US07740759B2 Magnetic separation device 失效
标题翻译：磁选机
公开(公告)号：US07740759B2
公开(公告)日：2010-06-22
申请号：US11736555
申请日：2007-04-17
申请人： Chih Hsien Su , Hsiao Cheng Lin , Chi-Min Chau , Yuh-Jiuan Lin , Wen-Hsun Kuo
发明人： Chih Hsien Su , Hsiao Cheng Lin , Chi-Min Chau , Yuh-Jiuan Lin , Wen-Hsun Kuo
IPC分类号： B01D35/06 , B03C1/02 , B01L9/06
CPC分类号： B03C1/288 , B01L9/06 , B01L2200/0668 , B03C2201/18
摘要： A magnetic separation device separating magnetic material from a working fluid of a container is disclosed. The magnetic separation device includes a first element, a second element and a magnetic assembly structure including a plurality of magnetic units. The first element includes a first body, a plurality of first main positioning portions disposed on the first body, and a plurality of first sub-positioning portions disposed on the first body and next to the first main positioning portions to receive the container. The second element includes a second body, a plurality of second main positioning portions disposed on the second body, and a plurality of second sub-positioning portions disposed on the second body and next to the second main positioning portions to receive the container. The magnetic units disposed on the first main positioning portions and the second main positioning portions absorb magnetic material from the working fluid.
摘要翻译：公开了一种将磁性材料与容器的工作流体分离的磁选机。磁分离装置包括第一元件，第二元件和包括多个磁性单元的磁性组件结构。第一元件包括第一主体，设置在第一主体上的多个第一主定位部以及设置在第一主体上并靠近第一主定位部分以接收容器的多个第一副定位部。第二元件包括第二主体，设置在第二主体上的多个第二主定位部分和设置在第二主体上并与第二主定位部分相邻以接收容器的多个第二副定位部分。设置在第一主定位部分上的磁性单元和第二主定位部分吸收来自工作流体的磁性材料。

2. 发明申请

US20080156714A1 MAGNETIC SEPARATION DEVICE 失效
标题翻译：磁选分离装置
公开(公告)号：US20080156714A1
公开(公告)日：2008-07-03
申请号：US11736555
申请日：2007-04-17
申请人： Chih Hsien Su , Hsiao Cheng Lin , Chi-Min Chau , Yuh-Jiuan Lin , Wen-Hsun Kuo
发明人： Chih Hsien Su , Hsiao Cheng Lin , Chi-Min Chau , Yuh-Jiuan Lin , Wen-Hsun Kuo
IPC分类号： B01D35/06
CPC分类号： B03C1/288 , B01L9/06 , B01L2200/0668 , B03C2201/18
摘要： A magnetic separation device separating magnetic material from a working fluid of a container is disclosed. The magnetic separation device includes a first element, a second element and a magnetic assembly structure including a plurality of magnetic units. The first element includes a first body, a plurality of first main positioning portions disposed on the first body, and a plurality of first sub-positioning portions disposed on the first body and next to the first main positioning portions to receive the container. The second element includes a second body, a plurality of second main positioning portions disposed on the second body, and a plurality of second sub-positioning portions disposed on the second body and next to the second main positioning portions to receive the container. The magnetic units disposed on the first main positioning portions and the second main positioning portions absorb magnetic material from the working fluid.
摘要翻译：公开了一种将磁性材料与容器的工作流体分离的磁选机。磁分离装置包括第一元件，第二元件和包括多个磁性单元的磁性组件结构。第一元件包括第一主体，设置在第一主体上的多个第一主定位部以及设置在第一主体上并靠近第一主定位部分以接收容器的多个第一副定位部。第二元件包括第二主体，设置在第二主体上的多个第二主定位部分和设置在第二主体上并与第二主定位部分相邻以接收容器的多个第二副定位部分。设置在第一主定位部分上的磁性单元和第二主定位部分吸收来自工作流体的磁性材料。

3. 发明授权

US07868145B2 Magnetic particles containing a copolymer core, magnetic layer and silicon layer 有权
标题翻译：含有共聚物芯，磁性层和硅层的磁性颗粒
公开(公告)号：US07868145B2
公开(公告)日：2011-01-11
申请号：US11822958
申请日：2007-07-11
申请人： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau , Chih Hsien Su , Kun Feng Lee
发明人： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau , Chih Hsien Su , Kun Feng Lee
IPC分类号： C07K1/14 , C07K1/22 , C07K17/14 , C07K17/08 , C12P1/00 , C12N11/14 , C12N11/08 , G01N33/553 , G01N33/552 , G01N33/545
CPC分类号： G01N33/5434 , B22F1/02 , B82Y25/00 , C12N13/00 , C22C2202/02 , G01N2446/10 , H01F1/0054 , Y10S435/814 , Y10S530/811 , Y10S530/815 , Y10T428/2993
摘要： A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
摘要翻译：磁性颗粒及其制造方法。磁性颗粒包括聚合物芯，覆盖聚合物芯的磁性材料层和覆盖磁性材料层的含硅层。此外，磁性颗粒还可以包含在含硅层上的偶联剂和与偶联剂连接的活性分子。磁性颗粒提供可控的尺寸，均匀的直径分布，高磁化强度，改善的储存稳定性，以及用于靶向生物分子用于生物材料分离和环境分析的改性表面。

4. 发明申请

US20110166338A1 REAGENT, CHAOTROPIC AGENT, AND REAGENT KIT FOR AND APPLICATIONS OF ISOLATING NUCLEIC ACID BY USE OF MAGNETIC CELLULOSE MATERIAL 有权
标题翻译：通过使用磁性纤维素材料分离核酸的试剂，化学试剂和试剂盒和应用
公开(公告)号：US20110166338A1
公开(公告)日：2011-07-07
申请号：US12935681
申请日：2008-04-02
申请人： Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
发明人： Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
IPC分类号： C07H1/06 , C07H1/08 , H01F1/42
CPC分类号： C07H1/06 , C07H21/00 , C12N15/1013
摘要： Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
摘要翻译：公开了一种离液剂; 包含离液剂和锂盐的试剂; 包含离液剂的试剂盒; 离液剂，试剂，试剂盒和通过使用磁性纤维素材料分离核酸的方法; 将核酸与磁性纤维素材料结合的方法; 分离核酸的方法; 以及纯化染色体DNA的方法。需要每种离液剂，试剂和试剂盒与至少一种固相含磁性纤维素的载体一起工作，以将核酸与非核酸物质分离。此外，各离液剂包括醇物质和用于将醇物质调节至适当浓度的底物溶液，从而促进样品中的核酸与磁性纤维素的结合。

5. 发明授权

US07579436B2 Peptide compound for measuring sulfur compound and ammonia 有权
标题翻译：用于测量硫化合物和氨的肽化合物
公开(公告)号：US07579436B2
公开(公告)日：2009-08-25
申请号：US11681094
申请日：2007-03-01
申请人： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
发明人： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
IPC分类号： C07K7/06
CPC分类号： G01N29/036 , C07K7/06 , G01N33/54373 , G01N33/84 , G01N2291/0257 , Y10T436/175383 , Y10T436/18
摘要： A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the peptide compound to produce a signal, processing the signal to produce a result, and comparing the result with a database to define the presence of the sulfur compound and ammonia in the analyte.
摘要翻译：用于测量硫化合物和氨的肽化合物和使用该化合物的测量方法和装置。该方法包括使分析物与涂覆有肽化合物的感觉装置接触以产生信号，处理信号以产生结果，并将结果与数据库进行比较以定义分析物中硫化合物和氨的存在。

6. 发明授权

US07267989B2 Method and device for measuring sulfur compound and/or ammonia based on a sensory unit coated with at least one novel peptide 有权
标题翻译：用于测量基于涂覆有至少一种新型肽的感官单元的硫化合物和/或氨的方法和装置
公开(公告)号：US07267989B2
公开(公告)日：2007-09-11
申请号：US10321652
申请日：2002-12-18
申请人： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
发明人： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
IPC分类号： G01N33/00
CPC分类号： G01N29/036 , C07K7/06 , G01N33/54373 , G01N33/84 , G01N2291/0257 , Y10T436/175383 , Y10T436/18
摘要： A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the peptide compound to produce a signal, processing the signal to produce a result, and comparing the result with a database to define the presence of the sulfur compound and ammonia in the analyte.
摘要翻译：用于测量硫化合物和氨的肽化合物和使用该化合物的测量方法和装置。该方法包括使分析物与涂覆有肽化合物的感觉装置接触以产生信号，处理信号以产生结果，并将结果与数据库进行比较以定义分析物中硫化合物和氨的存在。

7. 发明授权

US08513405B2 Reagent, chaotropic agent, and reagent kit for and applications of isolating nucleic acid by use of magnetic cellulose material 有权
标题翻译：试剂，离液剂和试剂盒，用于通过使用磁性纤维素材料分离核酸
公开(公告)号：US08513405B2
公开(公告)日：2013-08-20
申请号：US12935681
申请日：2008-04-02
申请人： Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
发明人： Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
IPC分类号： C07H21/02 , C07H21/00
CPC分类号： C07H1/06 , C07H21/00 , C12N15/1013
摘要： Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
摘要翻译：公开了一种离液剂; 包含离液剂和锂盐的试剂; 包含离液剂的试剂盒; 离液剂，试剂，试剂盒和通过使用磁性纤维素材料分离核酸的方法; 将核酸与磁性纤维素材料结合的方法; 分离核酸的方法; 以及纯化染色体DNA的方法。需要每种离液剂，试剂和试剂盒与至少一种固相含磁性纤维素的载体一起工作，以将核酸与非核酸物质分离。此外，各离液剂包括醇物质和用于将醇物质调节至适当浓度的底物溶液，从而促进样品中的核酸与磁性纤维素的结合。

8. 发明申请

US20080114152A1 PEPTIDE COMPOUNDS 有权
标题翻译：肽类化合物
公开(公告)号：US20080114152A1
公开(公告)日：2008-05-15
申请号：US11681094
申请日：2007-03-01
申请人： PEI-CHING SHIH , Pei-shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
发明人： PEI-CHING SHIH , Pei-shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
IPC分类号： C07K7/00
CPC分类号： G01N29/036 , C07K7/06 , G01N33/54373 , G01N33/84 , G01N2291/0257 , Y10T436/175383 , Y10T436/18
摘要： A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the peptide compound to produce a signal, processing the signal to produce a result, and comparing the result with a database to define the presence of the sulfur compound and ammonia in the analyte.
摘要翻译：用于测量硫化合物和氨的肽化合物和使用该化合物的测量方法和装置。该方法包括使分析物与涂覆有肽化合物的感觉装置接触以产生信号，处理信号以产生结果，并将结果与数据库进行比较以定义分析物中硫化合物和氨的存在。

9. 发明申请

US20090017518A1 Magnetic particles and fabrication method thereof 有权
标题翻译：磁性粒子及其制造方法
公开(公告)号：US20090017518A1
公开(公告)日：2009-01-15
申请号：US11822958
申请日：2007-07-11
申请人： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau
发明人： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau
IPC分类号： C12N13/00 , B05D5/12 , B32B5/16
CPC分类号： G01N33/5434 , B22F1/02 , B82Y25/00 , C12N13/00 , C22C2202/02 , G01N2446/10 , H01F1/0054 , Y10S435/814 , Y10S530/811 , Y10S530/815 , Y10T428/2993
摘要： A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
摘要翻译：磁性颗粒及其制造方法。磁性颗粒包括聚合物芯，覆盖聚合物芯的磁性材料层和覆盖磁性材料层的含硅层。此外，磁性颗粒还可以包含在含硅层上的偶联剂和与偶联剂连接的活性分子。磁性颗粒提供可控的尺寸，均匀的直径分布，高磁化强度，改善的储存稳定性，以及用于靶向生物分子用于生物材料分离和环境分析的改性表面。

10. 发明授权

US06605363B2 High-density functional slide and preparation method thereof 有权
公开(公告)号：US06605363B2
公开(公告)日：2003-08-12
申请号：US09836322
申请日：2001-04-18
申请人： Chih-Wei Ho , Zu-Sho Chow , Bor-Iuan Jan , Jia-Huey Tsao , Chao-Chi Pan , Wen-Hsun Kuo , Yao-Sung Chang , Cheng-Tao Wu , Yu-Ching Liu
发明人： Chih-Wei Ho , Zu-Sho Chow , Bor-Iuan Jan , Jia-Huey Tsao , Chao-Chi Pan , Wen-Hsun Kuo , Yao-Sung Chang , Cheng-Tao Wu , Yu-Ching Liu
IPC分类号： B32B904
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00387 , B01J2219/00529 , B01J2219/00576 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00641 , B01J2219/00677 , C07B2200/11 , C40B60/14 , Y10T428/31612 , Y10T428/31663 , Y10T428/31667 , Y10T428/31786 , Y10T428/31938 , Y10T428/31942
摘要： The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.

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