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    • 3. 发明申请
    • Immunochemical assay device
    • 免疫化学测定装置
    • US20050153277A1
    • 2005-07-14
    • US10849109
    • 2004-05-18
    • Kai-Tsung TengSheng-Wen Chang
    • Kai-Tsung TengSheng-Wen Chang
    • C12M1/34C12Q1/70G01N33/53
    • G01N33/5302
    • An immunochemical assay device is proposed. The immunochemical assay device includes a base member, a liquid-flowing layer disposed on the base member and a light-permissible member attached on the liquid-flowing layer. A gap is interposed between the light-permissible member and the liquid-flowing layer, wherein at least an immobilized substance is disposed on the surface of the light-permissible member facing the liquid-flowing layer. The immobilized substance binds to a specific ligand-receptor complex contained in a liquid sample to form an assay marker after the liquid sample has been added into the gap. The liquid sample flows in a microfluidic environment formed between the light-permissible member and the liquid-flowing layer and reacts with the immobilized substance to produce a colored assay marker on the light-permissible member. As the light-permissible member provides better transmission of light than previously known paper materials do, the assay marker can be easily detected by human eyes.
    • 提出了免疫化学测定装置。 免疫化学测定装置包括基底构件,设置在基底构件上的液体流动层和附着在液体流动层上的光允许构件。 在光允许部件和液体流动层之间插入有间隙,其中至少一个固定物质设置在面向液体流通层的光允许部件的表面上。 固定化物质与液体样品中包含的特定配体 - 受体复合物结合,在液体样品加入间隙后形成测定标记。 液体样品在形成在光允许构件和液体流动层之间的微流体环境中流动,并与固定化物质反应,以在光允许构件上产生着色测定标记。 由于光允许部件提供比以前已知的纸材更好的透光性,因此可以容易地通过人眼检测测定标记。